scholarly article | Q13442814 |
P819 | ADS bibcode | 1997PNAS...94.1680F |
P356 | DOI | 10.1073/PNAS.94.5.1680 |
P8608 | Fatcat ID | release_ry6iba57fratvn7keglks6p3lm |
P3181 | OpenCitations bibliographic resource ID | 3204783 |
P932 | PMC publication ID | 19976 |
P698 | PubMed publication ID | 9050838 |
P5875 | ResearchGate publication ID | 14160297 |
P50 | author | Tony Tiganis | Q37382684 |
P2093 | author name string | N K Tonks | |
A J Flint | |||
D Barford | |||
P2860 | cites work | The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence | Q24301399 |
Substrate specificity of the protein tyrosine phosphatases | Q24309619 | ||
Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B | Q24311668 | ||
COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus | Q24316086 | ||
Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B | Q24557671 | ||
Cloning of a cDNA for a major human protein-tyrosine-phosphatase | Q24558722 | ||
A catalytic mechanism for the dual-specific phosphatases | Q24563405 | ||
Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST. | Q24647903 | ||
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 | ||
Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B | Q27729426 | ||
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate | Q27730850 | ||
Crystal structure of human protein tyrosine phosphatase 1B | Q27731235 | ||
Rapid and efficient site-specific mutagenesis without phenotypic selection | Q27860608 | ||
Cloning and expression of a protein-tyrosine-phosphatase | Q28577079 | ||
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo | Q29615244 | ||
Expression of a protein tyrosine phosphatase in normal and v-src-transformed mouse 3T3 fibroblasts | Q30442281 | ||
Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation | Q34050342 | ||
From form to function: signaling by protein tyrosine phosphatases. | Q34405391 | ||
Purification of the major protein-tyrosine-phosphatases of human placenta | Q34554142 | ||
Characterization of the major protein-tyrosine-phosphatases of human placenta. | Q34554150 | ||
Dissecting the catalytic mechanism of protein-tyrosine phosphatases | Q35063279 | ||
Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain | Q35886042 | ||
The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage | Q36232127 | ||
Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis | Q36799816 | ||
The Cys(X)5Arg catalytic motif in phosphoester hydrolysis | Q38301012 | ||
Protein tyrosine phosphatases take off. | Q41143264 | ||
Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast. | Q45949013 | ||
Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling | Q46765571 | ||
Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate | Q50335611 | ||
Protein tyrosine phosphatases and the control of cellular signaling responses | Q71475516 | ||
Purification and crystallization of the catalytic domain of human protein tyrosine phosphatase 1B expressed in Escherichia coli | Q72023400 | ||
Acidic residues are involved in substrate recognition by two soluble protein tyrosine phosphatases, PTP-5 and rrbPTP-1 | Q72609567 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1680-5 | |
P577 | publication date | 1997-03-04 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases | |
P478 | volume | 94 |
Q42595016 | A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. |
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Q40593923 | A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta). |
Q28592741 | A novel substrate of receptor tyrosine phosphatase PTPRO is required for nerve growth factor-induced process outgrowth |
Q52336555 | A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity. |
Q24676880 | AMSH is an endosome-associated ubiquitin isopeptidase |
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Q42451113 | Alterations in subcellular localization of p38 MAPK potentiates endothelin-stimulated COX-2 expression in glomerular mesangial cells. |
Q41075788 | Altered distribution and expression of protein tyrosine phosphatases in normal human skin as compared to squamous cell carcinomas |
Q41486377 | Altering the nucleophile specificity of a protein-tyrosine phosphatase-catalyzed reaction. Probing the function of the invariant glutamine residues |
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Q42977534 | Analysis of the redox regulation of protein tyrosine phosphatase superfamily members utilizing a cysteinyl-labeling assay |
Q74428342 | Anti-phosphatases take the stage |
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Q30363522 | Association of tyrosine phosphatase epsilon with microtubules inhibits phosphatase activity and is regulated by the epidermal growth factor receptor. |
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Q38289920 | Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B. |
