| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1050226578 |
| P356 | DOI | 10.1038/SJ.ONC.1203151 |
| P698 | PubMed publication ID | 10602505 |
| P5875 | ResearchGate publication ID | 12697974 |
| P50 | author | Jesus M. Paramio | Q43100805 |
| Manuel Navarro | Q47159759 | ||
| Elena Gómez-Casero Esteban | Q73283414 | ||
| P2093 | author name string | J L Jorcano | |
| C Segrelles | |||
| P2860 | cites work | Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability | Q42829486 |
| High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
| Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F | Q73925270 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| The retinoblastoma protein and cell cycle control | Q27860722 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein | Q28260016 | ||
| Differential expression and functionally co-operative roles for the retinoblastoma family of proteins in epidermal differentiation | Q28283261 | ||
| Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A | Q28289708 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
| Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
| Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta | Q28582003 | ||
| An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1 | Q29614256 | ||
| Regulation of retinoblastoma protein functions by ectopic expression of human cyclins | Q29618320 | ||
| Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction | Q29618388 | ||
| Rho Family GTPases Bind to Phosphoinositide Kinases | Q33292549 | ||
| PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells | Q33586807 | ||
| The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway | Q33599964 | ||
| 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro | Q34452063 | ||
| The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors | Q35769059 | ||
| DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1 | Q36234063 | ||
| Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways | Q36256326 | ||
| Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases | Q36646526 | ||
| Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
| The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines | Q37537138 | ||
| Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways | Q38354870 | ||
| Modulation of cell proliferation by cytokeratins K10 and K16 | Q39445342 | ||
| Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation | Q39576120 | ||
| Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts | Q39610954 | ||
| Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase | Q40020874 | ||
| p53 and Rb: their cellular roles | Q40606655 | ||
| Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. | Q41075804 | ||
| The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1. | Q42812980 | ||
| Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. | Q42824933 | ||
| Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1. | Q42827718 | ||
| P433 | issue | 52 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | retinoblastoma | Q500695 |
| P304 | page(s) | 7462-7468 | |
| P577 | publication date | 1999-12-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein | |
| P478 | volume | 18 |
| Q35128009 | 3-Methylcholanthrene, an AhR agonist, caused cell-cycle arrest by histone deacetylation through a RhoA-dependent recruitment of HDAC1 and pRb2 to E2F1 complex |
| Q34649053 | A Dictyostelium secreted factor requires a PTEN-like phosphatase to slow proliferation and induce chemorepulsion |
| Q36386230 | A novel tumor suppressor network in squamous malignancies |
| Q24310760 | Activation of p53 by MEG3 non-coding RNA |
| Q35232272 | Autophagy regulation in cancer development and therapy |
| Q49923280 | C33-A cells transfected with E6*I or E6*II the short forms of HPV-16 E6, displayed opposite effects on cisplatin-induced apoptosis. |
| Q74688995 | CCND1- and ERBB2-gene deregulation and PTEN mutation analyses in invasive lobular carcinoma of the breast |
| Q30440601 | Cdc6 and cyclin E2 are PTEN-regulated genes associated with human prostate cancer metastasis |
| Q39365401 | Cell Cycle Control by PTEN. |
| Q40615729 | Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop. |
| Q39658846 | ESM-1 silencing decreased cell survival, migration, and invasion and modulated cell cycle progression in hepatocellular carcinoma |
| Q34583094 | Effects and mechanisms of silibinin on human hepatoma cell lines |
| Q35842249 | Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas |
| Q40757135 | Functional roles of Akt signaling in mouse skin tumorigenesis. |
| Q38142173 | Genomic Rearrangements of PTEN in Prostate Cancer |
| Q93079092 | Highlights in Resistance Mechanism Pathways for Combination Therapy |
| Q43977582 | Hypoosmotic stress stimulates growth in HepG2 cells via protein kinase B-dependent activation of activator protein-1. |
| Q37704701 | Identification and modulation of a caveolae-dependent signal pathway that regulates plasminogen activator inhibitor-1 in insulin-resistant adipocytes |
| Q34073864 | Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex. |
| Q24548285 | Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest |
| Q34047231 | Integrin-linked kinase (ILK): a "hot" therapeutic target |
| Q42628891 | Interaction effect of PTEN and CDKN1B chromosomal regions on prostate cancer linkage |
| Q27851755 | Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era. |
| Q34283477 | Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas. |
| Q46772716 | Molecular determinants of Akt-induced keratinocyte transformation |
| Q34533889 | Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10) |
| Q38384489 | Next-generation sequencing technology in prostate cancer diagnosis, prognosis, and personalized treatment |
| Q28587617 | Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1 |
| Q58134027 | Over-expression of PTEN on proliferation and apoptosis in canine mammary tumors cells |
| Q34180652 | PTEN and myotubularin phosphoinositide phosphatases: bringing bioinformatics to the lab bench |
| Q35661819 | PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. |
| Q34796595 | PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium |
| Q54674580 | PTEN promoter methylation and protein expression in normal early placentas and hydatidiform moles. |
| Q37270432 | PTEN: a new guardian of the genome. |
| Q38871799 | Palbociclib has antitumour effects on Pten-deficient endometrial neoplasias. |
| Q37431908 | Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression |
| Q34135631 | Phosphatidylinositol 3-kinases in tumor progression |
| Q24613810 | Protean PTEN: form and function |
| Q34707865 | Pten signaling in gliomas |
| Q27933247 | Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast |
| Q43825785 | Regulation of the differentiation-related gene Drg-1 during mouse skin carcinogenesis |
| Q36727409 | Retinoblastoma and phosphate and tensin homolog tumor suppressors: impact on ductal carcinoma in situ progression |
| Q38175052 | Skin Tumors Rb(eing) Uncovered. |
| Q34825957 | The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network |
| Q34229795 | The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models |
| Q35970384 | The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in Drosophila |
| Q36002446 | The elements of human cyclin D1 promoter and regulation involved |
| Q42518511 | The expression of keratin k10 in the basal layer of the epidermis inhibits cell proliferation and prevents skin tumorigenesis |
| Q33849727 | The multiple roles of PTEN in tumor suppression |
| Q37454384 | The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications. |
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