scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1045788393 |
P356 | DOI | 10.1038/368466A0 |
P3181 | OpenCitations bibliographic resource ID | 2110705 |
P698 | PubMed publication ID | 8133894 |
P2093 | author name string | Young RA | |
Koleske AJ | |||
P2860 | cites work | A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. | Q27931243 |
A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID. | Q27936818 | ||
DNA topology and a minimal set of basal factors for transcription by RNA polymerase II | Q28646851 | ||
Five intermediate complexes in transcription initiation by RNA polymerase II | Q29616444 | ||
A mediator required for activation of RNA polymerase II transcription in vitro | Q34095554 | ||
RNA polymerase B (II) and general transcription factors | Q34222071 | ||
Advances in RNA polymerase II transcription | Q35673499 | ||
A heteromeric transcription factor required for mammalian RNA polymerase II. | Q35870944 | ||
Dynamic interaction between a Drosophila transcription factor and RNA polymerase II. | Q36763575 | ||
Simple derivation of TFIID-dependent RNA polymerase II transcription systems from Schizosaccharomyces pombe and other organisms, and factors required for transcriptional activation | Q37158674 | ||
Yeast RNA polymerase II initiation factor e: isolation and identification as the functional counterpart of human transcription factor IIB | Q37317083 | ||
Initiation by yeast RNA polymerase II at the adenoviral major late promoter in vitro | Q38343145 | ||
General initiation factors for RNA polymerase II. | Q40835254 | ||
Isolation of two genes that encode subunits of the yeast transcription factor IIA | Q42459697 | ||
Physical Analysis of Transcription Preinitiation Complex Assembly on a Class II Gene Promoter | Q45226839 | ||
The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo. | Q45910393 | ||
Cloning of a subunit of yeast RNA polymerase II transcription factor b and CTD kinase | Q48158311 | ||
Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences | Q59074628 | ||
RNA polymerase II carboxy-terminal domain contributes to the response to multiple acidic activators in vitro | Q67782272 | ||
Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein | Q68133927 | ||
P433 | issue | 6470 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 466-9 | |
P577 | publication date | 1994-03-31 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | An RNA polymerase II holoenzyme responsive to activators | |
P478 | volume | 368 |
Q33368388 | A CTD function linking transcription to splicing |
Q54976735 | A Cotton Cyclin-Dependent Kinase E Confers Resistance to Verticillium dahliae Mediated by Jasmonate-Responsive Pathway. |
Q33651485 | A TATA-binding protein mutant defective for TFIID complex formation in vivo |
Q36556030 | A class of activation domains interacts directly with TFIIA and stimulates TFIIA-TFIID-promoter complex assembly |
Q27940291 | A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling |
Q34081613 | A conserved GA element in TATA-less RNA polymerase II promoters |
Q27935262 | A functional module of yeast mediator that governs the dynamic range of heat-shock gene expression |
Q30815733 | A genetic strategy to eliminate self-activator baits prior to high-throughput yeast two-hybrid screens |
Q27933520 | A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein. |
Q27939183 | A highly conserved domain of RNA polymerase II shares a functional element with acidic activation domains of upstream transcription factors |
Q28276653 | A human RNA polymerase II complex associated with SRB and DNA-repair proteins |
Q24522669 | A human RNA polymerase II complex containing factors that modify chromatin structure |
Q27930481 | A kinase-cyclin pair in the RNA polymerase II holoenzyme. |
Q34295542 | A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription |
Q24322024 | A mammalian SRB protein associated with an RNA polymerase II holoenzyme |
Q24324110 | A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains |
Q27936438 | A motif shared by TFIIF and TFIIB mediates their interaction with the RNA polymerase II carboxy-terminal domain phosphatase Fcp1p in Saccharomyces cerevisiae |
Q39722071 | A multiplicity of mediators: alternative forms of transcription complexes communicate with transcriptional regulators |
Q36561614 | A new class of activation-defective TATA-binding protein mutants: evidence for two steps of transcriptional activation in vivo |
Q22011164 | A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth |
Q22008779 | A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation |
Q22008652 | A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2 |
Q27936954 | A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination. |
Q35171792 | A regulatory shortcut between the Snf1 protein kinase and RNA polymerase II holoenzyme |
Q42479261 | A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation |
Q35154714 | A role of transcriptional activators as antirepressors for the autoinhibitory activity of TATA box binding of transcription factor IID. |
