| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1029199154 |
| P356 | DOI | 10.1038/20466 |
| P698 | PubMed publication ID | 10353252 |
| P2093 | author name string | R P Ricciardi | |
| M E Martin | |||
| A J Berk | |||
| E Lees | |||
| T G Boyer | |||
| P2860 | cites work | E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators | Q64383507 |
| Use of o-phthalaldehyde to reduce background during automated Edman degradation | Q70483021 | ||
| The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1 | Q22001451 | ||
| A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation | Q22008779 | ||
| Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C | Q24311956 | ||
| A Human RNA Polymerase II Complex Containing Factors That Modify Chromatin Structure | Q24522669 | ||
| The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain | Q24609120 | ||
| Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways | Q24681762 | ||
| A kinase-cyclin pair in the RNA polymerase II holoenzyme. | Q27930481 | ||
| Dissecting the regulatory circuitry of a eukaryotic genome | Q28131632 | ||
| NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription | Q28282085 | ||
| Characteristics of a human cell line transformed by DNA from human adenovirus type 5 | Q29547863 | ||
| RNA polymerase II holoenzymes and subcomplexes. | Q34067671 | ||
| Cellular targets for transformation by the adenovirus E1A proteins | Q34438094 | ||
| Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8 | Q34613177 | ||
| trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor | Q36730508 | ||
| Radical mutations reveal TATA-box binding protein surfaces required for activated transcription in vivo. | Q36823841 | ||
| Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome. | Q37412857 | ||
| Adenovirus E1A protein paradigm viral transactivator | Q38261759 | ||
| Growth Suppression by Members of the Retinoblastoma Protein Family | Q40431315 | ||
| Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling | Q41135422 | ||
| RNA polymerase II holoenzyme and transcriptional regulation | Q41477041 | ||
| Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled by | Q44608755 | ||
| sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction | Q48070632 | ||
| Functional interaction of adenovirus E1A with holo-TFIID | Q64377679 | ||
| P433 | issue | 6733 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Adenoviridae | Q193447 |
| P304 | page(s) | 276-9 | |
| P577 | publication date | 1999-05-20 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein | |
| P478 | volume | 399 |
| Q35201961 | A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene |
| Q28217192 | A component of the ARC/Mediator complex required for TGF beta/Nodal signalling |
| Q33203749 | A homologue of Cdk8 is required for spore cell differentiation in Dictyostelium |
| Q30165412 | A lin-45 raf enhancer screen identifies eor-1, eor-2 and unusual alleles of Ras pathway genes in Caenorhabditis elegans |
| Q34083316 | A role for coactivators and histone acetylation in estrogen receptor alpha-mediated transcription initiation |
| Q40671258 | A second pathway for modulating glucocorticoid receptor transactivation properties |
| Q24294905 | A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology |
| Q58994474 | A shared but complex bridge |
| Q22253330 | A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen |
| Q28264676 | A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II |
| Q36347875 | Activation domain–mediator interactions promote transcription preinitiation complex assembly on promoter DNA |
| Q40423684 | Activation of the Notch-regulated transcription factor CBF1/RBP-Jkappa through the 13SE1A oncoprotein |
| Q24540745 | Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation |
| Q41614093 | Activator–Mediator Binding Stabilizes RNA Polymerase II Orientation within the Human Mediator–RNA Polymerase II–TFIIF Assembly |
| Q42508619 | Adenoviral E1A primes alveolar epithelial cells to PM(10)-induced transcription of interleukin-8. |
| Q46231022 | Adenovirus 5 E1A is responsible for increased expression of insulin receptor substrate 4 in established adenovirus 5-transformed cell lines and interacts with IRS components activating the PI3 kinase/Akt signalling pathway |
| Q58693141 | Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting Varied Steps in Transcription at Different Viral Promoters |
| Q39454661 | Adenovirus E1A interacts directly with, and regulates the level of expression of, the immunoproteasome component MECL1 |
| Q34620514 | Adenovirus E1A proteins direct subcellular redistribution of Nek9, a NimA-related kinase |
| Q34468761 | Adenovirus E1A: remodelling the host cell, a life or death experience |
| Q34301861 | Adenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblasts |
| Q36667837 | Adenovirus L-E1A activates transcription through mediator complex-dependent recruitment of the super elongation complex |
