| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Roger D. Kornberg | Q170676 |
| P2860 | cites work | Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro | Q35210134 |
| Structural organization of yeast and mammalian mediator complexes | Q35840815 | ||
| Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock | Q42508865 | ||
| Identification of Rox3 as a component of mediator and RNA polymerase II holoenzyme | Q46042839 | ||
| Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome | Q46391372 | ||
| Dynamics of enhancer-promoter communication during differentiation-induced gene activation | Q49009572 | ||
| Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID | Q59070657 | ||
| Negative effect of the transcriptional activator GAL4 | Q59072863 | ||
| Mechanism of action of an acidic transcriptional activator in vitro | Q70113517 | ||
| Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction | Q74643007 | ||
| Conserved structures of mediator and RNA polymerase II holoenzyme | Q78111811 | ||
| Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex | Q22009519 | ||
| A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology | Q24294905 | ||
| Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex | Q24313231 | ||
| Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s | Q24537229 | ||
| Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation | Q24540745 | ||
| General requirement for RNA polymerase II holoenzymes in vivo | Q24561963 | ||
| A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. | Q27930548 | ||
| Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. | Q27930916 | ||
| A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. | Q27931243 | ||
| The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II. | Q27932964 | ||
| Dissecting the regulatory circuitry of a eukaryotic genome | Q28131632 | ||
| Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein | Q28198008 | ||
| Independent recruitment in vivo by Gal4 of two complexes required for transcription | Q28207045 | ||
| Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man | Q28216498 | ||
| A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II | Q28264676 | ||
| A novel mediator between activator proteins and the RNA polymerase II transcription apparatus | Q28642649 | ||
| Novel critical role of a human Mediator complex for basal RNA polymerase II transcription | Q33757699 | ||
| Yeast GCN4 transcriptional activator protein interacts with RNA polymerase II in vitro | Q33850027 | ||
| A mediator required for activation of RNA polymerase II transcription in vitro | Q34095554 | ||
| P433 | issue | 5 | |
| P1104 | number of pages | 5 | |
| P304 | page(s) | 235-239 | |
| P577 | publication date | 2005-05-01 | |
| P1433 | published in | Trends in Biochemical Sciences | Q1565711 |
| P1476 | title | Mediator and the mechanism of transcriptional activation | |
| P478 | volume | 30 |
| Q35021003 | 1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA |
| Q36603866 | A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism |
| Q41988140 | A TFIIH-associated mediator head is a basal factor of small nuclear spliced leader RNA gene transcription in early-diverged trypanosomes. |
| Q43155322 | A canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome |
| Q42423840 | A chromatin-remodeling protein is a component of fission yeast mediator |
| Q34464746 | A functional portrait of Med7 and the mediator complex in Candida albicans |
| Q40754406 | A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila. |
| Q30415239 | A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31. |
| Q42653651 | A novel link of Mediator with DNA repair |
| Q27650217 | A nuclear receptor-like pathway regulating multidrug resistance in fungi |
| Q36998972 | A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest |
| Q34313461 | A tumour suppressor network relying on the polyamine-hypusine axis |
| Q31166959 | Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair |
| Q27933190 | Activation of a poised RNAPII-dependent promoter requires both SAGA and mediator |
| Q82335657 | Activator-specific recruitment of Mediator in vivo |
| Q59357156 | Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation |
| Q50040433 | Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations |
| Q27678036 | Allosteric Communication in the KIX Domain Proceeds through Dynamic Repacking of the Hydrophobic Core |
