MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

scientific article published on March 2008

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1034356455
P356DOI10.1038/CR.2008.24
P8608Fatcat IDrelease_3ipr7yejk5bqndtge5wf7h2l54
P698PubMed publication ID18270520
P5875ResearchGate publication ID5580638

P2093author name stringShijie Sheng
Hailong Wu
Yin-Yuan Mo
Daotai Nie
Fangting Wu
Shuomin Zhu
P2860cites workPrinciples of microRNA-target recognitionQ21146368
Akt phosphorylates and regulates Pdcd4 tumor suppressor proteinQ24298858
Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-betaQ24302305
Real-time quantification of microRNAs by stem-loop RT-PCRQ24535510
miR-15 and miR-16 induce apoptosis by targeting BCL2Q24536069
Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasionQ24538826
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaQ24539231
A microRNA expression signature of human solid tumors defines cancer gene targetsQ24541455
Accumulation of miR-155 and BIC RNA in human B cell lymphomasQ24556523
RAS is regulated by the let-7 microRNA familyQ27860522
Unique microRNA molecular profiles in lung cancer diagnosis and prognosisQ27860631
MicroRNAs modulate hematopoietic lineage differentiationQ27860661
MicroRNA gene expression deregulation in human breast cancerQ27860690
Oncomirs - microRNAs with a role in cancerQ27860773
c-Myc-regulated microRNAs modulate E2F1 expressionQ27861046
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Vertebrate tropomyosin: distribution, properties and functionQ28216589
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cellsQ28262214
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survivalQ28264400
S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growthQ28269583
The biology and clinical relevance of the PTEN tumor suppressor pathwayQ28272157
Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1)Q28277655
Tumor suppressive maspin and epithelial homeostasisQ28285186
The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translationQ28504536
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell linesQ28975767
Ribo-gnome: the big world of small RNAsQ29615681
miR-21-mediated tumor growthQ29616149
miRNAs, cancer, and stem cell divisionQ29618925
Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferaseQ33220470
A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomasQ33270040
Regulation of microfilament organization and anchorage-independent growth by tropomyosin 1.Q33706258
MicroRNAs in cell proliferation, cell death, and tumorigenesis.Q34497050
Expression profiling identifies microRNA signature in pancreatic cancerQ34588109
MicroRNA biogenesis and cancerQ36113847
MicroRNA function: multiple mechanisms for a tiny RNA?Q36325449
MicroRNAs as oncogenesQ36345302
MicroRNA expression profiles in head and neck cancer cell linesQ38302158
MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).Q38303663
Association of human DNA topoisomerase IIalpha with mitotic chromosomes in mammalian cells is independent of its catalytic activityQ38320085
Maspin augments proteasome inhibitor-induced apoptosis in prostate cancer cellsQ40141260
Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factorsQ40171554
Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor systemQ40291677
PTEN up-regulates the tumor metastasis suppressor gene Drg-1 in prostate and breast cancer.Q40497377
Expression and regulation of genes associated with cell death during murine preimplantation embryo developmentQ48931238
Multiplexing RT-PCR for the detection of multiple miRNA species in small samples.Q54614283
MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical BehaviorQ57200299
Plasma Urokinase Receptor Levels in Patients With Colorectal Cancer: Relationship to PrognosisQ63753630
P433issue3
P921main subjectmicroRNAQ310899
P304page(s)350-359
P577publication date2008-03-01
P1433published inCell ResearchQ1524018
P1476titleMicroRNA-21 targets tumor suppressor genes in invasion and metastasis
P478volume18

Reverse relations

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Q36523888MicroRNA-205 increases the sensitivity of docetaxel in breast cancer
Q39283860MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN.
Q39455098MicroRNA-21 Down-regulates Rb1 Expression by Targeting PDCD4 in Retinoblastoma
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Q35070803MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.
