| scholarly article | Q13442814 |
| P2093 | author name string | Y J Kim | |
| Y Li | |||
| R D Kornberg | |||
| M H Sayre | |||
| S Björklund | |||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Srb2p YHR041C | Q27547404 |
| Gal11p YOL051W | Q27548142 | ||
| TATA-binding protein-associated factor TAF14 YPL129W | Q27549571 | ||
| Srb4p YER022W | Q27549886 | ||
| Srb6p YBR253W | Q27550253 | ||
| Srb5p YGR104C | Q27551249 | ||
| P304 | page(s) | 599-608 | |
| P577 | publication date | 1994-05-20 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. | |
| P478 | volume | 77 |
| Q30458326 | 2ab assembly: a methodology for automatable, high-throughput assembly of standard biological parts |
| Q92797791 | 50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms |
| Q33368388 | A CTD function linking transcription to splicing |
| Q54976735 | A Cotton Cyclin-Dependent Kinase E Confers Resistance to Verticillium dahliae Mediated by Jasmonate-Responsive Pathway. |
| Q38318032 | A DEAD box RNA helicase is critical for pre-mRNA splicing, cold-responsive gene regulation, and cold tolerance in Arabidopsis. |
| Q34687021 | A Mediator-responsive form of metazoan RNA polymerase II. |
| Q33651485 | A TATA-binding protein mutant defective for TFIID complex formation in vivo |
| Q42423840 | A chromatin-remodeling protein is a component of fission yeast mediator |
| Q36556030 | A class of activation domains interacts directly with TFIIA and stimulates TFIIA-TFIID-promoter complex assembly |
| Q27936721 | A co-activator of nitrogen-regulated transcription in Saccharomyces cerevisiae |
| Q24323095 | A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily |
| Q45264869 | A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer |
| Q74016365 | A debilitating mutation in transcription factor IIE with differential effects on gene expression in yeast |
| Q34464746 | A functional portrait of Med7 and the mediator complex in Candida albicans |
| Q27936324 | A high resolution protein interaction map of the yeast Mediator complex |
| Q27933520 | A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein. |
| Q27939183 | A highly conserved domain of RNA polymerase II shares a functional element with acidic activation domains of upstream transcription factors |
| Q28276653 | A human RNA polymerase II complex associated with SRB and DNA-repair proteins |
| Q24522669 | A human RNA polymerase II complex containing factors that modify chromatin structure |
| Q40185076 | A kinase subunit of the human mediator complex, CDK8, positively regulates transcriptional activation |
| Q27930481 | A kinase-cyclin pair in the RNA polymerase II holoenzyme. |
| Q34295542 | A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription |
| Q24322024 | A mammalian SRB protein associated with an RNA polymerase II holoenzyme |
| Q24324110 | A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains |
| Q27936438 | A motif shared by TFIIF and TFIIB mediates their interaction with the RNA polymerase II carboxy-terminal domain phosphatase Fcp1p in Saccharomyces cerevisiae |
| Q52590336 | A mouse in vitro transcription system reconstituted from highly purified RNA polymerase II, TFIIH and recombinant TBP, TFIIB, TFIIE and TFIIF. |
| Q39722071 | A multiplicity of mediators: alternative forms of transcription complexes communicate with transcriptional regulators |
| Q36561614 | A new class of activation-defective TATA-binding protein mutants: evidence for two steps of transcriptional activation in vivo |
| Q22011164 | A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth |
| Q22008779 | A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation |
| Q27931700 | A novel yeast protein influencing the response of RNA polymerase II to transcriptional activators |
| Q27938054 | A protein interaction map of the mitotic spindle |
| Q35171792 | A regulatory shortcut between the Snf1 protein kinase and RNA polymerase II holoenzyme |
| Q35154714 | A role of transcriptional activators as antirepressors for the autoinhibitory activity of TATA box binding of transcription factor IID. |
| Q36565816 | A severely defective TATA-binding protein-TFIIB interaction does not preclude transcriptional activation in vivo |
| Q38315368 | A single point mutation in TFIIA suppresses NC2 requirement in vivo |
| Q24530656 | A target essential for the activity of a nonacidic yeast transcriptional activator |
| Q30829987 | A testis-specific transcription factor IIA (TFIIAtau) stimulates TATA-binding protein-DNA binding and transcription activation |
| Q40018556 | A three-step pathway of transcription initiation leading to promoter clearance at an activation RNA polymerase II promoter |
| Q59071495 | A transcription reinitiation intermediate that is stabilized by activator |
| Q24645448 | A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans |
| Q27938961 | A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p |
| Q36382709 | A truncated form of the Pho80 cyclin redirects the Pho85 kinase to disrupt vacuole inheritance in S. cerevisiae |
| Q28264676 | A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II |
| Q42519847 | A yeast transcriptional stimulatory protein similar to human PC4. |
| Q27932447 | ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription |
| Q73521390 | ATPase and ubiquitin-binding proteins of the yeast proteasome |
| Q40445630 | Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast |
| Q37297562 | Activation domain-mediated enhancement of activator binding to chromatin in mammalian cells |
| Q36347875 | Activation domain–mediator interactions promote transcription preinitiation complex assembly on promoter DNA |
| Q36239308 | Activation of RNA polymerase II by topologically linked DNA-tracking proteins |
| Q27933190 | Activation of a poised RNAPII-dependent promoter requires both SAGA and mediator |
| Q54567789 | Activation of prokaryotic transcription through arbitrary protein-protein contacts. |
| Q47858055 | Activation of transcription in vitro by recruitment of the yeast RNA polymerase II holoenzyme |
| Q24646051 | Activator Gcn4 employs multiple segments of Med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo |
| Q24540745 | Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation |
| Q27933836 | Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation |
| Q38297759 | Additive activation of yeast LEU4 transcription by multiple cis elements |
| Q73248351 | Affinity purification of a human RNA polymerase II complex using monoclonal antibodies against transcription factor IIF |
| Q28572297 | Affinity purification of mammalian RNA polymerase I. Identification of an associated kinase |
| Q24530608 | An RNA polymerase II complex containing all essential initiation factors binds to the activation domain of PAR leucine zipper transcription factor thyroid embryonic factor |
| Q39445291 | An activator binding module of yeast RNA polymerase II holoenzyme |
| Q27938223 | An activator target in the RNA polymerase II holoenzyme |
| Q27932320 | An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p |
| Q48542725 | An autobiographic conversation with Roger D. Kornberg on his work on transcription regulation |
| Q34926379 | An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components |
| Q24649275 | An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae |
| Q37258622 | An initiation element in the yeast CUP1 promoter is recognized by RNA polymerase II in the absence of TATA box-binding protein if the DNA is negatively supercoiled |
| Q78101732 | An interaction between the N-terminal region and the core domain of yeast TFIIB promotes the formation of TATA-binding protein-TFIIB-DNA complexes |
| Q39723957 | An in vivo requirement for the mediator subunit med14 in the maintenance of stem cell populations |
| Q73094158 | Analysis by atomic force microscopy of Med8 binding to cis-acting regulatory elements of the SUC2 and HXK2 genes of saccharomyces cerevisiae |
