scholarly article | Q13442814 |
P50 | author | Randall S. Johnson | Q40744820 |
P2093 | author name string | C Moore | |
R Wisdom | |||
P2860 | cites work | FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis | Q24307362 |
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 | ||
Activation of cAMP and mitogen responsive genes relies on a common nuclear factor | Q24313652 | ||
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways | Q24317441 | ||
The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation | Q24318742 | ||
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
Convergence of MAP kinase pathways on the ternary complex factor Sap-1a | Q24532138 | ||
Avian sarcoma virus 17 carries the jun oncogene | Q24611660 | ||
A Restriction Point for Control of Normal Animal Cell Proliferation | Q24620882 | ||
Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2 | Q24642851 | ||
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4 | Q28266936 | ||
Activation of ternary complex factor Elk-1 by stress-activated protein kinases | Q28272395 | ||
Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein | Q28305440 | ||
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB | Q29614706 | ||
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death | Q29614707 | ||
D-type cyclin-dependent kinase activity in mammalian cells | Q29614966 | ||
G1 events and regulation of cell proliferation | Q29618317 | ||
Regulation of transcription by MAP kinase cascades | Q29618477 | ||
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice | Q29618716 | ||
Suppression of TNF-alpha-induced apoptosis by NF-kappaB | Q29618717 | ||
The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death | Q29620021 | ||
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain | Q29620169 | ||
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain | Q29620270 | ||
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product | Q29620421 | ||
Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors | Q30452676 | ||
Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle | Q33319961 | ||
Fos family members induce cell cycle entry by activating cyclin D1. | Q33779543 | ||
Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. | Q34061286 | ||
Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation. | Q35196825 | ||
Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells | Q36552538 | ||
Cellular transformation and malignancy induced by ras require c-jun | Q36561672 | ||
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. | Q36572588 | ||
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control | Q36580820 | ||
Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth | Q36640038 | ||
Rapid and preferential activation of the c-jun gene during the mammalian UV response | Q36693305 | ||
Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity | Q36783092 | ||
12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region | Q36842600 | ||
Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts | Q37257805 | ||
High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1. | Q40023426 | ||
The jun and fos protein families are both required for cell cycle progression in fibroblasts | Q40640263 | ||
CBP-induced stimulation of c-Fos activity is abrogated by E1A. | Q40789535 | ||
Fos is an essential component of the mammalian UV response | Q40789823 | ||
The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light. | Q41078766 | ||
Characterization of the mouse cyclin D3 gene: exon/intron organization and promoter activity | Q41190286 | ||
Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity | Q41593458 | ||
Transformation by FosB requires a trans-activation domain missing in FosB2 that can be substituted by heterologous activation domains | Q41632670 | ||
Inducible regulatory elements in the human cyclin D1 promoter | Q42498965 | ||
Induction of apoptosis by the transcription factor c-Jun | Q42614297 | ||
Functional analysis of a growth factor-responsive transcription factor complex | Q42810320 | ||
Continuous protein synthesis is required to maintain the probability of entry into S phase | Q42831274 | ||
Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha | Q43819767 | ||
Oncogene jun encodes a sequence-specific trans-activator similar to AP-1. | Q46795550 | ||
c-Jun is essential for normal mouse development and hepatogenesis | Q57083732 | ||