Q33426268MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression
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Q45330530MicroRNA-21 mediates the rapamycin-induced suppression of endothelial proliferation and migration
Q28117223MicroRNA-21 modulates the levels of reactive oxygen species by targeting SOD3 and TNFα
Q34426103MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration
Q34139065MicroRNA-21 promotes glioblastoma tumorigenesis by down-regulating insulin-like growth factor-binding protein-3 (IGFBP3).
Q38802466MicroRNA-21 promotes proliferation, invasion and suppresses apoptosis in human osteosarcoma line MG63 through PTEN/Akt pathway
Q58184215MicroRNA-21 promotes the proliferation and invasion of cholesteatoma keratinocytes
Q47159666MicroRNA-21 regulates Osteogenic Differentiation of Periodontal Ligament Stem Cells by targeting Smad5.
Q41412753MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells.
Q36580732MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma
Q24633718MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4
Q37930520MicroRNA-21: a ubiquitously expressed pro-survival factor in cancer and other diseases
Q36725131MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1 (RASA1).
Q34211970MicroRNA-34a inhibits the proliferation and metastasis of osteosarcoma cells both in vitro and in vivo
Q36580396MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis
Q44718219MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor.
Q36215852MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells
Q64915473MicroRNA-Based Diagnosis and Treatment of Metastatic Human Osteosarcoma.
Q52590673MicroRNA-Mediated Regulation of HMGB1 in Human Hepatocellular Carcinoma.
Q50787878MicroRNA-Responsive Drug Release System for Selective Fluorescence Imaging and Photodynamic Therapy In Vivo.
Q93022677MicroRNA-based biomarkers for diagnosis of non-small cell lung cancer (NSCLC)
Q37941371MicroRNA-mediated breast cancer metastasis: from primary site to distant organs
Q86748477MicroRNA: A New Player for Cancer Chemoprevention
Q42004179MicroRNA: Biogenesis, Function and Role in Cancer
Q37828424MicroRNAs (miRNAs) in cancer invasion and metastasis: therapeutic approaches based on metastasis-related miRNAs
Q45873784MicroRNAs Reprogram Tumor Immune Response
Q38005062MicroRNAs and lung cancers: from pathogenesis to clinical implications
Q38064494MicroRNAs and lymphomagenesis: a functional review
Q38174308MicroRNAs and the cancer phenotype: profiling, signatures and clinical implications
Q21195211MicroRNAs and their target gene networks in breast cancer
Q26862716MicroRNAs and triple negative breast cancer
Q36553661MicroRNAs as potential biomarkers in human solid tumors
Q38011943MicroRNAs as putative mediators of treatment response in prostate cancer
Q47994022MicroRNAs in Breast Cancer: Diagnostic and Therapeutic Potential.
Q26823360MicroRNAs in breast cancer initiation and progression
Q38031835MicroRNAs in cancer treatment and prognosis.
Q37474280MicroRNAs in cancer: small molecules with a huge impact
Q37766206MicroRNAs in cardiac remodeling and disease
Q37894616MicroRNAs in colorectal cancer metastasis.
Q38215733MicroRNAs in human lung cancer.
Q34675280MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches.
Q35033659MicroRNAs in skin and wound healing.
Q83429939MicroRNAs--the micro steering wheel of tumour metastases
Q36262854MicroRNAs: Potential biomarkers in cancer
Q26853284MicroRNAs: regulators of cancer metastasis and epithelial-mesenchymal transition (EMT)
Q47811207MicroRNA‑141 inhibits epithelial‑mesenchymal transition, and ovarian cancer cell migration and invasion
Q38152548Microenvironmental regulation of cancer metastasis by miRNAs.
Q34674941Microvesicles derived from human umbilical cord Wharton's jelly mesenchymal stem cells attenuate bladder tumor cell growth in vitro and in vivo
Q36545873Migration-prone glioma cells show curcumin resistance associated with enhanced expression of miR-21 and invasion/anti-apoptosis-related proteins
Q42548474Mild two-step method to construct DNA-conjugated silicon nanoparticles: scaffolds for the detection of microRNA-21.
Q38632040Modeling miRNA-mRNA interactions that cause phenotypic abnormality in breast cancer patients.
