Redox Regulation of the Tumor Suppressor PTEN by Hydrogen Peroxide and Tert-Butyl Hydroperoxide

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Redox Regulation of the Tumor Suppressor PTEN by Hydrogen Peroxide and Tert-Butyl Hydroperoxide is …
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scholarly articleQ13442814

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P356DOI10.3390/IJMS18050982
P932PMC publication ID5454895
P698PubMed publication ID28489026

P2093author name stringYing Zhang
Tae-Hoon Lee
Inyoung Kim
Iha Park
Seung-Rock Lee
Seok Mo Kim
Kee-Oh Chay
Seong-Jeong Han
Dong Il Jang
P2860cites workGeneration of free radicals from organic hydroperoxide tumor promoters in isolated mouse keratinocytes. Formation of alkyl and alkoxyl radicals from tert-butyl hydroperoxide and cumene hydroperoxideQ42488222
Mitogen-activated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: implications for cellular survival and tumor promotion.Q42554705
Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family membersQ45267497
Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins.Q45345908
DNA methylation at the C-5 position of cytosine by methyl radicals: a possible role for epigenetic change during carcinogenesis by environmental agents.Q45971364
Regulation of the catalytic activity and structure of human thioredoxin 1 via oxidation and S-nitrosylation of cysteine residuesQ46547435
Reactive oxygen-mediated protein oxidation in aging and diseaseQ48027881
PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins.Q51317623
PTEN gene: a model for genetic diseases in dermatology.Q51597378
Genetic changes in the PTEN gene and their association with breast cancer in Pakistan.Q53666940
tert-butyl hydroperoxide kills cultured hepatocytes by peroxidizing membrane lipidsQ69951506
t-butyl hydroperoxide-induced perturbations of human erythrocytes as a model for oxidant stressQ70105180
In vivo metabolism of tert-butyl hydroperoxide to methyl radicals. EPR spin-trapping and DNA methylation studiesQ73194269
Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondriaQ73218399
Immunohistochemical expression of PTEN and beta-catenin for endometrial intraepithelial neoplasia in Japanese womenQ79914415
Reactivation of oxidized PTP1B and PTEN by thioredoxin 1Q24300000
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
A membrane-associated thioredoxin required for plant growth moves from cell to cell, suggestive of a role in intercellular communicationQ24624138
Focus on PTEN RegulationQ26797287
Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimerQ27733385
Synthesis and function of 3-phosphorylated inositol lipidsQ28200755
Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenograftsQ28289062
Hydroperoxide metabolism in mammalian organsQ29614205
Reversible inactivation of the tumor suppressor PTEN by H2O2Q29615204
Phosphoinositide kinasesQ29618047
Reactive oxygen species, antioxidants, and the mammalian thioredoxin systemQ29619367
The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathwayQ33564954
Redox regulation of cell survival by the thioredoxin superfamily: an implication of redox gene therapy in the heartQ33649846
Combined PTEN Mutation and Protein Expression Associate with Overall and Disease-Free Survival of Glioblastoma Patients.Q33912410
12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatasesQ34115614
PTEN: The down side of PI 3-kinase signalling.Q34540849
PTEN acetylation modulates its interaction with PDZ domainQ34817146
Role of Akt/protein kinase B in metabolism.Q34997136
Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activityQ35076291
Routes of formation and toxic consequences of lipid oxidation products in foodsQ35891150
Redox regulation of PI 3-kinase signalling via inactivation of PTENQ36266420
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progressionQ36638098
A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cellsQ36786894
An overview of the relationship between oxidative stress and chemical carcinogenesisQ37223291
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factorsQ37693081
PTEN.Q38218236
Role of 6-shogaol in tert -butyl hydroperoxide-induced apoptosis of HepG2 cellsQ39012338
Prooxidant states and tumor promotionQ39492603
Redox regulation of the tumor suppressor PTEN by glutathioneQ39679407
Role of reactive intermediates in tumor promotion and progression.Q40929596
Alternative Mechanisms for Hydroperoxide-Induced DNA Single Strand BreakageQ41107251
Biochemistry and pathology of radical-mediated protein oxidationQ41481967
Assay of the redox state of the tumor suppressor PTEN by mobility shiftQ41503771
Mechanism of the antimycin A-mediated enhancement of t-butylhydroperoxide-induced single-strand breakage in DNA.Q41874870
Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes.Q42088521
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P577publication date2017-05-10
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleRedox Regulation of the Tumor Suppressor PTEN by Hydrogen Peroxide and Tert-Butyl Hydroperoxide
P478volume18

Reverse relations

Q92906114Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functionscites workP2860

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