Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity

scientific article published on 10 March 2009

Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/0008-5472.CAN-08-1547
P932PMC publication ID2759716
P698PubMed publication ID19276385

P50authorErwin G. Van MeirQ30503507
P2093author name stringGang Chen
Daniel J Brat
Jeffrey J Olson
Nigel Mackman
Vladimir E Belozerov
Donald L Durden
Carol Tucker-Burden
Yuan Rong
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Regulation of the tissue factor geneQ28293617
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Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectorsQ29547596
The phosphatidylinositol 3-Kinase AKT pathway in human cancerQ29547860
AP-1 as a regulator of cell life and deathQ29616558
High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalancesQ33259264
Signaling by the germinal center kinase family of protein kinasesQ33534707
Extrinsic-pathway activation in cancer with high factor VIIa and tissue factorQ34057583
Molecular basis for the relationship between thrombosis and cancerQ34342948
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplificationQ34350623
Targeting the PI3K-Akt pathway in human cancer: rationale and promiseQ35571372
A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicityQ35660849
Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastomaQ35678312
Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and-independent mechanismsQ35850648
Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestationQ36417683
'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesisQ36510818
NF-kappaB and cancer-identifying targets and mechanismsQ36984251
Intravascular thrombosis in central nervous system malignancies: a potential role in astrocytoma progression to glioblastomaQ37029795
Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor kappa B, and Egr-1.Q38289775
Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanismsQ38311379
EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanismsQ38314949
A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growthQ40184782
Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomasQ40383820
PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma.Q40453813
Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesisQ40502054
Human Bcl-2 activates ERK signaling pathway to regulate activating protein-1, lens epithelium-derived growth factor and downstream genes.Q40522883
Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell populationQ40590816
Elevated JNK activation contributes to the pathogenesis of human brain tumorsQ42524158
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.Q42807109
Regulation of angiogenesis by tissue factor cytoplasmic domain signalingQ44034416
PTEN mutations in gliomas and glioneuronal tumors.Q47995275
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brainQ48583425
Expression of tissue factor correlates with grade of malignancy in human glioma.Q55479707
Patient age, histologic features, and length of survival in patients with glioblastoma multiforme.Q55487073
In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast diseaseQ70934414
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectglioblastomaQ282142
P304page(s)2540-2549
P577publication date2009-03-10
P1433published inCancer ResearchQ326097
P1476titleEpidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity
P478volume69

Reverse relations

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