HUB1, a novel Kruppel type zinc finger protein, represses the human T cell leukemia virus type I long terminal repeat-mediated expression

scientific article published on December 15, 1997

HUB1, a novel Kruppel type zinc finger protein, represses the human T cell leukemia virus type I long terminal repeat-mediated expression is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/25.24.5025
P953full work available at URLhttp://academic.oup.com/nar/article-pdf/25/24/5025/4913405/25-24-5025.pdf
https://academic.oup.com/nar/article-pdf/25/24/5025/4913405/25-24-5025.pdf
https://europepmc.org/articles/PMC147159
https://europepmc.org/articles/PMC147159?pdf=render
P932PMC publication ID147159
P698PubMed publication ID9396811
P5875ResearchGate publication ID13832956

P50authorTakahiko TamuraQ60045022
P2093author name stringK. Okumura
K. Naito
G. Sakaguchi
H. Igarashi
P2860cites workThe human genome contains hundreds of genes coding for finger proteins of the Krüppel typeQ24301305
The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteinsQ24303815
Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A proteinQ24309481
The ht beta gene encodes a novel CACCC box-binding protein that regulates T-cell receptor gene expressionQ24311961
KAP-1, a novel corepressor for the highly conserved KRAB repression domainQ24317676
Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteinsQ24324594
ZNF75: isolation of a cDNA clone of the KRAB zinc finger gene subfamily mapped in YACs 1 Mb telomeric of HPRTQ24328941
Krüppel-associated boxes are potent transcriptional repression domainsQ24563259
The GLI gene encodes a nuclear protein which binds specific sequences in the human genomeQ24598690
ZBP-89, a Krüppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoterQ24647752
Involvement of transcription factor YB-1 in human T-cell lymphotropic virus type I basal gene expressionQ24649585
Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: identification of a new multigene familyQ24651101
C33 antigen recognized by monoclonal antibodies inhibitory to human T cell leukemia virus type 1-induced syncytium formation is a member of a new family of transmembrane proteins including CD9, CD37, CD53, and CD63Q28190659
pEF-BOS, a powerful mammalian expression vectorQ29547606
Structural basis for the binding of proline-rich peptides to SH3 domainsQ29620408
Two cis-acting elements responsible for posttranscriptional trans-regulation of gene expression of human T-cell leukemia virus type I.Q33650651
Tax1 induction of the HTLV-I 21 bp enhancer requires cooperation between two cellular DNA-binding proteinsQ33918902
The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1Q33922049
Isolation of a new type C retrovirus (HTLV) in primary uncultured cells of a patient with Sézary T-cell leukaemiaQ34252853
Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human seraQ34276501
Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domainQ34798810
The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression.Q35238471
Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpressionQ36234059
Sequences downstream of the RNA initiation site regulate human T-cell lymphotropic virus type I basal gene expressionQ36646061
A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I TAX1 with a responsive element in the viral long terminal repeatQ36720321
A new regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1 and cloning of cDNAs encoding its binding proteinsQ36766924
Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I.Q36798336
The retinoblastoma gene product regulates Sp1-mediated transcriptionQ36816438
Human T-cell leukemia virus (HTLV-I) transcripts in fresh and cultured cells of patients with adult T-cell leukemiaQ37571665
Autoantigen Ku protein is involved in DNA binding proteins which recognize the U5 repressive element of human T-cell leukemia virus type I long terminal repeatQ38301372
The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulatorQ38306731
Sp3 represses transcription when tethered to promoter DNA or targeted to promoter proximal RNA.Q38359173
Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesisQ39021217
An inhibitor domain in Sp3 regulates its glutamine-rich activation domains.Q39461480
A Regulatory Element in the Human Interleukin 2 Gene Promoter Is a Binding Site for the Zinc Finger Proteins Sp1 and EGR-1Q39469566
Regulatory anatomy of the murine interleukin-2 geneQ40519016
Heterodimeric Drosophila gap gene protein complexes acting as transcriptional repressorsQ40789545
Sp1-mediated transcriptional activation is repressed by Sp3Q40792899
Binding of the HTLV-I Tax1 transactivator to the inducible 21 bp enhancer is mediated by the cellular factor HEB1.Q41083397
Sp1 family proteins recognize the U5 repressive element of the long terminal repeat of human T cell leukemia virus type I through binding to the CACCC core motifQ41197300
Identification of two distinct elements in the long terminal repeat of HTLV-I responsible for maximum gene expressionQ41333213
Induction of ICAM-1 and LFA-3 by Tax1 of human T-cell leukemia virus type 1 and mechanism of down-regulation of ICAM-1 or LFA-1 in adult-T-cell-leukemia cell linesQ41370649
Synergism between two distinct elements of the HTLV-I enhancer during activation by the trans-activator of HTLV-I.Q41666094
Negative regulation of human c-fos expression by the retinoblastoma gene productQ41724715
Interaction of host cell proteins with the human T-cell leukemia virus type I transcriptional control region. II. A comprehensive map of protein-binding sites facilitates construction of a simple chimeric promoter responsive to the viral tax2 gene pQ41734182
The U5 sequence is a cis-acting repressive element for genomic RNA expression of human T cell leukemia virus type I.Q41735159
Transcriptional suppression of the human T-cell leukemia virus type I long terminal repeat occurs by an unconventional interaction of a CREB factor with the R regionQ42070420
Myb protein binds to multiple sites in the human T cell lymphotropic virus type 1 long terminal repeat and transactivates LTR-mediated expressionQ42091359
CCAAT/enhancer-binding protein delta gene expression is mediated by APRF/STAT3.Q42438828
Characterization of a transcriptional attenuator within the 5' R region of the human T cell leukemia virus type 1.Q42513748
A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene.Q47071606
Drosophila Krüppel protein is a transcriptional repressorQ52449047
Control of transcription by Krüppel through interactions with TFIIB and TFIIE betaQ52539094
HTLV-I associated myelopathy, a new clinical entity.Q55060196
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectvirologyQ7215
leukemiaQ29496
negative regulation of transcription, DNA-templatedQ14633919
Zinc finger protein 282Q21136868
P304page(s)5025-32
P577publication date1997-12-15
P1433published inNucleic Acids ResearchQ135122
P1476titleHUB1, a novel Krüppel type zinc finger protein, represses the human T cell leukemia virus type I long terminal repeat-mediated expression
HUB1, a novel Kruppel type zinc finger protein, represses the human T cell leukemia virus type I long terminal repeat-mediated expression
P478volume25

Reverse relations

cites work (P2860)
Q24292107A novel zinc finger transcription factor with two isoforms that are differentially repressed by estrogen receptor-alpha
Q28207799Bikunin target genes in ovarian cancer cells identified by microarray analysis
Q38663289C2H2 Zinc Finger Proteins: The Largest but Poorly Explored Family of Higher Eukaryotic Transcription Factors
Q92127711DUF3669, a "domain of unknown function" within ZNF746 and ZNF777, oligomerizes and contributes to transcriptional repression
Q37677291Deep vertebrate roots for mammalian zinc finger transcription factor subfamilies
Q38695822Erase-Maintain-Establish: Natural Reprogramming of the Mammalian Epigenome
Q37417663SUMOylation of ZFP282 potentiates its positive effect on estrogen signaling in breast tumorigenesis
Q26782206Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family
Q92558804The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification
Q35068080ZNF282 (Zinc finger protein 282), a novel E2F1 co-activator, promotes esophageal squamous cell carcinoma
Q90108778Zinc-finger protein p52-ZER6 accelerates colorectal cancer cell proliferation and tumour progression through promoting p53 ubiquitination

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