PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.

scientific article published on 16 February 2006

PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.EMBOJ.7601001
P8608Fatcat IDrelease_fu52kcpohnagpmlaxqeqfgpkxq
P932PMC publication ID1409730
P698PubMed publication ID16482216
P5875ResearchGate publication ID7295203

P50authorOr GozaniQ28324720
Fréderique Gaits-IacovoniQ54525193
P2093author name stringPhilippe J Sansonetti
Hélène Tronchère
Bernard Payrastre
Laurence Arbibe
Michael J Fry
Caroline Pendaries
Lewis Cantley
Joelle Mounier
P2860cites workPhosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatasesQ24298042
Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphologyQ24534908
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cellsQ24599234
The phosphoinositide 3-kinase pathwayQ27860738
NMR structure of the amino-terminal domain from the Tfb1 subunit of TFIIH and characterization of its phosphoinositide and VP16 binding sitesQ27934392
Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesionQ27939824
Allosteric activation of PTEN phosphatase by phosphatidylinositol 4,5-bisphosphateQ28186818
The Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cellsQ28188461
Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cellsQ28203466
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphateQ28254402
Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaBQ28289989
SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphataseQ28369269
The TOR pathway: a target for cancer therapyQ29614242
Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangementQ30160287
A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host cell actin cytoskeleton rearrangements and bacterial internalizationQ31795453
Molecular bases of epithelial cell invasion by Shigella flexneriQ33542385
Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathwaysQ33545062
Characterization of the Shigella flexneri ipgD and ipgF genes, which are located in the proximal part of the mxi locusQ33594863
Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in miceQ33860786
Thrombin stimulation of platelets causes an increase in phosphatidylinositol 5-phosphate revealed by mass assayQ33905722
Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporterQ34036123
Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- miceQ34182057
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptorQ34214128
Phosphoinositides: key players in cell signalling, in time and space.Q34268796
Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cellsQ34281754
Bacterial invasion: the paradigms of enteroinvasive pathogensQ34312229
Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocationQ34337320
The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt.Q34383320
The activation of Akt/PKB signaling pathway and cell survival.Q34405519
Effects of lipid kinase expression and cellular stimuli on phosphatidylinositol 5-phosphate levels in mammalian cell linesQ34416355
Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphataseQ34612727
Phosphoinositide signaling disorders in human diseasesQ35163916
Lipid Signalling: Picking Out The PIPsQ35560827
PI-loting membrane trafficQ35788132
The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradationQ35814123
Cytoskeletal regulation: rich in lipidsQ35887301
Subversion of phosphoinositide metabolism by intracellular bacterial pathogensQ35934194
Tyrosine kinase signaling and type III effectors orchestrating Shigella invasionQ36032345
Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.Q36321148
Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cellsQ36382504
Induction of anti-carbohydrate antibodies by phage library-selected peptide mimicsQ36890938
Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysisQ37056339
Activation of Akt/protein kinase B in epithelial cells by the Salmonella typhimurium effector sigD.Q38308519
Host/pathogen interactions. Subversion of the mammalian cell cytoskeleton by invasive bacteriaQ39784118
Cross-talk between bacterial pathogens and their host cellsQ41275240
Shigella flexneri induces apoptosis in infected macrophagesQ41614246
IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cellsQ42206130
A synaptojanin-homologous region of Salmonella typhimurium SigD is essential for inositol phosphatase activity and Akt activationQ43580834
Emerging roles of phosphatidylinositol monophosphates in cellular signaling and traffickingQ46603958
Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by SalmonellaQ50107182
IpgD, a protein secreted by the type III secretion machinery of Shigella flexneri, is chaperoned by IpgE and implicated in entry focus formationQ73072694
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectShigella flexneriQ1644417
P304page(s)1024-1034
P577publication date2006-02-16
P1433published inThe EMBO JournalQ1278554
P1476titlePtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection
P478volume25

Reverse relations

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