Integration of MAP kinase signal transduction pathways at the serum response element | Q58415341 | ||
A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture | Q62555340 | ||
Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element | Q69845699 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | apoptotic process | Q14599311 |
P304 | page(s) | 188-197 | |
P577 | publication date | 1999-01-01 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms | |
P478 | volume | 18 |
Q41901635 | A Systems Biology Approach to Reveal Putative Host-Derived Biomarkers of Periodontitis by Network Topology Characterization of MMP-REDOX/NO and Apoptosis Integrated Pathways |
Q34103743 | A dominant-negative c-jun mutant inhibits lung carcinogenesis in mice |
Q39456231 | A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs |
Q73917968 | A novel regulatory element in the dnmt1 gene that responds to co-activation by Rb and c-Jun |
Q54947398 | A novel role for polymeric immunoglobulin receptor in tumour development: beyond mucosal immunity and into hepatic cancer cell transformation. |
Q38820712 | A p38 Mitogen-Activated Protein Kinase-Regulated Myocyte Enhancer Factor 2-β-Catenin Interaction Enhances Canonical Wnt Signaling |
Q36650302 | AP-1 Is a Key Regulator of Proinflammatory Cytokine TNFα-mediated Triple-negative Breast Cancer Progression. |
Q36301703 | AP-1 and colorectal cancer |
Q29616558 | AP-1 as a regulator of cell life and death |
Q29615217 | AP-1 in cell proliferation and survival |
Q34279346 | AP-1 in mouse development and tumorigenesis |
Q30014831 | AP-1: a double-edged sword in tumorigenesis |
Q39647760 | Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. |
Q40603124 | Accelerated cell cycle progression in osteoblasts overexpressing the c-fos proto-oncogene: induction of cyclin A and enhanced CDK2 activity |
Q39756645 | Accumulation of Fra-1 in ras-transformed cells depends on both transcriptional autoregulation and MEK-dependent posttranslational stabilization |
Q52718358 | Activation of ER Stress-Dependent miR-216b Has a Critical Role in Salviamiltiorrhiza Ethanol-Extract-Induced Apoptosis in U266 and U937 Cells. |
Q44181808 | Activation of stress-activated protein kinases (SAPK) in tendon cells following cyclic strain: the effects of strain frequency, strain magnitude, and cytosolic calcium |
Q33880827 | Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis |
Q36862017 | Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism |
Q38290833 | Adenoviral delivery of A-FOS, an AP-1 dominant negative, selectively inhibits drug resistance in two human cancer cell lines |
Q39546323 | Alternative splicing of SYK regulates mitosis and cell survival |
Q33935135 | Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation |
Q39821441 | Angiotensin II stimulates KLF5 phosphorylation and its interaction with c-Jun leading to suppression of p21 expression in vascular smooth muscle cells |
Q45761983 | Anti-proliferative Effect of C3 Exoenzyme in Fibroblasts is Mediated by c-Jun Phosphorylation. |
Q55484374 | Antioxidant response elements: Discovery, classes, regulation and potential applications. |
Q50047971 | Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells |
Q44203939 | Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK. |
Q38261426 | Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM. |
Q34395580 | Apoptosis regulators and their role in tumorigenesis |
Q90101231 | Association between CD53 genetic polymorphisms and tuberculosis cases |
Q40740556 | Association of long noncoding RNA and c-JUN expression in hepatocellular carcinoma. |
Q33726703 | Attenuated neuroprotective effect of riboflavin under UV-B irradiation via miR-203/c-Jun signaling pathway in vivo and in vitro |
Q36192986 | Auranofin Inhibits Retinal Pigment Epithelium Cell Survival through Reactive Oxygen Species-Dependent Epidermal Growth Factor Receptor/ Mitogen-Activated Protein Kinase Signaling Pathway |
Q33899070 | B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos. |
Q33898297 | BEX2 has a functional interplay with c-Jun/JNK and p65/RelA in breast cancer |
Q79964096 | BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells |
Q23921356 | Benzo(a)pyrene-caused increased G(1)-S transition requires the activation of c-Jun through p53-dependent PI-3K/Akt/ERK pathway in human embryo lung fibroblasts |
