Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up

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Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up is …
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P356DOI10.1210/ER.2015-1048
P932PMC publication ID4702496
P698PubMed publication ID26485225

P50authorAlberto Roselló-DíezQ64089329
P2093author name stringAlexandra L Joyner
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Homozygous deletion of the human insulin receptor gene results in leprechaunismQ24311628
LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in miceQ24316352
Fibroblast growth factor receptor 3 is a negative regulator of bone growthQ24322706
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunctionQ24322907
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formationQ24600279
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Mechanical tension-stress induces expression of bone morphogenetic protein (BMP)-2 and BMP-4, but not BMP-6, BMP-7, and GDF-5 mRNA, during distraction osteogenesisQ28566983
Connective tissue growth factor and insulin-like growth factor 2 show upregulation in early growth plate radiorecovery response following irradiationQ28569346
Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilageQ28571441
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18Q28584951
Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehogQ28586013
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FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopodQ28592971
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FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescenceQ28975455
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Developmental regulation of the growth plateQ29618969
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)Q29619910
Role of insulin-like growth factors in embryonic and postnatal growthQ29620034
Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1Q30417692
Postnatal growth after intrauterine growth restriction alters central leptin signal and energy homeostasisQ31047289
Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in miceQ33285460
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Chondrocytes transdifferentiate into osteoblasts in endochondral bone during development, postnatal growth and fracture healing in miceQ34633873
Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growthQ34650896
Cyclic dermal BMP signalling regulates stem cell activation during hair regenerationQ34737529
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locusQ34776140
Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female miceQ34849712
Endospanins regulate a postinternalization step of the leptin receptor endocytic pathwayQ34979041
The paracrine feedback loop between vitamin D₃ (1,25(OH)₂D₃) and PTHrP in prehypertrophic chondrocytesQ34984051
Catch-up growth: definition, mechanisms, and modelsQ35037999
The dangerous road of catch-up growth.Q35058374
Return of the chalonesQ35065941
Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of beta-catenin signalingQ35069746
Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling.Q35096652
Nuclear factor-kappaB (NF-kappaB) p65 interacts with Stat5b in growth plate chondrocytes and mediates the effects of growth hormone on chondrogenesis and on the expression of insulin-like growth factor-1 and bone morphogenetic protein-2Q35107411
Preclinical studies on mesenchymal stem cell-based therapy for growth plate cartilage injury repairQ35130994
Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathwayQ35236207
Distinct germline progenitor subsets defined through Tsc2-mTORC1 signalingQ35303050
Organ-level quorum sensing directs regeneration in hair stem cell populationsQ35367291
The role of leptin in female adolescenceQ35596206
Dual pathways to endochondral osteoblasts: a novel chondrocyte-derived osteoprogenitor cell identified in hypertrophic cartilageQ35616579
Target of rapamycin (TOR) in nutrient signaling and growth controlQ35620394
Cell polarity: The missing link in skeletal morphogenesis?Q35624653
Insulin exerts direct, IGF-1 independent actions in growth plate chondrocytesQ35755152
Chalones: from aqueous extracts to oligopeptides.Q35869819
Fundamental limits on longitudinal bone growth: growth plate senescence and epiphyseal fusion.Q35893879
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac functionQ35895986
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptideQ35915041
Metabolic consideration of epiphyseal growth: survival responses in a taxing environmentQ35928543
Integrating body and organ size in Drosophila: recent advances and outstanding problemsQ35972040
Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal developmentQ35985042
