Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice

scientific article

Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.4428-15.2016
P932PMC publication ID4971361
P698PubMed publication ID27488634

P50authorMatthias EndresQ15441092
Ulrich DirnaglQ27870042
Golo KronenbergQ41848355
Christoph HarmsQ42146749
Gisela TünnemannQ42832350
Ulrike HarmsQ45302001
Tracy D. FarrQ48714570
Ulrike GrittnerQ50554668
Martina FüchtemeierQ50639233
Anna Lena DatwylerQ50639574
Karen GertzQ56955221
Janet LipsQ56957366
René BernardQ57055511
Mustafa BalkayaQ114407341
P2093author name stringSusanne Müller
Marco Foddis
Gisela Lättig-Tünnemann
Anna Lena Datwyler
Junfeng An
Larissa Mosch
Sabrina Lin Lin Lee
Stefan Donath
P2860cites workTGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activationQ24291517
Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasmQ24291544
ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspasesQ24310176
Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activationQ24314624
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein DaxxQ24315012
Daxx, a Novel Fas-Binding Protein That Activates JNK and ApoptosisQ24316216
Cloning and expression of primate Daxx cDNAs and mapping of the human gene to chromosome 6p21.3 in the MHC regionQ28257276
The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemiaQ28281092
Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactionsQ28283531
Daxx: death or survival protein?Q28291053
Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinaseQ28298120
Distinguishing between exploratory and confirmatory preclinical research will improve translationQ28538978
Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21(Waf1/Cip1) as a novel mechanism of neuroprotection by glucocorticoidsQ28569805
Subcellular localization of Daxx determines its opposing functions in ischemic cell deathQ28570662
Blocking Daxx trafficking attenuates neuronal cell death following ischemia/reperfusion in rat hippocampus CA1 regionQ28572370
Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemiaQ28587245
Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stressQ29144910
Improving bioscience research reporting: the ARRIVE guidelines for reporting animal researchQ29547313
Future directions of acute ischaemic stroke therapyQ30970322
Intravenous TAT-GDNF is protective after focal cerebral ischemia in miceQ31137383
Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization.Q34229601
A critical role of neural-specific JNK3 for ischemic apoptosisQ34392478
Role of mitogen- and stress-activated kinases in ischemic injuryQ34667918
Histone acetylation and CREB binding protein are required for neuronal resistance against ischemic injuryQ35153024
SUMO2/3 conjugation is an endogenous neuroprotective mechanismQ35534157
Functions of MAP kinases: insights from gene-targeting studiesQ35814826
Physiological roles of SAPK/JNK signaling pathwayQ35924023
Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia.Q36340412
Role of alterations in the apoptotic machinery in sensitivity of cancer cells to treatmentQ36683578
Delayed inhibition of c-Jun N-terminal kinase worsens outcomes after focal cerebral ischemiaQ37117308
Number needed to treat to benefit and to harm for intravenous tissue plasminogen activator therapy in the 3- to 4.5-hour window: joint outcome table analysis of the ECASS 3 trialQ37300424
Apoptotic mechanisms after cerebral ischemiaQ37381350
Critical role for FoxO3a-dependent regulation of p21CIP1/WAF1 in response to statin signaling in cardiac myocytesQ38482275
Pharmacological therapy of acute ischaemic stroke: Achievements and problems.Q38529064
ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicityQ40010724
A kinase-independent function of Ask1 in caspase-independent cell deathQ40787647
Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.Q42828653
Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.Q43662812
ARC is a novel therapeutic approach against acetaminophen-induced hepatocellular necrosisQ43909890
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosisQ44485247
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemiaQ44560865
Neuronal gelsolin prevents apoptosis by enhancing actin depolymerizationQ44764074
TAT-Bcl-x(L) improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemiaQ44995916
The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathwaysQ45266708
Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathwayQ45270341
TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in miceQ46041604
Ways to measure body temperature in the fieldQ46596856
A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein DaxxQ46949438
Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acidQ48236376
Vascular signal transducer and activator of transcription-3 promotes angiogenesis and neuroplasticity long-term after strokeQ48270172
Neuroprotection by complement (C1) inhibitor in mouse transient brain ischemiaQ48394387
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.Q48455875
Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosisQ48555524
Neuroprotection against ischemic brain injury by a small peptide inhibitor of c-Jun N-terminal kinase (JNK) via nuclear and non-nuclear pathwaysQ48635445
TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure.Q52889320
Daxx is required for stress-induced cell death and JNK activation.Q53851366
Protein kinase CK2 links extracellular growth factor signaling with the control of p27Kip1 stability in the heartQ56973092
A microchip implant system as a method to determine body temperature of terminally ill rats and miceQ59700017
P4510describes a project that usesImageJQ1659584
P433issue31
P407language of work or nameEnglishQ1860
P921main subjectbrainQ1073
brain ischemiaQ4862390
P304page(s)8132-48
P577publication date2016-08-03
P1433published inJournal of NeuroscienceQ1709864
P1476titleInteraction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice
P478volume36

Reverse relations

cites work (P2860)
Q31161945Automated Ischemic Lesion Segmentation in MRI Mouse Brain Data after Transient Middle Cerebral Artery Occlusion
Q47973498Molecular basis for the effect of the L31F mutation on CARD function in ARC.
Q40120456Neuronal expression of the mitochondrial protein prohibitin confers profound neuroprotection in a mouse model of focal cerebral ischemia
Q37553811Neuroprotective effect of picroside II in brain injury in mice
Q44909378Stage 1 Registered Report: Effect of deficient phagocytosis on neuronal survival and neurological outcome after temporary middle cerebral artery occlusion (tMCAo).
Q89699235Tight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteins
Q64092698Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress