| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1029420368 |
| P356 | DOI | 10.1007/BF00690212 |
| P698 | PubMed publication ID | 7606822 |
| P50 | author | Alexandru Almasan | Q55313957 |
| P2093 | author name string | G M Wahl | |
| L C Huang | |||
| T G Paulson | |||
| S P Linke | |||
| P2860 | cites work | Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development | Q72718760 |
| Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53 | Q72871721 | ||
| A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle | Q24319785 | ||
| The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 | ||
| DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts | Q24336806 | ||
| UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells | Q24609948 | ||
| WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
| Checkpoints: controls that ensure the order of cell cycle events | Q28131705 | ||
| D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA | Q28183697 | ||
| Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle | Q28189224 | ||
| Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation | Q28249159 | ||
| Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways | Q28253542 | ||
| Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas | Q28255510 | ||
| The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E | Q28257000 | ||
| Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins | Q28257012 | ||
| p21 is a universal inhibitor of cyclin kinases | Q28257305 | ||
| Physical interaction of the retinoblastoma protein with human D cyclins | Q28269103 | ||
| SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene | Q28281071 | ||
| Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation | Q28513619 | ||
| p53-dependent apoptosis modulates the cytotoxicity of anticancer agents | Q29615031 | ||
| Cancer. p53, guardian of the genome | Q29615610 | ||
| Telomere length predicts replicative capacity of human fibroblasts | Q29615745 | ||
| G1 events and regulation of cell proliferation | Q29618317 | ||
| Participation of p53 protein in the cellular response to DNA damage | Q29618319 | ||
| Regulation of retinoblastoma protein functions by ectopic expression of human cyclins | Q29618320 | ||
| The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product | Q29618372 | ||
| E2F: a link between the Rb tumor suppressor protein and viral oncoproteins | Q29618375 | ||
| Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age | Q29618409 | ||
| Mammalian G1 cyclins | Q29618855 | ||
| Functional interactions of the retinoblastoma protein with mammalian D-type cyclins | Q29618856 | ||
| Effects of an Rb mutation in the mouse | Q29619196 | ||
| Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis | Q29619200 | ||
| p53 is required for radiation-induced apoptosis in mouse thymocytes | Q29620281 | ||
| Expression of transcription factor E2F1 induces quiescent cells to enter S phase | Q34354875 | ||
| Cellular targets for transformation by the adenovirus E1A proteins | Q34438094 | ||
| Telomeres, telomerase and senescence | Q34636650 | ||
| p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer. | Q34972350 | ||
| Molecular dissection of mammalian gene amplification: new mechanistic insights revealed by analyses of very early events | Q35317137 | ||
| The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle | Q35379903 | ||
| p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein | Q35433948 | ||
| Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks | Q35652566 | ||
| Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle | Q35677993 | ||
| Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma | Q36228101 | ||
| DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways | Q36647845 | ||
| A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter | Q36676009 | ||
| Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes | Q36686434 | ||
| Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site | Q36717640 | ||
| Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen | Q36774702 | ||
| Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo | Q36795598 | ||
| Overproduction of Rb protein after the G1/S boundary causes G2 arrest | Q36824755 | ||
| Wild-type p53 is a cell cycle checkpoint determinant following irradiation | Q37152060 | ||
| Defining the molecular mechanisms of human cell immortalization | Q37173111 | ||
| DNA amplification is rare in normal human cells | Q37709503 | ||
| Normal diploid human and rodent cells lack a detectable frequency of gene amplification | Q37742113 | ||
| p53 tagged sites from human genomic DNA. | Q38305003 | ||
| The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator | Q38306731 | ||
| The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein | Q38334727 | ||
| The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F | Q38334818 | ||
| Posttranscriptional regulation of thymidylate synthase gene expression | Q40662806 | ||
| Cell cycle targets of the DNA tumor viruses | Q40757521 | ||
| Regulation and mechanisms of mammalian gene amplification. | Q40832217 | ||
| The role of E2F in the mammalian cell cycle | Q40838627 | ||
| The tumor suppressor p53. | Q40838644 | ||
| Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. | Q41436520 | ||
| p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes | Q41454039 | ||
| Identification of a p53-dependent negative response element in the bcl-2 gene | Q41461046 | ||
| Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system | Q41483751 | ||
| Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts | Q41520659 | ||
| Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta. | Q41559119 | ||
| Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runs | Q41572901 | ||
| Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents | Q41575832 | ||
| Cell cycle regulation of gene amplification | Q41586837 | ||
| Cell cycle-specific association of E2F with the p130 E1A-binding protein | Q42804203 | ||
| Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts | Q42807624 | ||
| Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. | Q43918911 | ||
| Requirement for a functional Rb-1 gene in murine development | Q44462954 | ||
| p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. | Q45993768 | ||
| Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen | Q48084448 | ||
| Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. | Q48115514 | ||
| p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens | Q52214399 | ||
| Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins | Q52512094 | ||
| An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120. | Q53514290 | ||