Insulin-like growth factor ligands, receptors, and binding proteins in cancer.Q36004697
Structural and functional properties of CCN proteinsQ36053014
Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotypeQ36057344
BDNF alters ERK/p38 MAPK activity ratios to promote differentiation in growth plate chondrocytesQ36113810
Effects of estrogen on growth plate senescence and epiphyseal fusionQ36240179
Alterations in the growth plate associated with growth modulation by sustained compression or distractionQ36274923
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liverQ34607172
Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowthQ34622370
Hippo signaling: growth control and beyondQ34625638
Asymmetric flies: the control of developmental noise in Drosophila.Q34631335
Effects of early nutrition intervention on IGF1, IGFBP3, intestinal development, and catch-up growth of intrauterine growth retardation ratsQ80911605
Modulation of vertebral and tibial growth by compression loading: diurnal versus full-time loadingQ81165709
Chalones: chemical regulation of cell divisionQ81192060
Thrifty metabolism that favors fat storage after caloric restriction: a role for skeletal muscle phosphatidylinositol-3-kinase activity and AMP-activated protein kinaseQ81421036
Lack of telomere shortening with age in mouse resting zone chondrocytesQ81585060
Catch-up growth: testing the hypothesis of delayed growth plate senescence in humansQ81630630
Bone growth in paralyzed limbsQ82091792
Nuclear receptor-dependent bile acid signaling is required for normal liver regenerationQ83154070
The effect of roentgen irradiation on epiphyseal growth experimental studies upon the dogQ83283826
Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in miceQ83533646
Regulative patterning in limb bud transplants is induced by distalizing activity of apical ectodermal ridge signals on host limb cellsQ83921732
Effects of hind limb unloading and reloading on nitric oxide synthase expression and apoptosis of osteocytes and chondrocytesQ83963479
Russell–Silver syndromeQ84966066
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Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin,Q38319405
Leptin regulates chondrocyte differentiation and matrix maturation during endochondral ossificationQ38323319
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitorsQ38329519
Leptin synergizes with thyroid hormone signaling in promoting growth plate chondrocyte proliferation and terminal differentiation in vitroQ38337121
Organ-Size Regulation in MammalsQ38549724
The critical role of the epidermal growth factor receptor in endochondral ossification.Q38810753
FGF23 suppresses chondrocyte proliferation in the presence of soluble α-Klotho both in vitro and in vivoQ39227211
YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29Q39246531
Interference by adrenaline with chondrogenic differentiation through suppression of gene transactivation mediated by Sox9 family members.Q39506093
Hepatic branch vagotomy can suppress liver regeneration in partially hepatectomized ratsQ39665504
Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cellsQ39804680
The Natural History of the Silver-Russell Syndrome: A Longitudinal Study of Thirty-nine CasesQ39944787
Positional Information in Chick Limb MorphogenesisQ39955273
Compensatory adrenal growth: a neurally mediated reflexQ40012256
mTOR signaling contributes to chondrocyte differentiationQ40014562
Allometry and size in ontogeny and phylogenyQ40052889
The neural regulation of compensatory adrenal growthQ40175848
mTORC2 regulates cardiac response to stress by inhibiting MST1.Q40182849
The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines.Q40285708
Suppressor of cytokine signaling-2 limits intestinal growth and enterotrophic actions of IGF-I in vivoQ40297806
The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cellsQ40308810
Hormonal and nutritional regulation of IGF-I and its binding proteinsQ40397983
ACTH enhances chondrogenesis in multipotential progenitor cells and matrix production in chondrocytes.Q40543323
Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cellsQ40559771
Transplantation of epiphyseal plate allografts between animals of different agesQ40812161
The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteinsQ41093857
The role of periosteal tension in the growth of long bonesQ41450968
The bone and beyond: 'Dem bones' are made for more than walking.Q41574661
Bioelectric signaling regulates size in zebrafish finsQ41876070
"Dead Cells Talking": The Silent Form of Cell Death Is Not so Quiet.Q41981106
Noncanonical frizzled signaling regulates cell polarity of growth plate chondrocytesQ42109218
Endochondral growth in growth plates of three species at two anatomical locations modulated by mechanical compression and tensionQ42129285
Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fracturesQ42202564
Insulin is a mitogen for isolated epiphyseal growth plate chondrocytes from the fetal lambQ42481155
IGF and IGF-binding protein expression in the growth plate of normal, dexamethasone-treated and human IGF-II transgenic miceQ42526869
The Growth in Length of the Long Bones in the Madder-fed Pig.Q42561938
β2-adrenergic receptors inhibit the expression of collagen type II in growth plate chondrocytes by stimulating the AP-1 factor Jun-B.Q42774029
Regulation of chick bone growth by leptin and catecholaminesQ43121762
Patterns of catch-up growthQ43478556
Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf miceQ43640386
Bone phenotype of the aromatase deficient mouseQ43890518
Osteocytic canalicular networks: morphological implications for altered mechanosensitivityQ43995302
Rickets in VDR null mice is secondary to decreased apoptosis of hypertrophic chondrocytesQ44112941
Cartilage sulfation during catch-up growth after fasting in ratsQ44136007
Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiationQ44166152
Runx2 expression and action in chondrocytes are regulated by retinoid signaling and parathyroid hormone-related peptide (PTHrP).Q44264957
Regulation by growth hormone of number of chondrocytes containing IGF-I in rat growth plateQ44327491
Increased bone mass, altered trabecular architecture and modified growth plate organization in the growing skeleton of SOCS2 deficient mice.Q44357317
Molecular pathways mediating mechanical signaling in boneQ36345286
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in miceQ36392687
Normal growth and development in the absence of hepatic insulin-like growth factor IQ36394699
Vitamin D physiologyQ36430932
IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathwayQ36488507
Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopeciaQ36576317
Development of the endochondral skeletonQ36629738
BMP signaling in the cartilage growth plate.Q36659526
Thyroid hormone and the growth plateQ36698197
Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease.Q36701486
Multiple phases of chondrocyte enlargement underlie differences in skeletal proportionsQ36711346
Role of CCN2/CTGF/Hcs24 in bone growthQ36729090
Small for gestational age: short stature and beyondQ36745231
Roles of epidermal growth factor family in the regulation of postnatal somatic growth.Q36745234
An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organsQ36808158
Expression of multiple insulin and insulin-like growth factor receptor genes in salmon gill cartilageQ36816503
Size and shape: the developmental regulation of static allometry in insects.Q36824800
Histomorphometric evidence of growth plate recovery potential after fractionated radiotherapy: an in vivo modelQ36916881
Mitogenic signaling pathways induced by G protein-coupled receptorsQ36929839
The growth hormone-insulin-like growth factor-I axis in chronic kidney diseaseQ36934464
Inhibition of growth hormone signaling by the fasting-induced hormone FGF21.Q36953853
Endocrine functions of bone in mineral metabolism regulation.Q36982323
FGFR3 and FGFR4 do not mediate renal effects of FGF23.Q36985772
GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activationQ37000953
Insulin-like growth factor-binding proteins and bone metabolismQ37001115
Natriuretic peptide C receptor signalling in the heart and vasculatureQ37002318
CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stressQ37004735
In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasisQ37072412
Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair.Q37076212
Myostatin (GDF-8) inhibits chondrogenesis and chondrocyte proliferation in vitro by suppressing Sox-9 expressionQ37081618
Contrasting bone effects of temporary versus permanent IGFBP administration in rodentsQ37097561
Leptin and regulation of linear growthQ37135141
An extensive genetic program occurring during postnatal growth in multiple tissuesQ37136956
let-7 and miR-140 microRNAs coordinately regulate skeletal development.Q37143645
Iodothyronine deiodinase enzyme activities in bone.Q37189394
SCF, BDNF, and Gas6 are regulators of growth plate chondrocyte proliferation and differentiationQ33576515
Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in miceQ33602622
Neuroendocrine control of growth hormone secretionQ33604638
mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cellsQ33609242
Compensatory cellular hypertrophy: the other strategy for tissue homeostasis.Q33616271
Growth retardation in children with chronic renal failureQ33734624
Some Unexpected Results of the Heteroplastic Transplantation of LimbsQ33763581
Regulation by fasting of rat insulin-like growth factor I and its receptor. Effects on gene expression and bindingQ33848600
