Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex.

scientific article

Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M114.566448
P932PMC publication ID4140267
P698PubMed publication ID24828497

P50authorYasuyuki OhkawaQ39025369
Atsushi YokoyamaQ79755703
P2093author name stringJun Kanno
Katsuhide Igarashi
Ken-Ichirou Morohashi
Akira Sugawara
Tetsuya Sato
Takashi Baba
Ryo Ito
Kiyoshi Takagi
Yurina Shishido
Maky Otsuka I
P2860cites workLigand-dependent transcription activation by nuclear receptors requires the DRIP complexQ22009519
Regulation of chromatin structure by site-specific histone H3 methyltransferasesQ24290115
Novel member of the zinc finger superfamily: A C2-HC finger that recognizes a glia-specific geneQ24304923
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancerQ24308737
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcriptionQ24312958
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1Q24336747
Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancersQ24605342
Direct conversion of fibroblasts to functional neurons by defined factorsQ24641912
Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamineQ27645835
Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous systemQ27659896
Chromatin modifications and their functionQ27861067
Coordinated histone modifications mediated by a CtBP co-repressor complexQ28191656
Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3Q28214048
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylationQ28265681
Regulation of LSD1 histone demethylase activity by its associated factorsQ28270391
Opposing LSD1 complexes function in developmental gene activation and repression programmesQ28295495
Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous systemQ28506882
Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouseQ28507900
Identification of genes that restrict astrocyte differentiation of midgestational neural precursor cellsQ28508428
Switching of the core transcription machinery during myogenesisQ28510568
Isolation and characterization of a novel member of the neural zinc finger factor/myelin transcription factor family with transcriptional repression activityQ28573701
Distribution of lysine-specific demethylase 1 in the brain of rat and its response in transient global cerebral ischemiaQ28574354
A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary glandQ28581048
An essential switch in subunit composition of a chromatin remodeling complex during neural developmentQ28585238
Histone demethylase LSD1 regulates neural stem cell proliferationQ28589881
Myt1 family recruits histone deacetylase to regulate neural transcriptionQ28592882
The diverse functions of histone lysine methylationQ29614523
Cooperation between complexes that regulate chromatin structure and transcriptionQ29614769
Plat-E: an efficient and stable system for transient packaging of retrovirusesQ29614830
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogenQ29616224
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional responseQ29616508
ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulationQ29618299
Transcription regulation and animal diversityQ29618752
Histones: annotating chromatinQ29619913
ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.Q30032679
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer modelQ32069431
"Per cell" normalization method for mRNA measurement by quantitative PCR and microarraysQ33237951
Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medicationsQ33997049
Molecular cloning and characterization of the human NIMA-related protein kinase 3 gene (NEK3).Q34133229
Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes.Q34607379
Chromatin remodelling during developmentQ34698385
The logic of chromatin architecture and remodelling at promotersQ35001999
PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.Q35661819
Regulatory diversity among metazoan co-activator complexesQ35762480
Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptorsQ36014589
Transcriptional regulation and the role of diverse coactivators in animal cellsQ36024274
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemiaQ36515569
Histone demethylation and androgen-dependent transcriptionQ36571080
Function of PTEN during the formation and maintenance of neuronal circuits in the brainQ37030409
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotencyQ37125184
Mechanisms involved in the regulation of histone lysine demethylasesQ37149074
Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cellsQ37610451
Shifting players and paradigms in cell-specific transcriptionQ37671910
Developmental regulation of transcription initiation: more than just changing the actorsQ37769668
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulationQ37799722
Nuclear receptor coregulators merge transcriptional coregulation with epigenetic regulation.Q37840446
Regulated histone methyltransferase and demethylase complexes in the control of genes by nuclear receptors.Q37926288
Transrepressive function of TLX requires the histone demethylase LSD1.Q39024215
A GluR1-cGKII interaction regulates AMPA receptor traffickingQ40046571
Low molecular weight protein-tyrosine phosphatase is involved in growth inhibition during cell differentiationQ40775530
PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.Q40911230
Low molecular weight phosphotyrosine protein phosphatase from PC12 cells. Purification, some properties and expression during neurogenesis in vitro and in vivoQ42442721
KIAA1718 is a histone demethylase that erases repressive histone methyl marks.Q42970639
Transcription strategies in terminally differentiated cells: shaken to the core.Q46029944
Toward Ligand Identification within a CCHHC Zinc-Binding Domain from the NZF/MyT1 FamilyQ58375235
P433issue26
P407language of work or nameEnglishQ1860
P304page(s)18152-18162
P577publication date2014-05-14
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex
P478volume289

Reverse relations

cites work (P2860)
Q47159917Biochemical Analysis of Histone Succinylation.
Q27335160Cellular defense against latent colonization foiled by human cytomegalovirus UL138 protein
Q47907953Chromatin remodeling and epigenetic regulation of oligodendrocyte myelination and myelin repair
Q57250768Coordinating neuronal differentiation with repression of the progenitor program: Role of the transcription factor MyT1
Q102058649Dedifferentiation and neuronal repression define familial Alzheimer's disease
Q55109898Endogenous Purification of NR4A2 (Nurr1) Identified Poly(ADP-Ribose) Polymerase 1 as a Prime Coregulator in Human Adrenocortical H295R Cells.
Q111441832Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease
Q36875240Generation and gene expression profiling of 48 transcription-factor-inducible mouse embryonic stem cell lines
Q41683480Hydroxylation of methylated DNA by TET1 in chondrocyte differentiation of C3H10T1/2 cells
Q92618477Isatin inhibits SH-SY5Y neuroblastoma cell invasion and metastasis through PTEN signaling
Q35094931LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition
Q91595536MYT1 attenuates neuroblastoma cell differentiation by interacting with the LSD1/CoREST complex
Q28081607Molecular mechanisms of acrolein-mediated myelin destruction in CNS trauma and disease
Q50501741Mutations in MYT1, encoding the myelin transcription factor 1, are a rare cause of OAVS.
Q41481489MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis.
Q57479673Myt1 and Myt1l transcription factors limit proliferation in GBM cells by repressing YAP1 expression
Q60911983Partial proteasomal degradation of Lola triggers the male-to-female switch of a dimorphic courtship circuit
Q26768602Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting
Q35133855Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes

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