scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1046852045 |
P356 | DOI | 10.1038/SJ.ONC.1210175 |
P698 | PubMed publication ID | 17213812 |
P5875 | ResearchGate publication ID | 6587275 |
P2093 | author name string | P K Vogt | |
D L Durden | |||
C Prince | |||
G Denning | |||
B Jean-Joseph | |||
P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
PTEN function: how normal cells control it and tumour cells lose it | Q24528114 | ||
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway | Q24653458 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs | Q28564702 | ||
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway | Q28588309 | ||
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells | Q33586807 | ||
PTEN: a tumour suppressor that functions as a phospholipid phosphatase | Q33594251 | ||
Mutations of the human PTEN gene | Q33988995 | ||
Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane | Q34574432 | ||
Regulation of tumor suppressors by nuclear-cytoplasmic shuttling | Q35047240 | ||
Membrane-binding and activation mechanism of PTEN. | Q35145882 | ||
PTEN controls tumor-induced angiogenesis | Q35282160 | ||
Class reunion: PTEN joins the nuclear crew. | Q36313163 | ||
Regulation of PTEN function as a PIP3 gatekeeper through membrane interaction | Q36544446 | ||
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis | Q40372916 | ||
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) has nuclear localization signal-like sequences for nuclear import mediated by major vault protein | Q40421181 | ||
The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif | Q40601438 | ||
PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy | Q40765673 | ||
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation | Q42076186 | ||
PI 3-kinase, mTOR, protein synthesis and cancer | Q43786691 | ||
PTEN mutations in gliomas and glioneuronal tumors. | Q47995275 | ||
PTEN and p53: who will get the upper hand? | Q73086898 | ||
P433 | issue | 27 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell growth | Q189159 |
P304 | page(s) | 3930-3940 | |
P577 | publication date | 2007-01-08 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth | |
P478 | volume | 26 |
Q28546443 | A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity |
Q43268885 | A motor driving PTEN. |
Q38952567 | A new class of cancer-associated PTEN mutations defined by membrane translocation defects |
Q34921883 | A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localization |
Q52715838 | A pathogenic role for germline PTEN variants which accumulate into the nucleus. |
Q28305284 | A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. |
Q35201003 | A unified nomenclature and amino acid numbering for human PTEN. |
Q34722525 | AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor |
Q36851633 | ATP modulates PTEN subcellular localization in multiple cancer cell lines. |
Q26822064 | Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder |
Q38330271 | Characterization of nuclear PTEN and its post translational modifications |
Q34979031 | Controlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential. |
Q36724548 | Cytoplasmic PTEN protein loss distinguishes intraductal carcinoma of the prostate from high-grade prostatic intraepithelial neoplasia |
Q33895317 | Different conformations of phosphatase and tensin homolog, deleted on chromosome 10 (PTEN) protein within the nucleus and cytoplasm of neurons |
Q35166355 | Dissecting the cell to nucleus, perinucleus and cytosol. |
Q38275377 | Engineering PTEN function: membrane association and activity |
Q33854076 | Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities |
Q37381874 | Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity |
Q90481635 | FGD1 promotes tumor progression and regulates tumor immune response in osteosarcoma via inhibiting PTEN activity |
Q36006472 | Fine-Tuning of Pten Localization and Phosphatase Activity Is Essential for Zebrafish Angiogenesis |
Q26797287 | Focus on PTEN Regulation |
Q37252731 | Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function. |
Q90970814 | Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma |
Q26772947 | Inherited PTEN mutations and the prediction of phenotype |
Q35440540 | Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System. |
Q37351516 | Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells |
Q35057232 | Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium |
Q37018652 | Mechanisms of disease: the PI3K-Akt-PTEN signaling node--an intercept point for the control of angiogenesis in brain tumors |
Q35096583 | Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells |
Q36798747 | Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation |
Q92906114 | Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions |
Q24298305 | NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membrane |
Q34630287 | NOA36 protein contains a highly conserved nucleolar localization signal capable of directing functional proteins to the nucleolus, in mammalian cells |
Q53685190 | Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival. |
Q38652498 | Oncogenic PTEN functions and models in T-cell malignancies |
Q42117421 | Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN. |
Q34202681 | PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control |
Q38843254 | PTEN activation through K163 acetylation by inhibiting HDAC6 contributes to tumour inhibition |
Q38541293 | PTEN genomic deletion defines favorable prognostic biomarkers in localized prostate cancer: a systematic review and meta-analysis. |
Q28505099 | PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression |
Q49887901 | PTEN/PTENP1: 'Regulating the regulator of RTK-dependent PI3K/Akt signalling', new targets for cancer therapy. |
Q90429880 | PTEN: Tumor Suppressor and Metabolic Regulator |
Q40436436 | Phosphatase and Tensin Homolog Is a Growth Repressor of Both Rhizoid and Gametophore Development in the Moss Physcomitrella patens. |
Q64967349 | Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica. |
Q36998831 | Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis |
Q64114534 | Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology |
Q37628945 | RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors |
Q38259905 | Study of PTEN subcellular localization |
Q35971862 | The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis |
Q26776527 | The PTEN tumor suppressor gene and its role in lymphoma pathogenesis |
Q34828662 | The PTEN-PI3K pathway: of feedbacks and cross-talks |
Q37292760 | The insulin receptor substrate-1: a biomarker for cancer? |
Q94475216 | miR-19 promotes development of renal fibrosis by targeting PTEN-mediated epithelial-mesenchymal transition |
Q37188735 | ΔNp63α represses nuclear translocation of PTEN by inhibition of NEDD4-1 in keratinocytes |
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