| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2016PLoSO..1154771S |
| P356 | DOI | 10.1371/JOURNAL.PONE.0154771 |
| P932 | PMC publication ID | 4854392 |
| P698 | PubMed publication ID | 27138341 |
| P2093 | author name string | Jeroen den Hertog | |
| Sasja Blokzijl-Franke | |||
| Miriam Stumpf | |||
| P2860 | cites work | Phosphorylation of the PTEN tail regulates protein stability and function | Q22254305 |
| The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation | Q24290417 | ||
| Ubiquitination regulates PTEN nuclear import and tumor suppression | Q24292946 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
| Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner | Q24337323 | ||
| Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association | Q27620298 | ||
| Stages of embryonic development of the zebrafish | Q27860947 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity | Q28269344 | ||
| A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. | Q28305284 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Essential role for nuclear PTEN in maintaining chromosomal integrity | Q28513781 | ||
| A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity | Q28546443 | ||
| Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs | Q28564702 | ||
| PTEN mediates Notch-dependent stalk cell arrest in angiogenesis | Q33663049 | ||
| Expression from DNA injected into Xenopus embryos | Q33741808 | ||
| Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities | Q33854076 | ||
| Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex | Q34101673 | ||
| Angiogenesis in ischemic and neoplastic disorders | Q34931041 | ||
| Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium | Q35057232 | ||
| Arteries, veins, Notch, and VEGF. | Q35176841 | ||
| PTEN controls tumor-induced angiogenesis | Q35282160 | ||
| Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity | Q35803081 | ||
| ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells | Q35853239 | ||
| Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development | Q35915549 | ||
| Inactivation of PTEN is associated with increased angiogenesis and VEGF overexpression in gastric cancer | Q36178164 | ||
| Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. | Q36301565 | ||
| Ptena and ptenb genes play distinct roles in zebrafish embryogenesis. | Q37032400 | ||
| The nuclear affairs of PTEN. | Q37063858 | ||
| Phosphorylation keeps PTEN phosphatase closed for business | Q37083611 | ||
| Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish. | Q37137760 | ||
| Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress | Q37380066 | ||
| A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development | Q37468040 | ||
| Pten function in zebrafish: anything but a fish story | Q38280829 | ||
| Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer | Q38893164 | ||
| PTEN inhibits the invasion and metastasis of gastric cancer via downregulation of FAK expression | Q39028266 | ||
| PTEN is destabilized by phosphorylation on Thr366. | Q40143795 | ||
| A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth | Q40184782 | ||
| Systemic elevation of PTEN induces a tumor-suppressive metabolic state | Q41968721 | ||
| Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN. | Q42117421 | ||
| Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3: implications for the control of protein stability and PTEN-protein interactions | Q44467149 | ||
| Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development. | Q47073952 | ||
| A zebrafish histone variant H2A.F/Z and a transgenic H2A.F/Z:GFP fusion protein for in vivo studies of embryonic development | Q48320990 | ||
| Repulsive guidance molecule A suppresses angiogenesis. | Q50896525 | ||
| Indigo naturalis and its component tryptanthrin exert anti-angiogenic effect by arresting cell cycle and inhibiting Akt and FAK signaling in human vascular endothelial cells. | Q52919371 | ||
| Cytoplasmic p27Kip1 counteracts the pro-apoptotic function of the open conformation of PTEN by retention and destabilization of PTEN outside of the nucleus. | Q53209647 | ||
| FAK mediates a compensatory survival signal parallel to PI3K-AKT in PTEN-null T-ALL cells. | Q54282770 | ||
| Phosphorylation of PTEN at STT motif is associated with DNA damage response. | Q55065400 | ||
| Nuclear PTEN: a tale of many tails | Q79448445 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e0154771 | |
| P577 | publication date | 2016-05-03 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Fine-Tuning of Pten Localization and Phosphatase Activity Is Essential for Zebrafish Angiogenesis | |
| P478 | volume | 11 |
| Q41062747 | A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. |
| Q64963270 | A clinical study on the expression of PTEN in renal cell carcinoma in children. |
| Q47164277 | Establishment of pten knockout medaka with transcription activator-like effector nucleases (TALENs) as a model of PTEN deficiency disease |
| Q47435142 | PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer. |
| Q39448315 | Recent advances in understanding the role of protein-tyrosine phosphatases in development and disease |
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