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Q37596435 | Bracoviruses contain a large multigene family coding for protein tyrosine phosphatases. |
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Q28359634 | Comparative study of protein tyrosine phosphatase-epsilon isoforms: membrane localization confers specificity in cellular signalling |
Q47259128 | Computational modeling of the rate limiting step in low molecular weight protein tyrosine phosphatase |
Q40163127 | Consequences of direct versus indirect activation of epidermal growth factor receptor in intestinal epithelial cells are dictated by protein-tyrosine phosphatase 1B. |
Q30489519 | Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy |
Q92482618 | Control of protein function through oxidation and reduction of persulfidated states |
Q24301716 | Control of vesicle fusion by a tyrosine phosphatase |
Q30175917 | Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase |
Q34539371 | Coordinated action of protein tyrosine phosphatases in insulin signal transduction |
Q28594157 | Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP |
Q28137870 | Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase |
Q27657823 | Crystal Structures of the Histidine Acid Phosphatase from Francisella tularensis Provide Insight into Substrate Recognition |
Q27640358 | Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor |
Q27642841 | Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome |
Q27641444 | Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor |
Q22009892 | Crystal structure of the tandem phosphatase domains of RPTP LAR |
Q28143462 | Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation |
Q33285968 | Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries |
Q34213990 | Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia |
Q24310946 | Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells |
Q39738774 | Dephosphorylation of the adaptor LAT and phospholipase C-γ by SHP-1 inhibits natural killer cell cytotoxicity |
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Q40605597 | Development of an efficient "substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates |
Q24317296 | Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity |
Q35915549 | Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development |
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Q27937943 | Differential regulation of the cell wall integrity mitogen-activated protein kinase pathway in budding yeast by the protein tyrosine phosphatases Ptp2 and Ptp3. |
Q24313085 | Direct interaction between ER membrane-bound PTP1B and its plasma membrane-anchored targets |
Q34786070 | Disease-related Myotubularins Function in Endocytic Traffic inCaenorhabditis elegans |
Q34068353 | Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects β-cell function |
Q57980202 | Down-regulation of Insulin Signaling by Protein-tyrosine Phosphatase 1B Is Mediated by an N-terminal Binding Region |
Q44508750 | Downregulation of epidermal growth factor receptor signaling by singlet oxygen through activation of caspase-3 and protein phosphatases |
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Q24297779 | Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells |
Q27301222 | ER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interface |
Q37713633 | Ecdysone-induced receptor tyrosine phosphatase PTP52F regulates Drosophila midgut histolysis by enhancement of autophagy and apoptosis |
Q35842796 | Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts |
Q41994004 | Effects of Src Kinase Inhibition on Expression of Protein Tyrosine Phosphatase 1B after Brain Hypoxia in a Piglet Animal Model |
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Q37100021 | Histone H3 as a novel substrate for MAP kinase phosphatase-1. |
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Q24294879 | PTP1B regulates leptin signal transduction in vivo |
Q37728307 | PTP1B: a double agent in metabolism and oncogenesis |
Q34209253 | PTP1B: from the sidelines to the front lines! |
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Q34263558 | Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors |
Q51836870 | Photogenerated quinone methides as protein affinity labeling reagents. |
Q37611336 | Physiological signaling specificity by protein tyrosine phosphatases |
Q44283243 | Platelet-endothelial cell adhesion molecule-1 modulates endothelial migration through its immunoreceptor tyrosine-based inhibitory motif |
Q24298615 | Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1 |
Q30325800 | Prediction of a ligand-induced conformational change in the catalytic core of Cdc25A. |
Q33194214 | Probing protein-tyrosine phosphatase substrate specificity using a phosphotyrosine-containing phage library |