| Q33946934 | Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells |
| Q36628205 | Analysis of differential expression of Mediator subunit genes in Arabidopsis |
| Q80953636 | Another piece in the transcription initiation puzzle |
| Q34418425 | Archaeal proteasomes: proteolytic nanocompartments of the cell |
| Q40082603 | Architecture of an RNA polymerase II transcription pre-initiation complex |
| Q27670658 | Architecture of the Mediator head module |
| Q27929743 | Artificial recruitment of certain Mediator components affects requirement of basal transcription factor IIE. |
| Q28236002 | Association of Cdk-activating kinase subunits with transcription factor TFIIH |
| Q28304889 | Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes |
| Q24537648 | Association of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzyme |
| Q33713593 | Association of the Mediator complex with enhancers of active genes |
| Q40736935 | Autonomous function of the amino-terminal inhibitory domain of TAF1 in transcriptional regulation |
| Q24675704 | BRCA1 is a component of the RNA polymerase II holoenzyme |
| Q38102822 | Baculovirus expression: tackling the complexity challenge. |
| Q42484764 | Basal promoter elements as a selective determinant of transcriptional activator function |
| Q29614681 | Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme |
| Q24609153 | Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53 |
| Q33635743 | Biochemistry meets genetics in the holoenzyme |
| Q74380467 | Broad requirement for the mediator subunit RGR-1 for transcription in the Caenorhabditis elegans embryo |
| Q34094495 | CDK8 is a positive regulator of transcriptional elongation within the serum response network |
| Q36778835 | Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation |
| Q27935522 | Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme |
| Q57270117 | Cdk1 Triggers Association of RNA Polymerase to Cell Cycle Promoters Only after Recruitment of the Mediator by SBF |
| Q46348787 | Characterization of Mediator Complex and its Associated Proteins from Rice |
| Q58130306 | Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding Protein |
| Q24550927 | Characterization of mediator complexes from HeLa cell nuclear extract |
| Q27939719 | Characterization of the Wtm proteins, a novel family of Saccharomyces cerevisiae transcriptional modulators with roles in meiotic regulation and silencing |
| Q27930708 | Characterization of the basal inhibitor of class II transcription NC2 from Saccharomyces cerevisiae |
| Q34601114 | Characterization of the interaction between the acidic activation domain of VP16 and the RNA polymerase II initiation factor TFIIB |
| Q42444028 | Chicken vigilin gene: a distinctive pattern of hypersensitive sites is characteristic for its transcriptional activity. |
| Q40948234 | Chromatin structure and RNA polymerase II connection: implications for transcription |
| Q27937428 | Cloning and characterization of an essential Saccharomyces cerevisiae gene, TAF40, which encodes yTAFII40, an RNA polymerase II-specific TATA-binding protein-associated factor |
| Q24320216 | Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila |
| Q42414317 | Coactivator cross-talk specifies transcriptional output |
| Q38331939 | Cohesin regulates MHC class II genes through interactions with MHC class II insulators |
| Q34411110 | Comparative amino acid sequence analysis of the C6 zinc cluster family of transcriptional regulators. |
| Q36777813 | Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex |
| Q22009528 | Composite co-activator ARC mediates chromatin-directed transcriptional activation |
| Q78111811 | Conserved structures of mediator and RNA polymerase II holoenzyme |
| Q40970406 | Contacts in context: promoter specificity and macromolecular interactions in transcription |
| Q28482259 | Context-dependent dual role of SKI8 homologs in mRNA synthesis and turnover |
| Q41956978 | Continuous and widespread roles for the Swi-Snf complex in transcription |
| Q40999474 | Control of transcription by steroid hormones |
| Q35192625 | Conversion of the omega subunit of Escherichia coli RNA polymerase into a transcriptional activator or an activation target |
| Q38621652 | Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3. |
| Q71841189 | Core promoter elements are essential as selective determinants for function of the yeast transcription factor GAL11 |
| Q35624739 | Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription |
| Q39445508 | Corepressor required for adenovirus E1B 55,000-molecular-weight protein repression of basal transcription |
| Q42435364 | Critical role of the second stirrup region of the TATA-binding protein for transcriptional activation both in yeast and human |
| Q38870319 | Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein α. |
| Q74263600 | Cyclin-dependent kinase inhibitor p16INK4A inhibits phosphorylation of RNA polymerase II by general transcription factor TFIIH |
| Q27939285 | Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast |
| Q60073666 | Cyclins in initiation |
| Q39575245 | DA-complex assembly activity required for VP16C transcriptional activation |
| Q43749179 | DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates |
| Q33708432 | Defining mechanisms that regulate RNA polymerase II transcription in vivo |
| Q47073976 | Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis |
| Q33886575 | Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation |
| Q28776386 | Different upstream transcriptional activators have distinct coactivator requirements |
| Q24563324 | Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1 |
| Q27930411 | Direct interaction of RNA polymerase II and mediator required for transcription in vivo. |
| Q28115255 | Direct interaction of TFIIB and the IE protein of equine herpesvirus 1 is required for maximal trans-activation function |
| Q42483408 | Direct modulation of RNA polymerase core functions by basal transcription factors. |
| Q28131632 | Dissecting the regulatory circuitry of a eukaryotic genome |
| Q34179615 | Dissection of transcription factor TFIIF functional domains required for initiation and elongation |
| Q27939905 | Dissociable Rpb4-Rpb7 subassembly of rna polymerase II binds to single-strand nucleic acid and mediates a post-recruitment step in transcription initiation. |
| Q41076983 | Distinct activated and non-activated RNA polymerase II complexes in yeast |
| Q28209264 | Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme |
| Q37380380 | Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. |
| Q33969120 | Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes |
| Q33967777 | Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters |
| Q38101203 | Dysregulation of the basal RNA polymerase transcription apparatus in cancer |
| Q34816568 | Elongation by RNA polymerase II: structure-function relationship |
| Q58318826 | Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation |
| Q48121126 | Emerging functions of multi-protein complex Mediator with special emphasis on plants |
| Q34520505 | Emerging roles of the 26S proteasome in nuclear hormone receptor-regulated transcription. |
| Q59098614 | Enhancement of TBP binding by activators and general transcription factors |
| Q33361712 | Epigenomics and bolting tolerance in sugar beet genotypes |
| Q37697966 | Escherichia coli FtsH is a membrane-bound, ATP-dependent protease which degrades the heat-shock transcription factor sigma 32. |
| Q33970848 | Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes |
| Q56097506 | Essential role of MED1 in the transcriptional regulation of ER-dependent oncogenic miRNAs in breast cancer |
| Q28140995 | Estrogen receptor interaction with co-activators and co-repressors |
| Q29616537 | Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter |
