| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1999PNAS...96.7088S |
| P356 | DOI | 10.1073/PNAS.96.12.7088 |
| P932 | PMC publication ID | 22065 |
| P698 | PubMed publication ID | 10359843 |
| P5875 | ResearchGate publication ID | 24452987 |
| P50 | author | Ville Wallenius | Q43851679 |
| Klara Sjögren | Q55029989 | ||
| Stanko Skrtic | Q56985705 | ||
| Claes Ohlsson | Q60502755 | ||
| P2093 | author name string | D LeRoith | |
| J L Liu | |||
| O Vidal | |||
| J O Jansson | |||
| O G Isaksson | |||
| J Törnell | |||
| K Blad | |||
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| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | preproinsulin | Q7240673 |
| P304 | page(s) | 7088-7092 | |
| P577 | publication date | 1999-06-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice | |
| P478 | volume | 96 |
| Q88618163 | 40 YEARS of IGF1: Understanding the tissue-specific roles of IGF1/IGF1R in regulating metabolism using the Cre/loxP system |
| Q36190743 | A botulinum toxin-derived targeted secretion inhibitor downregulates the GH/IGF1 axis |
| Q34445166 | A circadian gene expression atlas in mammals: implications for biology and medicine |
| Q43262559 | A general IGF-I overexpression effectively rescued somatic growth and bone deficiency in mice caused by growth hormone receptor knockout |
| Q35080575 | A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liver-derived IGF-I. |
| Q48710597 | A peak in gh-receptor expression is associated with growth activation in Atlantic salmon vertebrae, while upregulation of igf-I receptor expression is related to increased bone density. |
| Q33988381 | Abnormal changes in NKT cells, the IGF-1 axis, and liver pathology in an animal model of ALS. |
| Q34755080 | Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2. |
| Q30436230 | Acromegaly and serum insulin-like growth factor I. |
| Q45870217 | Acromegaly in a hemophilic patient infected with the hepatitis C and human immunodeficiency viruses |
| Q27335370 | Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1 |
| Q53864041 | Age-dependent onset of liver-specific IGF-I gene deficiency and its persistence in old age: implications for postnatal growth and insulin resistance in LID mice. |
| Q38596695 | Aging Effects on Cardiac Progenitor Cell Physiology |
| Q42456812 | Allogeneic bone marrow transplantation restores IGF-I production and linear growth in a gamma-SCID patient with abnormal growth hormone receptor signaling |
| Q56747899 | Altered levels of circulating insulin-like growth factor I (IGF-I) following ischemic stroke are associated with outcome - a prospective observational study |
| Q41121826 | Altered paracrine signaling from the injured knee joint impairs postnatal long bone growth |
| Q49022188 | An experimental model of partial insulin-like growth factor-1 deficiency in mice |
| Q38079231 | Anabolic effects of IGF-1 signaling on the skeleton |
| Q36445136 | Angiotensin II as candidate of cardiac cachexia |
| Q46421323 | Antisense and sense RNA probe hybridization to immobilized crude cellular lysates: a tool to screen growth hormone antagonists |
| Q36092731 | Antitumorigenic actions of growth hormone-releasing hormone antagonists |
| Q41867706 | Arginine deficiency causes runting in the suckling period by selectively activating the stress kinase GCN2. |
| Q89655484 | Associations between prenatal serum levels of leptin, IGF-I, and estradiol and adolescent mothers' height gain during and after pregnancy |
| Q91729381 | Associations between serum levels of insulin-like growth factor-I and bone mineral acquisition in pubertal children: a 3-year follow-up study in Hamamatsu, Japan |
| Q33868147 | Astragalus Extract Mixture HT042 Increases Longitudinal Bone Growth Rate by Upregulating Circulatory IGF-1 in Rats |
| Q54590411 | Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle. |
| Q45899514 | Biochemical markers of recombinant human insulin-like growth factor-I (rhIGF-I)/rhIGF binding protein-3 (rhIGFBP-3) misuse in athletes. |
| Q34207694 | Biological effects of growth hormone and its antagonist |
| Q38091011 | Body size regulation and insulin-like growth factor signaling |
