| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M308383200 |
| P698 | PubMed publication ID | 14623898 |
| P50 | author | Jean-Noël Freund | Q54290244 |
| B Mark Evers | Q89810329 | ||
| P2093 | author name string | Sunghoon Kim | |
| Dai H Chung | |||
| Junghee Kang | |||
| Claire Domon-Dell | |||
| P2860 | cites work | Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. | Q41128352 |
| Tumor necrosis factor promotes phosphorylation and binding of insulin receptor substrate 1 to phosphatidylinositol 3-kinase in 3T3-L1 adipocytes | Q41239746 | ||
| NF-kappa B-like factors mediate interleukin 1 induction of c-myc gene transcription in fibroblasts | Q41604208 | ||
| Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation | Q42795799 | ||
| The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms | Q42808605 | ||
| Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN. | Q43621579 | ||
| Possible new role for NF-kappaB in the resolution of inflammation. | Q43811439 | ||
| PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway | Q44165168 | ||
| Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis | Q44246409 | ||
| Activation of PPARgamma increases PTEN expression in pancreatic cancer cells | Q44283207 | ||
| Germline mutations in PTEN are present in Bannayan-Zonana syndrome | Q48046915 | ||
| TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways | Q24317441 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation | Q24318742 | ||
| NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176 | Q24319941 | ||
| Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN | Q24322051 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex | Q24329065 | ||
| Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity | Q27860643 | ||
| Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B | Q27860731 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase | Q28144326 | ||
| NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling | Q28144330 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
| PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway | Q28588309 | ||
| TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40 | Q28610812 | ||
| Regulation of PTEN transcription by p53 | Q28646911 | ||
| Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation | Q28776205 | ||
| TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB | Q29614706 | ||
| Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
| New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway | Q29616144 | ||
| The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation | Q29617813 | ||
| Suppression of TNF-alpha-induced apoptosis by NF-kappaB | Q29618717 | ||
| Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death | Q29620021 | ||
| Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence | Q36707669 | ||
| Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain | Q36818855 | ||
| Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kappaB and Myc/Max | Q38324216 | ||
| NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition | Q39445143 | ||
| The significance of DNA and protein adducts in human biomonitoring studies | Q39640488 | ||
| Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha | Q40401245 | ||
| Induced stabilization of IκBα can facilitate its re‐synthesis and prevent sequential degradation | Q40653906 | ||
| PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein. | Q40911230 | ||
| Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras. | Q41074033 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| P1104 | number of pages | 7 | |
| P304 | page(s) | 4285-4291 | |
| P577 | publication date | 2003-11-17 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop | |
| P478 | volume | 279 |
| Q36372711 | A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection |
| Q24650473 | APE1/Ref-1 regulates PTEN expression mediated by Egr-1 |
| Q35921220 | Activation of IKK/NF-κB provokes renal inflammatory responses in guanylyl cyclase/natriuretic peptide receptor-A gene-knockout mice |
| Q35320386 | Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway |
| Q34240789 | Beta catenin and cytokine pathway dysregulation in patients with manifestations of the "PTEN hamartoma tumor syndrome" |
| Q33610075 | Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis |
| Q80265621 | Bilirubin-induced cell toxicity involves PTEN activation through an APE1/Ref-1-dependent pathway |
| Q39273477 | Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals |
| Q41838103 | Carbon monoxide donors or heme oxygenase-1 (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death |
| Q36313163 | Class reunion: PTEN joins the nuclear crew. |
| Q21285160 | Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process |
| Q34733201 | Down-regulation of PTEN by HCV core protein through activating nuclear factor-κB. |