Q50067827 | Bioinformatic analysis of gene expression profiling of intracranial aneurysm |
Q38719558 | Bioinformatics analysis of transcription profiling of solid pseudopapillary neoplasm of the pancreas |
Q40099414 | Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1. |
Q43882757 | C-Jun modulates apoptosis but not terminal cell differentiation in murine erythroleukemia cells |
Q38761317 | C3 exoenzyme impairs cell proliferation and apoptosis by altering the activity of transcription factors |
Q57888734 | CBP/p300 Integrates Raf/Rac-Signaling Pathways in the Transcriptional Induction of NF-ATc during T Cell Activation |
Q40303463 | CD40 ligation protects bronchial epithelium against oxidant-induced caspase-independent cell death |
Q43594303 | CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis |
Q36780798 | CSN6 positively regulates c-Jun in a MEKK1-dependent manner |
Q44163246 | Calpain activates caspase-3 during UV-induced neuronal death but only calpain is necessary for death |
Q34668770 | Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression. |
Q28507445 | Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth |
Q33953067 | Cellular senescence and protein degradation: breaking down cancer |
Q39499429 | Characterization of a c-Jun-responsive module in the 5'-flank of the human CYP2J2 gene that regulates transactivation |
Q30596680 | Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system |
Q38379690 | Cis-urocanic acid inhibits SAPK/JNK signaling pathway in UV-B exposed human corneal epithelial cells in vitro |
Q46446224 | Clinical significance of miRNA-autophagy transcript expression in patients with hepatocellular carcinoma. |
Q40608391 | Combined Expression of c-jun, c-fos, and p53 Improves Estimation of Prognosis in Oral Squamous Cell Carcinoma |
Q39459726 | Complex functions of AP-1 transcription factors in differentiation and survival of PC12 cells |
Q92279955 | Compounding effect of vitamin D3 diet, supplementation, and alcohol exposure on macrophage response to mycobacterium infection |
Q36392093 | Concurrent BMP7 and FGF9 signalling governs AP-1 function to promote self-renewal of nephron progenitor cells |
Q58779438 | Constitutive activation and overexpression of NF-κB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis |
Q40127941 | Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway |
Q50335898 | Cooperation between STAT3 and c-jun suppresses Fas transcription. |
Q42804345 | Cooperative DNA binding with AP-1 proteins is required for transformation by EWS-Ets fusion proteins |
Q39565566 | Crosstalk between c-Jun and TAp73alpha/beta contributes to the apoptosis-survival balance |
Q28567264 | Cyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cells |
Q43697238 | Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo. |
Q37505854 | Cyclophosphamide alters the gene expression profile in patients treated with high doses prior to stem cell transplantation. |
Q24303568 | DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth |
Q24811503 | DDT and its metabolites alter gene expression in human uterine cell lines through estrogen receptor-independent mechanisms. |
Q44224221 | Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint |
Q40211903 | Deregulation of AP-1 proteins in collagen gel-induced epithelial cell apoptosis mediated by low substratum rigidity. |
Q92604087 | Development of CAPER peptides for the treatment of triple negative breast cancer |
Q40607333 | Differential phosphorylation of c-Jun and JunD in response to the epidermal growth factor is determined by the structure of MAPK targeting sequences |
Q43980539 | Differential regulation of activator protein 1 activity by glycyrrhizin |
Q34392520 | Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases |
Q24813357 | Discovery of novel biomarkers by microarray analysis of peripheral blood mononuclear cell gene expression in benzene-exposed workers |
Q40560250 | Disruption of MKK4 signaling reveals its tumor-suppressor role in embryonic stem cells |
Q24555198 | Dominant negative c-jun inhibits activation of the cyclin D1 and cyclin E kinase complexes |
Q47967927 | Downregulation of c-Jun expression and cell cycle regulatory molecules in acute myeloid leukemia cells upon CD44 ligation |
Q28205446 | Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells |
Q36222017 | Effects of In Utero Thyroxine Exposure on Murine Cranial Suture Growth |
