The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation

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The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ20091383
P932PMC publication ID2873733
P698PubMed publication ID20180778
P5875ResearchGate publication ID41561080

P2093author name stringMichael P Myers
Nicholas K Tonks
Lizabeth A Allison
Shantá D Hinton
Vincent R Roggero
P2860cites workMathematical models of protein kinase signal transduction.Q52039321
Principles behind the multifarious control of signal transductionQ57393856
Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domainsQ22003889
Crystal structure of the tandem phosphatase domains of RPTP LARQ22009892
The IA-2 interactomeQ24293778
The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth diseaseQ24306773
Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transitionQ24313264
A Ras-GTPase-activating protein SH3-domain-binding proteinQ24316153
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatasesQ24323070
A novel phosphorylation-dependent RNase activity of GAP-SH3 binding protein: a potential link between signal transduction and RNA stabilityQ24522539
The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm productionQ24529833
Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucomaQ24532011
RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localizationQ24548269
The RasGAP-associated endoribonuclease G3BP assembles stress granulesQ24671936
Stress granules and processing bodies are dynamically linked sites of mRNP remodelingQ24678779
Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumorsQ28206195
Rasputin, more promiscuous than ever: a review of G3BPQ28298633
Protein tyrosine phosphatases: from genes, to function, to diseaseQ29614826
RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granulesQ29615265
Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP).Q30158060
Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in ras- and Rho-mediated signalingQ30175218
Substrate-trapping techniques in the identification of cellular PTP targetsQ34374862
EWS-FLI1 target genes recovered from Ewing's sarcoma chromatinQ34398493
LKB1-dependent signaling pathwaysQ34535140
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathwaysQ34845865
mRNA degradation machines in eukaryotic cellsQ35011995
The structure and regulation of myotubularin phosphatasesQ36313678
Myotubularin phosphatases: policing 3-phosphoinositidesQ36530570
Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatasesQ36603867
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases.Q36819391
The JAK kinases: not just another kinase drug discovery targetQ37250023
Expression and function of IA-2 family proteins, unique neuroendocrine-specific protein-tyrosine phosphatasesQ37528867
A single mutation converts a novel phosphotyrosine binding domain into a dual-specificity phosphatase.Q38289397
Crystal structure of the major diabetes autoantigen insulinoma-associated protein 2 reveals distinctive immune epitopesQ40256865
A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta).Q40593923
G3BP is overexpressed in human tumors and promotes S phase entryQ42832825
Pseudophosphatases: grab and hold on.Q43251271
Modulation of specific protein expression levels by PTEN: identification of AKAP121, DHFR, G3BP, Rap1, and RCC1 as potential targets of PTEN.Q46396119
IA-2 (islet cell antigen 512) is the primary target of humoral autoimmunity against type 1 diabetes-associated tyrosine phosphatase autoantigens.Q50158841
P275copyright licenseCreative Commons Attribution-NonCommercial 2.5 GenericQ19113746
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectregulation of stress granule assemblyQ54810457
positive regulation of stress granule assemblyQ54810458
negative regulation of stress granule assemblyQ54810459
G3BP stress granule assembly factor 1Q21112719
Serine/threonine/tyrosine interacting like 1Q21135934
P304page(s)349-357
P577publication date2010-04-14
P1433published inBiochemical JournalQ864221
P1476titleThe pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation
P478volume427

Reverse relations

cites work (P2860)
Q51577082Analyzing Pseudophosphatase Function.
Q39241478Antagonistic roles for STYX pseudophosphatases in neurite outgrowth
Q27974726Atypical mitogen-activated protein kinase phosphatase implicated in regulating transition from pre-S-Phase asexual intraerythrocytic development of Plasmodium falciparum
Q27309029G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits
Q21199585Genome-wide matching of genes to cellular roles using guilt-by-association models derived from single sample analysis
Q27974727In silico characterization of an atypical MAPK phosphatase of Plasmodium falciparum as a suitable target for drug discovery
Q24308033Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants
Q36506947Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation
Q47132858MK-STYX Alters the Morphology of Primary Neurons, and Outgrowths in MK-STYX Overexpressing PC-12 Cells Develop a Neuronal Phenotype
Q36427519Phosphotyrosine recognition domains: the typical, the atypical and the versatile
Q43638244Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms.
Q24622527Protein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transduction
Q64062337Pseudophosphatase MK-STYX Alters Histone Deacetylase 6 Cytoplasmic Localization, Decreases Its Phosphorylation, and Increases Detyrosination of Tubulin
Q38142438Pseudophosphatases: methods of analysis and physiological functions
Q37992291Regulation of stress granules in virus systems
Q38634867The extended human PTPome: a growing tyrosine phosphatase family
Q35494912The pseudophosphatase MK-STYX induces neurite-like outgrowths in PC12 cells.
Q30009978The pseudophosphatase MK-STYX inhibits stress granule assembly independently of Ser149 phosphorylation of G3BP-1
Q31157967The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1

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