Q36565816 | A severely defective TATA-binding protein-TFIIB interaction does not preclude transcriptional activation in vivo |
Q38315368 | A single point mutation in TFIIA suppresses NC2 requirement in vivo |
Q40018556 | A three-step pathway of transcription initiation leading to promoter clearance at an activation RNA polymerase II promoter |
Q59071495 | A transcription reinitiation intermediate that is stabilized by activator |
Q24645448 | A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans |
Q42519847 | A yeast transcriptional stimulatory protein similar to human PC4. |
Q27939725 | ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3. |
Q27930121 | ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex |
Q27932447 | ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription |
Q53947997 | ATP-mediated activation of RNA polymerase II transcription complexes. |
Q36568453 | Accurate positioning of RNA polymerase II on a natural TATA-less promoter is independent of TATA-binding-protein-associated factors and initiator-binding proteins |
Q40445630 | Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast |
Q37297562 | Activation domain-mediated enhancement of activator binding to chromatin in mammalian cells |
Q36239308 | Activation of RNA polymerase II by topologically linked DNA-tracking proteins |
Q54567789 | Activation of prokaryotic transcription through arbitrary protein-protein contacts. |
Q47858055 | Activation of transcription in vitro by recruitment of the yeast RNA polymerase II holoenzyme |
Q24540745 | Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation |
Q38297759 | Additive activation of yeast LEU4 transcription by multiple cis elements |
Q73248351 | Affinity purification of a human RNA polymerase II complex using monoclonal antibodies against transcription factor IIF |
Q28572297 | Affinity purification of mammalian RNA polymerase I. Identification of an associated kinase |
Q24530608 | An RNA polymerase II complex containing all essential initiation factors binds to the activation domain of PAR leucine zipper transcription factor thyroid embryonic factor |
Q40018593 | An activation domain of the helix-loop-helix transcription factor E2A shows cell type preference in vivo in microinjected zebra fish embryos |
Q27938223 | An activator target in the RNA polymerase II holoenzyme |
Q24649275 | An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae |
Q78101732 | An interaction between the N-terminal region and the core domain of yeast TFIIB promotes the formation of TATA-binding protein-TFIIB-DNA complexes |
Q27939835 | An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae. |
Q73094158 | Analysis by atomic force microscopy of Med8 binding to cis-acting regulatory elements of the SUC2 and HXK2 genes of saccharomyces cerevisiae |
Q27929743 | Artificial recruitment of certain Mediator components affects requirement of basal transcription factor IIE. |
Q28236002 | Association of Cdk-activating kinase subunits with transcription factor TFIIH |
Q28304889 | Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes |
Q24675704 | BRCA1 is a component of the RNA polymerase II holoenzyme |
Q42484764 | Basal promoter elements as a selective determinant of transcriptional activator function |
Q29614681 | Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme |
Q24609153 | Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53 |
Q33635743 | Biochemistry meets genetics in the holoenzyme |
Q74380467 | Broad requirement for the mediator subunit RGR-1 for transcription in the Caenorhabditis elegans embryo |
Q24315725 | CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription |
Q27935522 | Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme |
Q74342700 | Characterization of NOT5 that encodes a new component of the Not protein complex |
Q58130306 | Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding Protein |
Q24550927 | Characterization of mediator complexes from HeLa cell nuclear extract |
Q27930708 | Characterization of the basal inhibitor of class II transcription NC2 from Saccharomyces cerevisiae |
Q34601114 | Characterization of the interaction between the acidic activation domain of VP16 and the RNA polymerase II initiation factor TFIIB |
Q42444028 | Chicken vigilin gene: a distinctive pattern of hypersensitive sites is characteristic for its transcriptional activity. |
Q34064159 | Chromatin-remodeling complexes involved in gene activation by the glucocorticoid receptor |
Q41477035 | Common themes in the function of transcription and splicing enhancers |
Q36035094 | Considerations of transcriptional control mechanisms: do TFIID-core promoter complexes recapitulate nucleosome-like functions? |
Q40970406 | Contacts in context: promoter specificity and macromolecular interactions in transcription |
Q40999474 | Control of transcription by steroid hormones |
Q33671418 | Cooperative assembly of RNA polymerase II transcription complexes |
