p53 is an important regulator of CCL2 gene expression

scientific article

p53 is an important regulator of CCL2 gene expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2174/156652412802480844
P932PMC publication ID3786129
P698PubMed publication ID22804246

P50authorXiaoren TangQ40174231
P2093author name stringY Yang
M Asano
S Amar
A O'Reilly
A Farquhar
P2860cites workThe conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53Q24297104
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Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2Q28609844
p53: puzzle and paradigmQ29618407
Loss of transforming growth factor-beta signaling in mammary fibroblasts enhances CCL2 secretion to promote mammary tumor progression through macrophage-dependent and -independent mechanismsQ30436152
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Tight DNA binding and oligomerization are dispensable for the ability of p53 to transactivate target genes and suppress transformation.Q34055161
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HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levelsQ34161535
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Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and boneQ37431256
Cell-targeting and cell-penetrating peptides for delivery of therapeutic and imaging agentsQ37668316
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The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulatorQ38306731
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A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritisQ39763545
The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies its functions in cell cycle regulation and apoptosis.Q39806223
Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasisQ39808249
Chemotherapeutic drugs and human tumor cells cytokine networkQ39951513
Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA-damaging agent cisplatin.Q40007507
Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinasesQ40034111
p53 short peptide (p53pep164) regulates lipopolysaccharide-induced tumor necrosis factor-alpha factor/cytokine expressionQ40174140
Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor-kappa B (NF-kappa B).Q40567462
DNA-Protein Interactions in the Proximal ζ-Globin Promoter: Identification of Novel CCACCC- and CCAAT-binding ProteinsQ41030725
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Transcription factor activating protein-2beta: a positive regulator of monocyte chemoattractant protein-1 gene expressionQ42806007
Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript.Q42862265
Induction of monocyte chemoattractant protein-1 (MCP-1/CCL2) gene expression by human immunodeficiency virus-1 Tat in human astrocytes is CDK9 dependentQ43108484
Alternative splicing of p53 and p73: the novel p53 splice variant p53delta is an independent prognostic marker in ovarian cancerQ43184300
Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in ratsQ44183029
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.Q44192183
Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein-1 in cultured human brain-derived progenitor cells.Q44729461
Dual regulation of tumor necrosis factor-alpha-induced CCL2/monocyte chemoattractant protein-1 expression in vascular smooth muscle cells by nuclear factor-kappaB and activator protein-1: modulation by type III phosphodiesterase inhibitionQ44772848
Differential requirement of members of the MAPK family for CCL2 expression by hepatic stellate cells.Q44796898
Sphingosine kinase-1 mediates TNF-alpha-induced MCP-1 gene expression in endothelial cells: upregulation by oscillatory flowQ44932366
CCL2/monocyte chemoattractant protein-1 mediates enhanced transmigration of human immunodeficiency virus (HIV)-infected leukocytes across the blood-brain barrier: a potential mechanism of HIV-CNS invasion and NeuroAIDS.Q45420445
Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapyQ45888903
Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophyQ46092513
Peptides derived from serum amyloid A prevent, and reverse, aortic lipid lesions in apoE-/- miceQ46630363
Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in miceQ47990486
HIV-1 Nef upregulates CCL2/MCP-1 expression in astrocytes in a myristoylation- and calmodulin-dependent manner.Q48394729
MH2 domain of Smad3 reduces HIV-1 Tat-induction of cytokine secretionQ48511851
p53 domains: identification and characterization of two autonomous DNA-binding regionsQ52544476
Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoformQ54382805
p53 is a suppressor of inflammatory response in mice.Q54672229
Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic MiceQ58149069
Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ T lymphocytesQ72717877
Secretion of monocyte chemoattractant protein-1 (MCP-1) by human mononuclear phagocytesQ72759216
Bleomycin sensitivity of mice expressing dominant-negative p53 in the lung epitheliumQ74787837
Regulatory role of p53 in experimental autoimmune encephalomyelitisQ78952331
A distinct p53 protein isoform signature reflects the onset of induction chemotherapy for acute myeloid leukemiaQ79834476
Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gammaQ81111491
Selective CCR2-targeted macrophage depletion ameliorates experimental mesangioproliferative glomerulonephritisQ82759772
The expression of monocyte chemotactic protein-1 in papillary thyroid carcinoma is correlated with lymph node metastasis and tumor recurrenceQ82917048
p53 peptide prevents LITAF-induced TNF-alpha-mediated mouse lung lesions and endotoxic shockQ84334037
P433issue8
P304page(s)929-943
P577publication date2012-09-01
P1433published inCurrent Molecular MedicineQ5195065
P1476titlep53 is an important regulator of CCL2 gene expression
P478volume12

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cites work (P2860)
Q38619367Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling
Q28397726Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis
Q38751550CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma
Q100467652Deficiency of miR-208a Exacerbates CCl4-Induced Acute Liver Injury in Mice by Activating Cell Death Pathways
Q90657242Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis
Q27003079Immune surveillance of unhealthy cells by natural killer cells
Q34482050Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.
Q35133888Oral bacteria and cancer
Q92145315Serological Markers Associated With Response to Immune Checkpoint Blockade in Metastatic Gastrointestinal Tract Cancer
Q88768084TP53 gain-of-function mutation promotes inflammation in glioblastoma
Q33587770The inflammatory cytokine TNFα cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells
Q34531766Total adiponectin, but not inflammatory markers C-reactive protein, tumor necrosis factor-α, interluekin-6 and monocyte chemoattractant protein-1, correlates with increasing glucose intolerance in pregnant Chinese-Americans
Q38930310p53 suppresses CCL2-induced subcutaneous tumor xenograft
Q37194949p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells
Q28394092p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis

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