A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx

scientific article published on 15 October 2007

A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M704145200
P698PubMed publication ID17938171

P2093author name stringSam W Lee
Yih-Cherng Liou
Sheng-Cai Lin
Hisashi Hirano
Akihide Ryo
Ichiro Aoki
Kilian Perrem
Mayuko Nishi
Akiko Hirai
P2860cites workSequestration and inhibition of Daxx-mediated transcriptional repression by PMLQ22253162
Inhibition of Daxx-mediated apoptosis by heat shock protein 27Q24290301
The Hallmarks of CancerQ221226
Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APCQ24291638
Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activationQ24295079
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell deathQ24306270
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein DaxxQ24315012
Daxx, a Novel Fas-Binding Protein That Activates JNK and ApoptosisQ24316216
Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.Q24535558
Microtubule-targeting drugs induce bcl-2 phosphorylation and association with Pin1Q24551055
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insultsQ28210433
Pinning down proline-directed phosphorylation signalingQ28215887
Daxx: death or survival protein?Q28291053
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machineryQ28582080
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.Q33960826
Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.Q34285636
Advances in the biology of astrocytomasQ35948857
Targeted induction of apoptosis for cancer therapy: current progress and prospects.Q36517735
Role of alterations in the apoptotic machinery in sensitivity of cancer cells to treatmentQ36683578
Impairment of both apoptotic and cytoprotective signalings in glioma cells resistant to the combined use of cisplatin and tumor necrosis factor alphaQ38345776
Stable suppression of tumorigenicity by Pin1-targeted RNA interference in prostate cancerQ40358876
Pin1 links the activities of c-Abl and p300 in regulating p73 function.Q40549668
Tryptophan 621 and serine 667 residues of Daxx regulate its nuclear export during glucose deprivation.Q40558822
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).Q40920307
The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondriaQ43884355
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.Q44192183
Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancerQ44305041
Prolyl-isomerase Pin1 accumulates in lewy bodies of parkinson disease and facilitates formation of alpha-synuclein inclusionsQ46637747
An immunohistochemical scoring system of prolyl isomerase Pin1 for predicting relapse of prostate carcinoma after radical prostatectomyQ46974924
BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase.Q53633362
Daxx is required for stress-induced cell death and JNK activation.Q53851366
P433issue50
P407language of work or nameEnglishQ1860
P304page(s)36671-36681
P577publication date2007-10-15
P1433published inJournal of Biological ChemistryQ867727
P1476titleA suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx
P478volume282

Reverse relations

cites work (P2860)
Q34719741A distinct role for Pin1 in the induction and maintenance of pluripotency
Q37653100Berberine represses DAXX gene transcription and induces cancer cell apoptosis
Q92218177DAXX in cancer: phenomena, processes, mechanisms and regulation
Q24299167Daxx is reciprocally regulated by Mdm2 and Hausp
Q91650512Function of PIN1 in Cancer Development and Its Inhibitors as Cancer Therapeutics
Q39627492Functional involvement of Daxx in gp130-mediated cell growth and survival in BaF3 cells
Q59127766Gears-In-Motion: The Interplay of WW and PPIase Domains in Pin1
Q37469442Hyperthermia stress activates heat shock protein expression via propyl isomerase 1 regulation with heat shock factor 1.
Q37116300Immunohistochemical analysis of chromatin remodeler DAXX in high grade urothelial carcinoma
Q28595484Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice
Q38632886Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis
Q42152253Knockdown of Pin1 leads to reduced angiogenic potential and tumorigenicity in glioblastoma cells
Q33791759Mutant p53 disrupts the stress MAPK activation circuit induced by ASK1-dependent stabilization of Daxx
Q39423783Overexpression of peptidyl-prolyl isomerase Pin1 attenuates hepatocytes apoptosis and secondary necrosis following carbon tetrachloride-induced acute liver injury in mice
Q38680458PIN1 Modulates Huntingtin Levels and Aggregate Accumulation: An In vitro Model
Q37891181Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease
Q37433244Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process
Q33614048Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcription
Q37181702Pin1-Nanog expression in human glioma is correlated with advanced tumor progression
Q26825421Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins
Q27024695Prolyl isomerase Pin1 in cancer
Q53212676Prolyl isomerase Pin1 stabilizes and activates orphan nuclear receptor TR3 to promote mitogenesis.
Q58695611Prolyl isomerase Pin1: a promoter of cancer and a target for therapy
Q39741152Regulation of ICP0-null mutant herpes simplex virus type 1 infection by ND10 components ATRX and hDaxx
Q55208961The Clinical Implications of Death Domain-Associated Protein (DAXX) Expression.
Q57474469The Multiple Roles of Peptidyl Prolyl Isomerases in Brain Cancer
Q37355290The peptidyl-prolyl isomerase, Pin1, facilitates NF-kappaB binding in hepatocytes and protects against hepatic ischemia/reperfusion injury
Q39814307The prolyl isomerase Pin1 regulates the NF-kappaB signaling pathway and interleukin-8 expression in glioblastoma
Q37610703The role of PIN1 on odontogenic and adipogenic differentiation in human dental pulp stem cells.
Q38939954The role of Pin1 in the development and treatment of cancer
Q46297003Using global gene expression patterns to characterize Annexin V positive and negative human monocytes in culture

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