The interruption of PKC-ι signaling and TRAIL combination therapy against glioblastoma cells

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The interruption of PKC-ι signaling and TRAIL combination therapy against glioblastoma cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1022313339
P356DOI10.1007/S11064-014-1361-8
P698PubMed publication ID24965532
P5875ResearchGate publication ID263431208

P2093author name stringMildred Acevedo-Duncan
Andrea N McCray
Shraddha Desai
P2860cites workc-Jun regulates cell cycle progression and apoptosis by distinct mechanismsQ24533507
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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trialQ29547224
Malignant gliomas in adultsQ29615708
Coordination of glioblastoma cell motility by PKCιQ30496644
Safety and antitumor activity of recombinant soluble Apo2 ligandQ33855449
Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cellsQ33964065
Transduction of tumor necrosis factor-related apoptosis-inducing ligand into hematopoietic cells leads to inhibition of syngeneic tumor growth in vivo.Q34139621
Meta-analysis of oncogenic protein kinase Ciota signaling in lung adenocarcinomaQ35678516
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivoQ36322263
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Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL).Q37221909
A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agentsQ38307538
Regulation of Cdk7 activity through a phosphatidylinositol (3)-kinase/PKC-ι-mediated signaling cascade in glioblastomaQ39453904
A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastomaQ39593833
Protein kinase Ciota is required for pancreatic cancer cell transformed growth and tumorigenesisQ39736038
Involvement of PKC-iota in glioma proliferationQ40022122
Synergistic cytotoxicity through the activation of multiple apoptosis pathways in human glioma cells induced by combined treatment with ionizing radiation and tumor necrosis factor-related apoptosis-inducing ligandQ40157843
Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma.Q40285051
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditionsQ40364656
Atypical protein kinase C iota is an oncogene in human non-small cell lung cancerQ40365768
Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicityQ40402576
Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells.Q40461429
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.Q40975748
Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivoQ41723484
p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cellsQ43561132
Protective role for c-Jun in the cellular response to DNA damageQ43607743
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanineQ48479768
Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomasQ48972634
Cleavage of zetaPKC but not lambda/iotaPKC by caspase-3 during UV-induced apoptosis.Q54100226
Significance and expression of atypical protein kinase C-iota in human hepatocellular carcinoma.Q54501836
Protection of glioblastoma cells from cisplatin cytotoxicity via protein kinase Ciota-mediated attenuation of p38 MAP kinase signaling.Q55470737
Direct stimulation of apoptotic signaling by soluble Apo2l/tumor necrosis factor-related apoptosis-inducing ligand leads to selective killing of glioma cells.Q55474384
Proteolytic activation of protein kinase C delta and epsilon by caspase-3 in U937 cells during chemotherapeutic agent-induced apoptosisQ73316202
Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosisQ77402807
P433issue9
P921main subjectglioblastomaQ282142
P304page(s)1691-1701
P577publication date2014-06-26
P1433published inNeurochemical ResearchQ15716728
P1476titleThe interruption of PKC-ι signaling and TRAIL combination therapy against glioblastoma cells
P478volume39

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cites work (P2860)
Q54977138A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells.
Q38768898PKCα-GSK3β-NF-κB signaling pathway and the possible involvement of TRIM21 in TRAIL-induced apoptosis
Q42117551Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC).

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