MicroRNA-140 plays dual roles in both cartilage development and homeostasisQ33885698
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinaseQ33890035
Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesisQ33902251
Genetic disorders of the skeleton: a developmental approachQ33906292
Distribution of slow-cycling cells in epiphyseal cartilage and requirement of β-catenin signaling for their maintenance in growth plateQ33964899
Catch-up growth: possible mechanismsQ33982207
Is bone a target-tissue for the nervous system? New advances on the understanding of their interactionsQ33997030
Coordinated postnatal down-regulation of multiple growth-promoting genes: evidence for a genetic program limiting organ growth.Q34017146
Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretionQ34046618
Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formationQ34083023
mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.Q34129574
The somatomedin hypothesis: 2001.Q34131694
G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytesQ34132200
GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male miceQ34132870
Leptin regulates bone formation via the sympathetic nervous systemQ34157988
Height and occupational success: a review and critiqueQ34173315
MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4.Q34209593
Endogenous retinoids in mammalian growth plate cartilage: analysis and roles in matrix homeostasis and turnoverQ34299146
The effect of physical height on workplace success and income: preliminary test of a theoretical modelQ34322798
Nutritional regulation of the insulin-like growth factorsQ34339433
Mechanical activation of mammalian target of rapamycin pathway is required for cartilage developmentQ34365539
Multiple melanocortin receptors are expressed in bone cellsQ34408083
The Fibroblast Growth Factor signaling pathwayQ34467171
A review of crosstalk between MAPK and Wnt signals and its impact on cartilage regenerationQ34527178
Insight into the physiological actions of thyroid hormone receptors from genetically modified miceQ34529692
Increased expression of fibroblast growth factor 21 (FGF21) during chronic undernutrition causes growth hormone insensitivity in chondrocytes by inducing leptin receptor overlapping transcript (LEPROT) and leptin receptor overlapping transcript-likeQ37189525
Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage.Q37199110
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcriptionQ37259684
Striking the balance between PTEN and PDK1: it all depends on the cell contextQ37287601
Thyroid hormone actions in cartilage and boneQ37290960
Signaling cross-talk between TGF-beta/BMP and other pathwaysQ37323342
Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formationQ37352985
Inflammatory cytokines and the GH/IGF-I axis: novel actions on bone growth.Q37426523
Signaling networks and transcription factors regulating mechanotransduction in boneQ37483735
Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental programming.Q37506844
Genetic control of bone formationQ37540138
Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activationQ37622323
A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response.Q37656609
Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organsQ37693870
Wnt and the Wnt signaling pathway in bone development and diseaseQ37724188
Natriuretic peptide system: an overview of studies using genetically engineered animal modelsQ37863198
Receptor tyrosine kinase-G-protein-coupled receptor signalling platforms: out of the shadow?Q37879733
Endocrine regulation of longitudinal bone growthQ37922021
Molecular defects causing skeletal dysplasiasQ37922025
Inflammation and linear bone growth: the inhibitory role of SOCS2 on GH/IGF-1 signaling.Q38034072
Fibroblast growth factor 21 as an emerging metabolic regulator: clinical perspectives.Q38058339
The Hippo superhighway: signaling crossroads converging on the Hippo/Yap pathway in stem cells and developmentQ38073434
The Hippo pathway: regulators and regulationsQ38083640
Beckwith-Wiedemann and Silver-Russell syndromes: opposite developmental imbalances in imprinted regulators of placental function and embryonic growthQ38089794
The paradox of FGFR3 signaling in skeletal dysplasia: why chondrocytes growth arrest while other cells over proliferate.Q38167936
Retinoic acid signaling pathways in development and diseasesQ38176138
A new mechanism for growth hormone receptor activation of JAK2, and implications for related cytokine receptorsQ38237652
Intracellular signaling mechanisms of the melanocortin receptors: current state of the art.Q38287475
TGFbeta and PTHrP control chondrocyte proliferation by activating cyclin D1 expression.Q38294039
Leptin is a potent stimulator of bone growth in ob/ob miceQ38307707
