MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN

scientific article (publication date: 15 January 2008)

MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/0008-5472.CAN-07-2488
P8608Fatcat IDrelease_fwgbhwugijag7iy63qyamvi3lq
P3181OpenCitations bibliographic resource ID1548992
P698PubMed publication ID18199536
P5875ResearchGate publication ID5651066

P2093author name stringWang J
Yang H
He L
Coppola D
Nicosia SV
Kruk PA
Cheng JQ
Kong W
Zhao JJ
O'Donnell JD
Wenham RM
P2860cites workAKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistanceQ47971254
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
cisplatinQ412415
microRNA expressionQ60681249
P304page(s)425-33
P577publication date2008-01-15
P1433published inCancer ResearchQ326097
P1476titleMicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN
P478volume68

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cites work (P2860)
Q26746952A Comparative Analysis of Genetic and Epigenetic Events of Breast and Ovarian Cancer Related to Tumorigenesis
Q34072975A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk
Q38637596A Macro View of MicroRNAs: The Discovery of MicroRNAs and Their Role in Hematopoiesis and Hematologic Disease
Q37529831A Pilot Study of Circulating MicroRNA-125b as a Diagnostic and Prognostic Biomarker for Epithelial Ovarian Cancer
Q24632651A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
Q83575970A commentary on MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma
Q35547227A computational approach to identifying gene-microRNA modules in cancer
Q33634277A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer
Q34985302A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer
Q34167137A microRNA survival signature (MiSS) for advanced ovarian cancer.
Q51354687A simple method for incorporating dynamic effects of intronic miRNA mediated regulation.
Q36074982Aberrant expression of microRNAs in gastric cancer and biological significance of miR-574-3p
Q37124069Adenomatous polyposis coli (APC) regulates miR17-92 cluster through β-catenin pathway in colorectal cancer
Q37386222Advances in circulating microRNAs as diagnostic and prognostic markers for ovarian cancer
Q39501335Alterations of microRNAs in cisplatin-resistant human non-small cell lung cancer cells (A549/DDP).
Q24648360Altered microRNA Expression Patterns in Hepatoblastoma Patients
Q47838011Altered microRNA expression patterns during the initiation and promotion stages of neonatal diethylstilbestrol-induced dysplasia/neoplasia in the hamster (Mesocricetus auratus) uterus
Q36944254An array-based analysis of microRNA expression comparing matched frozen and formalin-fixed paraffin-embedded human tissue samples
Q39400566An electrochemical signal 'off-on' sensing platform for microRNA detection
Q38060281An emerging role for microRNAs in NF1 tumorigenesis
Q35477129An integrated network of microRNA and gene expression in ovarian cancer
Q35672216An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription
Q98164950Analysis of conserved miRNAs in cynomolgus macaque genome using small RNA sequencing and homology searching
Q34365873Annexin A4 induces platinum resistance in a chloride-and calcium-dependent manner
Q35574298Anti-fibrotic Role of miR-214 in Thioacetamide-induced Liver Cirrhosis in Rats
Q99551767Antitumor effects and molecular mechanisms of action of natural products in ovarian cancer
Q37783931Approaches and limitations of phosphatidylinositol-3-kinase pathway activation status as a predictive biomarker in the clinical development of targeted therapy
Q36590184Blood microRNAs in low or no risk ischemic stroke patients
Q35273614By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy.
Q37372564CHO microRNA engineering is growing up: recent successes and future challenges
Q37152727Candidate microRNA biomarkers in human epithelial ovarian cancer: systematic review profiling studies and experimental validation
Q34391443Cardio-miRNAs and onco-miRNAs: circulating miRNA-based diagnostics for non-cancerous and cancerous diseases
Q37316664Cell-Free microRNA-214 From Urine as a Biomarker for Non-Muscle-Invasive Bladder Cancer.
Q34089685Cellular Responses to Cisplatin‐Induced DNA Damage
Q38206278Cellular communication via microparticles: role in transfer of multidrug resistance in cancer
Q34055428Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53
Q21245716Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy
Q45077649Characterization of disease progression in ovarian cancer by utilizing 'chemograms' of ovarian cancer stem cells
Q38490114Circulating MicroRNAs as potential biomarkers for alcoholic steatohepatitis
Q35562931Circulating microRNAs as potential biomarkers for endometriosis
Q36105474Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes
Q35735278Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer.
Q35204609Clinically relevant microRNAs in ovarian cancer
Q35904981Clinico-Pathological Association of Delineated miRNAs in Uveal Melanoma with Monosomy 3/Disomy 3 Chromosomal Aberrations
Q35116221Clinicopathological significance of microRNA-214 in gastric cancer and its effect on cell biological behaviour
Q39218148Comparative study of microRNA regulation on FOXL2 between adult-type and juvenile-type granulosa cell tumours in vitro.
Q55385529Comparative transcriptome analysis to investigate the potential role of miRNAs in milk protein/fat quality.
Q37097112Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance
Q86506652Computational approaches for identifying cancer miRNA expressions
Q33492595Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers
Q35010110Control of the rescue and replication of Semliki Forest virus recombinants by the insertion of miRNA target sequences
Q89529824Cooperation between SS18-SSX1 and miR-214 in Synovial Sarcoma Development and Progression
Q36350416Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma.
Q34416068Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten.
Q37195490Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions
Q51442271Crosstalk between the vitamin D receptor (VDR) and miR-214 in regulating SuFu, a hedgehog pathway inhibitor in breast cancer cells.
Q38717405Curcumin suppresses cisplatin resistance development partly via modulating extracellular vesicle-mediated transfer of MEG3 and miR-214 in ovarian cancer
Q36517492Current status and implications of microRNAs in ovarian cancer diagnosis and therapy
Q38711390Current status on microRNAs as biomarkers for ovarian cancer
Q35774040DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression
Q34321166Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) in human peripheral blood mononuclear cells
Q37305438Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy
Q36553118Deregulation of miR-21 and miR-155 and their putative targets after silibinin treatment in T47D breast cancer cells
Q41837402Deregulation of the miRNAs expression in cervical cancer: human papillomavirus implications
Q47593475Diagnostic and Prognostic Biomarkers in ovarian cancer and the potential roles of cancer stem cells - An updated review
Q53659259Diagnostic potential of PTEN-targeting miR-214 in the blood of breast cancer patients.
