A novel regulatory element in the dnmt1 gene that responds to co-activation by Rb and c-Jun

scientific article published on 01 May 2001

A novel regulatory element in the dnmt1 gene that responds to co-activation by Rb and c-Jun is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0378-1119(01)00427-9
P698PubMed publication ID11368904

P2093author name stringM Szyf
M Pinard
F D Araujo
A Slack
P2860cites workRole of DNA 5-methylcytosine transferase in cell transformation by fosQ22008665
c-Jun regulates cell cycle progression and apoptosis by distinct mechanismsQ24533507
The retinoblastoma protein and cell cycle controlQ27860722
Targeted mutation of the DNA methyltransferase gene results in embryonic lethalityQ28131773
Recruitment of the retinoblastoma protein to c-Jun enhances transcription activity mediated through the AP-1 binding siteQ28137644
TRANSFAC: an integrated system for gene expression regulationQ29614502
Role for DNA methylation in genomic imprintingQ29618669
Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6Q33630682
AP-1: one switch for many signalsQ33783550
Rb binds c-Jun and activates transcriptionQ33888705
Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotideQ35960841
Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigeneQ36685637
Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathwayQ38299575
The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulatorQ38306731
Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma proteinQ38319003
Differential expression of jun and fos genes during differentiation of mouse P19 embryonal carcinoma cellsQ40517143
Stable expression of antisense Rb-1 RNA inhibits terminal differentiation of mouse myoblast C2 cellsQ41057293
Differentiation induced by RB expression and apoptosis induced by p53 expression in an osteosarcoma cell lineQ41120129
Regulation of DNA methylation by the Ras signaling pathwayQ41345997
Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesisQ41351086
Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domainQ41684439
Mechanism of active transcriptional repression by the retinoblastoma proteinQ42479902
Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structureQ56256578
A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in cultureQ62555340
Nerve growth factor induced differentiation of neuronal cells requires gene methylationQ73113174
Transcriptional regulation of the human DNA Methyltransferase (dnmt1) geneQ73559076
Association of K-ras mutations with p16 methylation in human colon cancerQ77374977
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)87-96
P577publication date2001-05-01
P1433published inGeneQ5531065
P1476titleA novel regulatory element in the dnmt1 gene that responds to co-activation by Rb and c-Jun
P478volume268

Reverse relations

cites work (P2860)
Q33744584DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta
Q36686917Epigenetic targets in GABAergic neurons to treat schizophrenia
Q34984764Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine development.
Q35754455Perinatal α-linolenic acid availability alters the expression of genes related to memory and to epigenetic machinery, and the Mecp2 DNA methylation in the whole brain of mouse offspring
Q34684301RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells.
Q30467200Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons
Q42850721Some facts and thoughts: p73 as a tumor suppressor gene in the network of tumor suppressors
Q42316245c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

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