Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms

scientific article published on September 2011

Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.327
P932PMC publication ID3248223
P698PubMed publication ID21941025
P5875ResearchGate publication ID51664523

P50authorQiZhi ZhengQ58453252
Tsuyoshi IwataQ93041453
Srinivasan YegnasubramanianQ95939090
Carlise BethelQ117270276
Angelo M De MarzoQ56417148
P2093author name stringCheryl M Koh
P2860cites workETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancerQ21091136
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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cellsQ24672969
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Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical featuresQ79393350
Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcomaQ28304953
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitionsQ29614512
The polycomb group protein EZH2 is involved in progression of prostate cancerQ29614514
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Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancerQ34803786
Alterations in nucleolar structure and gene expression programs in prostatic neoplasia are driven by the MYC oncogeneQ34805348
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Polycomb group protein enhancer of zeste 2 is an oncogene that promotes the neoplastic transformation of a benign prostatic epithelial cell lineQ37478998
Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2.Q38259629
Widespread deregulation of microRNA expression in human prostate cancer.Q38297946
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.Q38304702
MicroRNA target prediction by expression analysis of host genesQ38511523
MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1betaQ39703169
A polycomb repression signature in metastatic prostate cancer predicts cancer outcomeQ40050697
MicroRNA expression profiling in prostate cancerQ40110318
The gene for polycomb group protein enhancer of zeste homolog 2 (EZH2) is amplified in late-stage prostate cancerQ40297700
Context-dependent hormone-refractory progression revealed through characterization of a novel murine prostate cancer cell line.Q40339620
ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratificationQ41489983
Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growthQ43262197
EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breastQ44864337
Myc-driven murine prostate cancer shares molecular features with human prostate tumorsQ45049671
Activated p53 suppresses the histone methyltransferase EZH2 geneQ47314793
Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.Q53332426
Specific miRNA signatures are associated with metastasis and poor prognosis in clear cell renal cell carcinoma.Q54392904
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectoverexpressionQ61643320
P304page(s)669-683
P577publication date2011-09-01
P1433published inOncotargetQ1573155
P1476titleMyc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms
P478volume2