| Q41708885 | Eukaryotic transcription: an interlaced network of transcription factors and chromatin-modifying machines |
| Q33803995 | Eukaryotic transcriptional control |
| Q36178456 | Evidence for a mediator cycle at the initiation of transcription. |
| Q28216498 | Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man |
| Q36078777 | Evidence of the involvement of O-GlcNAc-modified human RNA polymerase II CTD in transcription in vitro and in vivo |
| Q41138301 | Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo |
| Q30700508 | Evidence that TAF-TATA box-binding protein interactions are required for activated transcription in mammalian cells |
| Q33968949 | Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae. |
| Q41376198 | Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability |
| Q27936096 | Evidence that transcription factor IIB is required for a post-assembly step in transcription initiation |
| Q36627901 | Evolution of disorder in Mediator complex and its functional relevance |
| Q34027969 | Evolution of the RNA polymerase II C-terminal domain |
| Q27934996 | Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo |
| Q36623298 | Extensive purification of a putative RNA polymerase I holoenzyme from plants that accurately initiates rRNA gene transcription in vitro |
| Q22003918 | FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO |
| Q35675355 | Facilitated assembly of the preinitiation complex by separated tail and head/middle modules of the mediator |
| Q24546284 | Factors associated with the mammalian RNA polymerase II holoenzyme |
| Q27938015 | Fcp1 directly recognizes the C-terminal domain (CTD) and interacts with a site on RNA polymerase II distinct from the CTD. |
| Q27937030 | Fluorescence-based analyses of the effects of full-length recombinant TAF130p on the interaction of TATA box-binding protein with TATA box DNA. |
| Q24649809 | Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF |
| Q34904976 | Function and regulation of the Mediator complex |
| Q58696257 | Functional analysis of the Ume3p/ Srb11p-RNA polymerase II holoenzyme interaction |
| Q52668783 | Functional and physical interactions within the middle domain of the yeast mediator. |
| Q27939623 | Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo |
| Q27935993 | Functional connections between mediator components and general transcription factors of Saccharomyces cerevisiae |
| Q36421299 | Functional conservation of the glutamine-rich domains of yeast Gal11 and human SRC-1 in the transactivation of glucocorticoid receptor Tau 1 in Saccharomyces cerevisiae |
| Q42453747 | Functional correlation among Gal11, transcription factor (TF) IIE, and TFIIH in Saccharomyces cerevisiae. Gal11 and TFIIE cooperatively enhance TFIIH-mediated phosphorylation of RNA polymerase II carboxyl-terminal domain sequences |
| Q33202199 | Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria. |
| Q34602774 | Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae |
| Q27935484 | Functional interactions within yeast mediator and evidence of differential subunit modifications |
| Q28563889 | Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture |
| Q36412489 | Functional metabolomics as a tool to analyze Mediator function and structure in plants |
| Q39574441 | Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional corepressor Ssn6-Tup1. |
| Q24533173 | Functional studies of the carboxy-terminal repeat domain of Drosophila RNA polymerase II in vivo |
| Q31133536 | Functional studies of the yeast med5, med15 and med16 mediator tail subunits. |
| Q34309986 | GAL4 interacts with TATA-binding protein and coactivators |
| Q33968670 | GCN5 dependence of chromatin remodeling and transcriptional activation by the GAL4 and VP16 activation domains in budding yeast |
| Q52849456 | Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription. |
| Q24561963 | General requirement for RNA polymerase II holoenzymes in vivo |
| Q27933805 | Genetic analysis of the YDR1-BUR6 repressor complex reveals an intricate balance among transcriptional regulatory proteins in yeast |
| Q52511808 | Genetic evidence for the interaction of the yeast transcriptional co-activator proteins GCN5 and ADA2. |
| Q34644123 | Genetic interactions of DST1 in Saccharomyces cerevisiae suggest a role of TFIIS in the initiation-elongation transition |
| Q34310604 | Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain |
| Q40056449 | Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae. |
| Q74670392 | Global transcription regulators of eukaryotes |
| Q40015882 | HPR1 encodes a global positive regulator of transcription in Saccharomyces cerevisiae |
| Q43872500 | Head module control of mediator interactions |
| Q39631335 | Heat shock factor increases the reinitiation rate from potentiated chromatin templates. |
| Q45764450 | Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5. |
| Q39568162 | Herpes simplex virus 1 ICP4 forms complexes with TFIID and mediator in virus-infected cells |
| Q33812313 | Herpes simplex virus type 1 ICP4 promotes transcription preinitiation complex formation by enhancing the binding of TFIID to DNA |
| Q42456485 | Heterogeneous nuclear ribonucleoprotein R enhances transcription from the naturally configured c-fos promoter in vitro |
| Q90631479 | High-resolution cryo-EM structures of TFIIH and their functional implications |
| Q33886079 | Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. |
| Q24647364 | Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation |
| Q33957262 | Histone acetyltransferase and protein kinase activities copurify with a putative Xenopus RNA polymerase I holoenzyme self-sufficient for promoter-dependent transcription |
| Q77652527 | Histone-like TAFs are essential for transcription in vivo |
| Q37514183 | How eukaryotic genes are transcribed |
| Q35075758 | How the ubiquitin-proteasome system controls transcription |
| Q27934566 | Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme. |
| Q42493019 | Human Mediator enhances basal transcription by facilitating recruitment of transcription factor IIB during preinitiation complex assembly |
| Q24324051 | Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors |
| Q35661538 | Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors |
| Q24310867 | Human mediator subunit MED26 functions as a docking site for transcription elongation factors |
| Q34610960 | Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator |
| Q36742839 | INO80 subfamily of chromatin remodeling complexes. |
| Q48038615 | Identification and analysis of homologues of Saccharomyces cerevisiae Spt3 suggest conserved functional domains |
| Q33958879 | Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae |
| Q28587897 | Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation |
| Q46042839 | Identification of Rox3 as a component of mediator and RNA polymerase II holoenzyme |
| Q34607707 | Identification of SAS4 and SAS5, two genes that regulate silencing in Saccharomyces cerevisiae |
| Q36560556 | Identification of a binding site in c-Ab1 tyrosine kinase for the C-terminal repeated domain of RNA polymerase II. |
| Q24651940 | Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex |
| Q22253992 | Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb |
| Q35748747 | Identification of a regulator of transcription elongation as an accessory factor for the human Mediator coactivator. |
| Q24535680 | Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator |
| Q35190927 | Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition |
| Q33965153 | Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae |
| Q52566722 | Identification of highly conserved amino-terminal segments of dTAFII230 and yTAFII145 that are functionally interchangeable for inhibiting TBP-DNA interactions in vitro and in promoting yeast cell growth in vivo. |
| Q27940073 | Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae |
| Q58322274 | Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome |
| Q27931755 | Identification of the gene (SSU71/TFG1) encoding the largest subunit of transcription factor TFIIF as a suppressor of a TFIIB mutation in Saccharomyces cerevisiae |
| Q28277858 | Identification, purification, and characterization of a PA700-dependent activator of the proteasome |
| Q40019304 | Identifying a species-specific region of yeast TF11B in vivo |
| Q22009365 | Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators |
| Q22008534 | Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes |
| Q71747838 | Immunoaffinity purification of RNA polymerase II and transcription factors using polyol-responsive monoclonal antibodies |
| Q27938987 | Impaired core promoter recognition caused by novel yeast TAF145 mutations can be restored by creating a canonical TATA element within the promoter region of the TUB2 gene |
| Q26781182 | Importance of Mediator complex in the regulation and integration of diverse signaling pathways in plants |
| Q24551113 | In vivo requirement of activator-specific binding targets of mediator |
| Q34563248 | Independent recruitment of mediator and SAGA by the activator Met4 |
| Q38303101 | Influenza virus RNA polymerase PA subunit is a novel serine protease with Ser624 at the active site |
| Q24338780 | Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II |
| Q44991848 | Interaction between acidic transcriptional activation domains of herpes simplex virus activator protein VP16 and transcriptional initiation factor IID. |
| Q64114119 | Interaction map of Arabidopsis Mediator complex expounding its topology |
| Q24670740 | Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response |
| Q41791540 | Interaction of PC4 with melted DNA inhibits transcription |
| Q27938465 | Interaction of a transcriptional repressor with the RNA polymerase II holoenzyme plays a crucial role in repression |
| Q28249621 | Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators |
| Q28299369 | Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators |
| Q27679041 | Interaction of the Mediator Head Module with RNA Polymerase II |
| Q24654156 | Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF |
| Q24314697 | Interaction of thyroid-hormone receptor with a conserved transcriptional mediator |
| Q28539189 | Interaction studies of the human and Arabidopsis thaliana Med25-ACID proteins with the herpes simplex virus VP16- and plant-specific Dreb2a transcription factors |
| Q24313335 | Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor |
| Q42137229 | Interactions between DNA, transcriptional regulator Dreb2a and the Med25 mediator subunit from Arabidopsis thaliana involve conformational changes |
| Q27939381 | Interdependent recruitment of SAGA and Srb mediator by transcriptional activator Gcn4p |
| Q33775117 | Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme |
| Q58422524 | Introduction to the Thematic Minireview Series: Chromatin and transcription |
| Q27935508 | Isolation and characterization of TAF25, an essential yeast gene that encodes an RNA polymerase II-specific TATA-binding protein-associated factor |
| Q22008025 | Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation |
| Q28586142 | Isolation of mouse TFIID and functional characterization of TBP and TFIID in mediating estrogen receptor and chromatin transcription |
| Q27932286 | Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation |
| Q38929299 | Kin28 regulates the transient association of Mediator with core promoters |
| Q42058280 | Kinase activity and phosphorylation of the largest subunit of TFIIF transcription factor |
| Q41941071 | Large-scale screening of yeast mutants for sensitivity to the IMP dehydrogenase inhibitor 6-azauracil |
| Q48354638 | Lasker Basic Medical Research Award. The eukaryotic transcriptional machinery: complexities and mechanisms unforeseen |
| Q34318190 | MC EMiNEM maps the interaction landscape of the Mediator |
| Q24554446 | MCM proteins are associated with RNA polymerase II holoenzyme |
| Q24306465 | MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription |
| Q35054391 | MED29, a component of the mediator complex, possesses both oncogenic and tumor suppressive characteristics in pancreatic cancer |
| Q24630118 | Mammalian Sug1 and c-Fos in the nuclear 26S proteasome |
| Q24657915 | Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II |
| Q24681762 | Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways |
| Q38077643 | Mechanisms of Mediator complex action in transcriptional activation. |
| Q33892757 | Mechanisms of gene regulation by vitamin D(3) receptor: a network of coactivator interactions. |
| Q41066911 | Mechanisms of transcription complex assembly |
| Q41441677 | Mechanisms of transcriptional activation: differences and similarities between yeast, Drosophila, and man. |
| Q34302565 | Med5(Nut1) and Med17(Srb4) are direct targets of mediator histone H4 tail interactions |
| Q37429800 | Med8, Med18, and Med20 subunits of the Mediator head domain are interdependent upon each other for folding and complex formation |
| Q27933388 | Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes |
| Q37097833 | Mediating lipid biosynthesis: implications for cardiovascular disease |
| Q42734523 | Mediator Undergoes a Compositional Change during Transcriptional Activation. |
| Q42482086 | Mediator and TFIIH govern carboxyl-terminal domain-dependent transcription in yeast extracts |
| Q36129156 | Mediator and the mechanism of transcriptional activation |
| Q27930405 | Mediator as a general transcription factor |
| Q41627698 | Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly. |
| Q27931540 | Mediator complex association with constitutively transcribed genes in yeast |
| Q34348002 | Mediator complex dependent regulation of cardiac development and disease |
| Q37175103 | Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes |
| Q34245346 | Mediator complexes and transcription. |
| Q34961833 | Mediator directs co-transcriptional heterochromatin assembly by RNA interference-dependent and -independent pathways |
| Q40663023 | Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo |
| Q52569557 | Mediator is a transducer of Wnt/beta-catenin signaling. |
| Q37327569 | Mediator is an intrinsic component of the basal RNA polymerase II machinery in vivo. |
| Q47383454 | Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system. |
| Q26800203 | Mediator kinase module and human tumorigenesis |
| Q22065418 | Mediator of Transcriptional Regulation |
| Q34790743 | Mediator protein mutations that selectively abolish activated transcription |
| Q42508865 | Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock |
| Q28206442 | Mediator--a universal complex in transcriptional regulation |
| Q26995848 | Mediator-dependent nuclear receptor function |
| Q41756522 | Mediator-nucleosome interaction |
| Q48041468 | Members of the AAA-gene family are involved in early embryogenesis of vertebrates |
| Q35044194 | Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells |
| Q24649912 | Minimal components of the RNA polymerase II transcription apparatus determine the consensus TATA box |
| Q24797641 | Modular decomposition of protein-protein interaction networks |
| Q91894104 | Molecular and Phylogenetic Analyses of the Mediator Subunit Genes in Solanum lycopersicum |
| Q34495543 | Molecular architecture of the yeast Mediator complex |
| Q40416383 | Molecular biology of proteasomes |
| Q27934831 | Molecular characterization of Saccharomyces cerevisiae TFIID. |
| Q39528206 | Molecular genetic dissection of TAF25, an essential yeast gene encoding a subunit shared by TFIID and SAGA multiprotein transcription factors |
| Q29620260 | Molecular genetics of the RNA polymerase II general transcriptional machinery |
| Q38624791 | Molecular mechanism of the priming by jasmonic acid of specific dehydration stress response genes in Arabidopsis |