Q38928861Direct detection of microRNA based on plasmon hybridization of nanoparticle dimers
Q46314432Distinctive microRNA expression signatures in proton-irradiated mice
Q35377371Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia
Q39521543Down-regulated miRNA-214 induces a cell cycle G1 arrest in gastric cancer cells by up-regulating the PTEN protein
Q33677872Down-regulation of miR-214 reverses erlotinib resistance in non-small-cell lung cancer through up-regulating LHX6 expression.
Q24655144Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1
Q37364111Downregulated miR-506 expression facilitates pancreatic cancer progression and chemoresistance via SPHK1/Akt/NF-κB signaling.
Q52676612Downregulation of MicroRNA-455-3p Links to Proliferation and Drug Resistance of Pancreatic Cancer Cells via Targeting TAZ.
Q39074816Downregulation of miR-130a contributes to cisplatin resistance in ovarian cancer cells by targeting X-linked inhibitor of apoptosis (XIAP) directly
Q38699390Downregulation of miR-193a-3p inhibits cell growth and migration in renal cell carcinoma by targeting PTEN.
Q39809297Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer
Q44104084Downregulation of miR-195 correlates with lymph node metastasis and poor prognosis in colorectal cancer
Q39117322Downregulation of miR-29 contributes to cisplatin resistance of ovarian cancer cells
Q38712331Downregulation of miR-33a-5p in Hepatocellular Carcinoma: A Possible Mechanism for Chemotherapy Resistance
Q34806765Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis.
Q90465480Dysregulated microRNA expression profiles in gastric cancer cells with high peritoneal metastatic potential
Q39735817Dysregulation of kallikrein-related peptidases in renal cell carcinoma: potential targets of miRNAs
Q37040599Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer
Q21198870Dysregulation of miR-15a and miR-214 in human pancreatic cancer
Q41034799Dysregulation of microRNA-214 and PTEN contributes to the pathogenesis of hypoxic pulmonary hypertension
Q52331347ELLPMDA: Ensemble Learning and Link Prediction for miRNA-Disease Association prediction.
Q26781912EMT-Inducing Molecular Factors in Gynecological Cancers
Q34168267ER stress negatively modulates the expression of the miR-199a/214 cluster to regulates tumor survival and progression in human hepatocellular cancer
Q36520143Early detection biomarkers for ovarian cancer
Q42722759Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells
Q92945442Effects of miR-34b/miR-892a Upregulation and Inhibition of ABCB1/ABCB4 on Melatonin-Induced Apoptosis in VCR-Resistant Oral Cancer Cells
Q90636051Efficient miRNA Inhibitor Delivery with Graphene Oxide-Polyethylenimine to Inhibit Oral Squamous Cell Carcinoma
Q98238826Efficient miRNA Inhibitor with GO-PEI Nanosheets for Osteosarcoma Suppression by Targeting PTEN
Q33621526Elevated expression of TMEM205, a hypothetical membrane protein, is associated with cisplatin resistance
Q34526484Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer
Q42176783Elucidating the mechanism of miRNA-214 in the regulation of gingival carcinoma
Q39123447Enrichment of ovarian cancer stem-like cells is associated with epithelial to mesenchymal transition through an miRNA-activated AKT pathway
Q90682389Epigenetic Biomarkers in the Management of Ovarian Cancer: Current Prospectives
Q51168142Epigenetic Downregulation of PTEN in Gallbladder Cancer.
Q33615837Epigenetic control of autophagy by microRNAs in ovarian cancer
Q37853945Epigenetic markers for chemosensitivity and chemoresistance in pancreatic cancer--a review
Q38544386Epigenetic mechanisms and therapeutic targets of chemotherapy resistance in epithelial ovarian cancer
Q34874813Epigenetic regulation of cancer-associated genes in ovarian cancer
Q38730550Epigenetic silencing of miR-137 induces drug resistance and chromosomal instability by targeting AURKA in multiple myeloma
Q33572313Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer
Q34305438Epigenetic therapies as a promising strategy for overcoming chemoresistance in epithelial ovarian cancer
Q90266694Epigenetically altered miR‑193a‑3p promotes HER2 positive breast cancer aggressiveness by targeting GRB7
Q37737449Epigenetics of ovarian cancer: from the lab to the clinic
Q35636575Epigenomics and ovarian carcinoma.
Q35711392Epigenomics of ovarian cancer and its chemoprevention
Q36923079Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2.
Q33561359Evaluation of Plasma MicroRNAs as Diagnostic and Prognostic Biomarkers in Pancreatic Adenocarcinoma: miR-196a and miR-210 Could Be Negative and Positive Prognostic Markers, Respectively
Q33980036Evidence for the complexity of microRNA-mediated regulation in ovarian cancer: a systems approach.
Q81549199Exosomal microRNAs step into the biomarker arena
Q49886928Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer
Q93369514Exposure of the extracellular matrix and colonization of the ovary in metastasis of fallopian-tube-derived cancer
Q38996872Expression of serum miR-200a, miR-200b, and miR-200c as candidate biomarkers in epithelial ovarian cancer and their association with clinicopathological features
Q37356540FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
Q24610158Flexible and versatile as a chameleon-sophisticated functions of microRNA-199a
Q26797287Focus on PTEN Regulation
Q34450467Follicular dendritic cell-dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion-mediated Bim down-regulation through induction of microRNA-181a
Q33658229Frequent downregulation of miR-34 family in human ovarian cancers
Q38228678From miRNA regulation to miRNA-TF co-regulation: computational approaches and challenges
Q38951546Functional analysis of miR-34c as a putative tumor suppressor in high-grade serous ovarian cancer
Q41082813Functional screen analysis reveals miR-3142 as central regulator in chemoresistance and proliferation through activation of the PTEN-AKT pathway in CML.
Q34669761Gain-of-function microRNA screens identify miR-193a regulating proliferation and apoptosis in epithelial ovarian cancer cells
Q33433032Gemcitabine Plus Vinorelbine as Second-Line Therapy in Patients With Metastatic Esophageal Cancer Previously Treated With Platinum-Based Chemotherapy
Q34252833Gene regulation is governed by a core network in hepatocellular carcinoma.
Q50059680Genetic ablation of Rbm38 promotes lymphomagenesis in the context of mutant p53 by downregulating PTEN.
Q26769604Genetic and epigenetic heterogeneity of epithelial ovarian cancer and the clinical implications for molecular targeted therapy
Q34227531Genetic polymorphisms in pre-microRNA genes as prognostic markers of colorectal cancer
Q37730044Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response
Q38256465Genomic alterations as mediators of miRNA dysregulation in ovarian cancer.
