scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1053220766 |
P356 | DOI | 10.1038/SJ.ONC.1205054 |
P8608 | Fatcat ID | release_sie2vlhywne7bgvcfkedngxrfe |
P698 | PubMed publication ID | 11803475 |
P5875 | ResearchGate publication ID | 11556520 |
P50 | author | Young Whang | Q71283424 |
P2093 | author name string | Xiu-Juan Yuan | |
P2860 | cites work | Regulation of cell death protease caspase-9 by phosphorylation | Q28288607 |
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems | Q28586004 | ||
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane | Q28647586 | ||
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB | Q29614706 | ||
Two CD95 (APO-1/Fas) signaling pathways | Q29619631 | ||
Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs. | Q30654525 | ||
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model | Q32069431 | ||
Apoptosis control by death and decoy receptors | Q33597389 | ||
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway | Q33599964 | ||
Biochemical pathways of caspase activation during apoptosis | Q33804316 | ||
Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis | Q33875874 | ||
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes | Q33888184 | ||
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice | Q34420980 | ||
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression | Q36067596 | ||
Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. | Q39451375 | ||
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release | Q39576439 | ||
Cell cycle arrest by the PTEN tumor suppressor is target cell specific and may require protein phosphatase activity | Q40768754 | ||
A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line | Q40784934 | ||
Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells | Q40811052 | ||
Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis | Q40817486 | ||
Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis | Q40925076 | ||
Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism | Q40969097 | ||
Lipopolysaccharide mediates endothelial apoptosis by a FADD-dependent pathway | Q41020707 | ||
FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b. | Q41085784 | ||
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis | Q41224805 | ||
Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance | Q43680908 | ||
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 | ||
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors | Q24310559 | ||
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis | Q24310597 | ||
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade | Q24311006 | ||
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit | Q24554482 | ||
A simplified system for generating recombinant adenoviruses | Q24682328 | ||
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt | Q28255373 | ||
FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis | Q28265012 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 319-327 | |
P577 | publication date | 2002-01-01 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway | |
P478 | volume | 21 |
Q21245772 | An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells |
Q38350631 | Androgen and the blocking of radiation-induced sensitization to Fas-mediated apoptosis through c-jun induction in prostate cancer cells |
Q35743146 | Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks |
Q36282200 | Apoptosis evasion: the role of survival pathways in prostate cancer progression and therapeutic resistance |
Q39876998 | Apoptotic signaling induced by benzamide riboside: an in vitro study |
Q91593491 | Association between PTEN and clinical-pathological features of osteosarcoma |
Q58572361 | Association of PTEN expression with liver function and inflammatory changes in patients with liver cancer after chemotherapy |
Q89366343 | Basement membrane extract attenuates the more malignant gene expression profile accentuated by fibronectin in prostate cancer cells |
Q41460345 | CF101, an agonist to the A3 adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model |
Q37655422 | Cancer cell-oriented migration of mesenchymal stem cells engineered with an anticancer gene (PTEN): an imaging demonstration. |
Q39365401 | Cell Cycle Control by PTEN. |
Q35184335 | Clinical implications of the tumor necrosis factor family in benign and malignant hematologic disorders |
Q37832083 | Combined modality therapy with TRAIL or agonistic death receptor antibodies. |
Q44319730 | Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation |
Q36235233 | Development of Ad-mda7/IL-24-resistant lung cancer cell lines |
Q33517866 | Disruption of occludin function in polarized epithelial cells activates the extrinsic pathway of apoptosis leading to cell extrusion without loss of transepithelial resistance |
Q40333039 | Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway |
Q41439657 | Exploring prostate cancer genome reveals simultaneous losses of PTEN, FAS and PAPSS2 in patients with PSA recurrence after radical prostatectomy |
Q81228758 | Expression and significance of PTEN and VEGF in canine mammary gland tumours |
Q28204251 | FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer |
Q39994736 | FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells |
Q24300138 | Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis |
Q34194118 | Functional analysis of the protein phosphatase activity of PTEN |
Q55000578 | Functional miRNAs in breast cancer drug resistance. |
Q35648549 | Gene therapy progress and prospects: cancer gene therapy using tumour suppressor genes. |
Q50504848 | Green tea polyphenol epigallocatechin-3-gallate enhances 5-fluorouracil-induced cell growth inhibition of hepatocellular carcinoma cells. |
Q33560795 | Growth suppression of human lung cancer cells and implanted tumors by adenovirus-mediated transfer of the PTEN gene |
Q35756901 | Interferon-gamma and TRAIL in human breast tumor cells |
Q39733982 | Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells. |
Q39863924 | Mesenchymal stem cell-mediated cancer therapy: A dual-targeted strategy of personalized medicine |
Q38569206 | Mitoxantrone, More than Just Another Topoisomerase II Poison. |
Q58134027 | Over-expression of PTEN on proliferation and apoptosis in canine mammary tumors cells |
Q33236931 | Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner |
Q37099930 | PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15. |
Q35146572 | PTEN signaling pathways in melanoma |
Q49831544 | Paeoniflorin induces G2/M cell cycle arrest and caspase-dependent apoptosis through the upregulation of Bcl-2 X-associated protein and downregulation of B-cell lymphoma 2 in human osteosarcoma cells |
Q40369101 | Phorbol ester-induced apoptosis in prostate cancer cells via autocrine activation of the extrinsic apoptotic cascade: a key role for protein kinase C delta |
Q40669025 | Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3. |
Q35547017 | Prostate Development and Carcinogenesis |
Q35756915 | Regulation of sensitivity to TRAIL by the PTEN tumor suppressor. |
Q61810420 | Role of miRNA in the regulation of cannabidiol-mediated apoptosis in neuroblastoma cells |
Q33554975 | Rosiglitazone sensitizes hepatocellular carcinoma cell lines to 5-fluorouracil antitumor activity through activation of the PPARgamma signaling pathway |
Q37691830 | Targeting anoikis resistance in prostate cancer metastasis |
Q45038240 | The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing hTERT mRNA levels. |
Q28189694 | The alpha-chain of the nascent polypeptide-associated complex binds to and regulates FADD function |
Q37688267 | The application of mRNA-based gene transfer in mesenchymal stem cell-mediated cytotoxicity of glioma cells |
Q38175297 | The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells. |
Q54112403 | The impact of phosphatases on proliferative and survival signaling in cancer. |
Q35632676 | The oncogenic microRNA miR-21 promotes regulated necrosis in mice |
Q42707163 | The role of Pten/Akt signaling pathway involved in BPA-induced apoptosis of rat Sertoli cells |
Q46908073 | The targeting of phosphoinositide-3 kinase attenuates pulmonary metastatic tumor growth following laparotomy |
Q34566017 | Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells |
Q92637459 | Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma |
Q30572057 | Tumour cell survival mechanisms in lethal metastatic prostate cancer differ between bone and soft tissue metastases |
Q37156128 | Vitamin k2, a naturally occurring menaquinone, exerts therapeutic effects on both hormone-dependent and hormone-independent prostate cancer cells |
Q44415202 | c‐Jun NH2‐terminal kinase‐dependent fas activation contributes to etoposide‐induced apoptosis in p53‐mutated prostate cancer cells |
Q40404616 | p38 and EGF receptor kinase-mediated activation of the phosphatidylinositol 3-kinase/Akt pathway is required for Zn2+-induced cyclooxygenase-2 expression. |
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