| N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture. | Q53597000 | ||
| Thymocyte apoptosis induced by p53-dependent and independent pathways | Q54242475 | ||
| Adaptive mutation by deletions in small mononucleotide repeats. | Q54630365 | ||
| Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells | Q59057697 | ||
| Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines | Q60200214 | ||
| Association of human cyclin E with a periodic G1-S phase protein kinase | Q67505073 | ||
| Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 | Q67521108 | ||
| Fluorescent methotrexate labeling and flow cytometric analysis of cells containing low levels of dihydrofolate reductase | Q69491670 | ||
| Effects of methotrexate on ribonucleotide pools in growing and in growth-arrested tumor cells and antagonism by RNA synthesis inhibitors | Q70312122 | ||
| Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-L-aspartate, methotrexate, and leucovorin | Q70598422 | ||
| Gamma-irradiation-induced micronuclei from mouse hepatoma cells accumulate high levels of the tumor suppressor protein p53 | Q72065142 | ||
| Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2 | Q72092483 | ||
| p53-dependent apoptosis suppresses tumor growth and progression in vivo | Q72149266 | ||
| Phase I trial of low dose N-phosphonacetyl-L-aspartic acid and high dose 5-fluorouracil administered concomitantly with radiation therapy for unresectable localized adenocarcinoma of the pancreas | Q72178767 | ||
| High levels of p53 protein in UV-irradiated normal human skin | Q72208990 | ||
| WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis | Q72269510 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 59-73 | |
| P577 | publication date | 1995-03-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Cancer and Metastasis Reviews | Q2647982 |
| P1476 | title | Genetic instability as a consequence of inappropriate entry into and progression through S-phase | |
| P478 | volume | 14 |
| Q24538802 | A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapy |
| Q36848850 | A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation |
| Q33807819 | Alternative pathways for the extension of cellular life span: inactivation of p53/pRb and expression of telomerase |
| Q34461120 | Amplification of EMSY, a novel oncogene on 11q13, in high grade ovarian surface epithelial carcinomas |
| Q30305771 | Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks |
| Q74622856 | Cell biology of precancer |
| Q33608768 | Cell cycle control, checkpoint mechanisms, and genotoxic stress |
| Q39806365 | Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle |
| Q40757122 | Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit |
| Q33923955 | Cyclin E induction by genotoxic stress leads to apoptosis of hematopoietic cells |
| Q33762022 | DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint |
| Q34223352 | Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. |
| Q39864354 | Deregulated G1-cyclin expression induces genomic instability by preventing efficient pre-RC formation |
| Q42819037 | Differential effects of novel tumour-derived p53 mutations on the transformation of NIH-3T3 cells |
| Q30866802 | Differential upregulation of p53-responsive genes by genotoxic stress in hematopoietic cells containing wild-type and mutant p53. |
| Q36824489 | E2F4 function in G2: maintaining G2-arrest to prevent mitotic entry with damaged DNA. |
| Q36996106 | E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinoma |
| Q41172182 | Effects of ionizing- and UV B-radiation on proteins controlling cell cycle progression in human cells: comparison of the MCF-7 adenocarcinoma and the SCL-2 squamous cell carcinoma cell line |
| Q36574017 | Elevated Recombination in Immortal Human Cells Is Mediated by HsRAD51 Recombinase |
| Q31859925 | Enzyme-catalyzed therapeutic agent (ECTA) design: activation of the antitumor ECTA compound NB1011 by thymidylate synthase |
| Q41537158 | Epidemiology and molecular biology of Barrett's adenocarcinoma |
| Q40913827 | Flow cytometric evaluation of proliferating cell nuclear antigen expression in human hematopoietic malignancies |
| Q52579916 | Gamma-irradiation stimulates homology-directed DNA double-strand break repair in Drosophila embryo |
| Q33786630 | Gene Amplification in a p53-Deficient Cell Line Requires Cell Cycle Progression under Conditions That Generate DNA Breakage |
| Q41016815 | Genetic Dissection of a Mammalian Replicator in the Human β-Globin Locus |
| Q54541144 | Hepatic cellular senescence pathway genes are induced through histone modifications in a diet-induced obese rat model. |
| Q33181519 | Influence of pentoxifylline, A-802710, propentofylline and A-802715 (Hoechst) on the expression of cell cycle blocks and S-phase content after irradiation damage |
| Q36641723 | Inhibition of radiation-induced apoptosis by dexamethasone in cervical carcinoma cell lines depends upon increased HPV E6/E7. |
| Q33747235 | Molecular and cellular correlates of methotrexate response in childhood acute lymphoblastic leukemia |
| Q36023059 | Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged. |
| Q78462834 | Potential marker of oral squamous cell carcinoma aggressiveness detected by fluorescence in situ hybridization in fine-needle aspiration biopsies |
| Q77333680 | Radiation induced chromosomal instability in human T-lymphocytes |
| Q56902268 | Recombination and its roles in DNA repair, cellular immortalization and cancer |
| Q73593770 | Relation between DNA ploidy status and the expression of the DNA-mismatch repair genes MLH1 and MSH2 in cytological specimens of melanoma lymph node and liver metastases |
| Q41398588 | Resistance to chemotherapeutic antimetabolites: a function of salvage pathway involvement and cellular response to DNA damage |
| Q37778010 | Role of the p53 Family in Stabilizing the Genome and Preventing Polyploidization |
| Q37606164 | Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest |
| Q41710993 | Small-Molecule Inhibitors of Cyclin-Dependent Kinases: Molecular Tools and Potential Therapeutics |
| Q41813747 | The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination |
| Q35191588 | The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer |
| Q40930060 | The role of p53 in regulating genomic stability when DNA and RNA synthesis are inhibited |
| Q35765327 | Tumors associated with p53 germline mutations: a synopsis of 91 families. |
| Q74526892 | pRB, p107 and p130 as transcriptional regulators: Role in cell growth and differentiation |
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