Q36657641Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer
Q47171648Ginsenoside Rg3 Decreases Fibrotic and Invasive Nature of Endometriosis by Modulating miRNA-27b: In Vitro and In Vivo Studies
Q47646794Global DNA methylation analysis reveals miR-214-3p contributes to cisplatin resistance in pediatric intracranial nongerminomatous malignant germ cell tumors
Q28478564Global analysis of DNA methylation by Methyl-Capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell
Q35089974Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker
Q47385628HDAC inhibitor suppresses proliferation and invasion of breast cancer cells through regulation of miR-200c targeting CRKL.
Q34115364HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway
Q92616938HOTAIR/miR-214-3p/FLOT1 axis plays an essential role in the proliferation, migration, and invasion of hepatocellular carcinoma
Q36242420High Throughput Sequencing of Extracellular RNA from Human Plasma
Q92288085High expression of NFAT2 contributes to carboplatin resistance in lung cancer
Q35105646High expression of miR-214 is associated with a worse disease-specific survival of the triple-negative breast cancer patients.
Q37337788High fat diet induced obesity alters ovarian phosphatidylinositol-3 kinase signaling gene expression
Q28476426Holoclone forming cells from pancreatic cancer cells enrich tumor initiating cells and represent a novel model for study of cancer stem cells
Q24321272Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells
Q38857270Hybrid-polymerase chain reaction to identify novel target genes of miR-134 in paclitaxel resistant human ovarian carcinoma cells
Q33504873Identification and characterization of miRNAs expressed in the bovine ovary
Q37006170Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
Q37215410Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver Fibrosis.
Q35326035Identification of a microRNA signature in renal fibrosis: role of miR-21.
Q34069581Identification of a microRNA signature of renal ischemia reperfusion injury
Q35744525Identification of a novel miRNA from the ovine ovary by a combinatorial approach of bioinformatics and experiments
Q42276827Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets
Q54962236Identification of core aberrantly expressed microRNAs in serous ovarian carcinoma.
Q35767380Identification of links between small molecules and miRNAs in human cancers based on transcriptional responses
Q34838128Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis
Q39137785Identification of microRNAs and mRNAs associated with multidrug resistance of human laryngeal cancer Hep-2 cells
Q34368313Identifying functional miRNA-mRNA regulatory modules with correspondence latent dirichlet allocation
Q37497803Identifying miRNAs, targets and functions.
Q21199589Identifying microRNA/mRNA dysregulations in ovarian cancer
Q34366411Identifying multi-layer gene regulatory modules from multi-dimensional genomic data
Q27016123Impact of Nutrition on Non-Coding RNA Epigenetics in Breast and Gynecological Cancer
Q28539562Impact of ketamine on learning and memory function, neuronal apoptosis and its potential association with miR-214 and PTEN in adolescent rats
Q33903223Implication of microRNAs in drug resistance for designing novel cancer therapy
Q39304895Induction of microRNA-214-5p in human and rodent liver fibrosis
Q91761695Inhibition of miR-214-3p Aids in Preventing Epithelial Ovarian Cancer Malignancy by Increasing the Expression of LHX6
Q38858897Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice
Q36755634Inhibition of p38 mitogen-activated protein kinase alters microRNA expression and reverses epithelial-to-mesenchymal transition
Q42723115Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma
Q38152325Involvement of autophagy in cervical, endometrial and ovarian cancer
Q21198790Involvement of autophagy in ovarian cancer: a working hypothesis
Q39615360Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line
Q39371337Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells
Q55038905Involvement of non-coding RNAs in chemotherapy resistance of ovarian cancer.
Q28486480Klotho sensitizes human lung cancer cell line to cisplatin via PI3k/Akt pathway
Q37500162Knockdown of miR-214 promotes apoptosis and inhibits cell proliferation in nasopharyngeal carcinoma
Q34360216LOH at 6q and 10q in fractionated circulating DNA of ovarian cancer patients is predictive for tumor cell spread and overall survival
Q24653755Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression
Q93002451Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer
Q39134240Let-7b expression determines response to chemotherapy through the regulation of cyclin D1 in glioblastoma
Q38267349Light-regulated microRNAs
Q58804953LncRNA PVT1 promotes ovarian cancer progression by silencing miR-214
Q92795407Long Non-Coding RNA NONHSAT076754 Promotes Invasion and Metastasis in Epithelial Ovarian Cancer
Q35172618Long non-coding RNAs (LncRNA) regulated by transforming growth factor (TGF) β: LncRNA-hit-mediated TGFβ-induced epithelial to mesenchymal transition in mammary epithelia
Q37636621Loss of MYC and E-box3 binding contributes to defective MYC-mediated transcriptional suppression of human MC-let-7a-1~let-7d in glioblastoma
Q93048655Loss of PTEN in Fallopian Tube Epithelium Results in Multicellular Tumor Spheroid Formation and Metastasis to the Ovary
Q84079294Loss of heterozygosity proximal to the M6P/IGF2R locus is predictive for the presence of disseminated tumor cells in the bone marrow of ovarian cancer patients before and after chemotherapy
Q89641392Loss of phosphatase activity in PTEN (phosphatase and tensin homolog deleted on chromosome ten) results in endometrial carcinoma in humans: An in-silico study
Q50859800Meta-analysis of transcriptome reveals let-7b as an unfavorable prognostic biomarker and predicts molecular and clinical subclasses in high-grade serous ovarian carcinoma.
Q37806613Metastamirs: a stepping stone towards improved cancer management
Q39675974MiR-125b targets BCL3 and suppresses ovarian cancer proliferation
Q37584834MiR-1307 promotes ovarian cancer cell chemoresistance by targeting the ING5 expression
Q38359431MiR-139-5p: promising biomarker for cancer
Q39210882MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine
Q24632636MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer
Q91876236MiR-186 bidirectionally regulates cisplatin sensitivity of ovarian cancer cells via suppressing targets PIK3R3 and PTEN and upregulating APAF1 expression
Q35854007MiR-191 inhibits TNF-α induced apoptosis of ovarian endometriosis and endometrioid carcinoma cells by targeting DAPK1.
Q47569619MiR-199a suppresses prostate cancer paclitaxel resistance by targeting YES1.
Q33688560MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis
Q41549238MiR-214 inhibits cell migration, invasion and promotes the drug sensitivity in human cervical cancer by targeting FOXM1
Q28569223MiR-214 promotes the alcohol-induced oxidative stress via down-regulation of glutathione reductase and cytochrome P450 oxidoreductase in liver cells
Q37028111MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN.
