Epithelial Pten controls acute lung injury and fibrosis by regulating alveolar epithelial cell integrity. (scientific article published on 13 December 2012)

PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model

Q32069431

Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition

Q33576663

The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression

Q33784365

Epithelial repair mechanisms in the lung

Q33916933

???

Q28215495

PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration

Q34228582

The chitinase-like proteins breast regression protein-39 and YKL-40 regulate hyperoxia-induced acute lung injury.

Q34269049

The modular phosphorylation and activation of p70s6k.

Q34434557

Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10)

Q34533889

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair

Q34699422

Animal models of acute lung injury

Q34795312

Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia

Q35022890

Differential effects of claudin-3 and claudin-4 on alveolar epithelial barrier function

Q35087018

Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling.

Q35229097

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

Q35641181

Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis

Q36229334

Apoptosis and epithelial injury in the lungs

Q36284866

Activated Akt protects the lung from oxidant-induced injury and delays death of mice

Q36376143

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

Q36742285

Advances in mechanisms of repair and remodelling in acute lung injury

Q37081002

Inhibition of the phosphatase PTEN protects mice against oleic acid-induced acute lung injury

Q37230865

The role of PTEN signaling perturbations in cancer and in targeted therapy

Q37270446

The contribution of epithelial sodium channels to alveolar function in health and disease.

Q37285162

Claudin-4 augments alveolar epithelial barrier function and is induced in acute lung injury

Q37343892

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

Q37347217

Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury

Q37423117

Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis

Q37558464

Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases

Q37769281

Inducible expression of Snail selectively increases paracellular ion permeability and differentially modulates tight junction proteins

Q40414624

Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.

Q41377207

Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome

Q43616371

Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain.

Q50793273

Epithelial responses to lung injury: role of the extracellular matrix.

Q52627609

p70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells.

Q54520275

Idiopathic pulmonary fibrosis

Q56764887

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

acute lung injury

Q4677935

P304

page(s)

262-275

P577

publication date

2012-12-13

P1433

published in

American Journal of Respiratory and Critical Care Medicine

Q4744267

P1476

title

Epithelial Pten controls acute lung injury and fibrosis by regulating alveolar epithelial cell integrity

P478

volume

187

Reverse relations

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P356	DOI	10.1164/RCCM.201205-0851OC
P698	PubMed publication ID	23239155