| Q37281508 | Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo. |
| Q38702353 | Effect of Helix aspersa extract on TNFα, NF-κB and some tumor suppressor genes in breast cancer cell line Hs578T. |
| Q38518025 | Effect of lipopolysaccharide on global gene expression in the immature rat brain |
| Q39125279 | Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway |
| Q58115517 | Enhanced mRNA FISH with compact quantum dots |
| Q39985969 | Focal adhesion kinase mediates the interferon-gamma-inducible GTPase-induced phosphatidylinositol 3-kinase/Akt survival pathway and further initiates a positive feedback loop of NF-kappaB activation |
| Q34107159 | Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production |
| Q40605490 | HIV-1 Vpr Inhibits Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Inducing MicroRNA miR-942-5p and Activating NF-κB Signaling |
| Q37559230 | Hepatic MiR-291b-3p Mediated Glucose Metabolism by Directly Targeting p65 to Upregulate PTEN Expression |
| Q34162920 | Herpes simplex virus type 2 triggers reactivation of Kaposi's sarcoma-associated herpesvirus from latency and collaborates with HIV-1 Tat. |
| Q33276186 | Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression |
| Q98467261 | Inflammatory Mediators in Glioma Microenvironment Play a Dual Role in Gliomagenesis and Mesenchymal Stem Cell Homing: Implication for Cellular Therapy |
| Q45072273 | LPS Induced Acute Lung Injury Involves the NF-κB-mediated Downregulation of SOX18. |
| Q36055547 | Lipocalin 2: novel component of proinflammatory signaling in Alzheimer's disease |
| Q39115959 | Matrine activates PTEN to induce growth inhibition and apoptosis in V600EBRAF harboring melanoma cells |
| Q36228081 | MiRNA-891a-5p mediates HIV-1 Tat and KSHV Orf-K1 synergistic induction of angiogenesis by activating NF-κB signaling |
| Q33577518 | MicroRNA regulation of innate immune responses in epithelial cells |
| Q30972954 | NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses |
| Q37615954 | NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction |
| Q36985073 | NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation. |
| Q34542040 | Nuclear factor of activated T cells (NFAT) signaling regulates PTEN expression and intestinal cell differentiation |
| Q28387039 | Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells |
| Q34166917 | Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway |
| Q36337966 | Oncogenic PI3K deregulates transcription and translation |
| Q46402658 | PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation |
| Q35748448 | PKCdelta-mediated regulation of FLIP expression in human colon cancer cells |
| Q39994850 | PPARbeta/delta agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF-kappaB signals |
| Q42412809 | PTEN in liver diseases and cancer |
| Q34100984 | PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells. |
| Q30425294 | Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1. |
| Q38980308 | Pro-angiogenic effects of MDM2 through HIF-1α and NF-κB mediated mechanisms in LNCaP prostate cancer cells |
| Q46709248 | RNA sequencing supports distinct reactive oxygen species-mediated pathways of apoptosis by high and low size mass fractions of Bay leaf (Lauris nobilis) in HT-29 cells |
| Q37113710 | Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition |
| Q33556577 | SMAD4 loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells |
| Q38969138 | Sequestosome 1/p62 facilitates HER2-induced mammary tumorigenesis through multiple signaling pathways |
| Q33678607 | Simvastatin induces derepression of PTEN expression via NFkappaB to inhibit breast cancer cell growth |
| Q83381970 | Stromal miR-320 keeps an oncogenic secretome in check |
| Q37175517 | TGF-beta downregulates PTEN via activation of NF-kappaB in pancreatic cancer cells |
| Q40013396 | TNF-alpha impairs the S-G2/M cell cycle checkpoint and cyclobutane pyrimidine dimer repair in premalignant skin cells: role of the PI3K-Akt pathway |
| Q34828662 | The PTEN-PI3K pathway: of feedbacks and cross-talks |
| Q53697003 | The TNF-α-induced expression of miR-130b protects cervical cancer cells from the cytotoxicity of TNF-α. |
| Q38631619 | The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells |
| Q39337955 | Towards Targeting PI3K-Dependent Regulation of Gene Expression in Brain Cancer |
| Q34173719 | Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors |
| Q64970166 | USP13 functions as a tumor suppressor by blocking the NF-kB-mediated PTEN downregulation in human bladder cancer. |
| Q39906678 | Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes |
| Q39218984 | Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency |
| Q24296637 | Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation |
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