| Q34457990 | Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5. |
| Q43890518 | Bone phenotype of the aromatase deficient mouse |
| Q34647846 | Both low and high serum IGF-1 levels associate with increased risk of cardiovascular events in elderly men |
| Q35141396 | Brain repair and neuroprotection by serum insulin-like growth factor I. |
| Q28564447 | Burn-induced changes in IGF-I and IGF-binding proteins are partially glucocorticoid dependent |
| Q50611250 | CCAAT-enhancer binding protein (C/EBP) β regulates insulin-like growth factor (IGF) 1 expression in porcine liver during prenatal and postnatal development. |
| Q37762345 | CSF-1, IGF-1, and the control of postnatal growth and development |
| Q38110517 | Calcium signaling in the liver |
| Q36911630 | Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice |
| Q38509926 | Cellular Interplay between Cardiomyocytes and Nonmyocytes in Cardiac Remodeling. |
| Q96136852 | Cellular and Molecular Biomarkers Indicate Premature Aging in Pseudoxanthoma Elasticum Patients |
| Q81235261 | Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects |
| Q36849036 | Central and peripheral actions of somatostatin on the growth hormone-IGF-I axis |
| Q33403060 | Characterization of SV-40 Tag rats as a model to study prostate cancer |
| Q35210502 | Circulating free insulin-like growth-factor-I (IGF-I) levels should also be measured to estimate the IGF-I bioactivity |
| Q32062012 | Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus. |
| Q43586173 | Circulating levels of insulin-like growth factors and their binding proteins in patients with chronic liver disease: lack of correlation with bone mineral density |
| Q64085218 | Combined antenatal and postnatal steroid effects on fetal and postnatal growth, and neurological outcomes in neonatal rats |
| Q35731942 | Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid. |
| Q34540094 | Conditional alleles in mice: practical considerations for tissue-specific knockouts |
| Q34389488 | Conditional control of gene expression in the mouse |
| Q34046618 | Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion |
| Q33865210 | Conditional knockout of mouse insulin-like growth factor-1 gene using the Cre/loxP system |
| Q78493468 | Contribution of circulating IGF-I to wound repair in GH-treated rats |
| Q55042287 | Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate. |
| Q33735931 | Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling |
| Q36183694 | Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF production |
| Q89187284 | Deletion of muscle IGF-I transiently impairs growth and progressively disrupts glucose homeostasis in male mice |
| Q46111019 | Diet effects on weight gain and body composition in high growth (hg/hg) mice |
| Q37648847 | Differential Effects of Hormones on Cellular Metabolism in Keratoconus In Vitro |
| Q28564997 | Differential regulation of Shc adaptor proteins in skeletal muscle, spinal cord and forebrain of aged rats with sensorimotor impairment |
| Q55516384 | Differential tissue response to growth hormone in mice. |
| Q35783020 | Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression |
| Q34197808 | Direct stimulation of bone mass by increased GH signalling in the osteoblasts of Socs2-/- mice |
| Q44865051 | Discordant regulation of hepatic IGF-I mRNA and circulating IGF-I during compensatory growth in a teleost, the hybrid striped bass (Morone chrysopsxMorone saxatilis). |
| Q33285460 | Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice |
| Q78556233 | Distribution of insulin-like growth factor-I mRNA in the mandibular condyle and rib cartilage of the rat during growth |
| Q35838980 | Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels |
| Q54614762 | Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling. |
| Q34158496 | Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on hormones of energy balance in a TCDD-sensitive and a TCDD-resistant rat strain |
| Q52148370 | Effect of Deletion of Ghrelin-O-Acyltransferase on the Pulsatile Release of Growth Hormone in Mice. |
| Q34043294 | Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis |
| Q51535883 | Effect of refeeding on IGFI, IGFII, IGF receptors, FGF2, FGF6, and myostatin mRNA expression in rainbow trout myotomal muscle. |