Q44112967 | Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition |
Q46935318 | Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane |
Q34805653 | Protein Tyrosine Phosphatase 1B (PTP1B) deficiency accelerates hepatic regeneration in mice |
Q38200472 | Protein phosphatases in pancreatic islets. |
Q43115433 | Protein phosphorylation and protein phosphatases. De Panne, Belgium, September 19-24, 1999. |
Q39228225 | Protein tyrosine phosphatase 1B (PTP1B) modulates palmitate-induced cytokine production in macrophage cells |
Q24311296 | Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo |
Q35002509 | Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling |
Q27305216 | Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes |
Q36437015 | Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies |
Q24296932 | Protein tyrosine phosphatase 1B participates in the down-regulation of erythropoietin receptor signalling |
Q36928998 | Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation |
Q37969987 | Protein tyrosine phosphatase 1B: a novel molecular target for retinal degenerative diseases |
Q24290951 | Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation |
Q41879189 | Protein tyrosine phosphatase PTP1B in cell adhesion and migration |
Q36729655 | Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of rat-1 fibroblasts and promotes differentiation of K562 cells |
Q35146110 | Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation |
Q44774251 | Protein tyrosine phosphatase epsilon activates Yes and Fyn in Neu-induced mammary tumor cells |
Q37387988 | Protein tyrosine phosphatase epsilon regulates integrin-mediated podosome stability in osteoclasts by activating Src. |
Q36713273 | Protein tyrosine phosphatase function: the substrate perspective |
Q40442779 | Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization |
Q36489196 | Protein tyrosine phosphatase-1B (PTP1B) helps regulate EGF-induced stimulation of S-phase entry in human corneal endothelial cells. |
Q24304888 | Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cells |
Q34023798 | Protein tyrosine phosphatase-1B in diabetes |
Q36798438 | Protein tyrosine phosphatase-1B regulates the tyrosine phosphorylation of the adapter Grb2-associated binder 1 (Gab1) in the retina |
Q34419522 | Protein tyrosine phosphatases in signal transduction. |
Q33565458 | Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation |
Q24622527 | Protein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transduction |
Q77946535 | Protein tyrosine phosphatases: counting the trees in the forest |
Q29614826 | Protein tyrosine phosphatases: from genes, to function, to disease |
Q53852755 | Protein tyrosine phosphatases: their role in insulin action and potential as drug targets. |
Q35185678 | Protein tyrosyl phosphatases in T cell activation: implication for human immunodeficiency virus transcriptional activity |
Q34509577 | Protein-tyrosine phosphatase 1B (PTP1B) is a novel regulator of central brain-derived neurotrophic factor and tropomyosin receptor kinase B (TrkB) signaling |
Q37112768 | Protein-tyrosine phosphatase 1B antagonized signaling by insulin-like growth factor-1 receptor and kinase BRK/PTK6 in ovarian cancer cells |
Q46761334 | Protein-tyrosine phosphatase 1B deficiency protects against Fas-induced hepatic failure |
Q24295233 | Protein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptors |
Q35118726 | Protein-tyrosine phosphatase 1B substrates and metabolic regulation |
Q39603499 | Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling |
Q46962386 | Protein-tyrosine phosphatase H1 controls growth hormone receptor signaling and systemic growth |
Q38362451 | Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells |
Q33832583 | Protein-tyrosine phosphatase PTPN9 negatively regulates ErbB2 and epidermal growth factor receptor signaling in breast cancer cells |
Q40033133 | Protein-tyrosine phosphatase epsilon regulates Shc signaling in a kinase-specific manner: increasing coherence in tyrosine phosphatase signaling |
Q48021656 | Protein-tyrosine phosphatase-1B acts as a negative regulator of insulin signal transduction |
Q36430193 | Protein-tyrosine phosphatases and cancer |
Q41739061 | Protein-tyrosine phosphatases: biological function, structural characteristics, and mechanism of catalysis |
Q35074889 | Proteomics: the first decade and beyond |
Q34381500 | Pulling strings below the surface: hormone receptor signaling through inhibition of protein tyrosine phosphatases |
Q51090377 | Quantitative Tyrosine Phosphoproteomics of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-treated Lung Adenocarcinoma Cells Reveals Potential Novel Biomarkers of Therapeutic Response. |
Q28468277 | Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells |
Q38252989 | R3 receptor tyrosine phosphatases: conserved regulators of receptor tyrosine kinase signaling and tubular organ development |
Q24300000 | Reactivation of oxidized PTP1B and PTEN by thioredoxin 1 |
Q33630136 | Reactive oxygen species play a critical role in collagen-induced platelet activation via SHP-2 oxidation |
Q24675717 | Receptor protein tyrosine phosphatase micro regulates the paracellular pathway in human lung microvascular endothelia |
Q24312704 | Receptor protein tyrosine phosphatase-receptor tyrosine kinase substrate screen identifies EphA2 as a target for LAR in cell migration |
Q33761927 | Receptor protein tyrosine phosphatases are novel components of a polycystin complex |
Q36731957 | Receptor tyrosine phosphatases regulate birth order-dependent axonal fasciculation and midline repulsion during development of the Drosophila mushroom body |
Q34963286 | Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function |
Q53045957 | Receptor-type protein tyrosine phosphatase κ directly dephosphorylates CD133 and regulates downstream AKT activation. |
Q24293413 | Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function |
Q27695708 | Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain-modulated complex formation |
Q27664961 | Recognition of Nucleoside Monophosphate Substrates by Haemophilus influenzae Class C Acid Phosphatase |
Q36476273 | Redox regulation of epidermal growth factor receptor signaling through cysteine oxidation |
Q37073431 | Redox regulation of interleukin-4 signaling |
Q35174581 | Redox regulation of protein kinases |
Q27641430 | Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate |
Q33800728 | Redox regulation of signal transduction in mammalian cells |
Q39802746 | Regulation and function of protein kinases and phosphatases |
Q36588906 | Regulation and functional relevance of milk fat globules and their components in the mammary gland |
Q41607150 | Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex. |
Q24653458 | Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway |
Q36741267 | Regulation of ROS signal transduction by NADPH oxidase 4 localization |
Q45923768 | Regulation of apoptotic potassium currents by coordinated zinc-dependent signalling. |
Q33815738 | Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1B |
Q28298939 | Regulation of cell adhesion by protein-tyrosine phosphatases. I. Cell-matrix adhesion |
Q53777253 | Regulation of dual-specificity phosphatases M3/6 and hVH5 by phorbol esters. Analysis of a delta-like domain. |
Q28511379 | Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes |
Q28295462 | Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST |
Q35108594 | Regulation of hERG and hEAG channels by Src and by SHP-1 tyrosine phosphatase via an ITIM region in the cyclic nucleotide binding domain |
Q24296501 | Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP |
Q44932599 | Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. |
Q24292424 | Regulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblasts |
Q42788780 | Regulation of interleukin-3-induced substrate phosphorylation and cell survival by SHP-2 (Src-homology protein tyrosine phosphatase 2). |
Q24299014 | Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase |
Q91756829 | Regulation of platelet-activating factor-mediated interleukin-6 promoter activation by the 48 kDa but not the 45 kDa isoform of protein tyrosine phosphatase non-receptor type 2 |
Q40672244 | Regulation of protein tyrosine phosphatase 1B in intact cells by S-nitrosothiols |
Q34288873 | Regulation of signaling at regions of cell-cell contact by endoplasmic reticulum-bound protein-tyrosine phosphatase 1B. |
Q24316395 | Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase |
Q42565548 | Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B |
Q42665532 | Relation between the flexibility of the WPD loop and the activity of the catalytic domain of protein tyrosine phosphatase SHP-1. |
Q41465181 | Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis. |
Q22253482 | Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatases 1B and alpha |
Q41650140 | Retinal axon target selection in Drosophila is regulated by a receptor protein tyrosine phosphatase |
Q29615579 | Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo |
Q33996724 | Role of JNK in network formation of human lung microvascular endothelial cells |
Q41514648 | Role of phosphatases in lymphocyte activation. |
Q33796479 | Role of protein phosphatases in the regulation of human mast cell and basophil function |
Q42199994 | Role of protein tyrosine phosphatase 1B in vascular endothelial growth factor signaling and cell-cell adhesions in endothelial cells |
Q43817828 | Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells |
Q33834442 | Roles of protein tyrosine phosphatases in cell migration and adhesion |