Q36980048 | Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response. |
Q91636454 | Expression Profile Analysis of the Cell Cycle in Diploid and Tetraploid Carassius auratus red var |
Q40903207 | Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle |
Q34768174 | Expression profiling of genes regulated by Fra-1/AP-1 transcription factor during bleomycin-induced pulmonary fibrosis |
Q54401146 | FGF2 and insulin signaling converge to regulate cyclin D expression in multipotent neural stem cells. |
Q33112702 | Fank1 interacts with Jab1 and regulates cell apoptosis via the AP-1 pathway |
Q39975306 | FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness |
Q58661830 | Functional Interplay Between Nuclear Factor-κB and c-Jun Integrated by Coactivator p300 Determines the Survival of Nerve Growth Factor-Dependent PC12 Cells |
Q54977360 | Functional cooperation between HIF-1α and c-Jun in mediating primary and acquired resistance to gefitinib in NSCLC cells with activating mutation of EGFR. |
Q53289276 | Functional variants of -1318T > G and -673C > T in c-Jun promoter region associated with increased colorectal cancer risk by elevating promoter activity. |
Q36759552 | Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression |
Q35745964 | G Protein-Coupled Receptor and RhoA-Stimulated Transcriptional Responses: Links to Inflammation, Differentiation, and Cell Proliferation |
Q43606335 | Gcn2 mediates Gcn4 activation in response to glucose stimulation or UV radiation not via GCN4 translation |
Q46604217 | Gene profiling in the livers of wild-type and PPARalpha-null mice exposed to perfluorooctanoic acid |
Q38302233 | Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways |
Q91713138 | Gossypol induces apoptosis of multiple myeloma cells through the JUN-JNK pathway |
Q44270136 | Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways |
Q39647641 | Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38 |
Q42248397 | Growth inhibition by the muscarinic M(3) acetylcholine receptor: evidence for p21(Cip1/Waf1) involvement in G(1) arrest. |
Q53604077 | Growth suppression of human mast cells expressing constitutively active c-kit receptors by JNK inhibitor SP600125. |
Q40726746 | H(2)O(2)-induced AP-1 activation and its effect on p21(WAF1/CIP1)-mediated G2/M arrest in a p53-deficient human lung cancer cell |
Q46256621 | HHV-6A/6B Infection of NK Cells Modulates the Expression of miRNAs and Transcription Factors Potentially Associated to Impaired NK Activity |
Q39965289 | Heregulin-beta promotes matrix metalloproteinase-7 expression via HER2-mediated AP-1 activation in MCF-7 cells |
Q36154850 | Human T-cell leukemia virus type 1 (HTLV-1) bZIP factor requires cellular transcription factor JunD to upregulate HTLV-1 antisense transcription from the 3' long terminal repeat |
Q37982050 | Human gene control by vital oncogenes: revisiting a theoretical model and its implications for targeted cancer therapy |
Q37683868 | Hyaluronan-CD44 interaction promotes c-Jun signaling and miRNA21 expression leading to Bcl-2 expression and chemoresistance in breast cancer cells |
Q97681446 | IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma |
Q36260589 | ING5 suppresses proliferation, apoptosis, migration and invasion, and induces autophagy and differentiation of gastric cancer cells: a good marker for carcinogenesis and subsequent progression |
Q24300280 | Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation |
Q39571052 | Identification of genes and transcription factors associated with glucocorticoid response in lens epithelial cells |
Q64082492 | Identification of hub genes in chronically hypoxic myocardium using bioinformatics analysis |
Q35557270 | Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation |
Q91485256 | Image-Based Analysis of Protein Stability |
Q53275845 | Immunohistochemical analysis of c-myc, c-jun and estrogen receptor in normal, hyperplastic and neoplastic endometrium. |
Q38917161 | Impact of polyphenolic components from mulberry on apoptosis of vascular smooth muscle cells |
Q34078580 | Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver |
Q52649597 | In utero exposure to environmentally relevant concentrations of PCB 153 and PCB 118 disrupts fetal testis development in sheep. |
Q36255484 | In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia |
Q44373784 | In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis |
Q35823922 | Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi. |
Q38305422 | Induced JunD in intestinal epithelial cells represses CDK4 transcription through its proximal promoter region following polyamine depletion |
Q53600006 | Induction of transcriptionally active Jun proteins regulates drug-induced senescence. |
Q40102265 | Inhibiting TRAF2-mediated activation of NF-kappaB facilitates induction of AP-1. |
Q40292865 | Inhibition of UVA-induced c-Jun N-terminal kinase activity results in caspase-dependent apoptosis in human keratinocytes |
Q33962291 | Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner |
Q39972513 | Inhibition of myoblast differentiation by tumor necrosis factor alpha is mediated by c-Jun N-terminal kinase 1 and leukemia inhibitory factor |
Q43976028 | Inhibition of urokinase-type plasminogen activator delays expression of c-jun, activated transforming growth factor beta 1, and matrix metalloproteinase 2 during post-hepatectomy liver regeneration in mice |
Q44045947 | Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage |
Q42796003 | Involvement of protein phosphatase 2A nuclear accumulation and subsequent inactivation of activator protein-1 in leptomycin B-inhibited cyclin D1 expression |
Q33887876 | JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system |
Q37694360 | JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species |
Q41895017 | JNK signalling modulates intestinal homeostasis and tumourigenesis in mice |
Q40616440 | JNK-dependent phosphorylation of c-Jun on serine 63 mediates nitric oxide-induced apoptosis of neuroblastoma cells |
Q43124443 | Jun and JunD-dependent functions in cell proliferation and stress response. |
Q24562854 | Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2. |
Q34599920 | Jun is required in Isl1-expressing progenitor cells for cardiovascular development |
Q28589027 | JunB can substitute for Jun in mouse development and cell proliferation |
Q39922891 | JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression |
Q40838867 | JunD protects cells from p53-dependent senescence and apoptosis. |
Q36854925 | JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function |
Q38873324 | KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun |
Q36310772 | Keloids--clinical diagnosis, pathogenesis, and treatment options. |
Q42831719 | Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death |
Q40413322 | Latent membrane protein 1 encoded by Epstein-Barr virus modulates directly and synchronously cyclin D1 and p16 by newly forming a c-Jun/Jun B heterodimer in nasopharyngeal carcinoma cell line |
Q38833050 | Liposarcoma: molecular targets and therapeutic implications |
Q44692605 | Lipoxygenase inhibitors enhance tumor suppressive effects of jun proteins on v-myb-transformed monoblasts BM2. |
Q28569319 | Localization of transcription factor AP-1 family proteins in ameloblast nuclei of the rat incisor |
Q28477996 | Long circulating lectin conjugated paclitaxel loaded magnetic nanoparticles: a new theranostic avenue for leukemia therapy |
Q28566574 | MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress |
Q34102614 | Mammary gland selective excision of c-jun identifies its role in mRNA splicing |
Q91786123 | Matrix Hyaluronan-CD44 Interaction Activates MicroRNA and LncRNA Signaling Associated With Chemoresistance, Invasion, and Tumor Progression |
Q41718515 | Maturational differences in hyperoxic AP-1 activation in rat lung |
Q94093929 | Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC |
Q28505493 | Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects |
Q36323008 | Microarray Analysis of Gene Expression Alteration in Human Middle Ear Epithelial Cells Induced by Asian Sand Dust |
Q34602976 | Molecular mechanism and biological functions of c-Jun N-terminal kinase signalling via the c-Jun transcription factor. |
Q38837139 | Molecular mechanism of anticancer effect of Sclerotium rolfsii lectin in HT29 cells involves differential expression of genes associated with multiple signaling pathways: A microarray analysis |
Q34049359 | Molecular mechanisms of luteolin-7-O-glucoside-induced growth inhibition on human liver cancer cells: G2/M cell cycle arrest and caspase-independent apoptotic signaling pathways |
Q90340155 | Molecular phenotyping using networks, diffusion, and topology: soft tissue sarcoma |
