scholarly article | Q13442814 |
P356 | DOI | 10.1523/JNEUROSCI.1002-07.2007 |
P8608 | Fatcat ID | release_psk3lluvofhrln3oupxu42766e |
P932 | PMC publication ID | 6672188 |
P698 | PubMed publication ID | 17699657 |
P5875 | ResearchGate publication ID | 6139389 |
P50 | author | Ignacio Torres Aleman | Q43179267 |
P2093 | author name string | Ana M Fernandez | |
Miguel Garcia-Garcia | |||
Paloma Carrero | |||
Silvia Fernandez | |||
P2860 | cites work | Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription | Q24292438 |
Human CD14 mediates recognition and phagocytosis of apoptotic cells | Q24336506 | ||
DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways | Q28138804 | ||
Transcription factors of the NFAT family: regulation and function | Q28237645 | ||
Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages | Q28283333 | ||
Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes | Q28345343 | ||
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis | Q28505151 | ||
Developmental regulation of the mouse IGF-I exon 1 promoter region by calcineurin activation of NFAT in skeletal muscle | Q28508516 | ||
Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis | Q28592161 | ||
Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus. | Q32062012 | ||
Association of calcineurin with mitochondrial proteins | Q33241148 | ||
Reactive microgliosis | Q33604483 | ||
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models | Q33947378 | ||
Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma | Q34249625 | ||
Serum growth factors and neuroprotective surveillance: focus on IGF-1. | Q34265977 | ||
Glia and their cytokines in progression of neurodegeneration | Q34382722 | ||
Phosphatases: counterregulatory role in inflammatory cell signaling | Q34487892 | ||
Inflammation in neurodegenerative disease--a double-edged sword | Q34775762 | ||
Neuro-inflammation as a therapeutic target in amyotrophic lateral sclerosis. | Q35045218 | ||
The impact of systemic infection on the progression of neurodegenerative disease. | Q35058498 | ||
Astrocyte apoptosis: implications for neuroprotection | Q35737824 | ||
Molecular mechanisms of neuroprotective action of immunosuppressants--facts and hypotheses. | Q35748218 | ||
Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia | Q35802448 | ||
Role of inflammation in neurodegenerative diseases | Q36125754 | ||
Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkappaB/Rel activation through calcineurin-mediated inactivation of IkappaBbeta | Q36323494 | ||
Astrocyte dysfunction in neurological disorders: a molecular perspective | Q36404127 | ||
Insulin-like growth factor I is required for vessel remodeling in the adult brain | Q36449180 | ||
Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop. | Q40615729 | ||
Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein | Q41216893 | ||
FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin | Q41618754 | ||
Reactive astrocytes: cellular and molecular cues to biological function | Q41673434 | ||
Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis. | Q43794664 | ||
NFAT4 is expressed in primary astrocytes and activated by glutamate | Q44387885 | ||
Transcriptional regulation of IGF-I expression in skeletal muscle | Q44963948 | ||
Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice | Q46254778 | ||
'PPAR'ting ways with inflammation. | Q46715539 | ||
Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration. | Q46890625 | ||
Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1. | Q46895776 | ||
The LPS receptor (CD14) links innate immunity with Alzheimer's disease | Q47405789 | ||
Co-ordinated and cellular specific induction of the components of the IGF/IGFBP axis in the rat brain following hypoxic-ischemic injury | Q48399935 | ||
Generation of constitutively active calcineurin by calpain contributes to delayed neuronal death following mouse brain ischemia | Q48485570 | ||
Insulin-like growth factor I modulates c-Fos induction and astrocytosis in response to neurotoxic insult | Q48825477 | ||
Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide. | Q48901120 | ||
Reduction of calcineurin enzymatic activity in Alzheimer's disease: correlation with neuropathologic changes | Q48958065 | ||
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes | Q50111962 | ||
beta-amyloid peptides are cytotoxic to astrocytes in culture: a role for oxidative stress. | Q53342702 | ||
Free insulin-like growth factor (IGF)-I and IGF binding proteins 2, 5, and 6 in spinal motor neurons in amyotrophic lateral sclerosis | Q73179770 | ||
Insulin-like growth factor-I stimulates dephosphorylation of ikappa B through the serine phosphatase calcineurin (protein phosphatase 2B) | Q74270283 | ||
Expression of tumor necrosis factor alpha (TNFalpha) following transient cerebral ischemia | Q75372373 | ||
TNF-alpha-induced tolerance to ischemic injury involves differential control of NF-kappaB transactivation: the role of NF-kappaB association with p300 adaptor | Q77584948 | ||
Distinctive calcineurin-dependent (FK506-sensitive) mechanisms regulate the production of the CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES vs IL-2 and TNF-alpha by activated human T cells | Q77759726 | ||
Blockade of NFAT activation by the second calcineurin binding site | Q82238797 | ||
A global analysis of cross-talk in a mammalian cellular signalling network | Q83339233 | ||
P433 | issue | 33 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | inflammation | Q101991 |
astrocyte | Q502961 | ||
P304 | page(s) | 8745-8756 | |
P577 | publication date | 2007-08-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals | |
P478 | volume | 27 |
Q39093102 | A phosphatase-independent gain-of-function mutation in PTEN triggers aberrant cell growth in astrocytes through an autocrine IGF-1 loop. |