Q74129083 | SHP-1 associates with both platelet-derived growth factor receptor and the p85 subunit of phosphatidylinositol 3-kinase |
Q40550696 | SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway |
Q24292512 | SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription |
Q28284908 | SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors |
Q89722310 | SUMO Protease SMT7 Modulates Ribosomal Protein L30 and Regulates Cell-size Checkpoint Function |
Q33924999 | SUMOylation of Psmd1 controls Adrm1 interaction with the proteasome |
Q24294324 | Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase |
Q36301565 | Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. |
Q29617413 | Signaling--2000 and beyond |
Q36047190 | Simultaneous Enrichment of Cysteine-containing Peptides and Phosphopeptides Using a Cysteine-specific Phosphonate Adaptable Tag (CysPAT) in Combination with titanium dioxide (TiO2) Chromatography. |
Q36426218 | Slit and Receptor Tyrosine Phosphatase 69D Confer Spatial Specificity to Axon Branching via Dscam1. |
Q92607280 | Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4 |
Q34768047 | Specificity profiling of protein phosphatases toward phosphoseryl and phosphothreonyl peptides |
Q27936648 | Ssu72 Is an RNA polymerase II CTD phosphatase |
Q50891541 | Steered Molecular Dynamics for Investigating the Interactions Between Insulin Receptor Tyrosine Kinase (IRK) and Variants of Protein Tyrosine Phosphatase 1B (PTP1B). |
Q28546701 | Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1 |
Q52655508 | Structural and biochemical characterization of Siw14: a protein-tyrosine phosphatase fold that metabolizes inositol pyrophosphates. |
Q34012560 | Structural and evolutionary relationships among protein tyrosine phosphatase domains |
Q39631199 | Structural determinants of SHP-2 function and specificity in Xenopus mesoderm induction |
Q27631738 | Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme |
Q27638439 | Structure determination of T cell protein-tyrosine phosphatase |
Q35071031 | Structure-function analyses of tyrosine phosphatase PTP69D in giant fiber synapse formation of Drosophila |
Q39660456 | Studying the Regulation of MAP Kinase by MAP Kinase Phosphatases In Vitro and in Cell Systems |
Q27315888 | Subcellular Partitioning of Protein Tyrosine Phosphatase 1B to the Endoplasmic Reticulum and Mitochondria Depends Sensitively on the Composition of Its Tail Anchor |
Q37095466 | Substrate specificity of R3 receptor-like protein-tyrosine phosphatase subfamily toward receptor protein-tyrosine kinases |
Q24309015 | Substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate |
Q33811181 | Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2. |
Q34060655 | Sumo-dependent substrate targeting of the SUMO protease Ulp1 |
Q47608480 | Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase |
Q41485755 | Suramin is an active site-directed, reversible, and tight-binding inhibitor of protein-tyrosine phosphatases |
Q30541159 | Synaptic plasticity: one STEP at a time |
Q24297041 | T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice |
Q28590621 | T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation |
Q35806647 | T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts |
Q34005525 | TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells |
Q24291860 | TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B |
Q51577103 | Tailor-Made Protein Tyrosine Phosphatases: In Vitro Site-Directed Mutagenesis of PTEN and PTPRZ-B. |
Q33554884 | Targeting PTPs with small molecule inhibitors in cancer treatment |
Q45292159 | Teaching resources. Protein phosphatases |
Q41008340 | The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1. |
Q48207784 | The HECT E3 ubiquitin ligase NEDD4 interacts with and ubiquitylates SQSTM1 for inclusion body autophagy. |
Q39117221 | The LIM domain only 4 protein is a metabolic responsive inhibitor of protein tyrosine phosphatase 1B that controls hypothalamic leptin signaling. |
Q28145888 | The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTP |
Q35770577 | The Protein Tyrosine Phosphatase Rptpζ Suppresses Osteosarcoma Development in Trp53-Heterozygous Mice |
Q52937486 | The R3 receptor-like protein tyrosine phosphatase subfamily inhibits insulin signalling by dephosphorylating the insulin receptor at specific sites. |
Q58377593 | The Role of TCPTP in Cancer |
Q24306901 | The SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificities |
Q43074065 | The Salmonella effector SptP dephosphorylates host AAA+ ATPase VCP to promote development of its intracellular replicative niche |
Q24292506 | The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3 |
Q27661333 | The Trypanosoma brucei Life Cycle Switch TbPTP1 Is Structurally Conserved and Dephosphorylates the Nucleolar Protein NOPP44/46 |