Paralysis and growth of the musculoskeletal system in the embryonic chickQ68613395
Effect of peripheral nerve on limb developmentQ68833174
Studies of long bone growth. I. Determination of differential elongation in paired growth plates of the ratQ68867881
Periosteal division and longitudinal growth in the tibia of the ratQ69447961
Effect of denervation on limb growthQ69735907
Differential expression of insulin-like growth factor-I (IGF-I) and IGF-II messenger ribonucleic acid in growing rat boneQ70577706
Determination of proliferative characteristics of growth plate chondrocytes by labeling with bromodeoxyuridineQ70586359
Catch-up growthQ71086005
Cell cycle analysis of proliferative zone chondrocytes in growth plates elongating at different ratesQ71420377
Control of the limb bud outgrowth in quail-chick chimeraQ71959161
The effect of experimental epiphysiodesis on growth in length of the rabbit's tibiaQ72047802
Beta-receptor blockade by propranolol modifies the effect of the inhibitory, endogenous epidermal pentapeptide on epidermal cell flux at the G2-M transition but not at the G1-S transitionQ72456506
Longitudinal overgrowth of bone after osteotomy in young rats: influence of bone stabilityQ73166922
Expression of cyclin-dependent kinase inhibitors in epiphyseal chondrocytes induced to terminally differentiate with thyroid hormoneQ73274536
Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosteroneQ73315959
Localization of estrogen receptors-alpha and -beta and androgen receptor in the human growth plate at different pubertal stagesQ73375829
Short-term glucocorticoid treatment of prepubertal mice decreases growth and IGF-I expression in the growth plateQ73448977
Interaction of epidermal growth factor and insulin-like growth factor-I in the regulation of growth plate chondrocytesQ73510850
The localization of androgen receptors in human boneQ73785087
Catch-up growthQ73790897
Indian hedgehog is an essential component of mechanotransduction complex to stimulate chondrocyte proliferationQ74244069
Gender differences in expression of androgen receptor in tibial growth plate and metaphyseal bone of the ratQ74252553
Serum leptin concentrations during pregnancy and their relationship to fetal growthQ74277329
Modulation of appositional and longitudinal bone growth in the rat ulna by applied static and dynamic forceQ74363726
Testosterone stimulates insulin-like growth factor-I and insulin-like growth factor-I-receptor gene expression in the mandibular condyle--a model of endochondral ossificationQ74657626
Sex steroid metabolism in the tibial growth plate of the ratQ74805683
Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathwayQ75217684
THE AUTONOMOUS BEHAVIOUR OF NORMAL THYMUS GRAFTSQ76544878
RESTRICTED GROWTH CAPACITY OF MULTIPLE SPLEEN GRAFTSQ76805534
REGULATION OF THE LONGITUDINAL GROWTH OF LONG BONESQ76814705
The effects of dynamic axial loading on the rat growth plateQ77547301
Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient miceQ77678637
Genetics of mouse growthQ77684683
Adrenocorticotropin insensitivity syndromesQ77712276
Expression of thyroid hormone receptor isoforms in rat growth plate cartilage in vivoQ78197613
The effects of the estrogen receptor blocker, Faslodex (ICI 182,780), on estrogen-accelerated bone maturation in miceQ78206740
Enlargement of growth plate chondrocytes modulated by sustained mechanical loadingQ78366827
REGULATION OF EXCESSES AND DEFICIENCIES OF THE WING RUDIMENT OF THE CHICK EMBRYOQ78373278
Changes of bone morphology in response to hindlimb suspension of ratsQ79367619
Nosology and classification of genetic skeletal disorders: 2006 revisionQ79375682
Rapamycin retards growth and causes marked alterations in the growth plate of young ratsQ79977811
Restoration of growth plate function following radiotherapy is driven by increased proliferative and synthetic activity of expansions of chondrocytic clonesQ80135980
Smad4 is required for the normal organization of the cartilage growth plateQ80383784
Serum leptin concentrations in children with mild protein-energy malnutrition and catch-up growthQ80877338
Dexamethasone increases growth hormone receptor messenger ribonucleic acid levels in liver and growth plate.Q52214434
SOCS2 is the critical regulator of GH action in murine growth plate chondrogenesisQ44677007
Temporal changes in PTHrP, Bcl-2, Bax, caspase, TGF-beta, and FGF-2 expression following growth plate irradiation with or without radioprotectantQ44733049
Inactivation of the 25-hydroxyvitamin D 1alpha-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasisQ44739140
The sequence of the hemoregulatory peptide is present in Gi alpha proteinsQ44810124
Minutes: Mutants of Drosophila autonomously affecting cell division rateQ44889355
