| Q38882024 | A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion |
| Q28292920 | Asymmetric cell division of stem and progenitor cells during homeostasis and cancer |
| Q39843379 | Atypical protein kinase C activity is required for extracellular matrix degradation and invasion by Src-transformed cells |
| Q37143104 | Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells |
| Q40402576 | Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity |
| Q38162656 | Atypical protein kinase Cι as a human oncogene and therapeutic target |
| Q57271956 | Aurothiomalate Inhibits Transformed Growth by Targeting the PB1 Domain of Protein Kinase Cι |
| Q36925556 | Cell polarity in development and cancer. |
| Q26853683 | Chemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζ |
| Q54593106 | Coexpression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence. |
| Q41240523 | Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι. |
| Q44553025 | Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι. |
| Q92633600 | Dysfunctional Mechanotransduction through the YAP/TAZ/Hippo Pathway as a Feature of Chronic Disease |
| Q40236633 | Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms |
| Q37866083 | Epithelial cell polarity and tumorigenesis: new perspectives for cancer detection and treatment |
| Q37968480 | Epithelial cell polarity, stem cells and cancer |
| Q38038639 | Epithelial cell polarity: what flies can teach us about cancer. |
| Q101574540 | Equivocal, explicit and emergent actions of PKC isoforms in cancer |
| Q35323930 | Expression of polarity genes in human cancer |
| Q33836807 | Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC). |
| Q36927009 | Genome-wide association study of colorectal cancer in Hispanics |
| Q50700668 | High expression of partitioning defective 3-like protein is associated with malignancy in colorectal cancer. |
| Q34828123 | Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota |
| Q37285084 | Inhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells |
| Q39202768 | Inhibition of atypical protein kinase Cι induces apoptosis through autophagic degradation of β-catenin in esophageal cancer cells |
| Q37121568 | Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1). |
| Q40022122 | Involvement of PKC-iota in glioma proliferation |
| Q93349249 | Knockdown on aPKC-ι inhibits epithelial-mesenchymal transition, migration and invasion of colorectal cancer cells through Rac1-JNK pathway |
| Q37333631 | Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA. |
| Q35678516 | Meta-analysis of oncogenic protein kinase Ciota signaling in lung adenocarcinoma |
| Q35784907 | NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCι/FAK loop |
| Q37588487 | Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex |
| Q30437051 | PKC eta as a therapeutic target in glioblastoma multiforme |
| Q36869444 | PKCiota promotes ovarian tumor progression through deregulation of cyclin E. |
| Q41335368 | PKCζ phosphorylates TRAF2 to protect against intestinal ischemia-reperfusion-induced injury |
| Q58697716 | PKCι and YAP1 are crucial in promoting pancreatic tumorigenesis |
| Q36780352 | PKCι counteracts oxidative stress by regulating Hsc70 in an esophageal cancer cell line |
| Q37466903 | PKCι maintains a tumor-initiating cell phenotype that is required for ovarian tumorigenesis. |
| Q34038395 | PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis |
| Q47154650 | PRKCI promotes immune suppression in ovarian cancer |
| Q37333585 | Par complex in cancer: a regulator of normal cell polarity joins the dark side |
| Q37608855 | Phase I dose escalation study of the PKCι inhibitor aurothiomalate for advanced non-small-cell lung cancer, ovarian cancer, and pancreatic cancer. |
| Q46627896 | Phorbol ester-induced G1 phase arrest selectively mediated by protein kinase Cdelta-dependent induction of p21. |
| Q36881687 | Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis. |
| Q59072618 | Protein Kinase C (PKC) Isozymes and Cancer |
| Q40575136 | Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway |
| Q38171231 | Protein kinase C and cancer: what we know and what we do not. |
| Q37208253 | Protein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progression |
| Q35987724 | Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma. |
| Q35050703 | Protein kinase C iota in the intestinal epithelium protects against dextran sodium sulfate-induced colitis |
| Q28480889 | Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia |
| Q24652905 | Protein kinase C iota: human oncogene, prognostic marker and therapeutic target |
| Q36980701 | Protein kinase C isozymes as therapeutic targets for treatment of human cancers |
| Q34981351 | Protein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanism |
| Q36381266 | Protein kinase Calpha and epsilon small-molecule targeted therapeutics: a new roadmap to two Holy Grails in drug discovery? |
| Q45025054 | Protein kinase CbetaII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo |
| Q39736038 | Protein kinase Ciota is required for pancreatic cancer cell transformed growth and tumorigenesis |
| Q37491175 | Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis. |
| Q34787801 | Protein kinase Cι expression and oncogenic signaling mechanisms in cancer. |
| Q53722723 | Protein kinase Cι is a new prognostic factor in gastric cancer. |
| Q39218553 | RLIP76 is overexpressed in human glioblastomas and is required for proliferation, tumorigenesis and suppression of apoptosis |
| Q37537542 | Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. |
| Q38196268 | Rewiring cell polarity signaling in cancer |
| Q48678789 | Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism |
| Q37673912 | Targeting oncogenic protein kinase Cι for treatment of mutant KRAS LADC. |
| Q37680185 | The aPKCι blocking agent ATM negatively regulates EMT and invasion of hepatocellular carcinoma |
| Q36080446 | The biology and biochemistry of diacylglycerol signalling. Meeting on molecular advances in diacylglycerol signalling |
| Q33699564 | The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness |
| Q37333603 | The epithelial polarity program: machineries involved and their hijacking by cancer. |
| Q37516766 | The high affinity peroxisome proliferator-activated receptor-gamma agonist RS5444 inhibits both initiation and progression of colon tumors in azoxymethane-treated mice |
| Q38981224 | The interruption of PKC-ι signaling and TRAIL combination therapy against glioblastoma cells |
| Q47671913 | Two novel PRKCI polymorphisms and prostate cancer risk in an Eastern Chinese Han population |
| Q37364129 | aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6. |
| Q28252695 | mTOR signaling in tumorigenesis |
| Q36972614 | p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression. |