Role of the AKT pathway in microRNA expression of human U251 glioblastoma cells

scientific article published on March 2010

Role of the AKT pathway in microRNA expression of human U251 glioblastoma cells is …
instance of (P31):
scholarly articleQ13442814
retracted paperQ45182324

External links are
P356DOI10.3892/IJO_00000542
P698PubMed publication ID20126987

P2093author name stringYu Ren
Lei Han
Xuan Zhou
Peng Xu
Chun-Sheng Kang
Chun-Zhi Zhang
Mei Mei
Pei-Yu Pu
Guang-Xiu Wang
Zhi-Fan Jia
P2860cites workHuman MicroRNA targetsQ21563637
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulatorsQ24336898
A microRNA expression signature of human solid tumors defines cancer gene targetsQ24541455
miRBase: tools for microRNA genomicsQ24649872
Identification of a PTEN-regulated STAT3 brain tumor suppressor pathwayQ24650927
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responsesQ24670080
MATCH: A tool for searching transcription factor binding sites in DNA sequencesQ24677633
An extensive class of small RNAs in Caenorhabditis elegansQ27860626
MicroRNA gene expression deregulation in human breast cancerQ27860690
A comparison of normalization methods for high density oligonucleotide array data based on variance and biasQ27860710
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cellsQ28262214
Extensive modulation of a set of microRNAs in primary glioblastomaQ28263314
The transcriptional program in the response of human fibroblasts to serumQ28292705
A microRNA component of the p53 tumour suppressor networkQ28305330
Antisense and dominant-negative AKT2 cDNA inhibits glioma cell invasionQ28569152
TRANSFAC: transcriptional regulation, from patterns to profilesQ29547394
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancerQ29547523
The phosphatidylinositol 3-Kinase AKT pathway in human cancerQ29547860
miR-21-mediated tumor growthQ29616149
MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTENQ29616575
Global and local architecture of the mammalian microRNA-transcription factor regulatory network.Q33290828
Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of TongueQ33331288
AKT plays a central role in tumorigenesisQ33944165
MYCN regulates oncogenic MicroRNAs in neuroblastomaQ34702713
Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancerQ34736348
MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1.Q34786558
PI3K signaling and miRNA expression during the response of quiescent human fibroblasts to distinct proliferative stimuliQ35605939
Canalization of development by microRNAsQ36493258
The PI3K/Akt pathway and its downstream transcriptional factors as targets for chemopreventionQ36989947
p53 enters the microRNA worldQ36998341
Specific microRNAs modulate embryonic stem cell-derived neurogenesis.Q37020782
The guardian's little helper: microRNAs in the p53 tumor suppressor networkQ37023130
MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).Q38303663
Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancerQ38314320
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomasQ40073679
Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancerQ40134000
Nonisotopic detection of microRNA using digoxigenin labeled RNA probesQ40376481
Induction of NF-kappaB by the Akt/PKB kinaseQ40950127
Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.Q42830960
Suppression of EGFR expression by antisense or small interference RNA inhibits U251 glioma cell growth in vitro and in vivoQ45855175
Molecular determinants of Akt-induced keratinocyte transformationQ46772716
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.Q52582850
The MicroRNA let-7a modulates interleukin-6-dependent STAT-3 survival signaling in malignant human cholangiocytes.Q53577688
The effects of antisense AKT2 RNA on the inhibition of malignant glioma cell growth in vitro and in vivo.Q55470672
P433issue3
P921main subjectglioblastomaQ282142
microRNA expressionQ60681249
P304page(s)665-672
P577publication date2010-03-01
P1433published inInternational Journal of OncologyQ6051527
P1476titleRole of the AKT pathway in microRNA expression of human U251 glioblastoma cells
P478volume36

Reverse relations

cites work (P2860)
Q39167421Alteration of the microRNA expression profile in human osteosarcoma cells transfected with APE1 siRNA.
Q92879081Emerging role of PI3K/AKT in tumor-related epigenetic regulation
Q55084777Glioblastoma multiforme stem cells.
Q39221558MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells.
Q47217569MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway.
Q38497875MicroRNAs and cell cycle of malignant glioma
Q39698047Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3.
Q40182494miR-506 inhibits the proliferation and invasion by targeting IGF2BP1 in glioblastoma

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