Q64092312MiR-214 sensitizes human colon cancer cells to 5-FU by targeting Hsp27
Q38807890MiR-214 suppressed ovarian cancer and negatively regulated semaphorin 4D.
Q34409807MiR-214 targets β-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma.
Q38940572MiR-218 regulates cisplatin chemosensitivity in breast cancer by targeting BRCA1.
Q37045562MiR-24 enhances radiosensitivity in nasopharyngeal carcinoma by targeting SP1.
Q39681268MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells
Q41926584MiR-3120 is a mirror microRNA that targets heat shock cognate protein 70 and auxilin messenger RNAs and regulates clathrin vesicle uncoating
Q37301794MiR-320a inhibits gastric carcinoma by targeting activity in the FoxM1-P27KIP1 axis
Q36413483MiR-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR/P70S6K1
Q37729740MiR-519d represses ovarian cancer cell proliferation and enhances cisplatin-mediated cytotoxicity in vitro by targeting XIAP.
Q38996307MiR-718 represses VEGF and inhibits ovarian cancer cell progression
Q34036679MiRNA as potential biomarkers and therapeutic targets for gastric cancer.
Q45942073MiRNA expression signature for potentially predicting the prognosis of ovarian serous carcinoma.
Q39413698MiRNA-21: a biomarker predictive for platinum-based adjuvant chemotherapy response in patients with non-small cell lung cancer
Q36685095MiRNA-429 suppresses the growth of gastric cancer cells in vitro
Q34808577MiRNAs as Biomarkers for Management of Patients With Colorectal Cancer
Q37297742MiRNAs which target CD3 subunits could be potential biomarkers for cancers
Q38905681MiRNAs-mediated cisplatin resistance in breast cancer
Q35223019Micro-RNA378 (miR-378) regulates ovarian estradiol production by targeting aromatase
Q38183485Micro-RNAs and ovarian cancer: the state of art and perspectives of clinical research
Q27005811Micro-RNAs as potential new molecular biomarkers in oncology: have they reached relevance for the clinical imaging sciences?
Q37981156MicroRNA Control of Invasion and Metastasis Pathways
Q92876704MicroRNA Signature in Human Normal and Tumoral Neural Stem Cells
Q37295059MicroRNA and cancer--focus on apoptosis
Q37751868MicroRNA and drug resistance
Q35631669MicroRNA changes in human arterial endothelial cells with senescence: relation to apoptosis, eNOS and inflammation.
Q33344505MicroRNA expression and identification of putative miRNA targets in ovarian cancer
Q36253778MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features
Q50014321MicroRNA expression profiles in non‑epithelial ovarian tumors.
Q39544815MicroRNA expression profiles of head and neck squamous cell carcinoma with docetaxel-induced multidrug resistance
Q53280271MicroRNA expression profiling is a potential diagnostic tool for thyroid cancer.
Q38336334MicroRNA fate upon targeting with anti-miRNA oligonucleotides as revealed by an improved Northern-blot-based method for miRNA detection.
Q35908632MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers
Q64883178MicroRNA in Ovarian Cancer: Biology, Pathogenesis, and Therapeutic Opportunities.
Q35055772MicroRNA in the ovary and female reproductive tract
Q24649254MicroRNA miR-155 is a biomarker of early pancreatic neoplasia
Q36318784MicroRNA miR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog
Q37388413MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer
Q34694027MicroRNA profile of paclitaxel-resistant serous ovarian carcinoma based on formalin-fixed paraffin-embedded samples
Q33508232MicroRNA profiling of BRCA1/2 mutation-carrying and non-mutation-carrying high-grade serous carcinomas of ovary
Q35064852MicroRNA profiling reveals that miR-21, miR486 and miR-214 are upregulated and involved in cell survival in Sézary syndrome
Q27003271MicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and development
Q35487297MicroRNA signature of cis-platin resistant vs. cis-platin sensitive ovarian cancer cell lines
Q29614237MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
Q39494676MicroRNA-101 inhibits growth of epithelial ovarian cancer by relieving chromatin-mediated transcriptional repression of p21(waf¹/cip¹).
Q35523881MicroRNA-125b potentiates macrophage activation
Q37625750MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway
Q54284943MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN.
Q24648090MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA
Q53205827MicroRNA-155 promotes apoptosis in SKOV3, A2780, and primary cultured ovarian cancer cells.
Q24603354MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer
Q33917538MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression
Q39067776MicroRNA-181a enhances the chemoresistance of human cervical squamous cell carcinoma to cisplatin by targeting PRKCD.
Q55418376MicroRNA-19b promotes the migration and invasion of ovarian cancer cells by inhibiting the PTEN/AKT signaling pathway.
Q42367922MicroRNA-205-5p regulates the chemotherapeutic resistance of hepatocellular carcinoma cells by targeting PTEN/JNK/ANXA3 pathway
Q34436329MicroRNA-20b promotes cell growth of breast cancer cells partly via targeting phosphatase and tensin homologue (PTEN).
Q64233019MicroRNA-20b promotes proliferation of H22 hepatocellular carcinoma cells by targeting PTEN
Q38737099MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer
Q28115504MicroRNA-214 Is Upregulated in Heart Failure Patients and Suppresses XBP1-Mediated Endothelial Cells Angiogenesis
Q36392780MicroRNA-214 Mediates Isoproterenol-induced Proliferation and Collagen Synthesis in Cardiac Fibroblasts
Q37078685MicroRNA-214 Reduces Insulin-like Growth Factor-1 (IGF-1) Receptor Expression and Downstream mTORC1 Signaling in Renal Carcinoma Cells
Q47887382MicroRNA-214 protects cardiac myocytes against H2O2-induced injury
Q35922278MicroRNA-214 suppresses growth and invasiveness of cervical cancer cells by targeting UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7.
Q38751258MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells
Q36336233MicroRNA-214 suppresses the proliferation of human hepatocellular carcinoma cells by targeting E2F3.
Q24597730MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
Q24648241MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
Q24645663MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
Q38858232MicroRNA-222 promotes human non-small cell lung cancer H460 growth by targeting p27.
Q36304803MicroRNA-26b Modulates the NF-κB Pathway in Alveolar Macrophages by Regulating PTEN.
