scholarly article | Q13442814 |
P356 | DOI | 10.1002/J.1552-4876.2013.31364.X |
P698 | PubMed publication ID | 23613428 |
P50 | author | Charis Eng | Q37385393 |
P2093 | author name string | Jessica Mester | |
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Germline mutations in PTEN are present in Bannayan-Zonana syndrome | Q48046915 | ||
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Localization of the gene for Cowden disease to chromosome 10q22–23 | Q57694734 | ||
Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model | Q22337253 | ||
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling | Q24536092 | ||
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Germline mutation of the tumour suppressor PTEN in Proteus syndrome | Q24672675 | ||
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Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis | Q28211005 | ||
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Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
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PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model | Q32069431 | ||
Cowden syndrome and Lhermitte-Duclos disease in a family: a single genetic syndrome with pleiotropy? | Q33674349 | ||
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice | Q33943166 | ||
Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53. | Q34399395 | ||
Reduction of Pten dose leads to neoplastic development in multiple organs of Pten (shRNA) mice | Q34479331 | ||
PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome | Q34504165 | ||
Cowden syndrome and Bannayan Riley Ruvalcaba syndrome represent one condition with variable expression and age-related penetrance: results of a clinical study of PTEN mutation carriers | Q34579796 | ||
Lifetime cancer risks in individuals with germline PTEN mutations. | Q35681689 | ||
P577 | publication date | 2013-04-09 | |
P1433 | published in | American Journal of Medical Genetics Part C: Seminars in Medical Genetics | Q15749239 |
P1476 | title | When Overgrowth Bumps Into Cancer: The PTEN-Opathies |
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