Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica.

scientific article published on 6 June 2019

Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3389/FCIMB.2019.00150
P932PMC publication ID6563779
P698PubMed publication ID31245297

P50authorKumiko Nakada-TsukuiQ66018122
Tomoyoshi NozakiQ90252123
P2093author name stringTomohiko Maehama
Natsuki Watanabe
P2860cites workGlobal and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010Q21534928
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Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphateQ22254632
Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth diseaseQ24291963
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...Q24292896
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIαQ24292907
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTENQ24292919
Ubiquitination regulates PTEN nuclear import and tumor suppressionQ24292946
SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formationQ24293490
NRBF2 regulates macroautophagy as a component of Vps34 Complex IQ24296638
PIKfyve Controls Fluid Phase Endocytosis but Not Recycling/Degradation of Endocytosed Receptors or Sorting of Procathepsin D by Regulating Multivesicular Body MorphogenesisQ24297560
NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activityQ24298024
PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.Q45904675
Entamoeba histolytica under Oxidative Stress: What Countermeasure Mechanisms Are in Place?Q46257151
Phosphoinositide Diversity, Distribution, and Effector Function: Stepping Out of the Box.Q46294972
The diversity of Rab GTPases in Entamoeba histolyticaQ46546068
Chemotaxis of Entamoeba histolytica towards the pro-inflammatory cytokine TNF is based on PI3K signalling, cytoskeleton reorganization and the Galactose/N-acetylgalactosamine lectin activityQ46639155
Application of micro-CT assessment of 3-D bone microstructure in preclinical and clinical studiesQ46776300
Entamoeba histolytica: FYVE-finger domains, phosphatidylinositol 3-phosphate biosensors, associate with phagosomes but not fluid filled endosomesQ46874744
Systematic analysis of myotubularins: heteromeric interactions, subcellular localisation and endosome related functionsQ47037344
The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.Q47068786
PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.Q47100426
Identification of the Interactome of a Palmitoylated Membrane Protein, Phosphatidylinositol 4-Kinase Type II Alpha.Q47131018
Identification of the Binding Sites on Rab5 and p110beta Phosphatidylinositol 3-kinaseQ47137200
Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformationQ47273443
PtdIns3P controls mTORC1 signaling through lysosomal positioning.Q47655222
Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineageQ47669002
Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancersQ47814180
Uniqueness of Entamoeba sulfur metabolism: sulfolipid metabolism that plays pleiotropic roles in the parasitic life cycleQ47836327
Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid.Q48139459
TMEM55a localizes to macrophage phagosomes to down-regulate phagocytosisQ48147753
EhRho1 regulates plasma membrane blebbing through PI3 kinase in Entamoeba histolyticaQ48182332
Nutrient sensing in the mTOR/S6K1 signalling pathwayQ48235664
Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancersQ48464018
Early steps along the road to inositol-lipid-based signallingQ48886972
Phosphoinositide conversion in endocytosis and the endolysosomal systemQ49547382
Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylationQ50335975
Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatasesQ24298042
ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sitesQ24298628
Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphataseQ24299014
The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatasesQ24299329
Human VPS34 and p150 are Rab7 Interacting PartnersQ24299781
Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L).Q24300421
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.Q24301637
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1Q24302530
Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase ItchQ24303654
Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complexQ24307982
Characterization of a cDNA encoding the 43-kDa membrane-associated inositol-polyphosphate 5-phosphataseQ24311855
Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9Q24313006
Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscleQ24313412
PI(5)P regulates autophagosome biogenesisQ24313624
Properties of type II inositol polyphosphate 5-phosphataseQ24314934
Lowe syndrome protein OCRL1 interacts with Rac GTPase in the trans-Golgi networkQ24314940
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAsQ24315942
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