Q43607722 | The YRD motif is a major determinant of substrate and inhibitor specificity in T-cell protein-tyrosine phosphatase |
Q40826483 | The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages |
Q27931733 | The activity of Cdc14p, an oligomeric dual specificity protein phosphatase from Saccharomyces cerevisiae, is required for cell cycle progression |
Q36403213 | The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation |
Q34308157 | The application of modular protein domains in proteomics |
Q43862884 | The catalytic mechanism of Cdc25A phosphatase |
Q37233379 | The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F. |
Q24620636 | The chemical biology of protein phosphorylation |
Q64101666 | The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion |
Q24682886 | The nonreceptor protein tyrosine phosphatase PTP1B binds to the cytoplasmic domain of N-cadherin and regulates the cadherin-actin linkage |
Q37405181 | The phosphatase SHP2 regulates the spacing effect for long-term memory induction |
Q37630230 | The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity |
Q28507911 | The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions |
Q24679774 | The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin |
Q40784926 | The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor. |
Q28144437 | The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling |
Q30009978 | The pseudophosphatase MK-STYX inhibits stress granule assembly independently of Ser149 phosphorylation of G3BP-1 |
Q30156949 | The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation |
Q31157967 | The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1 |
Q96765569 | The receptor PTPRU is a redox sensitive pseudophosphatase |
Q37428899 | The receptor protein tyrosine phosphatase LAR promotes R7 photoreceptor axon targeting by a phosphatase-independent signaling mechanism. |
Q24299978 | The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1 |
Q24622106 | The role of protein tyrosine phosphatase 1B in Ras signaling |
Q24301273 | The role of protein-tyrosine phosphatase 1B in integrin signaling |
Q77631111 | The second domain of the CD45 protein tyrosine phosphatase is critical for interleukin-2 secretion and substrate recruitment of TCR-zeta in vivo |
Q30498983 | The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala |
Q27633455 | The structure of apo protein-tyrosine phosphatase 1B C215S mutant: More than just an S → O change |
Q28141335 | The transmembrane protein tyrosine phosphatase RPTPsigma modulates signaling of the epidermal growth factor receptor in A431 cells |
Q24310022 | The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn) |
Q24307844 | The tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linking |
Q34654408 | The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling |
Q52540578 | Thermodynamic study of ligand binding to protein-tyrosine phosphatase 1B and its substrate-trapping mutants. |
Q40023975 | Transmembrane glycoprotein gp150 is a substrate for receptor tyrosine phosphatase DPTP10D in Drosophila cells |
Q34365568 | Trypanosomatid protein phosphatases |
Q27315422 | Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling |
Q36308947 | Tyrosine phosphatase PTP-MEG2 negatively regulates vascular endothelial growth factor receptor signaling and function in endothelial cells |
Q40623571 | Tyrosine phosphatase PTP1B modulates store-operated calcium influx. |
Q28247569 | Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4 |
Q44323339 | Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells |
Q35128273 | Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells |
Q38953607 | Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation |
Q24676902 | Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro |
Q40816324 | Tyrosine-phosphorylated caveolin is a physiological substrate of the low M(r) protein-tyrosine phosphatase |
Q30663794 | Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode |
Q51577059 | Use of Dominant-Negative/Substrate Trapping PTP Mutations to Search for PTP Interactors/Substrates. |
Q30539522 | VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation |
Q35661770 | Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity |
Q30159671 | Vinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface |
Q27749490 | Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by x-ray crystallography |
Q28086901 | Voltage sensitive phosphatases: emerging kinship to protein tyrosine phosphatases from structure-function research |
Q34026657 | Why is PTPN22 a good candidate susceptibility gene for autoimmune disease? |
Q88754820 | miCLIP-MaPseq, a Substrate Identification Approach for Radical SAM RNA Methylating Enzymes |
Q35604861 | γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. |