| Q74287154 | Effects of 36 hour fasting on GH/IGF-I axis and metabolic parameters in patients with simple obesity. Comparison with normal subjects and hypopituitary patients with severe GH deficiency |
| Q64103317 | Effects of Eleutherococcus Extract Mixture on Endochondral Bone Formation in Rats |
| Q35667543 | Effects of GH and insulin-like growth factor-I on body composition. |
| Q50909648 | Effects of Phlomis umbrosa Root on Longitudinal Bone Growth Rate in Adolescent Female Rats. |
| Q73689729 | Effects of aging and caloric restriction on IGF-I, IGF-I receptor, IGFBP-3 and IGFBP-4 gene expression in the rat stomach and colon |
| Q74038401 | Effects of aging on expression of genes involved in regulation of proliferation and apoptosis in the colonic epithelium |
| Q43890250 | Effects of aging on hepatic IGF-I signaling |
| Q36123274 | Effects of combined maternal administration with alpha-ketoglutarate (AKG) and β-hydroxy-β-methylbutyrate (HMB) on prenatal programming of skeletal properties in the offspring. |
| Q42376436 | Effects of exogenous growth hormone administration on dexamethasone-induced growth impairment in adolescent male rats |
| Q91245669 | Effects of food deprivation on plasma insulin-like growth factor-1 (Igf1) and Igf binding protein (Igfbp) gene transcription in juvenile cabezon (Scorpaenichthys marmoratus) |
| Q74775077 | Effects of insulin-like growth factors (IGF-I and -II) on growth hormone and prolactin release and gene expression in euryhaline tilapia, Oreochromis mossambicus |
| Q46497787 | Effects of short-term acid and aluminum exposure on the parr-smolt transformation in Atlantic salmon (Salmo salar): disruption of seawater tolerance and endocrine status |
| Q33519034 | Effects of taurine supplementation on bone mineral density in ovariectomized rats fed calcium deficient diet |
| Q33966276 | Elevated levels of hepatocyte nuclear factor 3beta in mouse hepatocytes influence expression of genes involved in bile acid and glucose homeostasis |
| Q46526871 | Endocrine disruption of parr-smolt transformation and seawater tolerance of Atlantic salmon by 4-nonylphenol and 17beta-estradiol. |
| Q33618488 | Endogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohn's disease |
| Q42928419 | Englitazone administration to late pregnant rats produces delayed body growth and insulin resistance in their fetuses and neonates. |
| Q46932793 | Estrogen effects on skeletal muscle insulin-like growth factor 1 and myostatin in ovariectomized rats |
| Q46462885 | Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice |
| Q35207442 | Excitation‐transcription coupling in skeletal muscle: the molecular pathways of exercise |
| Q33884308 | Expression Profiles of the Insulin-like Growth Factor System Components in Liver Tissue during Embryonic and Postnatal Growth of Erhualian and Yorkshire Reciprocal Cross F1 Pigs. |
| Q46770142 | Expression analysis of hypothalamic and pituitary components of the growth hormone axis in fasted and streptozotocin-treated neuropeptide Y (NPY)-intact (NPY+/+) and NPY-knockout (NPY-/-) mice |
| Q93012952 | Fetal malnutrition-induced catch up failure is caused by elevated levels of miR-322 in rats |
| Q47715344 | GH, IGF-I and GH receptors mRNA expression in response to growth impairment following a food deprivation period in individually housed cichlid fish Cichlasoma dimerus |
| Q36888642 | GH/IGF-I axis in anorexia nervosa |
| Q41582800 | GTPase ARFRP1 is essential for normal hepatic glycogen storage and insulin-like growth factor 1 secretion |
| Q35972326 | Genetic Defects in the Growth Hormone-IGF-I Axis Causing Growth Hormone Insensitivity and Impaired Linear Growth |
| Q36808291 | Genomic dissection of the cytokine-controlled STAT5 signaling network in liver |
| Q36993617 | Ghrelin and bone. |
| Q74208906 | Ghrelin gene expression is age-dependent and influenced by gender and the level of circulating IGF-I |
| Q28140549 | Gigantism in mice lacking suppressor of cytokine signalling-2 |
| Q37092115 | Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth |
| Q34158378 | Growth Hormone Releasing Hormone (GHRH) and the GHRH Receptor. |