The Isolation and Characterization of cDNA Encoding Human and Rat Brain Inositol Polyphosphate 4-PhosphataseQ24318660
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouseQ24318746
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stagesQ24318814
Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15Q24320037
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
The cloning and sequence of the C isoform of PtdIns4P 5-kinaseQ24322823
INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouseQ24323384
MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae.Q27939032
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiaeQ27940050
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sortingQ27940116
Targeting Plasmodium PI(4)K to eliminate malariaQ27974482
Emerging roles of PtdIns(4,5)P2--beyond the plasma membraneQ28084524
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinaseQ28115936
Identification and characterization of a sac domain-containing phosphoinositide 5-phosphataseQ28117024
Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathwayQ28117913
The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphataseQ28118769
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identityQ28118990
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formationQ28139699
A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cellsQ28140807
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanismsQ28181035
Allosteric activation of PTEN phosphatase by phosphatidylinositol 4,5-bisphosphateQ28186818
Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalizationQ28189193
Myotubularins, a large disease-associated family of cooperating catalytically active and inactive phosphoinositides phosphatasesQ28202357
Human RhoGAP domain-containing proteins: structure, function and evolutionary relationshipsQ28203687
The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane traffickingQ28203805
A novel family of phosphatidylinositol 4-kinases conserved from yeast to humansQ28204394
Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminalsQ28212156
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talinQ28214335
Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesionsQ28214350
Nuclear localization of phosphatidylinositol 4-kinase betaQ28214594
Inositol polyphosphate 4-phosphatase is inactivated by calpain-mediated proteolysis in stimulated human plateletsQ28235484
Phosphatidylinositol 4-kinasebeta is critical for functional association of rab11 with the Golgi complexQ28242748
Lowe syndrome protein Ocrl1 is translocated to membrane ruffles upon Rac GTPase activation: a new perspective on Lowe syndrome pathophysiologyQ28245047
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphateQ28254402
Phospho-specific binding of 14-3-3 proteins to phosphatidylinositol 4-kinase III beta protects from dephosphorylation and stabilizes lipid kinase activityQ28258031
The phosphatidylinositol 4-kinases: don't call it a comebackQ28261463
Protein kinase C: poised to signalQ28265620
Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulationQ28266081
The SH2-containing inositol polyphosphate 5-phosphatase, ship, is expressed during hematopoiesis and spermatogenesisQ28266777
Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase familyQ28267069
Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndromeQ28268735
Phospholipase D: a lipid centric reviewQ28270831
The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyondQ28278349
Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphateQ28280837
Viral reorganization of the secretory pathway generates distinct organelles for RNA replicationQ28283814
Protein kinase C and lipid signaling for sustained cellular responsesQ28300819
Cinderella story: PI4P goes from precursor to key signaling moleculeQ28301748
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersQ28306997
Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cellsQ28344470
TPIP: a novel phosphoinositide 3-phosphataseQ28364566
Novel transmembrane receptor involved in phagosome transport of lysozymes and β-hexosaminidase in the enteric protozoan Entamoeba histolyticaQ28481193
Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesisQ28505080
Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesisQ28506609
Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brainQ28506799
A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gammaQ28508645
Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activityQ28508698
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphateQ28511509
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4JQ28511673
Essential role of phosphoinositide metabolism in synaptic vesicle recyclingQ28511682
Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi networkQ28512973
Essential role for nuclear PTEN in maintaining chromosomal integrityQ28513781
A presynaptic inositol-5-phosphataseQ28565411
Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complexQ28567098
Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activityQ28567201
A novel phosphatidylinositol-5-phosphate 4-kinase (phosphatidylinositol-phosphate kinase IIgamma) is phosphorylated in the endoplasmic reticulum in response to mitogenic signalsQ28579260
Novel inositol polyphosphate 5-phosphatase localizes at membrane rufflesQ28581567
The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.Q28583817
Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathwaysQ28586271
Distinct membrane and cytosolic forms of inositol polyphosphate 5-phosphatase II. Efficient membrane localization requires two discrete domainsQ28586743
Delayed reentry of recycling vesicles into the fusion-competent synaptic vesicle pool in synaptojanin 1 knockout miceQ28590195
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesityQ28590308
Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life spanQ28590421
Characterization of the murine Inpp4b gene and identification of a novel isoformQ28590569
Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1Q28592644
A Phosphoinositide Code for Primary Cilia.Q50568217
RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium.Q50771615
Fatty-acyl chain profiles of cellular phosphoinositides.Q50897979
Src and PI3 K inhibitors affect the virulence factors of Entamoeba histolytica.Q51756407
Rab11B small GTPase regulates secretion of cysteine proteases in the enteric protozoan parasite Entamoeba histolytica.Q51798147
The effect of missense mutations in the RhoGAP-homology domain on ocrl1 function.Q51915970
Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output.Q52151849
EhRho1 regulates phagocytosis by modulating actin dynamics through EhFormin1 and EhProfilin1 in Entamoeba histolytica.Q52583752
Sending mixed signals: Cilia-dependent signaling during development and disease.Q52726088
Frequency distribution of Entamoeba histolytica zymodemes in a rural South African population.Q53901728
Structural and membrane binding analysis of the Phox homology domain of phosphoinositide 3-kinase-C2alpha.Q54453781
Identification, Characterization and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria.Q54976556
Non-vesicular Lipid Transport Machinery inQ57072550
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1Q57184595
PTEN Autoregulates Its Expression by Stabilization of p53 in a Phosphatase-Independent MannerQ57591077
Regulation of Fc R-stimulated phagocytosis by the 72-kDa inositol polyphosphate 5-phosphatase: SHIP1, but not the 72-kDa 5-phosphatase, regulates complement receptor 3 mediated phagocytosis by differential recruitment of these 5-phosphatases to the pQ63681815
Purification and kinetic properties of a membrane-bound phosphatidylinositol kinase of the bovine adrenal medullaQ68449879
Effect of inositol-1,4,5-trisphosphate on isolated subcellular fractions of rat pancreasQ70228815
Relative importance of inositol (1,4,5)trisphosphate and inositol (1,3,4,5)tetrakisphosphate in Entamoeba histolyticaQ71525167
Inositol(1,3,4,5) tetrakisphosphate plays an important role in calcium mobilization from Entamoeba histolyticaQ72189242
Myo-inositol trisphosphate-mediated calcium release from internal stores of Entamoeba histolyticaQ72741131
Purification and characterization of a 43-kDa membrane-associated inositol polyphosphate 5-phosphatase from human placentaQ72954285
The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptorQ73343323
The activation loop of phosphatidylinositol phosphate kinases determines signaling specificityQ73456411
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignanciesQ73722520
Stereo-specific substrate recognition by phosphatidylinositol phosphate kinases is swapped by changing a single amino acid residueQ77322068
Biochemical characterization of the type I inositol polyphosphate 4-phosphatase C2 domainQ79915287
PtdIns(4,5)P2 is generated by a novel phosphatidylinositol 4-phosphate 5-kinase in the protist parasite Entamoeba histolyticaQ92184752
Inositol and its derivatives: Their evolution and functionsQ37808779
INPP4A/INPP4B and P-Rex proteins: related but different?Q37933865
Structural basis for activation and inhibition of class I phosphoinositide 3-kinasesQ37947094
Myotubularin phosphoinositide phosphatases: cellular functions and disease pathophysiologyQ38009455
Phosphatidylinositol-4-phosphate: the Golgi and beyondQ38109881
Ca2+ signalling early in evolution--all but primitiveQ38111343
Inositol 1,4,5-trisphosphate induces calcium release from sarcoplasmic reticulum of skeletal muscleQ38150979
Nuclear phosphoinositides and their impact on nuclear functionsQ38151274
Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics.Q38174542
Inositol lipid phosphatases in membrane trafficking and human disease.Q38223317
Phosphoinositides and engulfmentQ38235130
