| scholarly article | Q13442814 |
| P50 | author | Manuela Klingler-Hoffmann | Q37382658 |
| Tony Tiganis | Q37382684 | ||
| Sandra Galic | Q54345991 | ||
| P2093 | author name string | Michelle A Puryer | |
| Nicholas K Tonks | |||
| Tzu-Ching Meng | |||
| Michelle T Fodero-Tavoletti | |||
| P2860 | cites work | Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells | Q24290688 |
| Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B | Q24290779 | ||
| TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B | Q24291860 | ||
| Insulin signalling and the regulation of glucose and lipid metabolism | Q24292020 | ||
| The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3 | Q24292506 | ||
| PTP1B regulates leptin signal transduction in vivo | Q24294879 | ||
| Identification of a nuclear Stat1 protein tyrosine phosphatase | Q24302061 | ||
| Structural diversity and evolution of human receptor-like protein tyrosine phosphatases | Q24307709 | ||
| Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains | Q24310517 | ||
| COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus | Q24316086 | ||
| Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases | Q24323070 | ||
| Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase | Q24522441 | ||
| Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice | Q24552910 | ||
| Cloning and expression of a widely expressed receptor tyrosine phosphatase | Q24557510 | ||
| Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B | Q24557671 | ||
| Cloning of a cDNA for a major human protein-tyrosine-phosphatase | Q24558722 | ||
| Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST. | Q24647903 | ||
| Structure determination of T cell protein-tyrosine phosphatase | Q27638439 | ||
| Crystal structure of human protein tyrosine phosphatase 1B | Q27731235 | ||
| The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling | Q28144437 | ||
| A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus | Q28214398 | ||
| Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase | Q28217313 | ||
| Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97 | Q28246489 | ||
| The IRS-signalling system: a network of docking proteins that mediate insulin action | Q28272481 | ||
| Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST | Q28295462 | ||
| Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance | Q28363155 | ||
| Identification of an additional member of the protein-tyrosine-phosphatase family: evidence for alternative splicing in the tyrosine phosphatase domain | Q28505143 | ||
| Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice | Q28594549 | ||
| Insulin signalling | Q28611467 | ||
| Insulin receptor-associated protein tyrosine phosphatase(s): role in insulin action | Q28616328 | ||
| Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta) | Q29615537 | ||
| Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene | Q29618933 | ||
| A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes | Q33960388 | ||
| Structural and evolutionary relationships among protein tyrosine phosphatase domains | Q34012560 | ||
| The T-cell protein tyrosine phosphatase | Q34038105 | ||
| Protein tyrosine phosphatases: dephosphorylating the epidermal growth factor receptor | Q34129090 | ||
| Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatase-1B. | Q34158339 | ||
| Combinatorial control of the specificity of protein tyrosine phosphatases | Q34180660 | ||
| Purification of the major protein-tyrosine-phosphatases of human placenta | Q34554142 | ||
| Characterization of the major protein-tyrosine-phosphatases of human placenta. | Q34554150 | ||
| Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B. | Q38289920 | ||
| Differential activities of protein tyrosine phosphatases in intact cells | Q38315120 | ||
| The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor. | Q40784926 | ||
| Murine embryonic fibroblasts lacking TC-PTP display delayed G1 phase through defective NF-kappaB activation | Q40786997 | ||
| PTP-S2, a nuclear tyrosine phosphatase, is phosphorylated and excluded from condensed chromosomes during mitosis | Q40877903 | ||
| Receptor-like protein-tyrosine phosphatase alpha specifically inhibits insulin-increased prolactin gene expression | Q41059034 | ||
| Protein tyrosine phosphatases take off. | Q41143264 | ||
| The insulin signalling system and the IRS proteins | Q41555426 | ||
| Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation | Q42486150 | ||
| Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo | Q42816311 | ||
| Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin | Q42825844 | ||
| Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase TCPTP. | Q42826816 | ||
| Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum | Q43901714 | ||
| Regulation of the insulin signalling pathway by cellular protein-tyrosine phosphatases | Q48021665 | ||
| Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis. | Q51571073 | ||
| Impaired mammary gland development and function in mice lacking LAR receptor-like tyrosine phosphatase activity. | Q52193356 | ||
| The Noncatalytic C-terminal Segment of the T Cell Protein Tyrosine Phosphatase Regulates Activity via an Intramolecular Mechanism | Q58377628 | ||
| Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle | Q72952422 | ||
| Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants | Q73586208 | ||
| The juxtamembrane but not the carboxyl-terminal domain of the insulin receptor mediates insulin's metabolic functions in primary adipocytes and cultured hepatoma cells | Q73828830 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| preproinsulin | Q7240673 | ||
| protein tyrosine phosphatase activity | Q14878341 | ||
| Protein tyrosine phosphatase non-receptor type 2 | Q21171735 | ||
| Protein tyrosine phosphatase, non-receptor type 2 | Q21990494 | ||
| P304 | page(s) | 2096-108 | |
| P577 | publication date | 2003-03-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP | |
| P478 | volume | 23 |
| Q35010920 | A new highly efficient substrate-trapping mutant of protein tyrosine phosphatase 1B (PTP1B) reveals full autoactivation of the insulin receptor precursor |
| Q33260614 | A two stage click-based library of protein tyrosine phosphatase inhibitors |
| Q33500778 | Acquisition of a potent and selective TC-PTP inhibitor via a stepwise fluorophore-tagged combinatorial synthesis and screening strategy |
| Q92989379 | Activation of Insulin Signaling in Adipocytes and Myotubes by Sarcopoterium Spinosum Extract |
| Q34989162 | Activation of protein tyrosine phosphatase non-receptor type 2 by spermidine exerts anti-inflammatory effects in human THP-1 monocytes and in a mouse model of acute colitis |