Q33807850 | More than one way to die: apoptosis, necrosis and reactive oxygen damage |
Q30574547 | MuMoD: a Bayesian approach to detect multiple modes of protein-DNA binding from genome-wide ChIP data |
Q24306331 | Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization |
Q35148920 | Network analysis of inflammatory genes and their transcriptional regulators in coronary artery disease |
Q34284148 | Neuronal differentiation and protection from nitric oxide-induced apoptosis require c-Jun-dependent expression of NCAM140. |
Q40560449 | Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs. |
Q28138110 | Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation |
Q36962403 | Overexpression of miR-199a-5p decreases esophageal cancer cell proliferation through repression of mitogen-activated protein kinase kinase kinase-11 (MAP3K11). |
Q35943342 | Oxidant-induced cell death and Nrf2-dependent antioxidative response are controlled by Fra-1/AP-1 |
Q33850204 | Pain and the pathogenesis of biceps tendinopathy |
Q28546967 | Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences |
Q35620896 | Photochemical genotoxicity: principles and test methods. Report of a GUM task force. |
Q39555554 | Pleiotropic action of AP-1 in v-Src-transformed cells |
Q28579449 | Polyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3' untranslated region to HuR and AUF1 |
Q44188955 | Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation |
Q40090069 | Prognostic value from integrative analysis of transcription factors c-Jun and Fra-1 in oral squamous cell carcinoma: a multicenter cohort study |
Q34282536 | Promoter specificity and biological activity of tethered AP-1 dimers |
Q43607743 | Protective role for c-Jun in the cellular response to DNA damage |
Q36952392 | Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury |
Q42812579 | RAS and TGF-beta exert antagonistic effects on extracellular matrix gene expression and fibroblast transformation |
Q38843258 | Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway |
Q75197302 | Ras protects Rb family null fibroblasts from cell death: a role for AP-1 |
Q34973413 | Ras-MAP kinase signaling pathways and control of cell proliferation: relevance to cancer therapy |
Q44324572 | Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide |
Q38293794 | Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling. |
Q34164622 | Regulation of MyoD function in the dividing myoblast |
Q28146223 | Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase |
Q40386886 | Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways. |
Q33944881 | Regulation of gene expression in ovarian cancer cells by luteinizing hormone receptor expression and activation |
Q39080578 | Repeated H2 O2 exposure drives cell cycle progression in an in vitro model of ulcerative colitis |
Q42705907 | Resveratrol stimulates AP-1-regulated gene transcription |
Q43919066 | Retinoic acid inhibits hepatic Jun N-terminal kinase-dependent signaling pathway in ethanol-fed rats |
Q24556611 | Role for the pleckstrin homology domain-containing protein CKIP-1 in AP-1 regulation and apoptosis |
Q40691142 | Role of c-Jun concentration in neuronal cell death |
Q36059868 | Role of oxidative stress in peroxisome proliferator-mediated carcinogenesis |
Q40870782 | Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium |
Q33624528 | SCF/C-Kit/JNK/AP-1 Signaling Pathway Promotes Claudin-3 Expression in Colonic Epithelium and Colorectal Carcinoma |
Q28364720 | SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase |
Q40832473 | Scavenging of extracellular H2O2 by catalase inhibits the proliferation of HER-2/Neu-transformed rat-1 fibroblasts through the induction of a stress response |
Q41471015 | Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth. |
Q42476940 | Selective regulation of c-jun gene expression by mitogen-activated protein kinases via the 12-o-tetradecanoylphorbol-13-acetate- responsive element and myocyte enhancer factor 2 binding sites. |
Q51800786 | Sepsis reveals compartment-specific responses in intestinal proliferation and apoptosis in transgenic mice whose enterocytes re-enter the cell cycle. |
Q42708571 | Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway |
Q35166852 | Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. |