Q33843200MicroRNA-382 induced by HIF-1α is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog
Q35441996MicroRNA-383 regulates the apoptosis of tumor cells through targeting Gadd45g
Q57786973MicroRNA-423 promotes proliferation, migration and invasion and induces chemoresistance of endometrial cancer cells
Q38960629MicroRNA-449a reduces cell survival and enhances cisplatin-induced cytotoxicity via downregulation of NOTCH1 in ovarian cancer cells
Q89475347MicroRNA-498 promotes proliferation and migration by targeting the tumor suppressor PTEN in breast cancer cells
Q100477224MicroRNA-572/hMOF/Sirt6 regulates the progression of ovarian cancer
Q36394758MicroRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma
Q37377527MicroRNA-Mediated Down-Regulation of Apoptosis Signal-Regulating Kinase 1 (ASK1) Attenuates the Apoptosis of Human Mesenchymal Stem Cells (MSCs) Transplanted into Infarcted Heart
Q33764106MicroRNA-mRNA functional pairs for cisplatin resistance in ovarian cancer cells
Q39382756MicroRNA-mediated drug resistance in ovarian cancer
Q35207545MicroRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development
Q26822743MicroRNA: a new and promising potential biomarker for diagnosis and prognosis of ovarian cancer
Q38172970MicroRNA: a prognostic biomarker and a possible druggable target for circumventing multidrug resistance in cancer chemotherapy
Q33809305MicroRNAs MiR-17, MiR-20a, and MiR-106b act in concert to modulate E2F activity on cell cycle arrest during neuronal lineage differentiation of USSC.
Q36602853MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies
Q45944835MicroRNAs and complex diseases: from experimental results to computational models.
Q38174308MicroRNAs and the cancer phenotype: profiling, signatures and clinical implications
Q37722649MicroRNAs and their role in gynecological tumors
Q94046968MicroRNAs as Key Regulators of Ovarian Cancers
Q37432291MicroRNAs couple cell fate and developmental timing in retina
Q58923813MicroRNAs in Cancer Drug Resistance and Drug Sensitivity
Q35832148MicroRNAs in apoptosis, autophagy and necroptosis
Q26823360MicroRNAs in breast cancer initiation and progression
Q38223219MicroRNAs in cancer stem cells: current status and future directions
Q39333266MicroRNAs in gynecological cancers: Small molecules with big implications
Q33796565MicroRNAs in ovarian carcinomas
Q38003048MicroRNAs in pancreatic cancer metabolism
Q39950193MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease
Q38086010MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells
Q24618771MicroRNAs: control and loss of control in human physiology and disease
Q35673637MicroRNAs: short non-coding players in cancer chemoresistance.
Q92582088MicroRNA‑214 suppresses the viability, migration and invasion of human colorectal carcinoma cells via targeting transglutaminase 2
Q93111083MicroRNA‑608 sensitizes non‑small cell lung cancer cells to cisplatin by targeting TEAD2
Q64234430Micromanaging aerobic respiration and glycolysis in cancer cells
Q34108602Micromarkers: miRNAs in cancer diagnosis and prognosis.
Q23916204Microprocessor of microRNAs: regulation and potential for therapeutic intervention
Q35135678Minireview: The roles of small RNA pathways in reproductive medicine
Q37328836Minireview: epigenetic changes in ovarian cancer.
Q42215256Modulation of chemoresponsiveness to platinum-based agents by microRNAs in cancer
Q38580177Molecular Regulation of Parturition: A Myometrial Perspective
Q35116008Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.
Q33718304Molecular characterization of aromatase inhibitor-resistant, tamoxifen-resistant and LTEDaro cell lines
Q38832323Molecular diagnosis and molecular profiling to detect treatment-resistant ovarian cancer
Q37702543Molecular epigenetics in the management of ovarian cancer: are we investigating a rational clinical promise?
Q37982453Molecular mechanisms of cisplatin resistance in bladder cancer.
Q48274587Molecular mechanisms of drug resistance in ovarian cancer.
Q34586019Multiple genetic alterations within the PI3K pathway are responsible for AKT activation in patients with ovarian carcinoma
Q36862768Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response
Q36908289Myocardial AKT: the omnipresent nexus
Q36390287NRP1 is targeted by miR-130a and miR-130b, and is associated with multidrug resistance in epithelial ovarian cancer based on integrated gene network analysis
Q31040165Network analysis of microRNAs and their regulation in human ovarian cancer
Q37725910New insights into the mechanisms of gastric cancer multidrug resistance and future perspectives
Q37837735New players in ovarian cancer
Q55237582Non-Coding Transcript Heterogeneity in Mesothelioma: Insights from Asbestos-Exposed Mice.
Q57815805Non-coding RNA NEAT1/miR-214-3p contribute to doxorubicin resistance of urothelial bladder cancer preliminary through the Wnt/β-catenin pathway
Q38885498Noncoding RNAs Regulating Cancer Signaling Network
Q36571216Noncoding RNAs and Cancer.
Q38885495Noncoding RNAs in Therapeutic Resistance of Cancer
Q96609205Noncoding RNAs: the shot callers in tumor immune escape
Q42218359Nongenomic Mechanisms of PTEN Regulation
Q36209417Novel classes of non-coding RNAs and cancer
Q39096424Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.
Q35837949Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways
Q48124146Ovarian Cancers: Genetic Abnormalities, Tumor Heterogeneity and Progression, Clonal Evolution and Cancer Stem Cells
Q38013671Ovarian cancer stem cells: elusive targets for chemotherapy
Q36540852Overexpression of miR-214-3p in esophageal squamous cancer cells enhances sensitivity to cisplatin by targeting survivin directly and indirectly through CUG-BP1.
Q50236474Overexpression of microRNA-15 increases the chemosensitivity of colon cancer cells to 5-fluorouracil and oxaliplatin by inhibiting the nuclear factor-κB signalling pathway and inducing apoptosis.
Q28396088Overexpression of secretagogin inhibits cell apoptosis and induces chemoresistance in small cell lung cancer under the regulation of miR-494
Q28383083PI3K/PTEN signaling in angiogenesis and tumorigenesis
Q45318299PTEN Regulation
Q39644716PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
Q34824223PTEN hamartoma tumor syndromes.
Q42412809PTEN in liver diseases and cancer
Q35056451PTEN is a negative regulator of NK cell cytolytic function.
