A class of activation domains interacts directly with TFIIA and stimulates TFIIA-TFIID-promoter complex assembly

scientific article published on November 1995

A class of activation domains interacts directly with TFIIA and stimulates TFIIA-TFIID-promoter complex assembly is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.15.11.6465
P932PMC publication ID230897
P698PubMed publication ID7565798

P2093author name stringN Kobayashi
A J Berk
T G Boyer
P2860cites workInteraction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factorQ24313335
Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcriptionQ24318300
Activation of the TFIID-TFIIA complex with HMG-2Q24324542
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repressionQ24336035
Molecular cloning of the small (gamma) subunit of human TFIIA reveals functions critical for activated transcriptionQ24336744
Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcriptionQ24336780
Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcriptionQ24337785
Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activatorQ24563645
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53Q24609153
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene productQ27860841
Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB.Q42502083
DNA topoisomerase I is involved in both repression and activation of transcriptionQ42508509
Physical Analysis of Transcription Preinitiation Complex Assembly on a Class II Gene PromoterQ45226839
Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factorQ46050449
Potentiation of RNA polymerase II transcription by Gal4-VP16 during but not after DNA replication and chromatin assemblyQ46055907
Histones and the regulation of heterochromatin in yeast.Q46058291
The acidic activator GAL4-AH can stimulate polymerase II transcription by promoting assembly of a closed complex requiring TFIID and TFIIAQ46406435
The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interactionQ46609056
Activator-induced conformational change in general transcription factor TFIIB.Q53939616
Reduced binding of TFIID to transcriptionally compromised mutants of VP16.Q54251780
A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives.Q54713263
Mechanism of action of a yeast activator: Direct effect of GAL4 derivatives on mammalian TFIID-promoter interactionsQ58422728
Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activationQ59057687
Eukaryotic activators function during multiple steps of preinitiation complex assemblyQ59058665
Binding of general transcription factor TFIIB to an acidic activating regionQ59058683
Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIIDQ59070657
Functional interaction of adenovirus E1A with holo-TFIIDQ64377679
An ATP-dependent inhibitor of TBP binding to DNAQ64377765
Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase IIQ69442826
Mechanism of action of an acidic transcriptional activator in vitroQ70113517
Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding proteinQ70550409
A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formationQ72718834
Herpes simplex genes: the blueprint of a successful human pathogenQ72755042
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.Q27930548
Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeastQ27933378
A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIAQ28255676
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II)Q28264307
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activationQ28303864
p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60Q28304820
TBP, a universal eukaryotic transcription factor?Q28626484
Five intermediate complexes in transcription initiation by RNA polymerase IIQ29616444
An RNA polymerase II holoenzyme responsive to activatorsQ29620210
Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivatorsQ29620376
Deletion analysis of GAL4 defines two transcriptional activating segmentsQ29620547
Product review. New mammalian expression vectorsQ29620743
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expressionQ34555693
Activation of class II gene transcription by regulatory factors is potentiated by a novel activityQ34855093
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activationQ34920038
The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding proteinQ35117818
Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activationQ35219225
Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormoneQ36556508
The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcriptionQ36685220
Characterization of the Epstein-Barr virus BZLF1 protein transactivation domainQ36690559
Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.Q36710645
Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complexQ36754140
Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitroQ36794743
In vitro transcriptional activation, dimerization, and DNA-binding specificity of the Epstein-Barr virus Zta proteinQ36806719
Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB.Q36824974
Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assayQ37522721
Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IIDQ37531197
Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoterQ38325574
Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complexQ38346478
Transcriptional Activation: Tuning-up transcriptionQ40494477
The ZEBRA activation domain: modular organization and mechanism of actionQ40656689
The acidic activation domain of the Epstein-Barr virus transcription factor R interacts in vitro with both TBP and TFIIB and is cell-specifically potentiated by a proline-rich region.Q41582734
Isolation of two genes that encode subunits of the yeast transcription factor IIAQ42459697
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complexQ42468497
Family of proteins that interact with TFIID and regulate promoter activityQ42473645
Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomesQ42475419
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activatorsQ42491732
Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.Q42492924
Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activationQ42492930
The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactionsQ42501935
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)6465-6473
P577publication date1995-11-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleA class of activation domains interacts directly with TFIIA and stimulates TFIIA-TFIID-promoter complex assembly
P478volume15