| Q52684487 | Growth Hormone Research Society perspective on biomarkers of GH action in children and adults. |
| Q58305167 | Growth and Tissue Accretion Rates of Swine Expressing an Insulin-like Growth Factor I Transgene |
| Q44424252 | Growth factor messenger RNA levels in muscle and liver of steroid-implanted and nonimplanted steers1,2 |
| Q32026861 | Growth hormone and the heart |
| Q77148152 | Growth hormone increases the total number of cardiac myocyte nuclei in young rats but not in old rats |
| Q54453415 | Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis. |
| Q79157073 | Growth hormone substitution increases gene expression of members of the IGF family in cortical bone from women with adult onset growth hormone deficiency-relationship with bone turn-over |
| Q34010760 | Growth hormone, IGF-I and insulin and their abuse in sport. |
| Q37484575 | Growth hormone-activated STAT5 may indirectly stimulate IGF-I gene transcription through HNF-3{gamma}. |
| Q37500569 | Growth hormone: does it have a therapeutic role in fracture healing? |
| Q64272032 | Growth signaling and longevity in mouse models |
| Q28504728 | Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels |
| Q36151062 | Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria |
| Q51538721 | Hepatic reduction of insulin-like growth factor (IGF)-I and IGF binding protein-3 that results from fasting is not attenuated in genetically obese rats. |
| Q33569163 | Hormone replacement therapy and physical function in healthy older men. Time to talk hormones? |
| Q34422481 | Human GH receptor-IGF-1 receptor interaction: implications for GH signaling. |
| Q47366049 | Human IGF-I propeptide A promotes articular chondrocyte biosynthesis and employs glycosylation-dependent heparin binding |
| Q26822806 | Human conditions of insulin-like growth factor-I (IGF-I) deficiency |
| Q37149891 | IGF ligand and receptor regulation of mammary development |
| Q44867995 | IGF-I and branchial IGF receptor expression and localization during salinity acclimation in striped bass |
| Q52892182 | IGF-I contributes to glucose homeostasis in the Berlin Fat Mouse Inbred line. |
| Q37323927 | IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner |
| Q51377403 | IGF-I/PI3K/Akt and IGF-I/MAPK/ERK pathways in vivo in skeletal muscle are regulated by nutrition and contribute to somatic growth in the fine flounder. |
| Q34966710 | IGF-binding protein-2 protects against the development of obesity and insulin resistance |
| Q42694058 | IGF1 mRNA splicing variants in Liaoning cashmere goat: identification, characterization, and transcriptional patterns in skin and visceral organs |
| Q34159954 | IGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice |
| Q42462619 | IGFBP-3 activates TGF-beta receptors and directly inhibits growth in human intestinal smooth muscle cells |
| Q52112602 | IL-6-overexpression brings about growth impairment potentially through a GH receptor defect. |
| Q44176902 | Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice |
| Q40158298 | Implication for the regulation of catabolism drawn from the single insulin-like growth factor binding domain protein (SIBD) gene in the mud crab, Scylla paramamosain |
| Q44250008 | In vivo imaging of transcriptionally active estrogen receptors. |
| Q24681712 | Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor system |
| Q33793116 | Increase in insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 1 after supplementation with selenium and coenzyme Q10. A prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens |
| Q36932816 | Increased diet-induced fatty streak formation in female mice with deficiency of liver-derived insulin-like growth factor-I. |
| Q41126209 | Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF-1. |
| Q52572805 | Independent regulation of skeletal growth by Ihh and IGF signaling. |
| Q38034072 | Inflammation and linear bone growth: the inhibitory role of SOCS2 on GH/IGF-1 signaling. |
| Q41779127 | Influence of The -202 A/C insulin-like growth factor-binding protein-3 promoter polymorphism on individual variation in height in Korean girls |
| Q47964044 | Influence of varying degrees of malnutrition on IGF-I expression in the rat diaphragm |