New insight into the intracellular roles of class II phosphoinositide 3-kinases.Q38252290
Protein kinase C involvement in cell cycle modulationQ38252322
PI(4,5)P₂-binding effector proteins for vesicle exocytosisQ38256514
The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional outputQ38299829
Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discoveryQ38503780
Phosphatidylinositol 4-phosphate 5-kinase Iγ_v6, a new splice variant found in rodents and humansQ38531376
Nuclear Phosphatidylinositol Signaling: Focus on Phosphatidylinositol Phosphate Kinases and Phospholipases C.Q38655657
Entamoeba thiol-based redox metabolism: A potential target for drug developmentQ38699123
Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fissionQ38719619
PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment.Q38746550
The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processingQ38764137
Rab35 GTPase: A Central Regulator of Phosphoinositides and F-actin in Endocytic Recycling and Beyond.Q38872611
Phosphoinositides in Control of Membrane DynamicsQ38941267
Structure and content of the Entamoeba histolytica genomeQ38947857
Emerging themes of regulation at the Golgi.Q38954641
PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages.Q38973926
PI4K2β/AP-1-based TGN-endosomal sorting regulates Wnt signalingQ39065561
Quantifying lipid changes in various membrane compartments using lipid binding protein domainsQ39088749
K562 cell proliferation is modulated by PLCβ1 through a PKCα-mediated pathwayQ39154752
Nuclear phosphoinositide regulation of chromatin.Q39159757
PI5P and PI(3,5)P2: Minor, but Essential Phosphoinositides.Q39182894
Inhibition of encystation of Entamoeba invadens by wortmanninQ39206895
Recent progress in autophagic lysosome reformationQ39216333
A novel spliced form of SH2-containing inositol phosphatase is expressed during myeloid developmentQ28594494
Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activationQ28616026
The TPTE gene family: cellular expression, subcellular localization and alternative splicingQ28678657
Biochemistry and evolution of anaerobic energy metabolism in eukaryotesQ28728648
Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatasesQ29248612
The primary cilium: a signalling centre during vertebrate developmentQ29547197
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolismQ29547302
The role of Atg proteins in autophagosome formationQ29547418
Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular bodyQ29547922
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAGQ29614477
The emerging mechanisms of isoform-specific PI3K signallingQ29617954
The role of protein kinase C in cell surface signal transduction and tumour promotionQ29618532
Termination of autophagy and reformation of lysosomes regulated by mTORQ29619817
Dap160, a neural-specific Eps15 homology and multiple SH3 domain-containing protein that interacts with Drosophila dynaminQ30176122
Amphiphysin I is associated with coated endocytic intermediates and undergoes stimulation-dependent dephosphorylation in nerve terminalsQ30176331
Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filamentsQ30176495
Identification of Entamoeba histolytica thiol-specific antioxidant as a GalNAc lectin-associated proteinQ30310731
PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7.Q30360337
A phylogenetic survey of myotubularin genes of eukaryotes: distribution, protein structure, evolution, and gene expressionQ30390703
Etiology of diarrhea in Bangladeshi infants in the first year of life analyzed using molecular methodsQ30409328
Trogocytosis by Entamoeba histolytica contributes to cell killing and tissue invasionQ30409977
A genomewide overexpression screen identifies genes involved in the phosphatidylinositol 3-kinase pathway in the human protozoan parasite Entamoeba histolyticaQ30410980
Cysteine protease-binding protein family 6 mediates the trafficking of amylases to phagosomes in the enteric protozoan Entamoeba histolyticaQ30416566
Exposure to host ligands correlates with colocalization of Gal/GalNAc lectin subunits in lipid rafts and phosphatidylinositol (4,5)-bisphosphate signaling in Entamoeba histolyticaQ30423642
Localisation to lipid rafts correlates with increased function of the Gal/GalNAc lectin in the human protozoan parasite, Entamoeba histolyticaQ30424011
A novel class of cysteine protease receptors that mediate lysosomal transportQ30424581
Localization of phosphatidylinositol (3,4,5)-trisphosphate to phagosomes in entamoeba histolytica achieved using glutathione S-transferase- and green fluorescent protein-tagged lipid biosensorsQ30435663
Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxisQ30443781
Regulation of virulence of Entamoeba histolyticaQ30458548
Phospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxisQ30480754
Phosphatidylinositol-3-OH kinases are Rab5 effectors.Q30638959
Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosisQ30834311
The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysisQ30912298
Regulation of mTORC1 by PI3K signalingQ26995791
Phosphoinositides: tiny lipids with giant impact on cell regulationQ27012953
The role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migrationQ27021287
PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes.Q27305167
Mechanism of enzymatic reaction and protein-protein interactions of PLD from a 3D structural modelQ27321589
Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 proteinQ27325539
Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranesQ27330350
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane associationQ27620298
Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndromeQ27642841
Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase functionQ27660521
Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and SodiumQ27674638
Structures of PI4KIII  complexes show simultaneous recruitment of Rab11 and its effectorsQ27684007
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
Phosphoinositides in cell regulation and membrane dynamicsQ27861051
Suppressors of yeast actin mutationsQ27929812
PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus.Q27930562
Membrane association and functional regulation of Sec3 by phospholipids and Cdc42Q27930739
Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1pQ27930743
Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasisQ27931112
Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipidsQ27931171
Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular bodyQ27932192
Vacuole Size Control: Regulation of PtdIns(3,5)P2Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P2-specific PhosphataseQ27933521
Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membraneQ27933752
SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatasesQ27934132
Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifsQ27934845
Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesisQ27935369
Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3.Q27936084
Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sitesQ27937449
Membrane lipid composition protects Entamoeba histolytica from self-destruction by its pore-forming toxinsQ33201893
The role of phosphatases in inositol signaling reactionsQ33589780
PTEN: a tumour suppressor that functions as a phospholipid phosphataseQ33594251
Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brainQ33621547
Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum.Q33636764
PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium functionQ33701751
InsP3 Signaling in Apicomplexan ParasitesQ33850811
Phosphoinositide signaling and the regulation of membrane trafficking in yeastQ33899382
Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesiclesQ33911122
Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolyticaQ33917464
Identification of four candidate cGMP targets in DictyosteliumQ34067409
The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamicsQ34069966
A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in DictyosteliumQ34090804
A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolyticaQ34099558
Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIalpha and IIbeta and a partial nuclear localization of the IIalpha isoformQ34146977
Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretionQ34168003
Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- miceQ34182057
PI3K: from the bench to the clinic and backQ34195495
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptorQ34214128
Amoebic PI3K and PKC is required for Jurkat T cell death induced by Entamoeba histolyticaQ34218841
Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the GolgiQ34221739
Phosphatidylinositol Phosphate Kinases Put PI4,5P 2 in Its PlaceQ34264164
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphateQ34264314
Prevalent and incident HIV diagnoses among Entamoeba histolytica-infected adult males: a changing epidemiology associated with sexual transmission--Taiwan, 2006-2013.Q34315165
The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinasesQ34318366
Rubicon controls endosome maturation as a Rab7 effectorQ34320360
Cloning and expression of human brain type I inositol 1,4,5-trisphosphate 5-phosphatase. High levels of mRNA in cerebellar Purkinje cellsQ34328974
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunitsQ34339415
Tissue distribution and intracellular localisation of the 75-kDa inositol polyphosphate 5-phosphatase.Q34367979
Class IA phosphatidylinositol 3-kinase p110α regulates phagosome maturationQ34395900
The phosphatidylinositol 4-phosphate 5-kinase family.Q34402664
Signalling roles of mammalian phospholipase D1 and D2.Q34437828
The identification of pats1, a novel gene locus required for cytokinesis in Dictyostelium discoideumQ34450548