Q50299118PTEN mRNA translation is negatively regulated by microRNAs
Q82600359PTEN promoter methylation and LOH of 10q22-23 locus in PTEN expression of ovarian clear cell adenocarcinomas
Q37420213Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis
Q37346198Pharmaco(epi)genomics in ovarian cancer
Q28384799Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and PH domain and leucine-rich repeat phosphatase cross-talk (PHLPP) in cancer cells and in transforming growth factor β-activated stem cells
Q39392171Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation
Q26798324Phytochemicals modulate carcinogenic signaling pathways in breast and hormone-related cancers
Q38879511Pivotal MicroRNAs in Melanoma: A Mini-Review
Q35578546Population differences in microRNA expression and biological implications
Q37308227Potential regulatory functions of microRNAs in the ovary
Q21245724Potential role of miR-9 and miR-223 in recurrent ovarian cancer
Q54117850Potential tumor suppressing role of microRNA-545 in epithelial ovarian cancer.
Q34803840Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma
Q35232213Potentially predictive microRNAs of gastric cancer with metastasis to lymph node
Q36889793Prediction value of miR-483 and miR-214 in prognosis and multidrug resistance of esophageal squamous cell carcinoma
Q33651583Prognostic and predictive biomarkers: tools in personalized oncology
Q34086636Prognostic biomarkers in ovarian cancer
Q36642134Prognostic implications of microRNA-100 and its functional roles in human epithelial ovarian cancer
Q36077545Prognostic significance of miR-215 in colon cancer
Q39219310Promoter methylation of the SALL2 tumor suppressor gene in ovarian cancers
Q42129357Promoter region methylation and loss of protein expression of PTEN and significance in cervical cancer
Q94526169Psoralen Suppresses Cisplatin-Mediated Resistance and Induces Apoptosis of Gastric Adenocarcinoma by Disruption of the miR196a-HOXB7-HER2 Axis
Q49378677Pterostilbene increases PTEN expression through the targeted downregulation of microRNA-19a in hepatocellular carcinoma
Q34221132RAB8 enhances TMEM205-mediated cisplatin resistance
Q36034189RBMMMDA: predicting multiple types of disease-microRNA associations
Q38432883RNA-based ovarian cancer research from 'a gene to systems biomedicine' perspective.
Q35679353Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health
Q37984588Recent trends in cancer drug resistance reversal strategies using nanoparticles
Q47828965Reciprocal regulation of miR-214 and PTEN by high glucose regulates renal glomerular mesangial and proximal tubular epithelial cell hypertrophy and matrix expansion.
Q35067942Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A
Q34478004Regulation of NANOG in cancer cells
Q58754551Regulation of PTEN expression by noncoding RNAs
Q45318301Regulation of PTEN mRNA translation
Q35034340Regulation of cancer metastasis by cell-free miRNAs
Q33892003Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors
Q24623118Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition
Q34283589Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research
Q34197212Regulation of ovarian cancer progression by microRNA-187 through targeting Disabled homolog-2.
Q34089030Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis
Q91949964Relations between approved platinum drugs and non-coding RNAs in mesothelioma
Q64270008Relationship between microRNA-27a and efficacy of neoadjuvant chemotherapy in gastric cancer and its mechanism in gastric cancer cell growth and metastasis
Q41785826Relevance of Rabbit VX2 Tumor Model for Studies on Human Hepatocellular Carcinoma: A MicroRNA-Based Study
Q36460311Restoration of miR-200c to ovarian cancer reduces tumor burden and increases sensitivity to paclitaxel
Q36152814Retracted: MicroRNA-20b (miR-20b) Promotes the Proliferation, Migration, Invasion, and Tumorigenicity in Esophageal Cancer Cells via the Regulation of Phosphatase and Tensin Homologue Expression
Q35113163Retracted: MicroRNA-214 Suppresses Oncogenesis and Exerts Impact on Prognosis by Targeting PDRG1 in Bladder Cancer
Q37441874Ribonucleases as potential modalities in anticancer therapy
Q35062972Role of Dicer in female fertility
Q33703270Role of Epigenetics in Uveal Melanoma
Q24647234Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
Q37961734Role of epigenomics in ovarian and endometrial cancers
Q34230585Role of miR-148a in hepatitis B associated hepatocellular carcinoma.
Q39387335Role of miR-19b and its target mRNAs in 5-fluorouracil resistance in colon cancer cells.
Q39261923Role of miRNAs in neuronal differentiation from human embryonic stem cell-derived neural stem cells
Q92636165Role of microRNAs as Clinical Cancer Biomarkers for Ovarian Cancer: A Short Overview
Q38258014Role of microRNAs in cancers of the female reproductive tract: insights from recent clinical and experimental discovery studies
Q26770485Role of microRNAs in chemoresistance
Q39621434Role of ribosomal protein RPS2 in controlling let-7a expression in human prostate cancer
Q38346740Role of the AKT pathway in microRNA expression of human U251 glioblastoma cells
Q34599169Roles and mechanism of miR-199a and miR-125b in tumor angiogenesis
Q98771139Roles of microRNAs in Ovarian Cancer Tumorigenesis: Two Decades Later, What Have We Learned?
Q34966603Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging
Q90043990SOX2 mediates cisplatin resistance in small-cell lung cancer with downregulated expression of hsa-miR-340-5p
Q58693575STAT3 regulated promotes ovarian cancer proliferation and cisplatin resistance
Q34999442Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection
Q35036873Scleral micro-RNA signatures in adult and fetal eyes
Q89583081Screening of potential miRNA therapeutics for the prevention of multi-drug resistance in cancer cells
Q52562510Searching for new biomarkers in ovarian cancer patients: Rationale and design of a retrospective study under the Mermaid III project.
Q39353348Selection and validation of miRNAs as normalizers for profiling expression of microRNAs isolated from thyroid fine needle aspiration smears.
Q37190115Serum high expression of miR-214 and miR-135b as novel predictor for myeloma bone disease development and prognosis
Q93199665Serum microRNAs as potential new biomarkers for cisplatin resistance in gastric cancer patients
Q35070602Shielding the messenger (RNA): microRNA-based anticancer therapies
Q36768990Silibinin-Induced Apoptosis and Downregulation of MicroRNA-21 and MicroRNA-155 in MCF-7 Human Breast Cancer Cells
Q38547893Small RNAs: Their Possible Roles in Reproductive Failure
Q34425882Small players with big roles: microRNAs as targets to inhibit breast cancer progression
Q37906461Stem cell microRNAs in senescence and immortalization: novel players in cancer therapy
Q38975225Strategic targeting of the PI3K-NFκB axis in cisplatin-resistant NSCLC.