Q34271727Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21.
Q30486511Molecular assays for the detection of microRNAs in prostate cancer
Q28273857Myc-modulated miR-9 makes more metastases
Q28543184NMR characterization of an oligonucleotide model of the miR-21 pre-element
Q37219999Negative regulation of lncRNA GAS5 by miR-21.
Q39453653New Insight into microRNA Functions in Cancer: Oncogene-microRNA-Tumor Suppressor Gene Network.
Q38034670New NSAID targets and derivatives for colorectal cancer chemoprevention.
Q38089079New biomarkers for lung cancer
Q21296770Next-generation sequencing of microRNAs for breast cancer detection
Q39001832Nicotine upregulates microRNA-21 and promotes TGF-β-dependent epithelial-mesenchymal transition of esophageal cancer cells
Q60958994Non-Coding RNAs in Breast Cancer: Intracellular and Intercellular Communication
Q94564507Non-coding RNAs as Putative Biomarkers of Cancer-Associated Cachexia
Q38667231Non-coding RNAs in Mammary Gland Development and Disease
Q33762263Non-coding RNAs: a key to future personalized molecular therapy?
Q37044600Noncanonical TGF-β signaling during mammary tumorigenesis
Q36571216Noncoding RNAs and Cancer.
Q26864697Noncoding RNAs in DNA repair and genome integrity
Q90183453Novel breast cancer screening: combined expression of miR-21 and MMP-1 in urinary exosomes detects 95% of breast cancer without metastasis
Q47239413Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level
Q26773316Oncogenic MicroRNAs: Key Players in Malignant Transformation
Q34130311OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.
Q37634314Oncoviruses and Pathogenic MicroRNAs in Humans
Q34618415Over-expression of miR-106b promotes cell migration and metastasis in hepatocellular carcinoma by activating epithelial-mesenchymal transition process
Q36756314Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse
Q44586187Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis
Q34025404PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease.
Q90287006PDCD4 Is an Androgen-Repressed Tumor Suppressor that Regulates Prostate Cancer Growth and Castration Resistance
Q39418925PDCD4 expression inversely correlated with miR-21 levels in gastric cancers
Q33738854PVT1-derived miR-1207-5p promotes breast cancer cell growth by targeting STAT6.
Q42865116Pathogenic mechanisms of deregulated microRNA expression in thyroid carcinomas of follicular origin
Q36165491Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion
Q41630132Placental Stem Villus Arterial Remodeling Associated with Reduced Hydrogen Sulfide Synthesis Contributes to Human Fetal Growth Restriction.
Q33572948Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression
Q30632163Polymer nanoparticles mediated codelivery of antimiR-10b and antimiR-21 for achieving triple negative breast cancer therapy.
Q53674278Post-transcriptional regulation by microrna-21 and let-7a microRNA in paediatric cholesteatoma.
Q33778961Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations
Q35376154Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation.
Q37902246Prognostic, therapeutic and diagnostic potential of microRNAs in non-small cell lung cancer
Q34174271Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma
Q39150619Programmed cell death 4 mechanism of action: the model to be updated?
Q30557551Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance
Q37478933Progress in microRNA delivery
Q28394712RETRACTED ARTICLE: Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism
Q34075234RNA helicase DDX5 regulates microRNA expression and contributes to cytoskeletal reorganization in basal breast cancer cells
Q39424688Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells
Q35754831Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs)
Q38161355Recent Advance in Biosensors for microRNAs Detection in Cancer
Q38449526Recent advances of microRNA-based molecular diagnostics to reduce false-positive lung cancer imaging
Q91714772Recognizing and stabilizing miR-21 by chiral ruthenium(II) complexes
Q34283673Redefining high-risk patients with stage II colon cancer by risk index and microRNA-21: results from a population-based cohort
Q36715870Reduced cystathionine γ-lyase and increased miR-21 expression are associated with increased vascular resistance in growth-restricted pregnancies: hydrogen sulfide as a placental vasodilator.
