Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity

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Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/JMCB/MJV020
P8608Fatcat IDrelease_adotswim2napfkclcmawgdmwzy
P698PubMed publication ID25801959
P5875ResearchGate publication ID276089483

P50authorJenny M. GunnersenQ43201239
Jason A. HowittQ44203516
John SilkeQ50630660
P2093author name stringAnh Doan
Jenny Lackovic
Seong-Seng Tan
Ulrich Putz
Ley-Hian Low
Choo-Peng Goh
P2860cites workThe regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionQ21245733
Ubiquitination regulates PTEN nuclear import and tumor suppressionQ24292946
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromesQ24320313
Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941Q24321567
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent mannerQ24337323
Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2Q24623513
Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteinsQ24645749
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathwayQ24653458
Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neuronsQ24657218
Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutationsQ24673663
The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancerQ27651832
Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of DrosophilaQ28249018
Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disordersQ28279421
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORsQ28286431
A secreted PTEN phosphatase that enters cells to alter signaling and survivalQ28292188
Nuclear PTEN levels and G2 progression in melanoma cellsQ28391204
Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammationQ28510102
Pten regulates neuronal arborization and social interaction in miceQ28512488
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
PTEN: a crucial mediator of mitochondria-dependent apoptosisQ28568382
PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activityQ30434033
Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsyQ30525675
Genome-scale RNAi profiling of cell division in human tissue culture cellsQ30836392
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer modelQ32069431
PTEN mutations as a cause of constitutive insulin sensitivity and obesity.Q33811688
Tumor suppressor PTEN acts through dynamic interaction with the plasma membraneQ34574432
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.Q34575151
Cellular up-regulation of Nedd4 family interacting protein 1 (Ndfip1) using low levels of bioactive cobalt complexesQ34624481
Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemiaQ35666277
PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancersQ35747653
Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumorsQ35810225
PTEN, more than the AKT pathwayQ36753139
Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cellsQ37587748
Specific inhibition of PTEN expression reverses hyperglycemia in diabetic miceQ38290824
Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression.Q40198370
Identification of PTEN at the ER and MAMs and its regulation of Ca(2+) signaling and apoptosis in a protein phosphatase-dependent mannerQ41835165
Differences in cyclin D2 and D1 protein expression distinguish forebrain progenitor subsetsQ42683659
The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cellsQ48362692
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivoQ48722189
Rab5 and Ndfip1 are involved in Pten ubiquitination and nuclear traffickingQ48792418
Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanomaQ57591227
P433issue2
P304page(s)119-131
P577publication date2015-03-23
P1433published inJournal of Molecular Cell BiologyQ2456339
P1476titleNdfip1 represses cell proliferation by controlling Pten localization and signaling specificity
P478volume7

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cites work (P2860)
Q52597824Cross-talk between monocyte invasion and astrocyte proliferation regulates scarring in brain injury.
Q42508857Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate
Q49746337MiR-155 Promotes Uveal Melanoma Cell Proliferation and Invasion by Regulating NDFIP1 Expression
Q90707597MicroRNA-26b/PTEN Signaling Pathway Mediates Glycine-Induced Neuroprotection in SAH Injury
Q90216457MicroRNA‑4712‑5p promotes proliferation of the vulvar squamous cell carcinoma cell line A431 by targeting PTEN through the AKT/cyclin D1 signaling pathways
Q47435142PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer.
Q38800014Shikonin Derivative DMAKO-05 Inhibits Akt Signal Activation and Melanoma Proliferation.
Q92889066The miR-873/NDFIP1 axis promotes hepatocellular carcinoma growth and metastasis through the AKT/mTOR-mediated Warburg effect

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