| Q35611046 | Adipose-specific deletion of Src homology phosphatase 2 does not significantly alter systemic glucose homeostasis |
| Q90745613 | Advances in Knowledge of Candidate Genes Acting at the Beta-Cell Level in the Pathogenesis of T1DM |
| Q34682216 | An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells |
| Q36512624 | Central regulation of metabolism by protein tyrosine phosphatases |
| Q28594157 | Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP |
| Q37274802 | Differential regulation of FGFR3 by PTPN1 and PTPN2. |
| Q24336003 | Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase |
| Q30152628 | Differential regulation of protein tyrosine kinase signaling by Dock and the PTP61F variants |
| Q33706954 | Enhancement of insulin responsiveness by nitric oxide-mediated inactivation of protein-tyrosine phosphatases |
| Q46746225 | Estrogen and insulin-like growth factor 1 synergistically promote the development of lung adenocarcinoma in mice |
| Q39377665 | Estrogen upregulates the IGF-1 signaling pathway in lung cancer through estrogen receptor-β. |
| Q33678110 | Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium |
| Q46489494 | Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice |
| Q40386669 | Identification of MMP-15 as an anti-apoptotic factor in cancer cells |
| Q34107651 | Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice |
| Q30976460 | Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase |
| Q39163034 | Inhibitors of Protein Tyrosine Phosphatase 1B from Marine Natural Products |
| Q37666434 | Inputs and outputs of insulin receptor |
| Q48056892 | Insulin action in the brain: Roles in energy and glucose homeostasis |
| Q33865202 | Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination |
| Q39085121 | Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) beta-receptor but not the PDGF alpha-receptor |
| Q34212116 | Loss of protein tyrosine phosphatase N2 potentiates epidermal growth factor suppression of intestinal epithelial chloride secretion |
| Q41550474 | Loss of protein tyrosine phosphatase, non-receptor type 2 is associated with activation of AKT and tamoxifen resistance in breast cancer |
| Q33858514 | Metabolic regulation by protein tyrosine phosphatases |
| Q41218016 | Microbial sensing by the intestinal epithelium in the pathogenesis of inflammatory bowel disease |
| Q24321559 | Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP |
| Q92748155 | Neonatal nutritional programming induces gliosis and alters the expression of T-cell protein tyrosine phosphatase and connexins in male rats |
| Q37992232 | PTP1B and TCPTP--nonredundant phosphatases in insulin signaling and glucose homeostasis |
| Q91671317 | PTPN2 Downregulation Is Associated with Albuminuria and Vitamin D Receptor Deficiency in Type 2 Diabetes Mellitus |
| Q90263941 | PTPN2 deficiency along with activation of nuclear Akt predict endocrine resistance in breast cancer |
| Q34211942 | PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background |
| Q37193767 | PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis |
| Q34644615 | Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice |
| Q33592510 | Pancreatic T cell protein-tyrosine phosphatase deficiency ameliorates cerulein-induced acute pancreatitis |
| Q24318292 | Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells |
| Q39429947 | Potent and selective inhibition of T-cell protein tyrosine phosphatase (TCPTP) by a dinuclear copper(II) complex. |
| Q33793839 | Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2 |
| Q58749617 | Protein Tyrosine Phosphatases as Potential Regulators of STAT3 Signaling |
| Q36713273 | Protein tyrosine phosphatase function: the substrate perspective |
| Q37088189 | Protein tyrosine phosphatases and type 1 diabetes: genetic and functional implications of PTPN2 and PTPN22 |
| Q24295233 | Protein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptors |
| Q39336319 | Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2. |
| Q44932599 | Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. |
| Q91756829 | Regulation of platelet-activating factor-mediated interleukin-6 promoter activation by the 48 kDa but not the 45 kDa isoform of protein tyrosine phosphatase non-receptor type 2 |
| Q24316395 | Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase |
| Q36184179 | Role of insulin-induced reactive oxygen species in the insulin signaling pathway |
| Q38165106 | Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance |
| Q24294324 | Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase |
| Q24308779 | Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase |
| Q26852276 | Small molecule tools for functional interrogation of protein tyrosine phosphatases |
| Q37289295 | Spermidine stimulates T cell protein-tyrosine phosphatase-mediated protection of intestinal epithelial barrier function. |
| Q34270913 | Strain-dependent differences in bone development, myeloid hyperplasia, morbidity and mortality in ptpn2-deficient mice. |
| Q37326060 | T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice |
| Q28592080 | T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis |
| Q24338883 | T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6 |
| Q34005525 | TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells |
| Q33980542 | TC-PTP directly interacts with connexin43 to regulate gap junction intercellular communication |
| Q37713024 | Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development |
| Q24607854 | The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction |
| Q52937486 | The R3 receptor-like protein tyrosine phosphatase subfamily inhibits insulin signalling by dephosphorylating the insulin receptor at specific sites. |
| Q91994816 | The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance |
| Q58377593 | The Role of TCPTP in Cancer |
| Q40576961 | The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis |
| Q46907819 | The catalytic activity of the eukaryotic initiation factor-2alpha kinase PKR is required to negatively regulate Stat1 and Stat3 via activation of the T-cell protein-tyrosine phosphatase |
| Q39439209 | The kinase c-Src and the phosphatase TC45 coordinately regulate c-Fos tyrosine phosphorylation and c-Fos phospholipid synthesis activation capacity |
| Q36759890 | The nucleus- and endoplasmic reticulum-targeted forms of protein tyrosine phosphatase 61F regulate Drosophila growth, life span, and fecundity |
| Q24299431 | Tyrosine phosphorylation of a SNARE protein, syntaxin 17: implications for membrane trafficking in the early secretory pathway |
Search more.