Specificity of activation by phosphoinositides determines lipid regulation of Kir channelsQ34470673
Phosphatidylinositol 4-kinase is required for endosomal trafficking and degradation of the EGF receptorQ34489231
Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levelsQ34512579
Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4KbetaQ34562857
Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasitesQ34601985
Coordination of Golgi functions by phosphatidylinositol 4-kinasesQ34644921
The direct interaction between ASH2, a Drosophila trithorax group protein, and SKTL, a nuclear phosphatidylinositol 4-phosphate 5-kinase, implies a role for phosphatidylinositol 4,5-bisphosphate in maintaining transcriptionally active chromatinQ34645506
Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosisQ34701557
Inositol derivatives: evolution and functionsQ34740418
Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90Q34752697
Mammalian phosphoinositide kinases and phosphatasesQ34990891
Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.Q35005794
Highly divergent mitochondrion-related organelles in anaerobic parasitic protozoaQ35062256
Nuclear lipid signallingQ35120151
Mammalian Phosphatidylinositol 4‐KinasesQ35128554
The molecular machinery of synaptic vesicle exocytosisQ35162998
Phosphoinositides regulate ion channels.Q35192402
The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysisQ35225936
Polyphosphoinositide binding domains: Key to inositol lipid biology.Q35236004
Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesisQ35484919
Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathwayQ35503921
Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistanceQ35569960
Protein Targeting to Endosomes and Phagosomes via FYVE and PX DomainsQ35573989
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signalingQ35642868
The oculocerebrorenal syndrome gene product is a 105-kD protein localized to the Golgi complexQ35644500
Phosphoregulatory protein 14-3-3 facilitates SAC1 transport from the endoplasmic reticulumQ35796202
The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradationQ35814123
The phospholipase D1 pathway modulates macroautophagyQ35894139
A role for phosphoinositides in regulating plant nuclear functionsQ35970847
Axl receptor tyrosine kinase is up-regulated in metformin resistant prostate cancer cellsQ36021012
Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8.Q36066328
Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodelingQ36091837
Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1.Q36127992
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin functionQ36222030
Structure and function of the Lowe syndrome protein OCRL1.Q36230674
Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2Q24336573
The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphataseQ24336782
PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complexQ24337031
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent mannerQ24337323
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repressionQ24338124
Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.Q24515262
The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membraneQ24523405
Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositidesQ24529828
Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi networkQ24534275
Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphataseQ24538782
Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activityQ24551012
Animals and fungi are each other's closest relatives: congruent evidence from multiple proteinsQ24563729
A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathwayQ24569564
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cellsQ24599234
In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.Q24617439
Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeastQ24619173
E3 ligase Nedd4 promotes axon branching by downregulating PTENQ24630190
Interaction of the type Ialpha PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4, 5-bisphosphate in the regulation of PLD2 activityQ24631166
Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome proteinQ24642969
Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphataseQ24643186
Differential clathrin binding and subcellular localization of OCRL1 splice isoformsQ24647288
Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathiesQ24651557
The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domainQ24653611
Stimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2mu-cargo complexesQ24671026
Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca(2+) signalingQ24676005
Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.Q24678783
Mergers and acquisitions: malaria and the great chloroplast heistQ24804750
Skeletal Muscle Pathology in X-Linked Myotubular Myopathy: Review With Cross-Species ComparisonsQ26773024