| Q30433633 | Adenovirus protein VII condenses DNA, represses transcription, and associates with transcriptional activator E1A. |
| Q35850341 | Adenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival |
| Q44566225 | Akt negatively regulates translation of the ternary complex factor Elk-1. |
| Q33946934 | Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells |
| Q36628205 | Analysis of differential expression of Mediator subunit genes in Arabidopsis |
| Q43786019 | Biological significance of a universally conserved transcription mediator in metazoan developmental signaling pathways |
| Q40124434 | C-terminal-binding protein interacting protein binds directly to adenovirus early region 1A through its N-terminal region and conserved region 3. |
| Q35779330 | C. elegans EOR-1/PLZF and EOR-2 positively regulate Ras and Wnt signaling and function redundantly with LIN-25 and the SUR-2 Mediator component |
| Q34610796 | Caenorhabditis elegans lin-25: a study of its role in multiple cell fate specification events involving Ras and the identification and characterization of evolutionarily conserved domains |
| Q36778835 | Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation |
| Q34614291 | Caenorhabditis elegans unc-37/groucho interacts genetically with components of the transcriptional mediator complex |
| Q38125960 | Canonical RTK-Ras-ERK signaling and related alternative pathways |
| Q57270117 | Cdk1 Triggers Association of RNA Polymerase to Cell Cycle Promoters Only after Recruitment of the Mediator by SBF |
| Q34488124 | Cell proliferation and growth in C. elegans |
| Q42280948 | Cellular GCN5 Is a Novel Regulator of Human Adenovirus E1A-Conserved Region 3 Transactivation |
| Q24550927 | Characterization of mediator complexes from HeLa cell nuclear extract |
| Q64377927 | Chromatin repression by COUP-TFII and HDAC dominates activation by NF-kappaB in regulating major histocompatibility complex class I transcription in adenovirus tumorigenic cells |
| Q36869826 | Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in beta-cells |
| Q42414317 | Coactivator cross-talk specifies transcriptional output |
| Q39753100 | Comparative sequence analysis of the largest E1A proteins of human and simian adenoviruses |
| Q41232401 | Comparison of E1A CR3-Dependent Transcriptional Activation across Six Different Human Adenovirus Subgroups |
| Q40471506 | Comprehensive sequence analysis of the E1A proteins of human and simian adenoviruses. |
| Q34100653 | Cooperative Coactivation of Estrogen Receptor α in ZR-75 Human Breast Cancer Cells by SNURF and TATA-binding Protein |
| Q57842676 | Crystal structure of human Mediator subunit MED23 |
| Q28652765 | Disordered proteinaceous machines |
| Q44934838 | Distinct conformational states of nuclear receptor-bound CRSP-Med complexes |
| Q64249705 | Divergent Evolution of E1A CR3 in Human Adenovirus Species D |
| Q33969120 | Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes |
| Q33967777 | Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters |
| Q35207123 | Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification |
| Q38776838 | Dual role of Med12 in PRC1-dependent gene repression and ncRNA-mediated transcriptional activation. |
| Q38101203 | Dysregulation of the basal RNA polymerase transcription apparatus in cancer |
| Q33737750 | E1A-CR3 interaction-dependent and -independent functions of mSur2 in viral replication of early region 1A mutants of mouse adenovirus type 1. |
| Q42806499 | ERK activation induces phosphorylation of Elk-1 at multiple S/T-P motifs to high stoichiometry |
| Q38696706 | ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain |
| Q21129371 | Elk-1 a transcription factor with multiple facets in the brain |
| Q28216498 | Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man |
| Q36627901 | Evolution of disorder in Mediator complex and its functional relevance |
| Q24538358 | External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivator |
| Q27935993 | Functional connections between mediator components and general transcription factors of Saccharomyces cerevisiae |
| Q40885992 | Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex |
| Q33259344 | Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells |
| Q55260854 | Hacking the Cell: Network Intrusion and Exploitation by Adenovirus E1A. |
| Q39568162 | Herpes Simplex Virus 1 ICP4 Forms Complexes with TFIID and Mediator in Virus-Infected Cells |
| Q42456485 | Heterogeneous nuclear ribonucleoprotein R enhances transcription from the naturally configured c-fos promoter in vitro |
| Q24675260 | Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation |
| Q42829649 | Human cyclin C protein is stabilized by its associated kinase cdk8, independently of its catalytic activity |
| Q35661538 | Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors |
| Q39975279 | Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3. |
| Q52594256 | Identification of a second independent binding site for the pCAF acetyltransferase in adenovirus E1A. |