Reverse relations

cites work (P2860)
Q42280074A TAF4 coactivator function for E proteins that involves enhanced TFIID binding
Q42514084A heterochromatin-dependent transcription machinery drives piRNA expression.
Q30829987A testis-specific transcription factor IIA (TFIIAtau) stimulates TATA-binding protein-DNA binding and transcription activation
Q50983487A transcription factor IIA-binding site differentially regulates RNA polymerase II-mediated transcription in a promoter context-dependent manner.
Q35881137Alteration of a single serine in the basic domain of the Epstein-Barr virus ZEBRA protein separates its functions of transcriptional activation and disruption of latency
Q27938223An activator target in the RNA polymerase II holoenzyme
Q24657618An interplay between TATA box-binding protein and transcription factors IIE and IIA modulates DNA binding and transcription
Q27937697Analysis of TFIIA function In vivo: evidence for a role in TATA-binding protein recruitment and gene-specific activation
Q39583813Association of transcription factor IIA with TATA binding protein is required for transcriptional activation of a subset of promoters and cell cycle progression in Saccharomyces cerevisiae
Q35660192Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters
Q47977731Characterization and functional analysis of Arabidopsis TFIIA reveal that the evolutionarily unconserved region of the large subunit has a transcription activation domain.
Q24314747Cloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1.
Q33714149Common effects of acidic activators on large-scale chromatin structure and transcription
Q28145475Control of gene expression through regulation of the TATA-binding protein
Q39445508Corepressor required for adenovirus E1B 55,000-molecular-weight protein repression of basal transcription
Q39575245DA-complex assembly activity required for VP16C transcriptional activation
Q40551612Differential cellular requirements for activation of herpes simplex virus type 1 early (tk) and late (gC) promoters by ICP4.
Q28115255Direct interaction of TFIIB and the IE protein of equine herpesvirus 1 is required for maximal trans-activation function
Q30313329Dissection of TALE-dependent gene activation reveals that they induce transcription cooperatively and in both orientations
Q64907692Distinct requirements of linker DNA and transcriptional activators in promoting SAGA-mediated nucleosome acetylation.
Q77785134EHV-1 EICP22 protein sequences that mediate its physical interaction with the immediate-early protein are not sufficient to enhance the trans-activation activity of the IE protein
Q42411044Effective formation of the segregation-competent complex determines successful partitioning of the bovine papillomavirus genome during cell division
Q28296028Efficient Binding of NC2⋅TATA-binding Protein to DNA in the Absence of TATA
Q36424417Epstein-Barr virus immunossuppression of innate immunity mediated by phagocytes
Q45983312Eukaryotic transcription: the core of eukaryotic gene activation.
Q34640455Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II
Q50446313HEMERA Couples the Proteolysis and Transcriptional Activity of PHYTOCHROME INTERACTING FACTORs in Arabidopsis Photomorphogenesis.
Q33812313Herpes simplex virus type 1 ICP4 promotes transcription preinitiation complex formation by enhancing the binding of TFIID to DNA
Q26745059Herpesvirus Late Gene Expression: A Viral-Specific Pre-initiation Complex Is Key
Q41740213Hormone response units: one plus one equals more than two.
Q24644626Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells
Q35818739Identification of Promising Mutants Associated with Egg Production Traits Revealed by Genome-Wide Association Study.
Q33690825Identification of candidate epigenetic biomarkers for ovarian cancer detection
Q52566722Identification of highly conserved amino-terminal segments of dTAFII230 and yTAFII145 that are functionally interchangeable for inhibiting TBP-DNA interactions in vitro and in promoting yeast cell growth in vivo.
Q36048657Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants
Q75231689Interaction of Gal4p with components of transcription machinery in vivo
Q28249621Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators
Q36561858Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA
Q28539189Interaction studies of the human and Arabidopsis thaliana Med25-ACID proteins with the herpes simplex virus VP16- and plant-specific Dreb2a transcription factors
Q41361177Interactions of a DNA-bound transcriptional activator with the TBP-TFIIA-TFIIB-promoter quaternary complex
Q33713693Mapping and functional characterization of the TAF11 interaction with TFIIA.
Q33847734Mapping the sequences that mediate interaction of the equine herpesvirus 1 immediate-early protein and human TFIIB.
Q40443665Mechanism of synergy between TATA and initiator: synergistic binding of TFIID following a putative TFIIA-induced isomerization
Q54102655Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein.
Q41066911Mechanisms of transcription complex assembly
Q40022625Molecular architecture of the hsp70 promoter after deletion of the TATA box or the upstream regulation region
Q29620260Molecular genetics of the RNA polymerase II general transcriptional machinery
Q22122454Multi-protein complexes in eukaryotic gene transcription
Q24533544Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2