Q33780712Strengths and limitations of laboratory procedures for microRNA detection
Q36270963Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma
Q61811539Suppression of miR-21-3p enhances TRAIL-mediated apoptosis in liver cancer stem cells by suppressing the PI3K/Akt/Bad cascade via regulating PTEN
Q33862088Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer
Q36042091Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors
Q38927716TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma.
Q33927452TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214.
Q37170030Targeting cancer stem cells: emerging role of Nanog transcription factor
Q37392708Targeting miR-21-3p inhibits proliferation and invasion of ovarian cancer cells
Q34208986Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance.
Q36545132Targeting of RUNX3 by miR-130a and miR-495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells
Q36992190Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review).
Q38841574Targeting the Wnt-Regulatory Protein CTNNBIP1 by microRNA-214 Enhances the Stemness and Self-Renewal of Cancer Stem-Like Cells in Lung Adenocarcinomas
Q29615809Targeting the phosphoinositide 3-kinase pathway in cancer
Q28472826Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms
Q38975570The Diagnostic and Prognostic Potential of microRNAs in Epithelial Ovarian Carcinoma
Q26776527The PTEN tumor suppressor gene and its role in lymphoma pathogenesis
Q37506648The PTEN-AKT3 signaling cascade as a therapeutic target in melanoma
Q24657924The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo
Q36927913The Role of microRNAs in the Tumorigenesis of Ovarian Cancer
Q92280511The Roles of miRNAs in Medulloblastoma: A Systematic Review
Q49164136The Roles of microRNAs in Regulating the Expression of PD-1/PD-L1 Immune Checkpoint
Q38203092The clinical and diagnostic role of microRNAs in ovarian carcinoma
Q35541834The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak
Q34014208The cytotoxic ribonuclease onconase targets RNA interference (siRNA).
Q33579675The expression and functions of microRNAs in pancreatic adenocarcinoma and hepatocellular carcinoma
Q24606503The functional significance of microRNA-145 in prostate cancer
Q92295239The influence of long non-coding RNAs on the response to chemotherapy in ovarian cancer
Q39029645The inhibition of miR-21 promotes apoptosis and chemosensitivity in ovarian cancer
Q37385514The mammalian ovary from genesis to revelation
Q37578813The miR-106b~25 cluster promotes bypass of doxorubicin-induced senescence and increase in motility and invasion by targeting the E-cadherin transcriptional activator EP300.
Q36091102The miR-199-dynamin regulatory axis controls receptor-mediated endocytosis.
Q26799353The miR-200 Family: Versatile Players in Epithelial Ovarian Cancer
Q42371676The miR-200 family in ovarian cancer.
Q42700734The miR-486-5p plays a causative role in prostate cancer through negative regulation of multiple tumor suppressor pathways
Q36299753The miRNA-drug resistance connection: a new era of personalized medicine using noncoding RNA begins
Q38117120The microRNA regulation of stem cells
Q37703901The molecular genetic basis of ovarian cancer and its roadmap towards a better treatment
Q87123309The prognostic significance of preoperative leukocytosis in epithelial ovarian carcinoma: a retrospective cohort study
Q35933934The prognostic value of the miR-200 family in ovarian cancer: a meta-analysis.
Q64237748The role and mechanisms of action of microRNAs in cancer drug resistance
Q37270446The role of PTEN signaling perturbations in cancer and in targeted therapy
Q26851256The role of microRNA in head and neck cancer: current knowledge and perspectives
Q37801505The role of microRNA in modulating myocardial ischemia-reperfusion injury
Q38027966The role of microRNA in the response to cisplatin treatment
Q37601781The role of microRNAs in endometriosis and associated reproductive conditions
Q34253436The role of microRNAs in ovarian cancer
Q37293916The role of microRNAs in ovarian cancer initiation and progression
Q91639454The roles of curcumin in regulating the tumor immunosuppressive microenvironment
Q36008522The transcription factor GCF2 is an upstream repressor of the small GTPAse RhoA, regulating membrane protein trafficking, sensitivity to doxorubicin, and resistance to cisplatin
Q38210867Therapeutic potential of microRNA let-7: tumor suppression or impeding normal stemness.
Q37837732Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.
Q46973951Thyroid hormone inhibits growth of hepatoma cells through induction of miR-214.
Q33721556Trail resistance induces epithelial-mesenchymal transition and enhances invasiveness by suppressing PTEN via miR-221 in breast cancer
Q34648126Transcription factor-microRNA-target gene networks associated with ovarian cancer survival and recurrence
Q37685062Transformation of human ovarian surface epithelial cells by Krüppel-like factor 8.
Q37727428Triptolide inhibits the proliferation of cells from lymphocytic leukemic cell lines in association with downregulation of NF-κB activity and miR-16-1*.
Q83840777Tumor microRNA expression patterns associated with resistance to platinum based chemotherapy and survival in ovarian cancer patients
Q24652478Twist-1 regulates the miR-199a/214 cluster during development
Q37618382Upregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression
Q49263988Upregulation of miR-146a increases cisplatin sensitivity of the non-small cell lung cancer A549 cell line by targeting JNK-2.
Q28539122Upregulation of miR-21 in cisplatin resistant ovarian cancer via JNK-1/c-Jun pathway
Q35290367Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia
Q89144265Upregulation of microRNA-3129 suppresses epithelial ovarian cancer through CD44
Q38792755Upregulation of microRNA-375 increases the cisplatin-sensitivity of human gastric cancer cells by regulating ERBB2.
Q35215772Upregulation of the inwardly rectifying potassium channel Kir2.1 (KCNJ2) modulates multidrug resistance of small-cell lung cancer under the regulation of miR-7 and the Ras/MAPK pathway
Q38941347VEGF-mediated suppression of cell proliferation and invasion by miR-410 in osteosarcoma
Q58580750Vitamin D and its receptor polymorphisms: New possible prognostic biomarkers in leukemias
Q38272241Warburg meets non-coding RNAs: the emerging role of ncRNA in regulating the glucose metabolism of cancer cells
Q34122840Whole blood-derived miRNA profiles as potential new tools for ovarian cancer screening
Q41390518Wound fluids affect miR-21, miR-155 and miR-221 expression in breast cancer cell lines, and this effect is partially abrogated by intraoperative radiation therapy treatment
Q55450209[Advances in tumor chemo-resistance regulated by MicroRNA].