Serum somatomedin stimulation in thyroxine-treated hypophysectomized ratsQ45261991
BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways.Q45958669
Chondrocyte-specific modulation of Cyp27b1 expression supports a role for local synthesis of 1,25-dihydroxyvitamin D3 in growth plate development.Q45991856
Natural large-scale regeneration of rib cartilage in a mouse model.Q45999374
Neuromedin-U inhibits unilateral adrenalectomy-induced compensatory adrenal growth in the rat.Q46018386
Effect of fasting on insulin-like growth factor-I (IGF-I) and growth hormone receptor mRNA levels and IGF-I gene transcription in rat liverQ46112882
The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized miceQ46195070
Autonomic regulation of liver regeneration after partial hepatectomy in miceQ46487611
Retinoic acid in development: towards an integrated viewQ46549138
Peroxisome proliferator activated receptor-gamma (PPARgamma) represses thyroid hormone signaling in growth plate chondrocytesQ46603665
MITOTIC CONTROL BY INTERNAL SECRETION: THE ROLE OF THE CHALONE-ADRENALIN COMPLEX.Q46663624
Endocrine profile of children with intrauterine growth retardationQ46674606
Beta2-adrenergic receptors expressed on murine chondrocytes stimulate cellular growth and inhibit the expression of Indian hedgehog and collagen type X.Q46866359
Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing.Q47072280
Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation.Q47072549
A longitudinal study of the growth of the New Zealand white rabbit: cumulative and biweekly incremental growth rates for body length, body weight, femoral length, and tibial lengthQ47214931
Insulin-like growth factor-I and growth in height, leg length, and trunk length between ages 5 and 10 yearsQ47339180
REGULATION OF GROWTH IN SIZE IN MAMMALS.Q47423890
Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgroundsQ47645757
Age- and site-specific decline in insulin-like growth factor-I receptor expression is correlated with differential growth plate activity in the mouse hindlimbQ47785593
Central nervous system-specific knockout of Brg1 causes growth retardation and neuronal degenerationQ48099697
Catch-up growth follows an abnormal pattern in experimental renal insufficiency and growth hormone treatment normalizes it.Q48428205
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.Q49042849
Cell competition promotes phenotypically silent cardiomyocyte replacement in the mammalian heart.Q50449935
Shifting linear growth during infancy: illustration of genetic factors in growth from fetal life through infancy.Q50918879
Epiphyseal growth plate growth hormone receptor signaling is decreased in chronic kidney disease-related growth retardation.Q50954759
Leptin reverses the inhibitory effect of caloric restriction on longitudinal growth.Q51534065
Effects of prolonged food deprivation on the ultradian growth hormone rhythm and immunoreactive somatostatin tissue levels in the ratQ51662299
Role of IGF signaling in catch-up growth and accelerated temporal development in zebrafish embryos in response to oxygen availability.Q51890344
Depletion of resting zone chondrocytes during growth plate senescence.Q52020770
Growth plate senescence is associated with loss of DNA methylation.Q52045016
Evidence supporting dual, IGF-I-independent and IGF-I-dependent, roles for GH in promoting longitudinal bone growth.Q52093861
The hypothalamic insulin-like growth factor-1 receptor and its relationship to gonadotropin-releasing hormones neurones during postnatal development.Q52093909
Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation.Q52110044
Catch-up growth is associated with delayed senescence of the growth plate in rabbits.Q52128408
Expression of aromatase in the human growth plate.Q52129401
Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.Q52142765
Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation.Q52143090
A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos.Q52167503
Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy.Q52173480
Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.Q52192889
The developmental skeletal growth in the rat foot is reduced after denervation.Q52194325
Fetal insulin-like growth factor (IGF)-I and IGF-II are regulated differently by glucose or insulin in the sheep fetus.Q52203848
Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.Q52207923
Catch-up growth after glucocorticoid excess: a mechanism intrinsic to the growth plate.Q52213846
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)646-680
P577publication date2015-10-20
P1433published inEndocrine ReviewsQ3054007
P1476titleRegulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up
P478volume36

Reverse relations

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