The Exocyst at a GlanceQ26799386
Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesQ26823331
Metabolism and possible compartmentalization of inositol lipids in isolated rat-liver nucleiQ42988221
Nuclear targeting of the beta isoform of type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its alpha-helix 7.Q42996043
Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.Q43129377
PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.Q43247716
Phosphatidylinositol 4,5-bisphosphate mediates Ca2+-induced platelet alpha-granule secretion: evidence for type II phosphatidylinositol 5-phosphate 4-kinase functionQ43576545
Mechanism of ADP ribosylation factor-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cellsQ43823955
Phosphatidylinositol-phosphates mediate cytoskeletal reorganization during phagocytosis via a unique modular protein consisting of RhoGEF/DH and FYVE domains in the parasitic protozoon Entamoeba histolyticaQ43833178
PTEN controls immunoreceptor (immunoreceptor tyrosine-based activation motif) signaling and the activation of Rac.Q43847751
Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruziQ44896476
The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulationQ36310121
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathwayQ36320962
Plasma membrane of Entamoeba histolyticaQ36343964
A regulatory role for Src homology 2 domain-containing inositol 5'-phosphatase (SHIP) in phagocytosis mediated by Fc gamma receptors and complement receptor 3 (alpha(M)beta(2); CD11b/CD18)Q36376113
Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1.Q36492075
Regulation of nuclear processes by inositol polyphosphatesQ36510091
Role of phosphoinositides at the neuronal synapseQ36528090
Myotubularin phosphatases: policing 3-phosphoinositidesQ36530570
Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movementQ36639138
Multiple Cytokines Stimulate the Binding of a Common 145-Kilodalton Protein to Shc at the Grb2 Recognition Site of ShcQ36668147
Phosphatidylinositol 3-phosphates-at the interface between cell signalling and membrane traffic.Q36712621
The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3'-end of mRNAsQ36765062
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiaeQ36775602
Phosphatidylinositol 3,5-bisphosphate: regulation of cellular events in space and timeQ36812142
Cancer-specific mutations in phosphatidylinositol 3-kinaseQ36846595
Epidemiology of Domestically Acquired Amebiasis in Japan, 2000-2013.Q36869493
Localization of phosphatidylinositol 4,5-bisphosphate to lipid rafts and uroids in the human protozoan parasite Entamoeba histolyticaQ36911466
PTEN: its deregulation and tumorigenesis.Q36935178
Lipid signaling and the modulation of surface charge during phagocytosisQ36938589
Nuclear phosphoinositide signalingQ36991854
Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damageQ36994748
The multiple roles of PtdIns(4)P -- not just the precursor of PtdIns(4,5)P2.Q37182226
The deficiency of PIP2 5-phosphatase in Lowe syndrome affects actin polymerizationQ37204230
Structural insights into the centronuclear myopathy-associated functions of BIN1 and dynamin 2.Q37289753
The function of ROCO proteins in health and disease.Q37371868
Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targetingQ37434355
The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrinQ37534739
The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic.Q37573365
Classes of phosphoinositide 3-kinases at a glanceQ37608715
Localization, regulation and function of type II phosphatidylinositol 5-phosphate 4-kinasesQ37629206
Conservation and function of Rab small GTPases in Entamoeba: annotation of E. invadens Rab and its use for the understanding of Entamoeba biologyQ37740421
Non-vesicular lipid transport by lipid-transfer proteins and beyondQ37786206
Problems in recognition and diagnosis of amebiasis: estimation of the global magnitude of morbidity and mortalityQ39439493
The metabolism of phosphoinositide-derived messenger molecules.Q39506001
Autophagosome-lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome.Q39658143
Inositol trisphosphate and diacylglycerol: two interacting second messengersQ39664919
PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4KalphaQ39687546
Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy.Q39802205
Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephronQ39946401
PI(3,4,5)P3 and PI(3,4)P2 levels correlate with PKB/akt phosphorylation at Thr308 and Ser473, respectively; PI(3,4)P2 levels determine PKB activity.Q40016674
Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate.Q40020862
The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questionsQ40086486
Inositol trisphosphate and diacylglycerol as second messengersQ40094697
AGC family kinase 1 participates in trogocytosis but not in phagocytosis in Entamoeba histolyticaQ40121521