| Q42198820 | Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield |
| Q36731615 | An architectural perspective of vitamin D responsiveness. |
| Q28543481 | Analysis of Candida albicans mutants defective in the Cdk8 module of mediator reveal links between metabolism and biofilm formation |
| Q34346604 | Architectural protein subclasses shape 3D organization of genomes during lineage commitment |
| Q40082603 | Architecture of an RNA polymerase II transcription pre-initiation complex |
| Q27670658 | Architecture of the Mediator head module |
| Q24634157 | Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptor-mediated gene transcription and breast cancer cell growth |
| Q41641646 | BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. |
| Q28269301 | BET domain co-regulators in obesity, inflammation and cancer |
| Q38102822 | Baculovirus expression: tackling the complexity challenge. |
| Q34967116 | Beta-catenin hits chromatin: regulation of Wnt target gene activation |
| Q33642463 | Brd2 disruption in mice causes severe obesity without Type 2 diabetes |
| Q57807817 | CDK8 Mediates the Dietary Effects on Developmental Transition in Drosophila |
| Q27347519 | CDK8-Cyclin C Mediates Nutritional Regulation of Developmental Transitions through the Ecdysone Receptor in Drosophila |
| Q34558375 | CDK8: a positive regulator of transcription |
| Q35752537 | CRYPTIC PRECOCIOUS/MED12 is a novel flowering regulator with multiple target steps in Arabidopsis |
| Q44529902 | CYCLIN-DEPENDENT KINASE8 differentially regulates plant immunity to fungal pathogens through kinase-dependent and -independent functions in Arabidopsis |
| Q36109025 | Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice. |
| Q40109457 | Cdk8 is essential for preimplantation mouse development |
| Q90747930 | Chromatin remodeling complexes are involvesd in the regulation of ethanol production during static fermentation in budding yeast |
| Q36104883 | Coactivator MED1 ablation in keratinocytes results in hair-cycling defects and epidermal alterations |
| Q34089711 | Coactivators in PPAR-Regulated Gene Expression |
| Q33359717 | Comparative analysis of the conserved functions of Arabidopsis DRL1 and yeast KTI12. |
| Q36777813 | Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex |
| Q27331366 | Conceptual Model-based Systems Biology: mapping knowledge and discovering gaps in the mRNA transcription cycle |
| Q37374607 | Conditional ablation of mediator subunit MED1 (MED1/PPARBP) gene in mouse liver attenuates glucocorticoid receptor agonist dexamethasone-induced hepatic steatosis |
| Q42055023 | Constitutively-stressed yeast strains are high-yielding for recombinant Fps1: implications for the translational regulation of an aquaporin. |
| Q43179955 | Context-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation |
| Q34416152 | Cooperative binding of transcription factors promotes bimodal gene expression response. |
| Q41598083 | Core Mediator structure at 3.4 Å extends model of transcription initiation complex |
| Q39942822 | Core promoter-selective coregulators of transcription by RNA polymerase II. |
| Q35624739 | Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription |
| Q92487204 | Corynebacterium tuberculostearicum, a human skin colonizer, induces the canonical nuclear factor-κB inflammatory signaling pathway in human skin cells |
| Q33895191 | Cryptococcus neoformans mediator protein Ssn8 negatively regulates diverse physiological processes and is required for virulence |
| Q37379915 | Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites |
| Q33826498 | Cyclin-dependent kinase 8 positively cooperates with Mediator to promote thyroid hormone receptor-dependent transcriptional activation |
| Q36796438 | Cyclins and cell cycle control in cancer and disease |
| Q34253203 | DNA-binding small molecules as inhibitors of transcription factors |
| Q47073976 | Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis |
| Q57814102 | Determinants of selection in yeast evolved by genome shuffling |
| Q33783137 | Differential coregulator requirements for function of the hematopoietic transcription factor GATA-1 at endogenous loci |
| Q28652765 | Disordered proteinaceous machines |
| Q35040985 | Distant positioning of proteasomal proteolysis relative to actively transcribed genes |
| Q34478777 | Distinct regulatory mechanisms of eukaryotic transcriptional activation by SAGA and TFIID |
