| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2016PLoSO..1148508S |
| P356 | DOI | 10.1371/JOURNAL.PONE.0148508 |
| P932 | PMC publication ID | 4743836 |
| P698 | PubMed publication ID | 26848951 |
| P5875 | ResearchGate publication ID | 293169268 |
| P2093 | author name string | Jeroen den Hertog | |
| Miriam Stumpf | |||
| P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
| Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function | Q24295164 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases | Q24323070 | ||
| Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway | Q24532136 | ||
| PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration | Q24677034 | ||
| Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association | Q27620298 | ||
| Crystal structure of human protein tyrosine phosphatase 1B | Q27731235 | ||
| Stages of embryonic development of the zebrafish | Q27860947 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions | Q28343581 | ||
| TPIP: a novel phosphoinositide 3-phosphatase | Q28364566 | ||
| Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
| Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
| PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activity | Q30434033 | ||
| Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway | Q30829981 | ||
| Allele-specific tumor spectrum in pten knockin mice | Q33740171 | ||
| Mutations of the human PTEN gene | Q33988995 | ||
| Functional analysis of the protein phosphatase activity of PTEN | Q34194118 | ||
| The catalytic mechanism of protein tyrosine phosphatases revisited | Q34286121 | ||
| Pivotal role of Pten in the balance between proliferation and differentiation of hematopoietic stem cells in zebrafish | Q52162285 | ||
| Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation. | Q55065488 | ||
| PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects | Q64379300 | ||
| The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling | Q77206124 | ||
| Mutational abrogation of the PTEN/MMAC1 gene in gastrointestinal polyps in patients with Cowden disease | Q77494213 | ||
| PTEN mutation in a family with Cowden syndrome and autism | Q34331855 | ||
| PTEN increases autophagy and inhibits the ubiquitin-proteasome pathway in glioma cells independently of its lipid phosphatase activity | Q35070903 | ||
| The identification and characterization of zebrafish hematopoietic stem cells | Q35112228 | ||
| The protein phosphatase activity of PTEN is essential for regulating neural stem cell differentiation | Q35595103 | ||
| Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma | Q35794584 | ||
| Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly | Q36053966 | ||
| Inactivation of PTEN is associated with increased angiogenesis and VEGF overexpression in gastric cancer | Q36178164 | ||
| The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway | Q36396479 | ||
| Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner | Q36760948 | ||
| Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
| Ptena and ptenb genes play distinct roles in zebrafish embryogenesis. | Q37032400 | ||
| Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish. | Q37137760 | ||
| The significance of PTEN's protein phosphatase activity | Q37376968 | ||
| A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development | Q37468040 | ||
| PTEN. | Q38218236 | ||
| Pten function in zebrafish: anything but a fish story | Q38280829 | ||
| Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase | Q38314871 | ||
| PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity | Q39388363 | ||
| Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN. | Q39774233 | ||
| Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. | Q40587498 | ||
| The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells | Q40993616 | ||
| PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation. | Q42527541 | ||
| Suppression of T-cell lymphomagenesis in mice requires PTEN phosphatase activity. | Q43065543 | ||
| Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer. | Q45029660 | ||
| Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells | Q47071826 | ||
| Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development. | Q47073952 | ||
| Germline mutations in PTEN are present in Bannayan-Zonana syndrome | Q48046915 | ||
| A zebrafish histone variant H2A.F/Z and a transgenic H2A.F/Z:GFP fusion protein for in vivo studies of embryonic development | Q48320990 | ||
| Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis. | Q48331127 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e0148508 | |
| P577 | publication date | 2016-02-05 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development | |
| P478 | volume | 11 |
| Q64963270 | A clinical study on the expression of PTEN in renal cell carcinoma in children. |
| Q101356242 | Comprehensive in silico mutational-sensitivity analysis of PTEN establishes signature regions implicated in pathogenesis of Autism Spectrum Disorders |
| Q36006472 | Fine-Tuning of Pten Localization and Phosphatase Activity Is Essential for Zebrafish Angiogenesis |
| Q47144111 | Impaired caudal fin-fold regeneration in zebrafish deficient for the tumor suppressor Pten. |
| Q90707597 | MicroRNA-26b/PTEN Signaling Pathway Mediates Glycine-Induced Neuroprotection in SAH Injury |
| Q39448315 | Recent advances in understanding the role of protein-tyrosine phosphatases in development and disease |
| Q49167741 | Shp2-Mitogen-Activated Protein Kinase Signaling Drives Proliferation during Zebrafish Embryo Caudal Fin Fold Regeneration |
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