Q71841189 | Core promoter elements are essential as selective determinants for function of the yeast transcription factor GAL11 |
Q42435364 | Critical role of the second stirrup region of the TATA-binding protein for transcriptional activation both in yeast and human |
Q74263600 | Cyclin-dependent kinase inhibitor p16INK4A inhibits phosphorylation of RNA polymerase II by general transcription factor TFIIH |
Q27939285 | Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast |
Q60073666 | Cyclins in initiation |
Q39575245 | DA-complex assembly activity required for VP16C transcriptional activation |
Q43749179 | DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates |
Q33886575 | Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation |
Q39539576 | Differences in determinants required for complex formation and transactivation in related VP16 proteins |
Q28207943 | Direct interaction between the subunit RAP30 of transcription factor IIF (TFIIF) and RNA polymerase subunit 5, which contributes to the association between TFIIF and RNA polymerase II |
Q27930411 | Direct interaction of RNA polymerase II and mediator required for transcription in vivo. |
Q28115255 | Direct interaction of TFIIB and the IE protein of equine herpesvirus 1 is required for maximal trans-activation function |
Q28131632 | Dissecting the regulatory circuitry of a eukaryotic genome |
Q34179615 | Dissection of transcription factor TFIIF functional domains required for initiation and elongation |
Q27939905 | Dissociable Rpb4-Rpb7 subassembly of rna polymerase II binds to single-strand nucleic acid and mediates a post-recruitment step in transcription initiation. |
Q41076983 | Distinct activated and non-activated RNA polymerase II complexes in yeast |
Q28209264 | Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme |
Q37380380 | Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. |
Q33969120 | Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes |
Q33967777 | Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters |
Q35910114 | Emerging Views on the CTD Code |
Q33361712 | Epigenomics and bolting tolerance in sugar beet genotypes |
Q33970848 | Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes |
Q36178456 | Evidence for a mediator cycle at the initiation of transcription. |
Q28216498 | Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man |
Q30700508 | Evidence that TAF-TATA box-binding protein interactions are required for activated transcription in mammalian cells |
Q27934996 | Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo |
Q34594401 | Experimentally determined weight matrix definitions of the initiator and TBP binding site elements of promoters |
Q36623298 | Extensive purification of a putative RNA polymerase I holoenzyme from plants that accurately initiates rRNA gene transcription in vitro |
Q22003918 | FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO |
Q24546284 | Factors associated with the mammalian RNA polymerase II holoenzyme |
Q24554477 | Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex |
Q27937030 | Fluorescence-based analyses of the effects of full-length recombinant TAF130p on the interaction of TATA box-binding protein with TATA box DNA. |
Q58696257 | Functional analysis of the Ume3p/ Srb11p-RNA polymerase II holoenzyme interaction |
Q52668783 | Functional and physical interactions within the middle domain of the yeast mediator. |
Q27939623 | Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo |
Q27935993 | Functional connections between mediator components and general transcription factors of Saccharomyces cerevisiae |
Q36421299 | Functional conservation of the glutamine-rich domains of yeast Gal11 and human SRC-1 in the transactivation of glucocorticoid receptor Tau 1 in Saccharomyces cerevisiae |
Q42453747 | Functional correlation among Gal11, transcription factor (TF) IIE, and TFIIH in Saccharomyces cerevisiae. Gal11 and TFIIE cooperatively enhance TFIIH-mediated phosphorylation of RNA polymerase II carboxyl-terminal domain sequences |
Q34602774 | Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae |
Q28143389 | Functional interaction of general transcription initiation factor TFIIE with general chromatin factor SPT16/CDC68 |
Q27935484 | Functional interactions within yeast mediator and evidence of differential subunit modifications |
Q91828974 | Functional interplay between Mediator and RNA polymerase II in Rad2/XPG loading to the chromatin |
Q36412489 | Functional metabolomics as a tool to analyze Mediator function and structure in plants |
Q39574441 | Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional corepressor Ssn6-Tup1. |
Q40793485 | Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors. |
Q24533173 | Functional studies of the carboxy-terminal repeat domain of Drosophila RNA polymerase II in vivo |
Q34309986 | GAL4 interacts with TATA-binding protein and coactivators |
Q41675693 | Gene regulation by the yeast Ssn6-Tup1 corepressor |
Q24561963 | General requirement for RNA polymerase II holoenzymes in vivo |
