MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells

scientific article published on 10 July 2010

MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells is …
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scholarly articleQ13442814

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P356DOI10.1016/J.YGYNO.2010.06.004
P698PubMed publication ID20624637

P2093author name stringZhimin Li
Jing Cai
Jing Wang
Lan Xiao
Zehua Wang
Lili Yu
Sha Hu
P2860cites workMicroRNAs and cancer: profile, profile, profileQ37039839
Inhibition of microRNA with antisense oligonucleotidesQ37044780
MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cellsQ37199087
Role of microRNA in anticancer drug resistanceQ37563160
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis.Q39898008
Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cellsQ39932777
Role of microRNAs in drug-resistant ovarian cancer cellsQ39934697
Regulation of vascular endothelial growth factor expression by homeodomain-interacting protein kinase-2.Q39958914
Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cellsQ39994304
MicroRNAs as oncogenes and tumor suppressorsQ81406722
Carcinoma of the OvaryQ95826402
Transcriptional regulation of hypoxia-inducible factor 1alpha by HIPK2 suggests a novel mechanism to restrain tumor growthQ24319862
Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cellsQ24647234
miR-122 targeting with LNA/2'-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugatesQ24647285
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?Q27860893
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2Q28210189
miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cellsQ28278471
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2Q28295844
A brain-specific microRNA regulates dendritic spine developmentQ29614753
miR-21-mediated tumor growthQ29616149
MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTENQ29616575
Randomized intergroup trial of cisplatin-paclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: three-year resultsQ33332312
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cellsQ33497932
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.Q34108288
The Role of ABC Transporters in Clinical PracticeQ34268081
Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.Q34798833
A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancerQ34985302
Multiple genetic and epigenetic interacting mechanisms contribute to clonally selection of drug-resistant tumors: current views and new therapeutic prospective.Q36297321
The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein researchQ36365560
Mechanisms of multidrug resistance: the potential role of microtubule-stabilizing agentsQ36893330
OncomiRs: the discovery and progress of microRNAs in cancersQ36951319
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
P304page(s)125-130
P577publication date2010-07-10
P1433published inGynecologic OncologyQ5625182
P1476titleMiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells
P478volume119