Q93205779 | Astrocytes: Heterogeneous and Dynamic Phenotypes in Neurodegeneration and Innate Immunity |
Q48176684 | Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice |
Q35846785 | Astroglial NF-κB mediates oxidative stress by regulation of NADPH oxidase in a model of retinal ischemia reperfusion injury. |
Q47547973 | Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes |
Q92006668 | Axonal Protection by Tacrolimus with Inhibition of NFATc1 in TNF-Induced Optic Nerve Degeneration |
Q36534321 | Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury. |
Q38881070 | Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-β-Induced Neuronal Death. |
Q90429677 | Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases |
Q49189820 | Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice |
Q90632253 | Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and Degradation |
Q34234080 | Calcineurin and glial signaling: neuroinflammation and beyond |
Q47844226 | Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: control on nuclear factor-κB signaling in consolidation and reconsolidation |
Q40741759 | Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function |
Q39128188 | Calcineurin regulates nuclear factor I dephosphorylation and activity in malignant glioma cell lines |
Q39661848 | Calcineurin β protects brain after injury by activating the unfolded protein response |
Q40179990 | Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice |
Q38113356 | Calcium dysregulation and neuroinflammation: discrete and integrated mechanisms for age-related synaptic dysfunction |
Q40009971 | Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes. |
Q37434914 | Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. |
Q59049611 | Cytokine Serum Levels as Potential Biological Markers for the Psychopathology in Schizophrenia |
Q50546416 | Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin. |
Q39495638 | Differential effect of traumatic brain injury on the nuclear factor of activated T Cells C3 and C4 isoforms in the rat hippocampus |
Q33624793 | Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures |
Q26797399 | Elusive roles for reactive astrocytes in neurodegenerative diseases |
Q43866256 | Expression and activities of N-myristoyltransferase and calcineurin in normal and inflamed lungs |
Q36541898 | Frataxin deficiency unveils cell-context dependent actions of insulin-like growth factor I on neurons |
Q38094638 | Generating new neurons to circumvent your fears: the role of IGF signaling. |
Q28577238 | Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats |
Q36808464 | Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity. |
Q64969921 | Intracellular Ca2+ Increases and Connexin 43 Hemichannel Opening Are Necessary but Not Sufficient for Thy-1-Induced Astrocyte Migration. |
Q54688691 | Involvement of SRC-suppressed C kinase substrate in neuronal death caused by the lipopolysaccharide-induced reactive astrogliosis. |
Q46620286 | Mechanical lesion activates newly identified NFATc1 in primary astrocytes: implication of ATP and purinergic receptors. |
Q35682349 | Mechanisms of dendritic spine remodeling in a rat model of traumatic brain injury |
Q36654889 | Modulation of inflammatory cytokines and mitogen-activated protein kinases by acetate in primary astrocytes |
Q51033680 | NFATc3 promotes Ca(2+) -dependent MMP3 expression in astroglial cells. |
Q40060551 | NFATs and Alzheimer's Disease. |
Q42735129 | Protein phosphatase 2B (PP2B, calcineurin) in Paramecium: partial characterization reveals that two members of the unusually large catalytic subunit family have distinct roles in calcium-dependent processes |
Q47263918 | Psychiatric polygenic risk associates with cortical morphology and functional organization in aging |
Q38017625 | Reactive astrogliosis after spinal cord injury-beneficial and detrimental effects. |
Q48832254 | Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology. |
Q42547344 | Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injury |
Q54405372 | Response of transcription factor NFATc3 to excitotoxic and traumatic brain insults: identification of a subpopulation of reactive astrocytes. |
Q27303152 | Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease |
Q42289447 | Signaling pathways implicated in the stimulation of beta-cell proliferation by extracellular matrix |
Q37302851 | Targeted activation of astrocytes: a potential neuroprotective strategy. |
Q42352469 | Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease. |
Q37004725 | Targeting insulin-like growth factor-1 to treat Alzheimer's disease |
Q28067014 | The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases |
Q38123243 | The impact of neuroimmune changes on development of amyloid pathology; relevance to Alzheimer's disease. |
Q48601088 | The insulin-like growth factor I receptor regulates glucose transport by astrocytes. |
Q37994953 | The many faces of insulin-like peptide signalling in the brain |
Q36348658 | The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease |
Q37784863 | The roles of TNF in brain dysfunction and disease |
Q26775092 | Therapeutic Targets for Neurodevelopmental Disorders Emerging from Animal Models with Perinatal Immune Activation |
Q86512637 | Traumatic Brain Injury Causes a Tacrolimus-Sensitive Increase in Non-Convulsive Seizures in a Rat Model of Post-Traumatic Epilepsy |
Q37115203 | Ulinastatin attenuates neuropathic pain induced by L5-VRT via the calcineurin/IL-10 pathway. |
Q49884884 | Understanding Progressive Multifocal Leukoencephalopathy Risk in Multiple Sclerosis Patients Treated with Immunomodulatory Therapies: A Bird's Eye View |
Q48713451 | Variation in PPP3CC Genotype Is Associated with Long-Term Recovery after Severe Brain Injury. |