| Q30857009 | Mouse hepatocyte growth factor activator gene: its expression not only in the liver but also in the gastrointestinal tract. |
| Q22122454 | Multi-protein complexes in eukaryotic gene transcription |
| Q50335765 | Multimeric Coactivator Complexes for Steroid/Nuclear Receptors |
| Q34388525 | Multiple interactions between hTAFII55 and other TFIID subunits. Requirements for the formation of stable ternary complexes between hTAFII55 and the TATA-binding protein |
| Q40020901 | Multiple phosphorylated forms of the Saccharomyces cerevisiae Mcm1 protein include an isoform induced in response to high salt concentrations |
| Q39716020 | Mutations in target DNA elements of yeast HAP1 modulate its transcriptional activity without affecting DNA binding |
| Q42494682 | Mutations in the TATA-binding protein, affecting transcriptional activation, show synthetic lethality with the TAF145 gene lacking the TAF N-terminal domain in Saccharomyces cerevisiae |
| Q27932095 | Mutations in the histone fold domain of the TAF12 gene show synthetic lethality with the TAF1 gene lacking the TAF N-terminal domain (TAND) by different mechanisms from those in the SPT15 gene encoding the TATA box-binding protein (TBP) |
| Q42524559 | Mutations in the yeast SRB2 general transcription factor suppress hpr1-induced recombination and show defects in DNA repair |
| Q47651351 | Mutual targeting of mediator and the TFIIH kinase Kin28. |
| Q28282085 | NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription |
| Q27933037 | Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase |
| Q74460891 | Negative regulation of transcription by the yeast global transcription factors, Gal11 and Sin4 |
| Q71533736 | New chemistry for the study of multiprotein complexes: the six-histidine tag as a receptor for a protein crosslinking reagent |
| Q35120022 | Nonproteolytic roles of 19S ATPases in transcription of CIITApIV genes |
| Q40731209 | Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells |
| Q33757699 | Novel critical role of a human Mediator complex for basal RNA polymerase II transcription |
| Q35423214 | Novel role for mediator complex subunit Srb5/Med18 in termination of transcription |
| Q33745092 | Nuclear receptor cofactors as chromatin remodelers |
| Q35805048 | Nuclear receptor-mediated transactivation through interaction with Sp proteins |
| Q28074780 | Nucleosome distortion as a possible mechanism of transcription activation domain function |
| Q46552388 | Nucleotide requirements for activated RNA polymerase II open complex formation in vitro |
| Q45007503 | On the mechanism of constitutive Pdr1 activator-mediated PDR5 transcription in Saccharomyces cerevisiae: evidence for enhanced recruitment of coactivators and altered nucleosome structures |
| Q37912723 | Origins and activity of the Mediator complex |
| Q35190358 | P-TEFb kinase recruitment and function at heat shock loci |
| Q50457007 | PHYTOCHROME AND FLOWERING TIME1/MEDIATOR25 Regulates Lateral Root Formation via Auxin Signaling in Arabidopsis |
| Q39163086 | PIC Activation through Functional Interplay between Mediator and TFIIH. |
| Q34159503 | PRIC295, a Nuclear Receptor Coactivator, Identified from PPAR-Interacting Cofactor Complex |
| Q36557179 | Paf1p, an RNA polymerase II-associated factor in Saccharomyces cerevisiae, may have both positive and negative roles in transcription |
| Q36788358 | Partial truncation of the yeast RNA polymerase II carboxyl-terminal domain preferentially reduces expression of glycolytic genes |
| Q30870486 | Peptides selected to bind the Gal80 repressor are potent transcriptional activation domains in yeast |
| Q29541844 | Phosducin-like protein (PhLP), a regulator of Gβγ function, interacts with the proteasomal protein SUG1 |
| Q27938452 | Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation |
| Q71000825 | Phosphorylation dependence of the initiation of productive transcription of Balbiani ring 2 genes in living cells |
| Q34093159 | Phosphorylation in transcription: the CTD and more |
| Q44117541 | Physical association of the APIS complex and general transcription factors |
| Q42680736 | Physical linkage of the human growth hormone gene family and the thyroid hormone receptor interacting protein-1 gene on chromosome 17. |
| Q38546777 | Plant Mediator complex and its critical functions in transcription regulation |
| Q48362347 | Plant-plant interactions influence developmental phase transitions, grain productivity and root system architecture in Arabidopsis via auxin and PFT1/MED25 signalling. |
| Q36035454 | Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro |
| Q24548316 | Positive and negative TAF(II) functions that suggest a dynamic TFIID structure and elicit synergy with traps in activator-induced transcription |
| Q64945548 | Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex. |
| Q47829612 | Preinitation complex assembly: potentially a bumpy path. |
| Q44560693 | Preponderance of free mediator in the yeast Saccharomyces cerevisiae |
| Q41100064 | Promoters and basal transcription machinery in eubacteria and eukaryotes: concepts, definitions, and analogies |
| Q41032848 | Properties of PC4 and an RNA polymerase II complex in directing activated and basal transcription in vitro |
| Q45970861 | Protease footprinting analysis of ternary complex formation by human TFIIA. |
| Q71980463 | Proteasomes. Complex proteases lead to a new understanding of cellular regulation through proteolysis |
| Q36288964 | Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking |
| Q41362113 | Protein complexes for remodeling chromatin |
| Q24532199 | Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription |
| Q27932723 | Purification of active TFIID from Saccharomyces cerevisiae. Extensive promoter contacts and co-activator function |
| Q71747773 | Purification of human RNA polymerase II and general transcription factors |
| Q24650325 | Purification of transcription cofactor complex CRSP |
| Q41100162 | Purification of yeast RNA polymerase II holoenzymes |
| Q24317228 | Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes |
| Q36638798 | Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13. |
| Q39446590 | Quantitation of RNA polymerase II and its transcription factors in an HeLa cell: little soluble holoenzyme but significant amounts of polymerases attached to the nuclear substructure |
| Q41076429 | Quantitation of putative activator-target affinities predicts transcriptional activating potentials |
| Q43760093 | Quantitation of the RNA polymerase II transcription machinery in yeast |
| Q41472569 | Quantitative analysis of the transcription control mechanism |
| Q35182494 | Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors |
| Q36649506 | RAP74 induces promoter contacts by RNA polymerase II upstream and downstream of a DNA bend centered on the TATA box. |
| Q41480091 | REF4 and RFR1, subunits of the transcriptional coregulatory complex mediator, are required for phenylpropanoid homeostasis in Arabidopsis |
| Q22008019 | RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X protein |
| Q29540749 | RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template |
| Q48160282 | RNA polymerase I activation and hibernation: unique mechanisms for unique genes |
| Q41350631 | RNA polymerase II C-terminal domain required for enhancer-driven transcription |
| Q42099538 | RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion |
| Q33632354 | RNA polymerase II as a control panel for multiple coactivator complexes |
| Q33905060 | RNA polymerase II carboxy-terminal domain kinases: emerging clues to their function |
| Q39035964 | RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe |
| Q41477041 | RNA polymerase II holoenzyme and transcriptional regulation |
| Q70908581 | RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling |
| Q73205344 | RNA polymerase II holoenzyme recruitment is sufficient to remodel chromatin at the yeast PHO5 promoter |
| Q34067671 | RNA polymerase II holoenzymes and subcomplexes. |
| Q35566401 | RNA polymerase II transcription apparatus in Schizosaccharomyces pombe |
| Q27933821 | RSC, an essential, abundant chromatin-remodeling complex |
| Q36555479 | Recruiting TATA-binding protein to a promoter: transcriptional activation without an upstream activator |
| Q27631291 | Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain |
| Q28646829 | Recycling of the general transcription factors during RNA polymerase II transcription |
| Q53612627 | Redox regulation of the MED28 and MED32 mediator subunits is important for development and senescence. |
| Q34011585 | Region of yeast TAF 130 required for TFIID to associate with promoters |
| Q54228372 | Regulation of Mammalian Ribosomal Gene Transcription by RNA Polymerase I |
| Q36886903 | Regulation of SREBP-Mediated Gene Expression |
| Q37475205 | Regulation of metabolism by the Mediator complex |
| Q34816680 | Regulation of transcription elongation by phosphorylation |
| Q35762480 | Regulatory diversity among metazoan co-activator complexes |
| Q77485523 | Regulatory targets in the RNA polymerase II holoenzyme |
| Q33654886 | Relationships between proteasomes and viral gene products |
| Q38023496 | Reprogramming chromatin |
| Q28289887 | Requirement for TFIIH kinase activity in transcription by RNA polymerase II |
| Q32036964 | Requirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcription |
| Q24537229 | Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s |
| Q116170570 | Respiratory Syncytial Virus NS1 Protein Targets the Transactivator Binding Domain of MED25 |
| Q116166056 | Respiratory Syncytial virus NS1 protein targets the transactivator binding domain of MED25 |
| Q27932665 | Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. |
| Q36567515 | Retinoid X receptor:vitamin D3 receptor heterodimers promote stable preinitiation complex formation and direct 1,25-dihydroxyvitamin D3-dependent cell-free transcription |
| Q36556040 | Reversal of in vitro p53 squelching by both TFIIB and TFIID |
| Q46845661 | Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme |
| Q92486491 | Role of integrative structural biology in understanding transcriptional initiation |
| Q40598216 | Role of mediator in transcriptional activation by the aryl hydrocarbon receptor |
| Q24554282 | Role of metazoan mediator proteins in interferon-responsive transcription |
| Q37089752 | Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells |
| Q27929864 | SPN1, a conserved gene identified by suppression of a postrecruitment-defective yeast TATA-binding protein mutant |
| Q40019111 | SPT20/ADA5 encodes a novel protein functionally related to the TATA-binding protein and important for transcription in Saccharomyces cerevisiae |
| Q27933314 | SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II |
| Q36746977 | Saccharomyces cerevisiae phospholipase C regulates transcription of Msn2p-dependent stress-responsive genes |
| Q27939250 | Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex |
| Q40102537 | ScMED7, a sugarcane mediator subunit gene, acts as a regulator of plant immunity and is responsive to diverse stress and hormone treatments |
| Q96127211 | Selective Mediator dependence of cell-type-specifying transcription |
| Q37531957 | Separation of the transcriptional coactivator and antirepression functions of transcription factor IIA |
| Q42439710 | Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription |
| Q34472506 | Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module |
| Q24530953 | Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes |
| Q37228807 | Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity |
| Q37835470 | Single-molecule studies of RNA polymerase: one singular sensation, every little step it takes |
| Q37073125 | Site-specific Srb10-dependent phosphorylation of the yeast Mediator subunit Med2 regulates gene expression from the 2-microm plasmid |
| Q36652659 | Slow dimer dissociation of the TATA binding protein dictates the kinetics of DNA binding |
| Q64053367 | Smad7:β-catenin complex regulates myogenic gene transcription |
| Q41370397 | Small molecule probes to target the human Mediator complex |
| Q74754870 | Small-molecule-based strategies for controlling gene expression |
| Q27670982 | Solution NMR structure of MED25(391–543) comprising the activator-interacting domain (ACID) of human mediator subunit 25 |
| Q41980416 | Spe3, which encodes spermidine synthase, is required for full repression through NRE(DIT) in Saccharomyces cerevisiae |
| Q90471342 | Specific functions for Mediator complex subunits from different modules in the transcriptional response of Arabidopsis thaliana to abiotic stress |
| Q24540125 | Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD |
| Q36254517 | Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA |
| Q27933861 | Srb/mediator proteins interact functionally and physically with transcriptional repressor Sfl1. |
| Q27932440 | Srb5/Med18-mediated termination of transcription is dependent on gene looping |
| Q27930238 | Srb7p is essential for the activation of a subset of genes |
| Q89947701 | Stem rust resistance in wheat is suppressed by a subunit of the mediator complex |
| Q33813416 | Strategies for transcriptional activation by steroid/nuclear receptors |
| Q42041363 | Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator |
| Q36024269 | Structural basis of eukaryotic gene transcription |
| Q35840815 | Structural organization of yeast and mammalian mediator complexes |
| Q27728022 | Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex |
| Q27674569 | Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II |
| Q51769224 | Structures of transcription pre-initiation complex with TFIIH and Mediator. |
| Q24304075 | Subcellular localization of RPB5-mediating protein and its putative functional partner |
| Q24298604 | Subunit architecture and functional modular rearrangements of the transcriptional mediator complex |
| Q36555713 | Sug1 modulates yeast transcription activation by Cdc68. |
| Q41932256 | Suppression analysis reveals a functional difference between the serines in positions two and five in the consensus sequence of the C-terminal domain of yeast RNA polymerase II |
| Q33966150 | Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure. |
| Q36300660 | Synergistic and promoter-selective activation of transcription by recruitment of transcription factors TFIID and TFIIB. |
| Q41064463 | Synergistic enhancement of both initiation and elongation by acidic transcription activation domains. |
| Q27938743 | Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo |
| Q40511151 | Systems-level analyses identify extensive coupling among gene expression machines |
| Q42459088 | TAFII-independent activation mediated by human TBP in the presence of the positive cofactor PC4 |
| Q28581872 | TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism |
| Q33962132 | TATA-binding protein mutants that increase transcription from enhancerless and repressed promoters in vivo |
| Q37695809 | TBP mutants defective in activated transcription in vivo. |
| Q33832058 | TBP-associated factors (TAFIIs): multiple, selective transcriptional mediators in common complexes |
| Q42522148 | TBP-associated factors are not generally required for transcriptional activation in yeast |
| Q27935740 | TFG/TAF30/ANC1, a component of the yeast SWI/SNF complex that is similar to the leukemogenic proteins ENL and AF-9. |
| Q40018632 | TFIIB-directed transcriptional activation by the orphan nuclear receptor hepatocyte nuclear factor 4. |
| Q24674080 | TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA |
| Q35207267 | TFIID-specific yeast TAF40 is essential for the majority of RNA polymerase II-mediated transcription in vivo |