| Q40204120 | Distinct role of Mediator tail module in regulation of SAGA-dependent, TATA-containing genes in yeast |
| Q35752882 | Distinct roles for Mediator Cdk8 module subunits in Drosophila development. |
| Q39159028 | Downregulation of MED23 promoted the tumorigenecity of esophageal squamous cell carcinoma |
| Q27316136 | Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19 |
| Q37097929 | Dynamic and transient remodeling of the macrophage IL-10 promoter during transcription |
| Q35988268 | Dynamic mechanism for the transcription apparatus orchestrating reliable responses to activators. |
| Q39657214 | Dynamic regulation of histone H3K9 is linked to the switch between replication and transcription at the Dbf4 origin-promoter locus |
| Q38101203 | Dysregulation of the basal RNA polymerase transcription apparatus in cancer |
| Q60907382 | E47 modulates hepatic glucocorticoid action |
| Q35910114 | Emerging Views on the CTD Code |
| Q34498966 | Epigenetic regulation of pluripotency and differentiation |
| Q39301447 | Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer |
| Q36826822 | Establishment of a cell-type-specific genetic network by the mediator complex component Med1. |
| Q35675355 | Facilitated assembly of the preinitiation complex by separated tail and head/middle modules of the mediator |
| Q35004993 | Full and partial genome-wide assembly and disassembly of the yeast transcription machinery in response to heat shock |
| Q29618911 | Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map |
| Q52328152 | Functional diversification accompanies gene family expansion of MED2 homologs in Candida albicans. |
| Q91828974 | Functional interplay between Mediator and RNA polymerase II in Rad2/XPG loading to the chromatin |
| Q28563889 | Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture |
| Q36668486 | Gene expression regulation and cancer |
| Q90337014 | Gene transcription in bursting: a unified mode for realizing accuracy and stochasticity |
| Q37932011 | Gene-specific transcription activation via long-range allosteric shape-shifting |
| Q27939203 | Genetic interactions of MAF1 identify a role for Med20 in transcriptional repression of ribosomal protein genes |
| Q33229782 | Genomewide screen reveals a wide regulatory network for di/tripeptide utilization in Saccharomyces cerevisiae |
| Q46087947 | HISTONE MONOUBIQUITINATION1 interacts with a subunit of the mediator complex and regulates defense against necrotrophic fungal pathogens in Arabidopsis. |
| Q51687001 | HSI2 Repressor Recruits MED13 and HDA6 to Down-Regulate Seed Maturation Gene Expression Directly During Arabidopsis Early Seedling Growth. |
| Q43872500 | Head module control of mediator interactions |
| Q41577510 | Highly organized DnaA-oriC complexes recruit the single-stranded DNA for replication initiation |
| Q38897235 | Homozygous MED25 mutation implicated in eye-intellectual disability syndrome |
| Q37514183 | How eukaryotic genes are transcribed |
| Q39250491 | How many roads lead to cohesinopathies? |
| Q36435346 | Identification of MEDIATOR16 as the Arabidopsis COBRA suppressor MONGOOSE1. |
| Q35748747 | Identification of a regulator of transcription elongation as an accessory factor for the human Mediator coactivator. |
| Q24306298 | Identification of host proteins required for HIV infection through a functional genomic screen |
| Q27653063 | Identification, structure, and functional requirement of the Mediator submodule Med7N/31 |
| Q38951185 | Impact of Pdx1-associated chromatin modifiers on islet β-cells |
| Q26781182 | Importance of Mediator complex in the regulation and integration of diverse signaling pathways in plants |
| Q34563248 | Independent recruitment of mediator and SAGA by the activator Met4 |
| Q34300787 | Infantile cerebral and cerebellar atrophy is associated with a mutation in the MED17 subunit of the transcription preinitiation mediator complex |
| Q36125497 | Influence of Sulfate-Reducing Bacteria on the Corrosion Behavior of High Strength Steel EQ70 under Cathodic Polarization |
| Q34628232 | Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells. |
| Q24670740 | Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response |
| Q28594146 | Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation |
| Q35621184 | Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet |
| Q26995539 | Low-temperature perception leading to gene expression and cold tolerance in higher plants |
| Q34318190 | MC EMiNEM maps the interaction landscape of the Mediator |
| Q24317446 | MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling |
| Q24604899 | MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling |
| Q90345558 | MED12-Related Disease in a Chinese Girl: Clinical Characteristics and Underlying Mechanism |
| Q42508007 | MED12-related XLID disorders are dose-dependent of immediate early genes (IEGs) expression |
| Q24644562 | MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression |
| Q39553019 | MED19 promotes proliferation and tumorigenesis of lung cancer |
| Q90669585 | MED20 is essential for early embryogenesis and regulates NANOG expression |
| Q48932486 | MED23 mutation links intellectual disability to dysregulation of immediate early gene expression |
| Q92643378 | MED25 connects enhancer-promoter looping and MYC2-dependent activation of jasmonate signalling |
| Q35054391 | MED29, a component of the mediator complex, possesses both oncogenic and tumor suppressive characteristics in pancreatic cancer |
| Q35674474 | MED30 Regulates the Proliferation and Motility of Gastric Cancer Cells |
| Q33394559 | Malleable machines in transcription regulation: the mediator complex |
| Q34066027 | Malleable machines take shape in eukaryotic transcriptional regulation |
| Q29618062 | Master transcription factors and mediator establish super-enhancers at key cell identity genes |
| Q38077643 | Mechanisms of Mediator complex action in transcriptional activation. |
| Q37122772 | Mechanisms of antisense transcription initiation from the 3' end of the GAL10 coding sequence in vivo |
| Q38209734 | Med1 subunit of the mediator complex in nuclear receptor-regulated energy metabolism, liver regeneration, and hepatocarcinogenesis |
| Q34938770 | Med25 is required for estrogen receptor alpha (ERα)-mediated regulation of human CYP2C9 expression |
| Q37429800 | Med8, Med18, and Med20 subunits of the Mediator head domain are interdependent upon each other for folding and complex formation |
| Q38713135 | Mediator 1 Is Atherosclerosis Protective by Regulating Macrophage Polarization |
| Q38698214 | Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene |
| Q99557032 | Mediator Subunit MED25 Physically Interacts with PHYTOCHROME INTERACTING FACTOR 4PIF4 to Regulate Shade-induced Hypocotyl Elongation in Tomato |
| Q34220877 | Mediator acts upstream of the transcriptional activator Gal4. |
| Q89180976 | Mediator and RNA polymerase II clusters associate in transcription-dependent condensates |
| Q39239912 | Mediator and SAGA have distinct roles in Pol II preinitiation complex assembly and function |
| Q24632695 | Mediator and cohesin connect gene expression and chromatin architecture |
| Q33909044 | Mediator and human disease |
| Q27930405 | Mediator as a general transcription factor |
| Q27931540 | Mediator complex association with constitutively transcribed genes in yeast |
| Q34348002 | Mediator complex dependent regulation of cardiac development and disease |
| Q35494027 | Mediator coordinates PIC assembly with recruitment of CHD1 |
| Q27667533 | Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization |
| Q40663023 | Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo |
| Q52569557 | Mediator is a transducer of Wnt/beta-catenin signaling. |
| Q24338963 | Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling |
| Q37327569 | Mediator is an intrinsic component of the basal RNA polymerase II machinery in vivo. |
| Q26800203 | Mediator kinase module and human tumorigenesis |
| Q36975019 | Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation |
| Q37388888 | Mediator links transcription and DNA repair by facilitating Rad2/XPG recruitment |
| Q24304401 | Mediator modulates Gli3-dependent Sonic hedgehog signaling |
| Q27936934 | Mediator structural conservation and implications for the regulation mechanism |
| Q41598892 | Mediator structure and rearrangements required for holoenzyme formation. |
| Q50658275 | Mediator subunit 16 functions in the regulation of iron uptake gene expression in Arabidopsis. |
| Q28302854 | Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p |
| Q42653494 | Mediator subunit MED25 links the jasmonate receptor to transcriptionally active chromatin |
| Q28594136 | Mediator subunit MED28 (Magicin) is a repressor of smooth muscle cell differentiation |