Q39756001Regulating A549 cells growth by ASO inhibiting miRNA expression
Q37895431Regulation and function of miRNA-21 in health and disease.
Q37259128Regulation of breast cancer and bone metastasis by microRNAs
Q38068926Regulation of breast cancer tumorigenesis and metastasis by miRNAs
Q35034340Regulation of cancer metastasis by cell-free miRNAs
Q37688816Regulation of gene expression by microRNA in HCV infection and HCV-mediated hepatocellular carcinoma
Q37148392Regulation of miR-19 to breast cancer chemoresistance through targeting PTEN
Q38191102Regulation of microRNAs in cancer metastasis.
Q34988330Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma
Q53257500Relationship between altered expression levels of MIR21, MIR143, MIR145, and MIR205 and clinicopathologic features of esophageal squamous cell carcinoma.
Q46040386Relationship between microRNA expression levels and histopathological features of dysplasia in oral leukoplakia.
Q35956619Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells
Q34525461Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway
Q37454682Review of MicroRNA Proposed Target Genes in Oral Cancer. Part II.
Q33694369Role of CSF-1 in progression of epithelial ovarian cancer
Q36205226Role of microRNA-21 and programmed cell death 4 in the pathogenesis of human uterine leiomyomas
Q36677690Role of microRNAs in breast cancer
Q57029561Rs4938723 Polymorphism Is Associated with Susceptibility to Hepatocellular Carcinoma Risk and Is a Protective Factor in Leukemia, Colorectal, and Esophageal Cancer
Q28941771SMAD proteins control DROSHA-mediated microRNA maturation
Q35757920STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation.
Q39665695STAT5 induces miR-21 expression in cutaneous T cell lymphoma.
Q92550520Scenario and future prospects of microRNAs in gastric cancer: A review
Q35562046Selective inhibition of miR-21 by phage display screened peptide
Q33728084Selective release of microRNA species from normal and malignant mammary epithelial cells
Q36317309Serum miR-21 level: a potential diagnostic and prognostic biomarker for non-small cell lung cancer
Q54322917Serum microRNA-21 is a novel biomarker in patients with esophageal squamous cell carcinoma.
Q35070602Shielding the messenger (RNA): microRNA-based anticancer therapies
Q35192383Side population cells of pancreatic cancer show characteristics of cancer stem cells responsible for resistance and metastasis
Q37133785Signal transduction in the development of pulmonary arterial hypertension
Q26827171Significance and therapeutic value of miRNAs in embryonal neural tumors
Q36768990Silibinin-Induced Apoptosis and Downregulation of MicroRNA-21 and MicroRNA-155 in MCF-7 Human Breast Cancer Cells
Q34425882Small players with big roles: microRNAs as targets to inhibit breast cancer progression
Q42170228Specific pomegranate juice components as potential inhibitors of prostate cancer metastasis
Q38849205Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis.
Q90975660Stopping transformed cancer cell growth by rigidity sensing
Q37796192Strategies to identify microRNA targets: New advances
Q38017601Stromal biomarkers in breast cancer development and progression
Q27653464Structural basis for translational inhibition by the tumour suppressor Pdcd4
Q36024500Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs
Q24647586Suppression of cell growth and invasion by miR-205 in breast cancer
Q33862088Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer
Q36490744Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology
Q34637817Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth
Q35008487Targeting miR-205 in breast cancer
Q38294147Technology in MicroRNA Profiling: Circulating MicroRNAs as Noninvasive Cancer Biomarkers in Breast Cancer
Q26830734The Akt-associated microRNAs
Q24657924The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo
Q39202332The Process and Regulatory Components of Inflammation in Brain Oncogenesis
Q38529935The Role of miR-21 in Cancer
Q49593660The Role of micro RNAs in Breast Cancer Metastasis: Preclinical Validation and Potential Therapeutic Targets
Q90471098The State of the Art on Blood MicroRNAs in Pancreatic Ductal Adenocarcinoma
Q36416030The Type I IFN-Induced miRNA, miR-21
Q39126198The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21.