| Q24535680 | Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator |
| Q39684616 | In vivo association of adenovirus large E1A protein with the human mediator complex in adenovirus-infected and -transformed cells. |
| Q49713290 | Integration of EGFR and LIN-12/Notch Signaling by LIN-1/Elk1, the Cdk8 Kinase Module, and SUR-2/Med23 in Vulval Precursor Cell Fate Patterning in Caenorhabditis elegans |
| Q24670740 | Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response |
| Q37127084 | Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes. |
| Q28589180 | Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action |
| Q24644562 | MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression |
| Q39253483 | Mammalian Mediator 19 Mediates H1299 Lung Adenocarcinoma Cell Clone Conformation, Growth, and Metastasis |
| Q38077643 | Mechanisms of Mediator complex action in transcriptional activation. |
| Q33892757 | Mechanisms of gene regulation by vitamin D(3) receptor: a network of coactivator interactions. |
| Q34348002 | Mediator Complex Dependent Regulation of Cardiac Development and Disease |
| Q36301840 | Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation. |
| Q91721559 | Mediator MED23 regulates inflammatory responses and liver fibrosis |
| Q33909044 | Mediator and human disease |
| Q34463013 | Mediator and p300/CBP-steroid receptor coactivator complexes have distinct roles, but function synergistically, during estrogen receptor alpha-dependent transcription with chromatin templates |
| Q36129156 | Mediator and the mechanism of transcriptional activation |
| Q27930405 | Mediator as a general transcription factor |
| Q34245346 | Mediator complexes and transcription. |
| Q35494027 | Mediator coordinates PIC assembly with recruitment of CHD1 |
| Q52569557 | Mediator is a transducer of Wnt/beta-catenin signaling |
| Q26800203 | Mediator kinase module and human tumorigenesis |
| Q36975019 | Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation |
| Q24304401 | Mediator modulates Gli3-dependent Sonic hedgehog signaling |
| Q22065418 | Mediator of Transcriptional Regulation |
| Q42508865 | Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock |
| Q26995848 | Mediator-dependent nuclear receptor function |
| Q41756522 | Mediator-nucleosome interaction |
| Q37096642 | Message in a nucleus: signaling to the transcriptional machinery |
| Q47549172 | Mimicry of cellular A kinase anchoring proteins is a conserved and critical function of E1A across various human adenovirus species |
| Q41922958 | Modulation of Immune Responses to Herpes Simplex Virus Type 1 by IFNL3 and IRF7 Polymorphisms: A Study in Alzheimer's Disease. |
| Q50335765 | Multimeric Coactivator Complexes for Steroid/Nuclear Receptors |
| Q28567527 | NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC. |
| Q40731209 | Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells |
| Q33757699 | Novel critical role of a human Mediator complex for basal RNA polymerase II transcription |
| Q36478024 | Nuclear receptor coactivator/coregulator NCoA6(NRC) is a pleiotropic coregulator involved in transcription, cell survival, growth and development |
| Q33745092 | Nuclear receptor cofactors as chromatin remodelers |
| Q35805048 | Nuclear receptor-mediated transactivation through interaction with Sp proteins |
| Q26741360 | P-TEFb goes viral |
| Q38896947 | P-TEFb goes viral. |
| Q35802815 | Pharmacology of nuclear receptor-coregulator recognition. |
| Q28215703 | Phosphorylation of the human ubiquitin-conjugating enzyme, CDC34, by casein kinase 2 |
| Q28564353 | Poly(ADP-ribose) polymerase 1 is a key regulator of estrogen receptor α-dependent gene transcription |
| Q24550587 | Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation |
| Q35586902 | Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cells |
| Q35182494 | Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors |
| Q28242122 | Ras induces mediator complex exchange on C/EBP beta |
| Q34469114 | Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus |
| Q44077300 | Regulation of GRIP1 and CBP Coactivator activity by Rho GDI modulates estrogen receptor transcriptional enhancement |
| Q24599178 | Regulation of the 26S proteasome by adenovirus E1A |
| Q58700491 | Regulation of the terminal maturation of iNKT cells by mediator complex subunit 23 |
| Q40275053 | Requirement of Sur2 for efficient replication of mouse adenovirus type 1. |
| Q24537229 | Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s |
| Q33431467 | Requirements for E1A dependent transcription in the yeast Saccharomyces cerevisiae |
| Q33964585 | Robust mRNA transcription in chicken DT40 cells depleted of TAF(II)31 suggests both functional degeneracy and evolutionary divergence |
| Q40598216 | Role of mediator in transcriptional activation by the aryl hydrocarbon receptor |
| Q24554282 | Role of metazoan mediator proteins in interferon-responsive transcription |
| Q24293076 | Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription |
| Q34472506 | Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module |
| Q37073125 | Site-specific Srb10-dependent phosphorylation of the yeast Mediator subunit Med2 regulates gene expression from the 2-microm plasmid |
| Q41370397 | Small molecule probes to target the human Mediator complex |
| Q33813416 | Strategies for transcriptional activation by steroid/nuclear receptors |
| Q35840815 | Structural organization of yeast and mammalian mediator complexes |
| Q27667187 | Structure of the VP16 transactivator target in the Mediator |
| Q27648933 | Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor |
| Q90398112 | Suppression of a Subset of Interferon-Induced Genes by Human Papillomavirus Type 16 E7 via a Cyclin Dependent Kinase 8-Dependent Mechanism |
| Q24674080 | TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA |
| Q28138931 | TFIIH is negatively regulated by cdk8-containing mediator complexes |
| Q24537630 | TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4. |
| Q39458882 | Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1. |
| Q35131700 | Ternary complex factors: prime nuclear targets for mitogen-activated protein kinases |
| Q24682565 | The C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in human nuclear extracts |
| Q44030852 | The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation |
| Q43649651 | The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis |
| Q24554276 | The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes |
| Q33806341 | The E4-6/7 protein functionally compensates for the loss of E1A expression in adenovirus infection |
| Q48874029 | The MED‐7 transcriptional mediator encoded by let‐49 is required for gonad and germ cell development in Caenorhabditis elegans |
| Q28299679 | The Mediator complex and transcription regulation |
| Q37991879 | The Mediator complex in thyroid hormone receptor action |
| Q39175285 | The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members |
| Q38059661 | The RNA Polymerase II Transcriptional Machinery and Its Epigenetic Context |
| Q41996013 | The RNA binding complexes NF45-NF90 and NF45-NF110 associate dynamically with the c-fos gene and function as transcriptional coactivators |
| Q34221274 | The TRAP/SMCC/Mediator complex and thyroid hormone receptor function |
| Q28592968 | The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development |
| Q59350250 | The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species |
| Q22254389 | The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs |
| Q24622776 | The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator |
| Q37145192 | The adenoviral E1B 55-kilodalton protein controls expression of immune response genes but not p53-dependent transcription |
| Q22253389 | The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR |
| Q24291962 | The conserved Mynd domain of BS69 binds cellular and oncoviral proteins through a common PXLXP motif |
| Q37808166 | The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication |
| Q27325648 | The evolutionarily conserved mediator subunit MDT-15/MED15 links protective innate immune responses and xenobiotic detoxification |
| Q28276700 | The human Mediator complex: a versatile, genome-wide regulator of transcription |
| Q44762401 | The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins |
| Q35669882 | The mediator complex |
| Q37799722 | The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation |
| Q34180330 | The nuclear hormone receptor coactivator NRC is a pleiotropic modulator affecting growth, development, apoptosis, reproduction, and wound repair |
| Q40742961 | The viral transactivator E1A regulates the mouse mammary tumor virus promoter in an isoform- and chromatin-specific manner |
| Q28208318 | Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences |
| Q48174606 | Toward understanding of the mechanisms of Mediator function in vivo: Focus on the preinitiation complex assembly |
| Q52899161 | Transactivation of human parvovirus B19 gene expression in endothelial cells by adenoviral helper functions |
| Q24298511 | Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis |
| Q50057687 | Transcription regulation by the Mediator complex |
| Q78198301 | Transcription: Common cofactors and cooperative recruitment |
| Q36053034 | Transcriptional activities of retinoic acid receptors |
| Q39897926 | Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP. |
| Q43002372 | Transcriptional regulation of the human glycoprotein hormone common alpha subunit gene by cAMP-response-element-binding protein (CREB)-binding protein (CBP)/p300 and p53. |
| Q33904338 | Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells |
| Q36994683 | Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation |
| Q35001034 | Walleye dermal sarcoma virus cyclin interacts with components of the mediator complex and the RNA polymerase II holoenzyme |
| Q51040236 | When Ras signaling reaches the mediator |
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