| Q55331862 | Mediator subunit MED31 is required for radial patterning of Arabidopsis roots. |
| Q34551948 | Mediator subunit18 controls flowering time and floral organ identity in Arabidopsis |
| Q35867938 | Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells |
| Q43200898 | Mediator subunits and histone methyltransferase Set2 contribute to Ino2-dependent transcriptional activation of phospholipid biosynthesis in the yeast Saccharomyces cerevisiae |
| Q36501700 | Mediator-regulated transcription through the +1 nucleosome |
| Q38854881 | Mediator: A key regulator of plant development |
| Q36990847 | Microarray based analysis of temperature and oxidative stress induced messenger RNA in Schistosoma mansoni |
| Q34697041 | Minireview: estrogen receptor-initiated mechanisms causal to mammalian reproductive behaviors |
| Q42102424 | Model of the Mediator middle module based on protein cross-linking. |
| Q91894104 | Molecular and Phylogenetic Analyses of the Mediator Subunit Genes in Solanum lycopersicum |
| Q34495543 | Molecular architecture of the yeast Mediator complex |
| Q30485683 | MultiBac complexomics |
| Q30445969 | Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance |
| Q42161742 | Mutual remodeling and conformation grid: a mediator code? |
| Q35822220 | New insights into the biogenesis of nuclear RNA polymerases? |
| Q36421112 | Nicotinamide uncouples hormone-dependent chromatin remodeling from transcription complex assembly |
| Q90833266 | Noncanonical CTD kinases regulate RNA polymerase II in a gene-class-specific manner |
| Q42831175 | Nuclear reprogramming: the zygotic transcription program is established through an "erase-and-rebuild" strategy |
| Q90074064 | Nut1/Hos1 and Sas2/Rpd3 control the H3 acetylation of two different sets of osmotic stress-induced genes |
| Q26766397 | On the way of revealing coactivator complexes cross-talk during transcriptional activation |
| Q50026564 | Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of Cyclin C-CDK8/19. |
| Q92966181 | Organization and regulation of gene transcription |
| Q34611184 | Overexpression of LCMR1 is significantly associated with clinical stage in human NSCLC |
| Q35687105 | PAND: A Distribution to Identify Functional Linkage from Networks with Preferential Attachment Property |
| Q92716957 | PPARβ/δ recruits NCOR and regulates transcription reinitiation of ANGPTL4 |
| Q34159503 | PRIC295, a Nuclear Receptor Coactivator, Identified from PPAR-Interacting Cofactor Complex |
| Q34421493 | Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression |
| Q64964623 | Perturbing Enhancer Activity in Cancer Therapy. |
| Q64112291 | Phenotypic and genetic characterization of tomato mutants provides new insights into leaf development and its relationship to agronomic traits |
| Q42764575 | Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators |
| Q35673284 | Phosphorylation of the Gal4 DNA-binding domain is essential for activator mono-ubiquitylation and efficient promoter occupancy. |
| Q38546777 | Plant Mediator complex and its critical functions in transcription regulation |
| Q40843497 | Preparation and topology of the Mediator middle module |
| Q37854594 | Protein-nucleic acid complexes and the role of mass spectrometry in their structure determination |
| Q41472569 | Quantitative analysis of the transcription control mechanism |
| Q27933182 | R-loop mediated transcription-associated recombination in trf4Δ mutants reveals new links between RNA surveillance and genome integrity |
| Q29540749 | RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template |
| Q34960186 | RNA polymerase II transcription elongation control |
| Q34005578 | Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts |
| Q33859341 | Redefining the modular organization of the core Mediator complex |
| Q53612627 | Redox regulation of the MED28 and MED32 mediator subunits is important for development and senescence. |
| Q39439753 | Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif |
| Q36208841 | Regulation of mammalian transcription by Gdown1 through a novel steric crosstalk revealed by cryo-EM |
| Q35266346 | Repressive chromatin affects factor binding at yeast HO (homothallic switching) promoter |
| Q83464912 | Riboactivators: transcription activation by noncoding RNA |
| Q92486491 | Role of integrative structural biology in understanding transcriptional initiation |