| Q43937867 | Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis |
| Q38974337 | Insulin injection restored increased insulin receptor substrate (IRS)-2 protein during short-term protein restriction but did not affect reduced insulin-like growth factor (IGF)-I mRNA or increased triglyceride accumulation in the liver of rats. |
| Q37672148 | Insulin-Like Growth Factor-1 Deficiency and Cirrhosis Establishment |
| Q40618620 | Insulin-like Growth Factor-1 Rescues the Mutated FGF Receptor 3 (G380R) Expressing ATDC5 Cells From Apoptosis Through Phosphatidylinositol 3-Kinase and MAPK |
| Q34158381 | Insulin-like growth factor (IGF)-I gene deletion |
| Q80152606 | Insulin-like growth factor I (IGF-I) in a growth-enhanced transgenic (GH-overexpressing) bony fish, the tilapia (Oreochromis niloticus): indication for a higher impact of autocrine/paracrine than of endocrine IGF-I |
| Q36449180 | Insulin-like growth factor I is required for vessel remodeling in the adult brain |
| Q36068037 | Insulin-like growth factor I levels in healthy children |
| Q44399900 | Insulin-like growth factor I prevents corticosteroid-induced diaphragm muscle atrophy in emphysematous hamsters |
| Q38294262 | Insulin-like growth factor I regulates apoptosis in condylar cartilage |
| Q34074077 | Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms |
| Q38128225 | Insulin-like growth factor-I (IGF-I) misuse in athletes and potential methods for detection. |
| Q37192175 | Insulin-like growth factor-I (rhIGF-I) therapy of short stature |
| Q47622877 | Insulin-like growth factor-I increases astrocyte intercellular gap junctional communication and connexin43 expression in vitro |
| Q52329568 | Insulin-like growth factors: actions on the skeleton. |
| Q28574698 | Insulin-responsive nuclear proteins facilitate Sp1 interactions with the insulin-like growth factor-I gene |
| Q34767957 | Interactions between GH, IGF-I, glucocorticoids, and thyroid hormones during skeletal growth |
| Q30307314 | Interactive regulation of postmenopausal growth hormone insulin-like growth factor axis by estrogen and growth hormone-releasing peptide-2. |
| Q52653648 | Intermittent hypoxia suppression of growth hormone and insulin-like growth factor-I in the neonatal rat liver. |
| Q28302932 | Investigational agents for the treatment of growth hormone-insensitivity syndrome |
| Q42494351 | Involvement of Sp1 in the transcriptional regulation of the rat insulin-like growth factor-1 gene |
| Q37721934 | Is human growth hormone an ergogenic aid? |
| Q96136770 | JAK2-STAT5 signaling is insensitive to porcine growth hormone (pGH) in hepatocytes of neonatal pig |
| Q57593521 | Kidney growth and renal functions under the growth hormone replacement therapy in children |
| Q98159333 | L-carnitine increases cell proliferation and amino acid transporter expression via the activation of insulin-like growth factor I signaling pathway in rat trophoblast cells |
| Q50119776 | Lifelong exercise and locally produced insulin-like growth factor-1 (IGF-1) have a modest influence on reducing age-related muscle wasting in mice. |
| Q35073629 | Liver-derived IGF-I contributes to GH-dependent increases in lean mass and bone mineral density in mice with comparable levels of circulating GH. |
| Q50894799 | Liver-derived IGF-I regulates cortical bone mass but is dispensable for the osteogenic response to mechanical loading in female mice. |
| Q46445892 | Liver-derived IGF-I regulates exploratory activity in old mice |
| Q28742166 | Liver-derived IGF-I regulates mean life span in mice |
| Q34711314 | Liver-derived endocrine IGF-I is not critical for activation of skeletal muscle protein synthesis following oral feeding |
| Q37709205 | Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles |
| Q37338980 | Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism |
| Q36629289 | Liver-specific hepatocyte nuclear factor-4alpha deficiency: greater impact on gene expression in male than in female mouse liver. |
| Q100295022 | Lmod3 promotes differentiation and proliferation of myoblasts via the AKT and ERK pathways respectively |
| Q31929653 | Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle |
| Q57830323 | Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation |
| Q36068064 | Long-term monitoring of insulin-like growth factor I in adult growth hormone deficiency: a critical appraisal. |
| Q44856197 | Long-term skeletal effects of recombinant human growth hormone (rhGH) alone and rhGH combined with alendronate in GH-deficient adults: a seven-year follow-up study |
| Q35080440 | Longevity effect of IGF-1R(+/-) mutation depends on genetic background-specific receptor activation |
| Q92464759 | Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis |
| Q35764581 | Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus |
| Q38156133 | MEAT SCIENCE AND MUSCLE BIOLOGY SYMPOSIUM--mechanism of growth hormone stimulation of skeletal muscle growth in cattle |
| Q39035483 | Macrophage and adipocyte IGF1 maintain adipose tissue homeostasis during metabolic stresses |
| Q37521345 | Macrophages and CSF-1: implications for development and beyond |
| Q34428191 | Measurement of growth hormone, insulin-like growth factor I and their binding proteins: the clinical aspects |
| Q35197903 | Metabolic effects of GH antagonism in patients with acromegaly |
| Q28590546 | Mex3c regulates insulin-like growth factor 1 (IGF1) expression and promotes postnatal growth |
| Q64228210 | MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway |
| Q42212823 | MicroRNA-497 regulates cell proliferation in hepatocellular carcinoma |
| Q34185295 | Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. |
| Q30434197 | Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice |
| Q40891663 | Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting |
| Q39744178 | Myostatin in black Muscovy duck (Cairina moschata): full-length cDNA cloning and age-dependent mRNA expression compared with IGF-I. |
| Q36920317 | Nanomedicines in the treatment of acromegaly: focus on pegvisomant. |
| Q30451424 | Neurodevelopmental effects of insulin-like growth factor signaling |
| Q34380984 | Neuroendocrine aging in men. Andropause and somatopause |
| Q34774448 | Neurohormonal factors in the development of catabolic/anabolic imbalance and cachexia |
| Q47306340 | Normal growth spurt and final height despite low levels of all forms of circulating insulin-like growth factor-I in a patient with acid-labile subunit deficiency |
| Q37258163 | Nutrition, insulin-like growth factor-1 and retinopathy of prematurity |
| Q49074429 | Nutritional regulation of IGF-I expression during brain development in mice |
| Q42450481 | Octreotide represses secretory-burst mass and nonpulsatile secretion but does not restore event frequency or orderly GH secretion in acromegaly |
| Q35740509 | Ontogeny and nutritional manipulation of the hepatic prolactin-growth hormone-insulin-like growth factor axis in the ovine fetus and in neonate and juvenile sheep |
| Q26825444 | Optimizing IGF-I for skeletal muscle therapeutics |
| Q43794364 | Oral estrogen antagonizes the metabolic actions of growth hormone in growth hormone-deficient women |
| Q91893288 | Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans |
| Q90093908 | PAPP-A and the IGF system in atherosclerosis: what's up, what's down? |
| Q42590798 | Partial rescue of growth failure in growth hormone (GH)-deficient mice by a single injection of a double-stranded adeno-associated viral vector expressing the GH gene driven by a muscle-specific regulatory cassette |
| Q30551534 | Pathological impact of SMN2 mis-splicing in adult SMA mice |
| Q99578928 | Peripheral Circulation and Astrocytes Contribute to the MSC-Mediated Increase in IGF-1 Levels in the Infarct Cortex in a dMCAO Rat Model |
| Q49084529 | Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus. |
| Q31106422 | Persistent neurogenesis in the teleost retina: evidence for regulation by the growth-hormone/insulin-like growth factor-I axis. |
| Q55514337 | Physical exercise, IGF-1 and cognition A systematic review of experimental studies in the elderly. |
| Q64951961 | Pregnancy-associated plasma protein-aa supports hair cell survival by regulating mitochondrial function. |
| Q36766444 | Primer: molecular tools used for the understanding of endocrinology. |
