Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress

scientific article published on 28 February 2019

Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-019-39438-1
P932PMC publication ID6395706
P698PubMed publication ID30816308

P50authorMagdalena C E JochnerQ86190843
Ulrich DirnaglQ27870042
Gunnar DittmarQ30504253
Christoph HarmsQ42146749
Gisela TünnemannQ42832350
P2093author name stringBritta J Eickholt
Marieluise Kirchner
Junfeng An
Alina Dagane
P2860cites workPTENα Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial LearningQ50434333
TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure.Q52889320
Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemiasQ58029666
Pyramidal cell regulation of interneuron survival sculpts cortical networksQ59072301
PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.Q64940992
PTENα regulates mitophagy and maintains mitochondrial quality controlQ89406900
Ubiquitination regulates PTEN nuclear import and tumor suppressionQ24292946
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriersQ24654145
A novel role for Gab2 in bFGF-mediated cell survival during retinoic acid-induced neuronal differentiationQ24679348
Pten dose dictates cancer progression in the prostateQ24791909
Fiji: an open-source platform for biological-image analysisQ27860912
PTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolismQ28238905
The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activityQ28269344
A secreted PTEN phosphatase that enters cells to alter signaling and survivalQ28292188
PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppressionQ28505099
Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in MiceQ28595484
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantificationQ29547200
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectorsQ29547596
A short amino acid sequence able to specify nuclear locationQ29547781
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTipsQ29614831
Icy: an open bioimage informatics platform for extended reproducible research.Q34284821
Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.Q34435174
Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathologyQ34749829
Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemiaQ35666277
ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cellsQ35853239
A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.Q36536303
Nuclear PTEN controls DNA repair and sensitivity to genotoxic stressQ37380066
Intrinsically disordered proteins: regulation and diseaseQ37868137
PTEN.Q38218236
Identification of intrinsically disordered regions in PTEN and delineation of its function via a network approachQ38275632
Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brainQ38340312
Differential proteomic analysis of mouse macrophages exposed to adsorbate-loaded heavy fuel oil derived combustion particles using an automated sample-preparation workflowQ38899787
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) has nuclear localization signal-like sequences for nuclear import mediated by major vault proteinQ40421181
Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt SignalingQ41728403
Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat modelQ43599319
Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.Q43662812
Nuclear trafficking of Pten after brain injury leads to neuron survival not death.Q43825562
ARC is a novel therapeutic approach against acetaminophen-induced hepatocellular necrosisQ43909890
Neuronal gelsolin prevents apoptosis by enhancing actin depolymerizationQ44764074
Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuriesQ46082313
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos diseaseQ47198022
Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injuryQ48244677
The signaling adapter, FRS2, facilitates neuronal branching in primary cortical neurons via both Grb2- and Shp2-dependent mechanismsQ48583456
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)3183
P577publication date2019-02-28
P1433published inScientific ReportsQ2261792
P1476titleUnique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress
P478volume9

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