Monocyte p110alpha phosphatidylinositol 3-kinase regulates phagocytosis, the phagocyte oxidase, and cytokine productionQ40157289
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.Q40178894
A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growthQ40184782
Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression.Q40198370
Phosphatidylinositol 4-phosphate formation at ER exit sites regulates ER exportQ40212158
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor functionQ40250486
The p110delta isoform of PI3K differentially regulates beta1 and beta2 integrin-mediated monocyte adhesion and spreading and modulates diapedesisQ40252002
The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulationQ40254270
p53 down-regulates phosphatase and tensin homologue deleted on chromosome 10 protein stability partially through caspase-mediated degradation in cells with proteasome dysfunctionQ40267012
Individual phosphoinositide 3-kinase C2alpha domain activities independently regulate clathrin functionQ40363752
Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosisQ40372916
SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survivalQ40443155
BFA-sensitive and insensitive exocytic pathways in Entamoeba histolytica trophozoites: their relationship to pathogenesisQ40612408
Overexpression of murine phosphatidylinositol 4-phosphate 5-kinase type Ibeta disrupts a phosphatidylinositol 4,5 bisphosphate regulated endosomal pathwayQ40744922
mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survivalQ40771740
Phosphatidylinositol-4-phosphate 5-kinase-1beta is essential for epidermal growth factor receptor-mediated endocytosisQ40777500
Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter proteinQ40778927
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathwayQ40789651
Association of phosphatidylinositol 3-kinase composed of p110beta-catalytic and p85-regulatory subunits with the small GTPase Rab5.Q40795602
PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signallingQ40810931
Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathwayQ40852967
A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuoleQ40872969
Ocrl1, a PtdIns(4,5)P(2) 5-phosphatase, is localized to the trans-Golgi network of fibroblasts and epithelial cellsQ40905503
LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in miceQ40988812
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cellsQ40993616
The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregationQ41151188
Humoral immune responses of lung cancer patients against the Transmembrane Phosphatase with TEnsin homology (TPTE).Q41389224
The inositol phosphatase SHIP-2 down-regulates FcgammaR-mediated phagocytosis in murine macrophages independently of SHIP-1.Q41902860
Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositolQ42060774
Identification of the major synaptojanin-binding proteins in brainQ42062585
Nucleocytoplasmic shuttling of the Golgi phosphatidylinositol 4-kinase Pik1 is regulated by 14-3-3 proteins and coordinates Golgi function with cell growthQ42064643
Direct modification and activation of a nuclear receptor-PIP₂ complex by the inositol lipid kinase IPMK.Q42077086
Relationship between phosphatidylinositol synthesis and recovery of 5-hydroxytryptamine-responsive Ca2+ flux in blowfly salivary glandsQ42152335
Ligand heterogeneity of the cysteine protease binding protein family in the parasitic protist Entamoeba histolyticaQ42211630
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog SignalingQ42287159
Phosphatidylinositol 4,5-bisphosphate reverses the inhibition of RNA transcription caused by histone H1.Q42451859
Interaction of neuronal calcium sensor-1 (NCS-1) with phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and affects membrane trafficking in COS-7 cellsQ42509322
Regulation of cardiac Na+,Ca2+ exchange and KATP potassium channels by PIP2.Q42555612
Targeting of the type II inositol polyphosphate 5-phosphatase INPP5B to the early secretory pathwayQ42635381
Phosphatidylinositol 4-kinase type IIalpha is targeted specifically to cellugyrin-positive glucose transporter 4 vesicles.Q42800351
Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma.Q42815905
Evidence that a phosphatidylinositol 3,4,5-trisphosphate-binding protein can function in nucleusQ42819910
A differential location of phosphoinositide kinases, diacylglycerol kinase, and phospholipase C in the nuclear matrixQ42822913
Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha.Q42825155
Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones.Q42867655
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectEntamoeba histolyticaQ131027
P304page(s)150
P577publication date2019-06-06
P1433published inFrontiers in Cellular and Infection MicrobiologyQ27724376
P1476titlePhosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica.
P478volume9

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