Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2.

scientific article

Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/1947601911416357
P932PMC publication ID3161419
P698PubMed publication ID21901171
P5875ResearchGate publication ID51627059

P50authorAlessandro FaticaQ32414712
Monica MessinaQ52643450
Francesco FaziQ59548158
Sabina ChiarettiQ88418165
P2093author name stringAnna Guarini
Irene Bozzoni
Ilaria Iosue
Fabrizio Padula
Beatrice Salvatori
Nkerorema Djodji Damas
Arianna Mangiavacchi
P2860cites workRole of the polycomb repressive complex 2 in acute promyelocytic leukemiaQ24309258
Widespread microRNA repression by Myc contributes to tumorigenesisQ24647067
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer modelQ24655262
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivoQ24657924
The proto-oncogene c-myc in hematopoietic development and leukemogenesisQ28200929
MYC stimulates EZH2 expression by repression of its negative regulator miR-26aQ28291303
MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2Q28302211
Cross talk between microRNA and epigenetic regulation in adult neurogenesisQ33788417
c-Myc is a critical target for c/EBPalpha in granulopoiesis.Q33968356
EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancerQ34268216
Leukaemogenesis: more than mutant genesQ34275371
The roles of FLT3 in hematopoiesis and leukemiaQ34784925
Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cellsQ34994576
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.Q35561038
Induction of differentiation in HL60 cells by the reduction of extrachromosomally amplified c-mycQ35590462
The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.Q35804605
Transcriptional regulation and transformation by Myc proteinsQ36215755
Cooperating gene mutations in acute myeloid leukemia: a review of the literature.Q37089717
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancerQ37198891
Myc's broad reachQ37299032
Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cellsQ37385808
Role of microRNAs in hematological malignanciesQ37810078
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.Q38343552
All-trans retinoic acid induces Thrombospondin-1 expression in acute promyelocytic leukemia cells though down-regulation of its transcription repressor, c-MYC oncoproteinQ39867859
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.Q39877545
A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemiaQ40219227
c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations.Q40406189
A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells.Q43609668
Localization of amplified MYC gene sequences to double minute chromosomes in acute myelogenous leukemiaQ47564321
Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemiaQ80209025
Role of Myc in differentiation and apoptosis in HL60 cells after exposure to arsenic trioxide or all-trans retinoic acidQ80812923
P433issue5
P921main subjectleukemiaQ29496
acute myeloid leukemiaQ264118
P304page(s)585-592
P577publication date2011-05-01
P1433published inGenes & CancerQ26842471
P1476titleCritical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2
P478volume2

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cites work (P2860)
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