| Q60958057 | Role of the pre-initiation complex in Mediator recruitment and dynamics |
| Q54309210 | SAD1, an RNA polymerase I subunit A34.5 of rice, interacts with Mediator and controls various aspects of plant development. |
| Q36421035 | STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation |
| Q96127211 | Selective Mediator dependence of cell-type-specifying transcription |
| Q29617301 | Selective inhibition of tumor oncogenes by disruption of super-enhancers |
| Q36339876 | Selective requirement for Mediator MED23 in Ras-active lung cancer |
| Q42738047 | Selective requirement for SAGA in Hog1-mediated gene expression depending on the severity of the external osmostress conditions |
| Q39923594 | Shields up: the Tup1-Cyc8 repressor complex blocks coactivator recruitment |
| Q49830415 | Silencing SlMED18, tomato Mediator subunit 18 gene, restricts internode elongation and leaf expansion |
| Q64053367 | Smad7:β-catenin complex regulates myogenic gene transcription |
| Q37784071 | Small-molecule regulators that mimic transcription factors |
| Q28513162 | Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1 |
| Q89947701 | Stem rust resistance in wheat is suppressed by a subunit of the mediator complex |
| Q36922952 | Structural flexibility and functional interaction of Mediator Cdk8 module. |
| Q27936384 | Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20. |
| Q27666881 | Structure and VP16 binding of the Mediator Med25 activator interaction domain |
| Q27728022 | Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex |
| Q27674569 | Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II |
| Q27667187 | Structure of the VP16 transactivator target in the Mediator |
| Q27650203 | Structure-system correlation identifies a gene regulatory Mediator submodule |
| Q51769224 | Structures of transcription pre-initiation complex with TFIIH and Mediator. |
| Q24545962 | TFIID and Spt-Ada-Gcn5-acetyltransferase functions probed by genome-wide synthetic genetic array analysis using a Saccharomyces cerevisiae taf9-ts allele |
| Q38803144 | Temporal establishment of neural cell identity in vivo and in vitro |
| Q27929848 | The 19 s proteasome subcomplex establishes a specific protein interaction network at the promoter for stimulated transcriptional initiation in vivo |
| Q42506702 | The 1alpha,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene |
| Q42479323 | The Arabidopsis Mediator Complex Subunit16 Is a Key Component of Basal Resistance against the Necrotrophic Fungal Pathogen Sclerotinia sclerotiorum. |
| Q42437535 | The Arabidopsis Mediator complex subunits MED14/SWP and MED16/SFR6/IEN1 differentially regulate defense gene expression in plant immune responses |
| Q87440912 | The Arabidopsis mediator complex subunit16 positively regulates salicylate-mediated systemic acquired resistance and jasmonate/ethylene-induced defense pathways |
| Q35002822 | The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development. |
| Q50571630 | The Brakeless co-regulator can directly activate and repress transcription in early Drosophila embryos. |
| Q44030852 | The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation |
| Q27938384 | The Ccr4-not complex regulates Skn7 through Srb10 kinase |
| Q33552385 | The MED12-MED13 module of Mediator regulates the timing of embryo patterning in Arabidopsis |
| Q52376071 | The Mediator co-activator complex regulates Ty1 retromobility by controlling the balance between Ty1i and Ty1 promoters. |
| Q28299679 | The Mediator complex and transcription regulation |
| Q51849831 | The Mediator complex in plants: structure, phylogeny, and expression profiling of representative genes in a dicot (Arabidopsis) and a monocot (rice) during reproduction and abiotic stress. |
| Q79853370 | The Pol II initiation complex: finding a place to start |
| Q38977021 | The Structural Basis of Transcription: 10 Years After the Nobel Prize in Chemistry |
| Q37467909 | The basal initiation machinery: beyond the general transcription factors |
| Q33789087 | The eEF1γ subunit contacts RNA polymerase II and binds vimentin promoter region |
| Q42199690 | The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb |
| Q28506353 | The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220 |
| Q37799722 | The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation |
| Q48554301 | The molecular basis of eucaryotic transcription |
| Q24681447 | The molecular basis of eukaryotic transcription |
| Q48328874 | The molecular basis of eukaryotic transcription (Nobel Lecture). |
| Q41182068 | The protein interaction network of the human transcription machinery reveals a role for the conserved GTPase RPAP4/GPN1 and microtubule assembly in nuclear import and biogenesis of RNA polymerase II |
| Q37728861 | The role of Med19 in the proliferation and tumorigenesis of human hepatocellular carcinoma cells |
| Q31034150 | The role of interferon antagonist, non-structural proteins in the pathogenesis and emergence of arboviruses |
| Q28590522 | The role of transcriptional coactivator TRAP220 in myelomonocytic differentiation |
| Q40395489 | The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance |
| Q36362386 | The three clades of the telomere-associated TLO gene family of Candida albicans have different splicing, localization, and expression features |
| Q41986278 | The transcriptional coactivator DRIP/mediator complex is involved in vitamin D receptor function and regulates keratinocyte proliferation and differentiation |
| Q34178119 | The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression |
| Q50648115 | The transcriptional repressor ARR1-SRDX suppresses pleiotropic cytokinin activities in Arabidopsis. |
| Q36332065 | The vitamin D3 transcriptomic response in skin cells derived from the Atlantic bottlenose dolphin. |
| Q28312198 | The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney |
| Q37534207 | Tissue specific expression profile of Mediator genes in Arabidopsis |
| Q55193792 | Titer estimation for quality control (TEQC) method: A practical approach for optimal production of protein complexes using the baculovirus expression vector system. |
| Q94564366 | Transcription and Translation Inhibitors in Cancer Treatment |
| Q33615338 | Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse. |
| Q37603622 | Transcription dynamics |
| Q36162657 | Transcription initiation by human RNA polymerase II visualized at single-molecule resolution |
| Q35879126 | Transcription reactivation steps stimulated by oocyte maturation in C. elegans |
| Q50057687 | Transcription regulation by the Mediator complex |
| Q34137394 | Transcriptional Enhancers in Animal Development and Evolution |
| Q84803397 | Transcriptional activation requires protection of the TATA-binding protein Tbp1 by the ubiquitin-specific protease Ubp3 |
| Q36661884 | Transcriptional control of cell-cycle quiescence during C. elegans development |
| Q34700755 | Transcriptional control of erythropoiesis: emerging mechanisms and principles. |
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| Q34036033 | Transcriptional regulation and its misregulation in disease. |
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| Q34963539 | Transient-state kinetic analysis of transcriptional activator·DNA complexes interacting with a key coactivator |
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| Q36691874 | Type I interferon inhibits varicella-zoster virus replication by interfering with the dynamic interaction between mediator and IE62 within replication compartments. |
| Q90103124 | Understanding Obesity as a Risk Factor for Uterine Tumors Using Drosophila |
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| Q33698048 | Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity. |
| Q92472990 | Variants in MED12L, encoding a subunit of the mediator kinase module, are responsible for intellectual disability associated with transcriptional defect |
| Q36994683 | Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation |
| Q39746292 | Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation |
| Q33426329 | Where does mediator bind in vivo? |
| Q28475915 | Yeast biological networks unfold the interplay of antioxidants, genome and phenotype, and reveal a novel regulator of the oxidative stress response |
| Q34034550 | Yin and yang of mediator function revealed by human mutants |
| Q33327592 | Zebrafish brd2a and brd2b are paralogous members of the bromodomain-ET (BET) family of transcriptional coregulators that show structural and expression divergence |
| Q37263272 | eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts. |
| Q41824511 | p53 activates transcription by directing structural shifts in Mediator |
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