Coordination of glioblastoma cell motility by PKCι

scientific article

Coordination of glioblastoma cell motility by PKCι is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1051916587
P356DOI10.1186/1476-4598-9-233
P932PMC publication ID2941485
P698PubMed publication ID20815904
P5875ResearchGate publication ID46147267

P50authorDouglas A GrayQ55143473
P2093author name stringDoris A E Parolin
Ian A J Lorimer
Sylvie J Lavictoire
R Mitchell Baldwin
Gordon M Barrett
Jana K Gillies
Judith A Paget
P2860cites workGenetic pathways to glioblastomasQ36094814
The PAR-aPKC system: lessons in polarityQ36416725
Molecular targets of glioma invasion.Q36720990
Aurora-A: the maker and breaker of spindle polesQ36917445
Targeting retrovirus to cancer cells expressing a mutant EGF receptor by insertion of a single chain antibody variable domain in the envelope glycoprotein receptor binding lobeQ38314192
Protein kinase Ciota is required for pancreatic cancer cell transformed growth and tumorigenesisQ39736038
Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma.Q40285051
Atypical protein kinase C iota is an oncogene in human non-small cell lung cancerQ40365768
Protein phosphatase activity of PTEN inhibited the invasion of glioma cells with epidermal growth factor receptor mutation type III expression.Q40403730
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.Q40664929
EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinaseQ41065596
Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.Q42473975
A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.Q44357555
Protein kinase Ciota promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of micro- and m-calpainsQ46856392
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressorsQ47070295
Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas.Q52180037
Protection of glioblastoma cells from cisplatin cytotoxicity via protein kinase Ciota-mediated attenuation of p38 MAP kinase signaling.Q55470737
Myosin IIA regulates cell motility and actomyosin–microtubule crosstalkQ58022519
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42Q22254751
Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancerQ24302626
A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chainQ24307607
Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localizationQ24595932
Protein kinase C iota: human oncogene, prognostic marker and therapeutic targetQ24652905
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1Q28283323
Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzetaQ28583531
Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout miceQ28586326
Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathwaysQ30443468
Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.Q33920769
Regulation of glioblastoma cell invasion by PKC iota and RhoB.Q34739540
P921main subjectglioblastomaQ282142
P304page(s)233
P577publication date2010-09-03
P1433published inMolecular CancerQ15724585
P1476titleCoordination of glioblastoma cell motility by PKCι
P478volume9

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cites work (P2860)
Q35416040Atypical protein kinase C zeta: potential player in cell survival and cell migration of ovarian cancer
Q49478610Failure of the PTEN/aPKC/Lgl Axis Primes Formation of Adult Brain Tumours in Drosophila
Q36954204Identification of key genes in glioblastoma-associated stromal cells using bioinformatics analysis
Q34957420Inhibition of glioblastoma malignancy by Lgl1.
Q38077454PKC signaling in glioblastoma.
Q24297584PKC-ι promotes glioblastoma cell survival by phosphorylating and inhibiting BAD through a phosphatidylinositol 3-kinase pathway
Q38981503PKCι depletion initiates mitotic slippage-induced senescence in glioblastoma
Q37207668PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1.
Q42065297Par6 is phosphorylated by aPKC to facilitate EMT.
Q39562521Proteomics indicates modulation of tubulin polymerization by L-menthol inhibiting human epithelial colorectal adenocarcinoma cell proliferation.
Q39453904Regulation of Cdk7 activity through a phosphatidylinositol (3)-kinase/PKC-ι-mediated signaling cascade in glioblastoma
Q39436597Repression of cancer cell senescence by PKCι.
Q38981224The interruption of PKC-ι signaling and TRAIL combination therapy against glioblastoma cells
Q27316263aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis
Q52593768ω-3 and ω-6 Fatty Acids Modulate Conventional and Atypical Protein Kinase C Activities in a Brain Fatty Acid Binding Protein Dependent Manner in Glioblastoma Multiforme.

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