| Q28138931 | TFIIH is negatively regulated by cdk8-containing mediator complexes |
| Q33671365 | TFIIH phosphorylation of the Pol II CTD stimulates mediator dissociation from the preinitiation complex and promoter escape. |
| Q41099885 | TFIIH: a key component in multiple DNA transactions |
| Q38008913 | TFIIH: when transcription met DNA repair. |
| Q35143140 | TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution |
| Q27934702 | Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases |
| Q33753938 | Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions |
| Q41535672 | The 26S proteasome: a dynamic structure |
| Q42479323 | The Arabidopsis Mediator Complex Subunit16 Is a Key Component of Basal Resistance against the Necrotrophic Fungal Pathogen Sclerotinia sclerotiorum. |
| Q42437535 | The Arabidopsis Mediator complex subunits MED14/SWP and MED16/SFR6/IEN1 differentially regulate defense gene expression in plant immune responses |
| Q87440912 | The Arabidopsis mediator complex subunit16 positively regulates salicylate-mediated systemic acquired resistance and jasmonate/ethylene-induced defense pathways |
| Q52549901 | The Aspergillus parasiticus protein AFLJ interacts with the aflatoxin pathway-specific regulator AFLR. |
| Q28570708 | The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins |
| Q52119435 | The C-terminal domain of the largest subunit of RNA polymerase II is required for stationary phase entry and functionally interacts with the Ras/PKA signaling pathway. |
| Q44030852 | The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation |
| Q43649651 | The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis |
| Q33887586 | The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex |
| Q34422408 | The DNA binding and activation domains of Gal4p are sufficient for conveying its regulatory signals |
| Q47072545 | The DUG gene of Drosophila melanogaster encodes a structural and functional homolog of the S. cerevisiae SUG1 predicted ATPase associated with the 26S proteasome. |
| Q57886292 | The Elp2 Subunit of Elongator and Elongating RNA Polymerase II Holoenzyme Is a WD40 Repeat Protein |
| Q33772811 | The Gcn4p activation domain interacts specifically in vitro with RNA polymerase II holoenzyme, TFIID, and the Adap-Gcn5p coactivator complex |
| Q24605935 | The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II |
| Q48874029 | The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans |
| Q24609120 | The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain |
| Q37201218 | The Med1 subunit of the mediator complex induces liver cell proliferation and is phosphorylated by AMP kinase |
| Q27937894 | The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression. |
| Q36938987 | The Mediator Complex and Lipid Metabolism |
| Q38043907 | The Mediator complex and transcription elongation |
| Q28299679 | The Mediator complex and transcription regulation |
| Q51849831 | The Mediator complex in plants: structure, phylogeny, and expression profiling of representative genes in a dicot (Arabidopsis) and a monocot (rice) during reproduction and abiotic stress. |
| Q35131077 | The Mediator complex of Caenorhabditis elegans: insights into the developmental and physiological roles of a conserved transcriptional coregulator |
| Q36119053 | The Mediator complex subunit 8 regulates organ size in Arabidopsis thaliana |
| Q26849595 | The Mediator complex: a central integrator of transcription |
| Q28623816 | The Oct-1 POU domain activates snRNA gene transcription by contacting a region in the SNAPc largest subunit that bears sequence similarities to the Oct-1 coactivator OBF-1 |
| Q28623435 | The Oct-1 POU-specific domain can stimulate small nuclear RNA gene transcription by stabilizing the basal transcription complex SNAPc |
| Q37671309 | The Paf1 complex: platform or player in RNA polymerase II transcription? |
| Q29622942 | The RNA polymerase II holoenzyme and its implications for gene regulation |
| Q39721405 | The RNA polymerase II preinitiation complex formed in the presence of ATP |
| Q33860695 | The SRC family of nuclear receptor coactivators |
| Q27939572 | The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo. |
| Q27937037 | The Saccharomyces cerevisiae Srb8-Srb11 complex functions with the SAGA complex during Gal4-activated transcription |
| Q27937408 | The Soh1/MED31 protein is an ancient component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator |
| Q38977021 | The Structural Basis of Transcription: 10 Years After the Nobel Prize in Chemistry |
| Q92651096 | The Structures of Eukaryotic Transcription Pre-initiation Complexes and Their Functional Implications |
| Q27932964 | The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II. |
| Q24298533 | The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis |
| Q28592968 | The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development |
| Q35910444 | The Transition of Poised RNA Polymerase II to an Actively Elongating State Is a "Complex" Affair |
| Q24336424 | The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor |
| Q33731470 | The YEATS domain of Taf14 in Saccharomyces cerevisiae has a negative impact on cell growth |
| Q33794695 | The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo |
| Q37467909 | The basal initiation machinery: beyond the general transcription factors |
| Q96131261 | The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis |
| Q78680279 | The co-activator p300 associates physically with and can mediate the action of the distal enhancer of the FGF-4 gene |
| Q24598984 | The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation |
| Q41596446 | The complex structure and function of Mediator |
| Q35127464 | The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II. |
| Q42314726 | The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription |
| Q52319133 | The essential and multi-functional TFIIH complex. |
| Q41756430 | The estrogen receptor gene: promoter organization and expression |
| Q34229719 | The functions of Mediator in Candida albicans support a role in shaping species-specific gene expression |
| Q28619324 | The general transcription factors IIA, IIB, IIF, and IIE are required for RNA polymerase II transcription from the human U1 small nuclear RNA promoter |
| Q37528878 | The head module of Mediator directs activation of preloaded RNAPII in vivo |
| Q27930236 | The histone H3-like TAF is broadly required for transcription in yeast |
| Q42082510 | The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function |
| Q28276700 | The human Mediator complex: a versatile, genome-wide regulator of transcription |
| Q22001483 | The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex |
| Q24646774 | The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme |
| Q28304955 | The mammalian Mediator complex |
| Q35669882 | The mediator complex |
| Q43293809 | The mediator complex subunit PFT1 is a key regulator of jasmonate-dependent defense in Arabidopsis |
| Q36029267 | The mediator of RNA polymerase II. |
| Q37799722 | The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation |
| Q48554301 | The molecular basis of eucaryotic transcription |
| Q24681447 | The molecular basis of eukaryotic transcription |
| Q48328874 | The molecular basis of eukaryotic transcription (Nobel Lecture). |
| Q46371249 | The photoactivated cross-linking of recombinant C-terminal domain to proteins in a HeLa cell transcription extract that comigrate with transcription factors IIE and IIF. |
| Q92026233 | The plant Mediator complex and its role in jasmonate signaling |
| Q47168946 | The pre-mRNA retention and splicing complex controls expression of the Mediator subunit Med20. |
| Q35887891 | The product of the adenovirus intermediate gene IX is a transcriptional activator. |
| Q25255839 | The proteasomal ATPase complex is required for stress-induced transcription in yeast |