Q36337417The association of microRNA expression with prognosis and progression in early-stage, non-small cell lung adenocarcinoma: a retrospective analysis of three cohorts.
Q28512635The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs
Q34220723The clinical potential of microRNAs
Q38694587The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer
Q37187237The complexity of microRNAs in human cancer
Q54997659The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform
Q30426792The elephant in the room: do microRNA-based therapies have a realistic chance of succeeding for brain tumors such as glioblastoma?
Q27022207The emerging molecular machinery and therapeutic targets of metastasis
Q34933986The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis
Q50496294The expression and clinical significance of circulating microRNA-21 in serum of five solid tumors.
Q39353707The first Keystone Symposia Conference on pulmonary vascular isease and right ventricular dysfunction: Current concepts and future therapies
Q37768337The function of microRNAs, small but potent molecules, in human prostate cancer.
Q24608778The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
Q38791765The miR-21/PTEN/Akt signaling pathway is involved in the anti-tumoral effects of zoledronic acid in human breast cancer cell lines.
Q38243969The miRNA network: micro-regulator of cell signaling in cancer
Q48682005The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer.
Q37638140The microRNA network and tumor metastasis
Q38170025The microRNA networks of TGFβ signaling in cancer
Q35123062The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death
Q35172895The oncogenic microRNA-21 inhibits the tumor suppressive activity of FBXO11 to promote tumorigenesis
Q37040558The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells
Q64104764The potential role of miR-126, miR-21 and miR-10b as prognostic biomarkers in renal cell carcinoma
Q33740551The real-time dynamic monitoring of microRNA function in cholangiocarcinoma
Q37766501The realm of microRNAs in cancers
Q37765520The role of MicroRNA in chemical carcinogenesis
Q38221290The role of miRNAs in cancer: from pathogenesis to therapeutic implications
Q34209973The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma
Q36396579The role of microRNAs in breast cancer migration, invasion and metastasis
Q36096641The role of microRNAs in colorectal cancer
Q37601781The role of microRNAs in endometriosis and associated reproductive conditions
Q35816884The roles of microRNAs in the regulation of tumor metastasis
Q37693586The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer.
Q37438657The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation
Q47701015Therapeutic impacts of microRNAs in breast cancer by their roles in regulating processes involved in this disease
Q33780722Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
Q28395179Therapeutic use of microRNAs in lung cancer
Q37822465Tissular and soluble miRNAs for diagnostic and therapy improvement in digestive tract cancers
Q92164237ToGo-WF: prediction of RNA tertiary structures and RNA-RNA/protein interactions using the KNIME workflow
Q35131885Transfer of microRNAs by extracellular membrane microvesicles: a nascent crosstalk model in tumor pathogenesis, especially tumor cell-microenvironment interactions
Q92711379Transregulation of microRNA miR-21 promoter by AP-1 transcription factor in cervical cancer cells
Q39449941Triggering of Toll-like receptor 4 on metastatic breast cancer cells promotes αvβ3-mediated adhesion and invasive migration
Q64927427Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma.
Q36275252Tropomyosin-1 acts as a potential tumor suppressor in human oral squamous cell carcinoma
Q55094502Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma.
Q37548937Tumor dormancy and metastasis.
Q33753966Ubc9 promotes breast cell invasion and metastasis in a sumoylation-independent manner
Q34998769Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma
Q40447202Up-Regulation of miR-21 Expression Predicate Advanced Clinicopathological Features and Poor Prognosis in Patients with Non-Small Cell Lung Cancer.
Q37258559Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.
Q34998307Up-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancer
Q53309914Up-regulation of microRNA in bladder tumor tissue is not common.