| Q44483053 | Production of insulin-like growth factor binding-proteins by bovine adrenomedullary cells: differential regulation by IGF-I and dexamethasone |
| Q39281051 | Progranulin compensates for blocked IGF-1 signaling to promote myotube hypertrophy in C2C12 myoblasts via the PI3K/Akt/mTOR pathway |
| Q37640165 | Protective effect of maternal uteroplacental insufficiency on oxygen-induced retinopathy in offspring: removing bias of premature birth |
| Q33988826 | Proteoglycan 4: a dynamic regulator of skeletogenesis and parathyroid hormone skeletal anabolism |
| Q27638922 | Rapid identification of small binding motifs with high-throughput phage display: discovery of peptidic antagonists of IGF-1 function |
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| Q36736100 | Regulation of muscle mass by growth hormone and IGF-I. |
| Q36734567 | Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models. |
| Q35128706 | Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models |
| Q39398574 | Regulation of skeletal muscle growth in fish by the growth hormone--insulin-like growth factor system |
| Q35567773 | Regulation of somatic growth by the p160 coactivator p/CIP |
| Q37888841 | Regulatory functions of insulin-like growth factor binding proteins in osteoarthritis. |
| Q92610294 | Regulatory mechanisms involved in muscle and bone remodeling during refeeding in gilthead sea bream |
| Q54537797 | Relative cardiac expression of growth hormone receptor and insulin-like growth factor-I mRNA in congenital heart disease. |
| Q28074486 | Respiratory manifestations in endocrine diseases |
| Q40462437 | Role of G protein-coupled receptors (GPCR), matrix metalloproteinases 2 and 9 (MMP2 and MMP9), heparin-binding epidermal growth factor-like growth factor (hbEGF), epidermal growth factor receptor (EGFR), erbB2, and insulin-like growth factor 1 recep |
| Q52341096 | Role of IGF-I and Efn-Eph Signaling in Skeletal Metabolism. |
| Q33988273 | Role of IGF-I and the TNFα/NF-κB pathway in the induction of muscle atrogenes by acute inflammation |
| Q28082188 | Role of IGF-I signaling in muscle bone interactions |
| Q37673466 | Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone. |
| Q38006439 | Role of insulin-like growth factor-1 in the regulation of skeletal growth |
| Q80060734 | Role of the GH/IGF-I axis in the growth retardation of weaver mice |
| Q36268989 | SIRT6 deficiency culminates in low-turnover osteopenia |
| Q36573963 | SOCS2 Balances Metabolic and Restorative Requirements during Liver Regeneration |
| Q44677007 | SOCS2 is the critical regulator of GH action in murine growth plate chondrogenesis |
| Q92242450 | Seasonal expressions of growth hormone receptor, insulin-like growth factor 1 and insulin-like growth factor 1 receptor in the scented glands of the muskrats (Ondatra zibethicus) |
| Q50202272 | Secretion pathway of liver IGF-1 via JAK2/STAT3 in chick embryo under the monochromatic light |
| Q46209315 | Serum IGF-I-deficiency does not prevent compensatory skeletal muscle hypertrophy in resistance exercise |
| Q40282159 | Serum from heifer calves treated with bovine growth hormone affects the rate of proliferation of C2C12 myogenic cells dependent on the plane of nutrition: the role of insulin-like growth factor-I and IGF-binding proteins-2 and -3. |
| Q34265977 | Serum growth factors and neuroprotective surveillance: focus on IGF-1. |
| Q35197911 | Serum levels of insulin-like growth factor I and its binding proteins in health and disease |
| Q37268108 | Sex differences in the expression of hepatic drug metabolizing enzymes |
| Q39527508 | Skeletal effects of growth hormone and insulin-like growth factor-I therapy. |
| Q42429798 | Smaller cardiac cell size and reduced extra-cellular collagen might be beneficial for hearts of Ames dwarf mice |
| Q39580270 | Smooth Muscle Insulin-Like Growth Factor-1 Mediates Hypoxia-Induced Pulmonary Hypertension in Neonatal Mice |
| Q42016953 | Spatiotemporal patterns of IGF-like peptide expression in the silkmoth Bombyx mori predict its pleiotropic actions |
| Q52165213 | Stability of alternatively spliced IGF-I mRNA in growth plate chondrocytes. |
| Q35055523 | Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis |
| Q53327999 | Still more questions than answers: report on the 5th International Symposium on Insulin-like Growth Factors, Brighton, UK, 31 October-4 November 1999. |
| Q52709053 | Structure and Function of Bone Marrow Adipocytes. |
| Q33951057 | Targeting insulin-like growth factor axis in hepatocellular carcinoma |
| Q36149431 | Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathway |
| Q33218146 | The COMT val158met polymorphism is associated with early pubertal development, height and cortical bone mass in girls |
| Q34182483 | The GH-IGF-SST system in hepatocellular carcinoma: biological and molecular pathogenetic mechanisms and therapeutic targets |
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| Q38097351 | The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations |
| Q51766789 | The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects. |
| Q33918694 | The IGF axis and hepatocarcinogenesis |
| Q37064809 | The IGF axis and placental function. a mini review |
| Q38403875 | The IGF-1/Akt/S6 pathway and expressions of glycolytic myosin heavy chain isoforms are upregulated in chicken skeletal muscle during the first week after hatching. |
| Q36715210 | The Regulation of IGF-1 Gene Transcription and Splicing during Development and Aging |
| Q90267521 | The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle |
| Q40970747 | The association between skeletal maturation and adrenal androgen levels in obese children and adolescents. |
| Q35259498 | The characteristics of the porcine (Sus scrofa) liver miRNAome with the use of next generation sequencing. |
| Q51671552 | The decrease in mature myostatin protein in male skeletal muscle is developmentally regulated by growth hormone. |
| Q92683638 | The effect of a maternal meal on fetal liver blood flow |
| Q48094574 | The effects of recombinant bovine somatotropin (rbST) on tissue IGF-I, IGF-I receptor, and GH mRNA levels in rainbow trout, Oncorhynchus mykiss. |
| Q39432413 | The emerging role of alternative splicing in senescence and aging. |
| Q37039560 | The hormonal action of IGF1 in postnatal mouse growth |
| Q47988260 | The influence of undernutrition during gestation on skeletal muscle cellularity and on the expression of genes that control muscle growth |
| Q36892287 | The insulin-like growth factor system and the fetal brain: effects of poor maternal nutrition |
| Q36468522 | The insulin-like growth factor system in chronic kidney disease: Pathophysiology and therapeutic opportunities |
| Q34155259 | The reciprocal regulation of gamma-synuclein and IGF-I receptor expression creates a circuit that modulates IGF-I signaling. |
| Q35971522 | The role of IGF-1 for fracture risk in men. |
| Q37082951 | The role of IGF-I and its binding proteins in the development of type 2 diabetes and cardiovascular disease |
| Q35690633 | The role of PAPP-A in the IGF system: location, location, location. |
| Q36563733 | The role of insulin-like growth factor-I and growth factor-associated signal transduction pathways in estradiol and progesterone facilitation of female reproductive behaviors |
| Q37381848 | The role of liver-derived insulin-like growth factor-I. |
| Q35937545 | The splicing of the IGF-I gene to yield different muscle growth factors |
| Q47722433 | The utility of the IGF-I generation test in children with chronic kidney disease |
| Q43078115 | Therapeutic options in the management of acromegaly: focus on lanreotide Autogel |
| Q44303529 | Thyroid hormone stimulates hepatic IGF-I mRNA expression in a bony fish, the tilapia Oreochromis mossambicus, in vitro and in vivo |
| Q43545218 | Time course changes in IGFBP-1 after treadmill exercise and postexercise food intake in rats |
| Q34608704 | Transgenic systems in drug discovery: from target identification to humanized mice |
| Q50126031 | Treatment of adult growth hormone deficiency with human recombinant growth hormone: an update on current evidence and critical review of advantages and pitfalls |
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| Q37389048 | aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues |
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