Q30657563 | Skeletal muscle cell activation by low-energy laser irradiation: a role for the MAPK/ERK pathway |
Q37554145 | Spatholobus suberectus Column Extract Inhibits Estrogen Receptor Positive Breast Cancer via Suppressing ER MAPK PI3K/AKT Pathway |
Q42802113 | Src-CrkII-C3G-dependent Activation of Rap1 Switches Growth Hormone-stimulated p44/42 MAP Kinase and JNK/SAPK Activities |
Q36231607 | Stat1-independent regulation of gene expression in response to IFN-gamma |
Q40205386 | Stress-induced c-Jun-dependent Vitamin D receptor (VDR) activation dissects the non-classical VDR pathway from the classical VDR activity |
Q24336620 | Structure and function of human DnaJ homologue subfamily a member 1 (DNAJA1) and its relationship to pancreatic cancer |
Q40171928 | Suppression of keratinocyte stratification by a dominant negative JunB mutant without blocking cell proliferation |
Q33848045 | Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo |
Q38894416 | Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis |
Q24514481 | TIP49b, a regulator of activating transcription factor 2 response to stress and DNA damage |
Q36771972 | TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway |
Q39610319 | TRADD domain of Epstein-Barr virus transforming protein LMP1 is essential for inducing immortalization and suppressing senescence of primary rodent fibroblasts |
Q38916414 | TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor. |
Q35951960 | Targeted deletion of Jun/AP-1 in alveolar epithelial cells causes progressive emphysema and worsens cigarette smoke-induced lung inflammation |
Q38357290 | The -148 to -124 region of c-jun interacts with a positive regulatory factor in rat liver and enhances transcription |
Q31138518 | The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart |
Q61947599 | The AP-1 transcription factor regulates postnatal mammary gland development |
Q36089334 | The EGF receptor is required for efficient liver regeneration |
Q34664167 | The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun |
Q47570670 | The Interplay between Natural Killer Cells and Human Herpesvirus-6. |
Q36111490 | The MAPK signalling pathways and colorectal cancer |
Q41438489 | The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk |
Q35754457 | The UVB-Stimulated Expression of Transglutaminase 1 Is Mediated Predominantly via the NFκB Signaling Pathway: New Evidence of Its Significant Attenuation through the Specific Interruption of the p38/MSK1/NFκBp65 Ser276 Axis |
Q54355360 | The anti-angiogenic activity of rPAI-1(23) inhibits fibroblast growth factor-2 functions. |
Q33825170 | The cancer/testis antigen CAGE with oncogenic potential stimulates cell proliferation by up-regulating cyclins D1 and E in an AP-1- and E2F-dependent manner |
Q58554048 | The close relationship between heparanase and epithelial mesenchymal transition in gastric signet-ring cell adenocarcinoma |
Q34503476 | The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells |
Q77368785 | The expression of genes induced in melanocytes by exposure to 365-nm UVA: study by cDNA arrays and real-time quantitative RT-PCR |
Q38981224 | The interruption of PKC-ι signaling and TRAIL combination therapy against glioblastoma cells |
Q34279339 | The mammalian Jun proteins: redundancy and specificity. |
Q43976249 | The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition |
Q47784628 | The prognostic significance of Jun transcription factors in ovarian cancer |
Q24337110 | The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage |
Q39672712 | The role of signal transducer and activator of transcription 3 in Rift Valley fever virus infection |
Q38069898 | Therapeutic targeting of cancer cell cycle using proteasome inhibitors |
Q90633242 | Transcriptional Regulation of Energy Metabolism in Cancer Cells |
Q42116808 | Transcriptional tools: Small molecules for modulating CBP KIX‐dependent transcriptional activators |
Q38901206 | Transcriptome analysis reveals that Müllerian inhibiting substance regulates signaling pathways that contribute to endometrial carcinogenesis. |
Q52128471 | Transforming growth factor beta (TGFbeta) mediates Schwann cell death in vitro and in vivo: examination of c-Jun activation, interactions with survival signals, and the relationship of TGFbeta-mediated death to Schwann cell differentiation. |
Q40817283 | Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol |
Q40750843 | Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types |
Q35981303 | Trim69 regulates zebrafish brain development by ap-1 pathway |
Q36561559 | Tristetraprolin induces cell cycle arrest in breast tumor cells through targeting AP-1/c-Jun and NF-κB pathway |
Q40127489 | UV Radiation Activates Toll-Like Receptor 9 Expression in Primary Human Keratinocytes, an Event Inhibited by Human Papillomavirus 38 E6 and E7 Oncoproteins |
Q40511411 | UV-induced apoptosis in SH-SY5Y cells: contribution to apoptosis by JNK signaling and cytochrome c. |
Q52348274 | Uncovering the regeneration strategies of zebrafish organs: a comprehensive systems biology study on heart, cerebellum, fin, and retina regeneration. |
Q51752901 | Undernutrition enhances alcohol-induced hepatocyte proliferation in the liver of rats fed via total enteral nutrition. |
Q24672626 | Understanding tendinopathies |
Q33611802 | Up-regulation of SEPT9_v1 stabilizes c-Jun-N-terminal kinase and contributes to its pro-proliferative activity in mammary epithelial cells. |
Q24297063 | Vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun-dependent signaling |
Q58796905 | Virus and tumor microenvironment induced ER stress and unfolded protein response: from complexity to therapeutics |
Q36160009 | Vitamin A depletion induced by cigarette smoke is associated with an increase in lung cancer-related markers in rats |
Q36286873 | WD-repeat protein WDR13 is a novel transcriptional regulator of c-Jun and modulates intestinal homeostasis in mice |
Q43644891 | Widespread transcriptional changes pre-empt the critical pelagic-benthic transition in the vetigastropod Haliotis asinina. |
Q28301962 | Wiring the cell signaling circuitry by the NF-kappa B and JNK1 crosstalk and its applications in human diseases |
Q24617313 | c-JUN prevents methylation of p16(INK4a) (and Cdk6): the villain turned bodyguard |
Q37684175 | c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis |
Q94601787 | c-Jun Overexpression Accelerates Wound Healing in Diabetic Rats by Human Umbilical Cord-Derived Mesenchymal Stem Cells |
Q54960299 | c-Jun Proto-Oncoprotein Plays a Protective Role in Lung Epithelial Cells Exposed to Staphylococcal α-Toxin. |
Q73291709 | c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin |
Q39676079 | c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription. |
Q46540555 | c-Jun controls the efficiency of MAP kinase signaling by transcriptional repression of MAP kinase phosphatases |
Q35691254 | c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis |
Q40274276 | c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation |
Q40283457 | c-Jun promotes cellular survival by suppression of PTEN. |
Q73173837 | c-Jun promotes neurite outgrowth and survival in PC12 cells |
Q40527005 | c-Jun regulates the stability and activity of the p53 homologue, p73. |
Q40027627 | c-Jun supports ribosomal RNA processing and nucleolar localization of RNA helicase DDX21. |
Q40025608 | c-Jun-deficient cells undergo premature senescence as a result of spontaneous DNA damage accumulation. |
Q39450413 | c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents |
Q41621199 | c-Jun-mediated β-1,3-N-acetylglucosaminyltransferase 8 expression: A novel mechanism regulating the invasion and metastasis of colorectal carcinoma cells |
Q36041982 | c-Jun/AP-1 is required for CCK-induced pancreatic acinar cell dedifferentiation and DNA synthesis in vitro. |
Q36325145 | c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation |
Q64104308 | c‑Jun/Ap‑1 is upregulated in an Ang II‑induced abdominal aortic aneurysm formation model and mediates Chop expression in mouse aortic smooth muscle cells |
Q28115960 | eIF3 targets cell-proliferation messenger RNAs for translational activation or repression |
Q28118876 | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation |
Q38924845 | miR-1470 mediates lapatinib induced p27 upregulation by targeting c-jun |
Q36906971 | miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis |
Q42807486 | p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity |
Q33971766 | p75 neurotrophin receptor signaling: mechanisms for neurotrophic modulation of cell stress? |
Q39451919 | v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity. |
Q73322475 | v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release |
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