Q41390518Wound fluids affect miR-21, miR-155 and miR-221 expression in breast cancer cell lines, and this effect is partially abrogated by intraoperative radiation therapy treatment
Q38342516hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations
Q34316535miR-10b is overexpressed in hepatocellular carcinoma and promotes cell proliferation, migration and invasion through RhoC, uPAR and MMPs
Q33966873miR-10b targets Tiam1: implications for Rac activation and carcinoma migration
Q37448717miR-139-5p is a regulator of metastatic pathways in breast cancer
Q89948121miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells
Q24634704miR-145-mediated suppression of cell growth, invasion and metastasis
Q28275238miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway
Q28283590miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1
Q33625493miR-183 inhibits TGF-beta1-induced apoptosis by downregulation of PDCD4 expression in human hepatocellular carcinoma cells
Q39436512miR-1915 inhibits Bcl-2 to modulate multidrug resistance by increasing drug-sensitivity in human colorectal carcinoma cells
Q21091183miR-200 enhances mouse breast cancer cell colonization to form distant metastases
Q55617722miR-204 functions as a tumor suppressor gene, at least partly by suppressing CYP27A1 in glioblastoma.
Q35262736miR-21 and miR-155 are associated with mitotic activity and lesion depth of borderline melanocytic lesions
Q54280971miR-21 downregulated TCF21 to inhibit KISS1 in renal cancer.
Q34288764miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer
Q33898669miR-21 inhibitor suppresses proliferation and migration of nasopharyngeal carcinoma cells through down-regulation of BCL2 expression
Q34285397miR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer
Q38835514miR-21 regulates tumor progression through the miR-21-PDCD4-Stat3 pathway in human salivary adenoid cystic carcinoma
Q36369267miR-21 synergizes with BMP9 in osteogenic differentiation by activating the BMP9/Smad signaling pathway in murine multilineage cells
Q39483435miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells
Q34931601miR-21: a small multi-faceted RNA.
Q39749407miR-21: an oncomir on strike in prostate cancer.
Q39335411miR-297 modulates multidrug resistance in human colorectal carcinoma by down-regulating MRP-2.
Q34179800miR-29a suppresses growth and invasion of gastric cancer cells in vitro by targeting VEGF-A.
Q35191816miR-29a/b enhances cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC and COL3A1 gene expression
Q39917967miR-31: a master regulator of metastasis?
Q34787462miR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and interleukin-8
Q24613599miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
Q34771896miRNA Biomarkers in Breast Cancer Detection and Management
Q34215056miRNA as potential biomarkers of breast cancer in the Lebanese population and in young women: a pilot study
Q38186130miRNA expression profiles associated with diagnosis and prognosis in lung cancer
Q37643542miRNA-21 as a novel therapeutic target in lung cancer
Q26747138miRNAs Signature in Head and Neck Squamous Cell Carcinoma Metastasis: A Literature Review
Q37750843miRNAs as molecular biomarkers of cancer
Q26824561miRNAs in breast cancer tumorigenesis (Review)
Q92208779miRNA‑30a‑3p inhibits metastasis and enhances radiosensitivity in esophageal carcinoma by targeting insulin‑like growth factor 1 receptor
Q33629095microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells
Q28264087microRNA involvement in human cancer
Q38021509microRNA regulation of cell viability and drug sensitivity in lung cancer
Q33703585microRNA, cell cycle, and human breast cancer
Q36642611microRNA-1301-mediated inhibition of tumorigenesis
Q36424194microRNA-21 overexpression contributes to cell proliferation by targeting PTEN in endometrioid endometrial cancer
Q37587348microRNA-21 promotes cardiac fibrosis and development of heart failure with preserved left ventricular ejection fraction by up-regulating Bcl-2.
Q34257789microRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt-IKKβ-mTORC1 axis to regulate renal cancer cell invasion
Q37760459microRNAs and EMT in mammary cells and breast cancer.
Q50544691microRNAs and Endometrial Pathophysiology.
Q35185340microRNAs, Gap Junctional Intercellular Communication and Mesenchymal Stem Cells in Breast Cancer Metastasis
Q37784515microRNAs: Master Regulators as Potential Therapeutics in Cancer
Q34832663microRNAs: short non-coding bullets of gain of function mutant p53 proteins

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