Q27642025Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes
Q42002467Nucleosome structure of the yeast CHA1 promoter: analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators.
Q39445227Phosphorylation of TFIIA stimulates TATA binding protein-TATA interaction and contributes to maximal transcription and viability in yeast
Q39574692Polymerase (Pol) III TATA box-binding protein (TBP)-associated factor Brf binds to a surface on TBP also required for activated Pol II transcription
Q36573810Promoter activity of Tat at steps subsequent to TATA-binding protein recruitment
Q45970861Protease footprinting analysis of ternary complex formation by human TFIIA.
Q35586902Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cells
Q41477041RNA polymerase II holoenzyme and transcriptional regulation
Q40023879Requirement for transcription factor IIA (TFIIA)-TFIID recruitment by an activator depends on promoter structure and template competition
Q34552116Role of TAF4 in transcriptional activation by Rta of Epstein-Barr Virus
Q37531957Separation of the transcriptional coactivator and antirepression functions of transcription factor IIA
Q36652659Slow dimer dissociation of the TATA binding protein dictates the kinetics of DNA binding
Q42834860Specific interaction with transcription factor IIA and localization of the mammalian TATA-binding protein-like protein (TLP/TRF2/TLF).
Q41817706Stabilized binding of TBP to the TATA box of herpes simplex virus type 1 early (tk) and late (gC) promoters by TFIIA and ICP4.
Q39583958Stepwise recruitment of components of the preinitiation complex by upstream activators in vivo
Q34087181Structural and functional interactions of transcription factor (TF) IIA with TFIIE and TFIIF in transcription initiation by RNA polymerase II.
Q24653925Structural changes in TAF4b-TFIID correlate with promoter selectivity
Q27666881Structure and VP16 binding of the Mediator Med25 activator interaction domain
Q37853081Structure and functions of powerful transactivators: VP16, MyoD and FoxA.
Q42459088TAFII-independent activation mediated by human TBP in the presence of the positive cofactor PC4
Q64377584TFIIA abrogates the effects of inhibition by HMGB1 but not E1A during the early stages of assembly of the transcriptional preinitiation complex
Q38313033TFIIA has activator-dependent and core promoter functions in vivo
Q33967253TFIIA interacts with TFIID via association with TATA-binding protein and TAF40
Q34718574TFIIA plays a role in the response to oxidative stress
Q73075615TFIIA regulates TBP and TFIID dimers
Q47677143TFIIA transcriptional activity is controlled by a 'cleave-and-run' Exportin-1/Taspase 1-switch.
Q39900716TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation
Q39752283TFIIB-facilitated recruitment of preinitiation complexes by a TAF-independent mechanism
Q52020747Testifying the rice bacterial blight resistance gene xa5 by genetic complementation and further analyzing xa5 (Xa5) in comparison with its homolog TFIIAgamma1.
Q34115151The H1 and H2 regions of the activation domain of herpes simplex virion protein 16 stimulate transcription through distinct molecular mechanisms
Q28623816The Oct-1 POU domain activates snRNA gene transcription by contacting a region in the SNAPc largest subunit that bears sequence similarities to the Oct-1 coactivator OBF-1
Q35889925The VP16 paradox: herpes simplex virus VP16 contains a long-range activation domain but within the natural multiprotein complex activates only from promoter-proximal positions
Q39444671The amino-terminal C/H1 domain of CREB binding protein mediates zta transcriptional activation of latent Epstein-Barr virus
Q35201509The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription
Q40985245The position of the ZEBRA activation domain does not influence its biological activity
Q74009630The stability of the TFIIA-TBP-DNA complex is dependent on the sequence of the TATAAA element
Q84767361Transcription activator-like type III effector AvrXa27 depends on OsTFIIAgamma5 for the activation of Xa27 transcription in rice that triggers disease resistance to Xanthomonas oryzae pv. oryzae
Q28272088Transcription factor IIA derepresses TATA-binding protein (TBP)-associated factor inhibition of TBP-DNA binding
Q24310214Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding
Q34608335Transcriptional activation in yeast cells lacking transcription factor IIA.
Q58049054Transcriptional activity of the TFIIA four-helix bundle in vivo
Q35127128Transcriptional coactivator PC4 stimulates promoter escape and facilitates transcriptional synergy by GAL4-VP16
Q35033134Transcriptional regulation by Modulo integrates meiosis and spermatid differentiation in male germ line
Q35973487Two type III effector genes of Xanthomonas oryzae pv. oryzae control the induction of the host genes OsTFIIAgamma1 and OsTFX1 during bacterial blight of rice
Q24548040Uncleaved TFIIA is a substrate for taspase 1 and active in transcription
Q36299140Upregulating endogenous genes by an RNA-programmable artificial transactivator
Q24810390cAMP-responsive element in TATA-less core promoter is essential for haploid-specific gene expression in mouse testis
Q38833599p53 Dynamically Directs TFIID Assembly on Target Gene Promoters
Q24550965p53 Stimulates TFIID-TFIIA-promoter complex assembly, and p53-T antigen complex inhibits TATA binding protein-TATA interaction