Q53242728[Screening and identification of microRNAs related to acquired gefitinib-resistance in lung adenocarcinoma cell lines].
Q50095469cis-Platinum pro-drug-attached CuFeS2 nanoplates for in vivo photothermal/photoacoustic imaging and chemotherapy/photothermal therapy of cancer.
Q47134084let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery
Q38952951miR-101 regulates expression of EZH2 and contributes to progression of and cisplatin resistance in epithelial ovarian cancer
Q37548314miR-106a represses the Rb tumor suppressor p130 to regulate cellular proliferation and differentiation in high-grade serous ovarian carcinoma.
Q39493576miR-125b confers resistance of ovarian cancer cells to cisplatin by targeting pro-apoptotic Bcl-2 antagonist killer 1.
Q34195513miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222
Q91971092miR-130a-3p inhibition protects against renal fibrosis in vitro via the TGF-β1/Smad pathway by targeting SnoN
Q39439864miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
Q34436363miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells
Q50353125miR-144 Potentially Suppresses Proliferation and Migration of Ovarian Cancer Cells by Targeting RUNX1.
Q37144041miR-144 reverses chemoresistance of hepatocellular carcinoma cell lines by targeting Nrf2-dependent antioxidant pathway
Q35013059miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors
Q39025625miR-145 sensitizes ovarian cancer cells to paclitaxel by targeting Sp1 and Cdk6.
Q46272050miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages
Q23916198miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis
Q34607960miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1
Q59795094miR-205-5p Mediated Downregulation of PTEN Contributes to Cisplatin Resistance in C13K Human Ovarian Cancer Cells
Q89511641miR-20b and miR-451a Are Involved in Gastric Carcinogenesis through the PI3K/AKT/mTOR Signaling Pathway: Data from Gastric Cancer Patients, Cell Lines and Ins-Gas Mouse Model
Q47380679miR-20b promotes cellular proliferation and migration by directly regulating phosphatase and tensin homolog in prostate cancer
Q28854274miR-21 and miR-214 are consistently modulated during renal injury in rodent models
Q46209823miR-214 and hypoxia down-regulate Necl-2/CADM1 and enhance ErbB2/ErbB3 signaling
Q27023833miR-214 as a key hub that controls cancer networks: small player, multiple functions
Q64355502miR-214 is Stretch-Sensitive in Aortic Valve and Inhibits Aortic Valve Calcification
Q50299117miR-214 microRNA binds PTEN mRNA
Q36192032miR-214 promotes osteoclastogenesis by targeting Pten/PI3k/Akt pathway
Q44424639miR-214 promotes tumorigenesis by targeting lactotransferrin in nasopharyngeal carcinoma
Q34316430miR-214 targets ATF4 to inhibit bone formation.
Q47430029miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer
Q38721645miR-214-5p Targets ROCK1 and Suppresses Proliferation and Invasion of Human Osteosarcoma Cells
Q50099869miR-214-Dependent Increase of PHLPP2 Levels Mediates the Impairment of Insulin-Stimulated Akt Activation in Mouse Aortic Endothelial Cells Exposed to Methylglyoxal.
Q36189350miR-214-mediated downregulation of RNF8 induces chromosomal instability in ovarian cancer cells
Q38319595miR-214: a potential biomarker and therapeutic for different cancers
Q21091130miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics
Q35438578miR-23b targets proline oxidase, a novel tumor suppressor protein in renal cancer
Q88190776miR-3188 Regulates Cell Proliferation, Apoptosis, and Migration in Breast Cancer by Targeting TUSC5 and Regulating the p38 MAPK Signaling Pathway
Q39342904miR-34a is downregulated in cis-diamminedichloroplatinum treated sinonasal squamous cell carcinoma patients with poor prognosis.
Q58572436miR-34a targets BCL-2 to suppress the migration and invasion of sinonasal squamous cell carcinoma
Q90205451miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells
Q92094478miR-486-3p mediates hepatocellular carcinoma sorafenib resistance by targeting FGFR4 and EGFR
Q41698288miR-494 up-regulates the PI3K/Akt pathway via targetting PTEN and attenuates hepatic ischemia/reperfusion injury in a rat model
Q39095757miR-495 enhances the sensitivity of non-small cell lung cancer cells to platinum by modulation of copper-transporting P-type adenosine triphosphatase A (ATP7A).
Q37742282miR-495 promotes the chemoresistance of SCLC through the epithelial-mesenchymal transition via Etk/BMX
Q40800119miR-7 modulates chemoresistance of small cell lung cancer by repressing MRP1/ABCC1.
Q40328958miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN).
Q37734627miR-9 functions as a tumor inhibitor of cell proliferation in epithelial ovarian cancer through targeting the SDF-1/CXCR4 pathway
Q26992374miRNA and mammalian male germ cells
Q37295492miRNA profiling along tumour progression in ovarian carcinoma
Q40466065miRNA regulation is important for DNA damage repair and recognition in malignant pleural mesothelioma.
Q37697194miRNA-200a/c as potential biomarker in epithelial ovarian cancer (EOC): evidence based on miRNA meta-signature and clinical investigations
Q39289196miRNA-214 modulates radiotherapy response of non-small cell lung cancer cells through regulation of p38MAPK, apoptosis and senescence
Q28742532miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
Q39432311miRNAs and ovarian cancer: An overview
Q38633144miRNAs and ovarian cancer: a miRiad of mechanisms to induce cisplatin drug resistance
Q38031424miRNAs as biomarkers in prostate cancer
Q38366731miRNAs as prognostic and therapeutic tools in epithelial ovarian cancer
Q38003705miRNAs in breast cancer: ready for real time?
Q33827750miRNAs in human cancer.
Q37608111miRNAs modulate the drug response of tumor cells
Q38667018microRNA and Ovarian Cancer
Q33954625microRNA and cancer
Q33780259microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma
Q38729639microRNA-137 promotes apoptosis in ovarian cancer cells via the regulation of XIAP.
Q34993968microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C.
Q41972639microRNA-214 functions as a tumor suppressor in human colon cancer via the suppression of ADP-ribosylation factor-like protein 2.
Q34049130microRNA-214-mediated UBC9 expression in glioma
Q34427403microRNA-222 targeting PTEN promotes neurite outgrowth from adult dorsal root ganglion neurons following sciatic nerve transection
Q26778918microRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment
Q37592046microRNAs in gliomas: small regulators of a big problem