| Q46030222 | The repetitive C‐terminal domain of RNA polymerase II: Multiple conformational states drive the transcription cycle |
| Q27932113 | The rye mutants identify a role for Ssn/Srb proteins of the RNA polymerase II holoenzyme during stationary phase entry in Saccharomyces cerevisiae |
| Q38319833 | The structural and functional role of Med5 in the yeast Mediator tail module |
| Q40395489 | The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance |
| Q24652864 | The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids |
| Q22001451 | The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1 |
| Q38340138 | The type of basal promoter determines the regulated or constitutive mode of transcription in the common control region of the yeast gene pair GCY1/RIO1. |
| Q27934704 | The yeast GAL11 protein binds to the transcription factor IIE through GAL11 regions essential for its in vivo function |
| Q27936053 | The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo |
| Q27932742 | The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex |
| Q24532893 | Three transitions in the RNA polymerase II transcription complex during initiation |
| Q41361209 | Topological localization of the carboxyl-terminal domain of RNA polymerase II in the initiation complex |
| Q37166062 | Toward accurate reconstruction of functional protein networks |
| Q48174606 | Toward understanding of the mechanisms of Mediator function in vivo: Focus on the preinitiation complex assembly |
| Q74033390 | Towards a minimal motif for artificial transcriptional activators |
| Q38348614 | Transcription Activation by a PNA-Peptide Chimera in a Mammalian Cell Extract |
| Q36139169 | Transcription Factor and Polymerase Recruitment, Modification, and Movement on dhsp70 In Vivo in the Minutes following Heat Shock |
| Q47858026 | Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs |
| Q34952743 | Transcription activation: unveiling the essential nature of TFIID. |
| Q27934706 | Transcription factor TFIIH is required for promoter melting in vivo |
| Q41442509 | Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes |
| Q55036574 | Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region. |
| Q29618752 | Transcription regulation and animal diversity |
| Q50057687 | Transcription regulation by the Mediator complex |
| Q37353465 | Transcription syndromes and the role of RNA polymerase II general transcription factors in human disease |
| Q41044026 | Transcription: basal factors and activation. |
| Q73159428 | Transcription: why are TAFs essential? |
| Q40494477 | Transcriptional Activation: Tuning-up transcription |
| Q36573748 | Transcriptional activation by TFIIB mutants that are severely impaired in interaction with promoter DNA and acidic activation domains |
| Q35058398 | Transcriptional activation by artificial recruitment in yeast is influenced by promoter architecture and downstream sequences |
| Q47991678 | Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo |
| Q40935476 | Transcriptional activation. A holistic view of the complex. |
| Q28486904 | Transcriptional activators control splicing and 3'-end cleavage levels |
| Q36053034 | Transcriptional activities of retinoic acid receptors |
| Q40951549 | Transcriptional coactivators in yeast and beyond |
| Q24530710 | Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes |
| Q36558597 | Transcriptional corepression in vitro: a Mot1p-associated form of TATA-binding protein is required for repression by Leu3p |
| Q73019085 | Transcriptional enhancement by acidic activators |
| Q77388114 | Transcriptional functions of a new mammalian TATA-binding protein-related factor |
| Q41674567 | Transcriptional interference caused by GCN4 overexpression reveals multiple interactions mediating transcriptional activation |
| Q36024274 | Transcriptional regulation and the role of diverse coactivators in animal cells |
| Q33904338 | Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells |
| Q35964659 | Transcriptional regulation: contending with complexity |
| Q37256618 | Transcriptional regulators of seven yeast species: comparative genome analysis. Review |
| Q35962538 | Transcriptional repression at a distance through exclusion of activator binding in vivo |
| Q34035076 | Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition. |
| Q57166686 | Transcriptome Analysis of Four Mediator Tail Mutants Reveals Overlapping and Unique Functions in Gene Regulation |
| Q34963539 | Transient-state kinetic analysis of transcriptional activator·DNA complexes interacting with a key coactivator |
| Q64231631 | Twenty years of Mediator complex structural studies |
| Q29618064 | Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome |
| Q27930891 | Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF. |
| Q44341024 | Two forms of RNA polymerase II holoenzyme display different abundance during the cell cycle. |
| Q27935243 | Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage |
| Q28507179 | Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice |
| Q41056225 | Ultraviolet radiation-induced ubiquitination and proteasomal degradation of the large subunit of RNA polymerase II. Implications for transcription-coupled DNA repair |
| Q42966234 | Underproduction of the largest subunit of RNA polymerase II causes temperature sensitivity, slow growth, and inositol auxotrophy in Saccharomyces cerevisiae |
| Q34195277 | Understanding large multiprotein complexes: applying a multiple allosteric networks model to explain the function of the Mediator transcription complex |
| Q40423733 | Unraveling the mechanism of a potent transcriptional activator |
| Q92684595 | Unveiling the gene regulatory landscape in diseases through the identification of DNase I-hypersensitive sites |
| Q40395601 | Variable pause positions of RNA polymerase II lie proximal to the c-myc promoter irrespective of transcriptional activity. |
| Q36994683 | Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation |
| Q34613177 | Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8 |
| Q38307266 | Virtually unidirectional binding of TBP to the AdMLP TATA box within the quaternary complex with TFIIA and TFIIB. |
| Q37788083 | Whether to target single or multiple CDKs for therapy? That is the question |
| Q34950050 | YEATS domain proteins: a diverse family with many links to chromatin modification and transcription. |
| Q42497133 | Yeast GAL11 protein stimulates basal transcription in a gene-specific manner by a mechanism distinct from that by DNA-bound activators |
| Q27934583 | Yeast Gal11 and transcription factor IIE function through a common pathway in transcriptional regulation |
| Q41100155 | Yeast RNA polymerase II holoenzyme |
| Q24563103 | Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4 |
| Q27938810 | Yeast TAF(II)145 required for transcription of G1/S cyclin genes and regulated by the cellular growth state |
| Q29622932 | Yeast carbon catabolite repression |
| Q38615074 | Yeast cycloheximide-resistant crl mutants are proteasome mutants defective in protein degradation |
| Q33739221 | Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. |
| Q26749291 | Zooming in on Transcription Preinitiation |
| Q73728723 | [Activation of transcription in eukaryotic cells: interactions between transcription factors and components of the basal transcriptional mechanism] |
| Q28115204 | cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p |
| Q24562004 | hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II |
| Q24602633 | mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain |
| Q41075171 | pX, the HBV-encoded coactivator, interacts with components of the transcription machinery and stimulates transcription in a TAF-independent manner |
| Q77652532 | yTAFII61 has a general role in RNA polymerase II transcription and is required by Gcn4p to recruit the SAGA coactivator complex |
Search more.