Induction of Sp1 in differentiating human embryonal carcinoma cells triggers transcription of the fibronectin gene

scientific article published on May 1998

Induction of Sp1 in differentiating human embryonal carcinoma cells triggers transcription of the fibronectin gene is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.18.5.3010
P932PMC publication ID110680
P698PubMed publication ID9566920

P2093author name stringK Oda
M Suzuki
T Nakajima
S Sekiya
E Oda
P2860cites workSp3 is a transcriptional activator of the human alpha2(I) collagen geneQ24308687
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expressionQ24337872
Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 geneQ24338257
Cloning and analysis of the promotor region of the human fibronectin geneQ24614047
Dynamic membrane-cytoskeletal interactions: specific association of integrin and talin arises in vivo after phorbol ester treatment of peripheral blood lymphocytesQ24655945
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
High-efficiency transformation of mammalian cells by plasmid DNAQ27860469
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Integrins: a family of cell surface receptorsQ28288125
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domainQ28295806
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cellsQ29547557
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motifQ29620290
Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single geneQ34564573
Fibronectins: multifunctional modular glycoproteinsQ36209364
Molecular cloning and characterization of cellular genes whose expression is repressed by the adenovirus E1a gene products and growth factors in quiescent rat cellsQ36444061
Sp1 binding plays a critical role in Erb-B2- and v-ras-mediated downregulation of alpha2-integrin expression in human mammary epithelial cellsQ36563516
Developmental expression of Sp1 in the mouseQ36688944
Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescenceQ36727404
DNA-DNA subtractive cDNA cloning using oligo(dT)30-Latex and PCR: identification of cellular genes which are overexpressed in senescent human diploid fibroblastsQ36756796
The retinoblastoma gene product regulates Sp1-mediated transcriptionQ36816438
Different activities of the adenovirus types 5 and 12 E1A regions in transformation with the EJ Ha-ras oncogeneQ36867581
The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulatorQ38306731
Induction of E1A-responsive negative factors for transcription of the fibronectin gene in adenovirus E1-transformed rat cellsQ38324841
Serum stimulation of fibronectin gene expression appears to result from rapid serum-induced binding of nuclear proteins to a cAMP response elementQ38341896
Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiationQ38345845
Cell surface receptors for extracellular matrix moleculesQ39160059
Fibronectin and its receptorsQ39488078
The role of fibronectins in embryonic cell migrations.Q39569379
Molecular biology of fibronectinQ39844004
The G1/S boundary-specific enhancer of the rat cdc2 promoterQ40016299
G10BP, an E1A-inducible negative regulator of Sp1, represses transcription of the rat fibronectin geneQ40017282
Nucleotide sequence of a full-length cDNA for mouse cytoskeletal beta-actin mRNA.Q40561043
E1A-responsive elements for repression of rat fibronectin gene transcriptionQ40655173
Sp1-mediated transcriptional activation is repressed by Sp3Q40792899
Fibronectin expression increases during in vitro cellular senescence: correlation with increased cell areaQ41675923
A transient decrease in N-myc expression and its biological role during differentiation of human embryonal carcinoma cellsQ41676167
Expression of various viral and cellular enhancer-promoters during differentiation of human embryonal carcinoma cellsQ41745590
Induction of human embryonal carcinoma cell differentiation using N,N'-hexamethylene bisacetamide in vitroQ41750597
Transcription signals and protein binding sites for sericin gene transcription in vitroQ42073525
Functional analysis of human alpha 1(I) procollagen gene promoter. Differential activity in collagen-producing and -nonproducing cells and response to transforming growth factor beta 1.Q42799594
Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergismQ46405351
An oligodeoxyribonucleotide-directed dual amber method for site-directed mutagenesisQ48075443
Effects of transformation on fibronectin gene expression using cloned fibronectin cDNAQ48410916
Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains.Q52552243
Characterization of a GC-rich Region Containing Sp1 Binding Site(s) as a Constitutive Responsive Element of the α2(I) Collagen Gene in Human FibroblastsQ60537845
Purification and biochemical characterization of the promoter-specific transcription factor, Sp1Q61942294
Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase IIQ64381020
Characterization of human embryonal carcinoma cell lines derived from testicular germ-cell tumorsQ68949895
The capacity for differentiation and production of human chorionic gonadotropin and alpha-fetoprotein in human embryonal carcinoma cell linesQ69055741
Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expressionQ72283120
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectembryonal carcinomaQ1451877
P304page(s)3010-3020
P577publication date1998-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInduction of Sp1 in differentiating human embryonal carcinoma cells triggers transcription of the fibronectin gene
P478volume18

Reverse relations

cites work (P2860)
Q43588639Alteration of nuclear factor-kappaB (NF-kappaB) expression in bone marrow stromal cells treated with etoposide
Q39575631Cloning and characterization of a GC-box binding protein, G10BP-1, responsible for repression of the rat fibronectin gene
Q33858168Cloning of the cyclin A1 genomic structure and characterization of the promoter region. GC boxes are essential for cell cycle-regulated transcription of the cyclin A1 gene.
Q40967490Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1.
Q33805234Human papillomavirus type 16 E7 oncoprotein represses transcription of human fibronectin
Q52064196Identification of an enhancer that controls up-regulation of fibronectin during differentiation of embryonic stem cells into extraembryonic endoderm.
Q44604463Involvement of reactive oxygen species and SP-1 in fibronectin production by oxidized LDL
Q40419035Peroxisome proliferator-activated receptor-gamma ligands suppress fibronectin gene expression in human lung carcinoma cells: involvement of both CRE and Sp1.
Q38348195Progesterone Receptor (hPR) Upregulates the Fibronectin Promoter Activity in Human Decidual Fibroblasts
Q30743258The G10BP-1 gene encoding a GC box binding protein, is a target of Myc and Jun/Fos
Q41993951The leaf extract of Ginkgo Biloba L. suppresses oxidized LDL-stimulated fibronectin production through an antioxidant action in rat mesangial cells
Q40713784The proximal cis-acting elements Sp1, Sp3 and E2F regulate mouse mer gene transcription in Sertoli cells
Q40883612The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251.

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