Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair

scientific article

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.BJP.0707501
P932PMC publication ID2189995
P698PubMed publication ID17922022
P5875ResearchGate publication ID5923066

P2093author name stringJ-P Lai
J T Dalton
D L Knoell
P2860cites workEvidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2Q22253866
Phosphorylation of the PTEN tail regulates protein stability and functionQ22254305
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane associationQ27620298
The phosphoinositide 3-kinase pathwayQ27860738
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylationQ28139447
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphateQ28301966
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
Suppression of cell migration in ovarian cancer cells mediated by PTEN overexpression.Q30733464
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer modelQ32069431
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signalingQ33828931
Bisperoxovanadium compounds are potent PTEN inhibitors.Q34321332
Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxiaQ35022890
Airway remodeling in asthma: new insightsQ35067523
Mechanisms of pulmonary edema clearanceQ36281624
Protection of epithelial cells by keratinocyte growth factor signalingQ36284871
Activated Akt protects the lung from oxidant-induced injury and delays death of miceQ36376143
Physiology of fetal lung fluid clearance and the effect of laborQ36426164
PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling.Q36576538
Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary diseaseQ36634751
Use of vanadate as protein-phosphotyrosine phosphatase inhibitorQ37479498
Specific inhibition of PTEN expression reverses hyperglycemia in diabetic miceQ38290824
Positive regulation of ERK activation and MKP-1 expression by peroxovanadium complex bpV (phen).Q40462965
Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cellsQ40519298
Retinoic acids inhibit inducible nitric oxide synthase expression in mesangial cellsQ40937999
Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma.Q42815905
An in vitro model of differentiated human airway epithelia. Methods for establishing primary cultures.Q51718690
Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas.Q52180037
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors.Q53439669
Frequent inactivation of PTEN/MMAC1 in primary prostate cancerQ57240096
Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadateQ71973575
Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimeticsQ72772936
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignanciesQ73722520
Activation of MAPK by potassium bisperoxo(1,10-phenanthroline)oxovanadate (V)Q77894066
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)1172-1184
P577publication date2007-10-08
P1433published inBritish Journal of PharmacologyQ919631
P1476titlePhosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair
P478volume152

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cites work (P2860)
Q34236641A new role for PTEN in regulating transient receptor potential canonical channel 6-mediated Ca2+ entry, endothelial permeability, and angiogenesis
Q33518037A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survival
Q30389607Accelerated wound healing by mTOR activation in genetically defined mouse models.
Q37274788Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces apoptosis in nonproliferating macrophages by a phosphatase-independent mechanism
Q36162213Axonal regeneration induced by blockade of glial inhibitors coupled with activation of intrinsic neuronal growth pathways
Q39742541Characterisation of the PTEN inhibitor VO-OHpic
Q34831381Downregulation of PTEN at corneal wound sites accelerates wound healing through increased cell migration
Q42997819Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.
Q43564152Epithelial Pten controls acute lung injury and fibrosis by regulating alveolar epithelial cell integrity.
Q33916933Epithelial repair mechanisms in the lung
Q39648636Formyl Peptide Receptor Ligands Promote Wound Closure in Lung Epithelial Cells
Q42473199Harnessing the Electric Spark of Life to Cure Skin Wounds
Q37230865Inhibition of the phosphatase PTEN protects mice against oleic acid-induced acute lung injury
Q34259817Lipopolysaccharide induces lung fibroblast proliferation through Toll-like receptor 4 signaling and the phosphoinositide3-kinase-Akt pathway
Q28392910Lung inflammation, injury, and proliferative response after repetitive particulate hexavalent chromium exposure
Q28397511Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium
Q35056954Mechanism of glucose-6-phosphate dehydrogenase-mediated regulation of coronary artery contractility.
Q37411620Multifunctional Thioredoxin-Like Protein from the Gastrointestinal Parasitic Nematodes Strongyloides ratti and Trichuris suis Affects Mucosal Homeostasis.
Q24337323Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
Q91159651Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selectivity of Cancer Chemotherapeutics
Q49550289PTEN Inhibition in Human Disease Therapy
Q34228582PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration
Q41847531PTEN: a promising pharmacological target to enhance epithelial wound healing
Q38406254PTEN: a yin-yang master regulator protein in health and disease
Q53173701Periostin, a matricellular protein, accelerates cutaneous wound repair by activating dermal fibroblasts.
Q90728541Pharmacological PTEN inhibition: potential clinical applications and effects in tissue regeneration
Q39172025Phospho-tyrosine phosphatase inhibitor Bpv(Hopic) enhances C2C12 myoblast migration in vitro. Requirement of PI3K/AKT and MAPK/ERK pathways
Q30432487Phosphoinositide 3-kinase gamma required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung
Q39117557Preclinical evaluation of dipotassium bisperoxo (picolinato) oxovanadate V for the treatment of pediatric low-grade gliomas
Q34574283Propofol pretreatment attenuates lipopolysaccharide-induced acute lung injury in rats by activating the phosphoinositide-3-kinase/Akt pathway
Q37094068Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease
Q42820733Regulation of taurine homeostasis by protein kinase CK2 in mouse fibroblasts.
Q89535073Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury
Q93141753miR-20a-5p regulates pulmonary surfactant gene expression in alveolar type II cells
Q50053242mir-106a regulates cell proliferation and apoptosis of colon cancer cells through targeting the PTEN/PI3K/AKT signaling pathway

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