Q34610050 | Genetic analysis of the role of Pol II holoenzyme components in repression by the Cyc8-Tup1 corepressor in yeast |
Q40056449 | Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae. |
Q35036891 | Genome-wide computational prediction and analysis of core promoter elements across plant monocots and dicots |
Q41100105 | Global steps during initiation by RNA polymerase II. |
Q34524536 | Gradual phosphorylation regulates PC4 coactivator function |
Q40015882 | HPR1 encodes a global positive regulator of transcription in Saccharomyces cerevisiae |
Q51687001 | HSI2 Repressor Recruits MED13 and HDA6 to Down-Regulate Seed Maturation Gene Expression Directly During Arabidopsis Early Seedling Growth. |
Q43872500 | Head module control of mediator interactions |
Q39631335 | Heat shock factor increases the reinitiation rate from potentiated chromatin templates. |
Q45764450 | Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5. |
Q33812313 | Herpes simplex virus type 1 ICP4 promotes transcription preinitiation complex formation by enhancing the binding of TFIID to DNA |
Q24647364 | Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation |
Q33957262 | Histone acetyltransferase and protein kinase activities copurify with a putative Xenopus RNA polymerase I holoenzyme self-sufficient for promoter-dependent transcription |
Q77652527 | Histone-like TAFs are essential for transcription in vivo |
Q27934566 | Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme. |
Q24310197 | Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation |
Q24324051 | Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors |
Q35661538 | Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors |
Q24310867 | Human mediator subunit MED26 functions as a docking site for transcription elongation factors |
Q48038615 | Identification and analysis of homologues of Saccharomyces cerevisiae Spt3 suggest conserved functional domains |
Q33958879 | Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae |
Q28587897 | Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation |
Q46042839 | Identification of Rox3 as a component of mediator and RNA polymerase II holoenzyme |
Q41296506 | Identification of a Transactivation Function in the Progesterone Receptor That Interacts with the TAFII110 Subunit of the TFIID Complex |
Q24651940 | Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex |
Q22253992 | Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb |
Q35190927 | Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition |
Q33965153 | Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae |
Q52566722 | Identification of highly conserved amino-terminal segments of dTAFII230 and yTAFII145 that are functionally interchangeable for inhibiting TBP-DNA interactions in vitro and in promoting yeast cell growth in vivo. |
Q27940073 | Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae |
Q58322274 | Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome |
Q27931755 | Identification of the gene (SSU71/TFG1) encoding the largest subunit of transcription factor TFIIF as a suppressor of a TFIIB mutation in Saccharomyces cerevisiae |
Q40019304 | Identifying a species-specific region of yeast TF11B in vivo |
Q22009365 | Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators |
Q22008534 | Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes |
Q71747838 | Immunoaffinity purification of RNA polymerase II and transcription factors using polyol-responsive monoclonal antibodies |
Q74326166 | Immunoaffinity purification of the human multisubunit transcription factor IIH |
Q27938987 | Impaired core promoter recognition caused by novel yeast TAF145 mutations can be restored by creating a canonical TATA element within the promoter region of the TUB2 gene |
Q42264268 | Improving Saccharomyces cerevisiae ethanol production and tolerance via RNA polymerase II subunit Rpb7. |
Q24551113 | In vivo requirement of activator-specific binding targets of mediator |
Q28207045 | Independent recruitment in vivo by Gal4 of two complexes required for transcription |
Q44991848 | Interaction between acidic transcriptional activation domains of herpes simplex virus activator protein VP16 and transcriptional initiation factor IID. |
Q41791540 | Interaction of PC4 with melted DNA inhibits transcription |
Q22254261 | Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes |
Q27938465 | Interaction of a transcriptional repressor with the RNA polymerase II holoenzyme plays a crucial role in repression |
Q28249621 | Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators |
Q24654156 | Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF |
Q24313335 | Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor |
Q24301521 | Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5-mediating protein (RMP) |
Q42137229 | Interactions between DNA, transcriptional regulator Dreb2a and the Med25 mediator subunit from Arabidopsis thaliana involve conformational changes |
Q33775117 | Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme |
Q27935508 | Isolation and characterization of TAF25, an essential yeast gene that encodes an RNA polymerase II-specific TATA-binding protein-associated factor |
Q22008025 | Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation |
Q28586142 | Isolation of mouse TFIID and functional characterization of TBP and TFIID in mediating estrogen receptor and chromatin transcription |
Q38929299 | Kin28 regulates the transient association of Mediator with core promoters |
Q42058280 | Kinase activity and phosphorylation of the largest subunit of TFIIF transcription factor |
Q84534876 | Knockdown of NtMed8, a Med8-like gene, causes abnormal development of vegetative and floral organs in tobacco (Nicotiana tabacum L.). |
Q34318190 | MC EMiNEM maps the interaction landscape of the Mediator |
Q24554446 | MCM proteins are associated with RNA polymerase II holoenzyme |
Q37484442 | MED16 and MED23 of Mediator are coactivators of lipopolysaccharide- and heat-shock-induced transcriptional activators |
Q40020073 | Mad proteins contain a dominant transcription repression domain. |
Q38077643 | Mechanisms of Mediator complex action in transcriptional activation. |
Q34806650 | Mechanisms of basal and kinase-inducible transcription activation by CREB. |
Q33892757 | Mechanisms of gene regulation by vitamin D(3) receptor: a network of coactivator interactions. |
Q41066911 | Mechanisms of transcription complex assembly |
Q41441677 | Mechanisms of transcriptional activation: differences and similarities between yeast, Drosophila, and man. |
Q41439676 | Mechanisms of transcriptional regulation and neural gene expression |
Q27933388 | Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes |
Q41627698 | Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly. |
Q47383454 | Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system. |
Q26800203 | Mediator kinase module and human tumorigenesis |
Q34790743 | Mediator protein mutations that selectively abolish activated transcription |
Q42508865 | Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock |
Q33947315 | Mitotic recombination in yeast: elements controlling its incidence |
Q27934831 | Molecular characterization of Saccharomyces cerevisiae TFIID. |
Q39528206 | Molecular genetic dissection of TAF25, an essential yeast gene encoding a subunit shared by TFIID and SAGA multiprotein transcription factors |
Q29620260 | Molecular genetics of the RNA polymerase II general transcriptional machinery |
Q34597589 | Molecular weight determination of plasmid DNA using electrospray ionization mass spectrometry |
Q22122454 | Multi-protein complexes in eukaryotic gene transcription |
Q33957679 | Multiple layers of cooperativity regulate enhanceosome-responsive RNA polymerase II transcription complex assembly |
Q28576482 | Multiple mammalian proteasomal ATPases, but not proteasome itself, are associated with TATA-binding protein and a novel transcriptional activator, TIP120 |
Q36044214 | Mutational studies of yeast transcription factor IIB in vivo reveal a functional surface important for gene activation |
Q42494682 | Mutations in the TATA-binding protein, affecting transcriptional activation, show synthetic lethality with the TAF145 gene lacking the TAF N-terminal domain in Saccharomyces cerevisiae |
Q42524559 | Mutations in the yeast SRB2 general transcription factor suppress hpr1-induced recombination and show defects in DNA repair |
Q28282085 | NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription |
Q71533736 | New chemistry for the study of multiprotein complexes: the six-histidine tag as a receptor for a protein crosslinking reagent |
Q40731209 | Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells |
Q33757699 | Novel critical role of a human Mediator complex for basal RNA polymerase II transcription |
Q28074780 | Nucleosome distortion as a possible mechanism of transcription activation domain function |
Q46552388 | Nucleotide requirements for activated RNA polymerase II open complex formation in vitro |
Q50457007 | PHYTOCHROME AND FLOWERING TIME1/MEDIATOR25 Regulates Lateral Root Formation via Auxin Signaling in Arabidopsis |
Q36557179 | Paf1p, an RNA polymerase II-associated factor in Saccharomyces cerevisiae, may have both positive and negative roles in transcription |
Q36788358 | Partial truncation of the yeast RNA polymerase II carboxyl-terminal domain preferentially reduces expression of glycolytic genes |
Q71000825 | Phosphorylation dependence of the initiation of productive transcription of Balbiani ring 2 genes in living cells |
Q34093159 | Phosphorylation in transcription: the CTD and more |
Q44117541 | Physical association of the APIS complex and general transcription factors |
Q33367783 | Pieces of the puzzle: assembling the preinitiation complex of Pol II. |
Q48362347 | Plant-plant interactions influence developmental phase transitions, grain productivity and root system architecture in Arabidopsis via auxin and PFT1/MED25 signalling. |
Q36332739 | Polycomb repressive complex 1 (PRC1) disassembles RNA polymerase II preinitiation complexes. |
Q24548316 | Positive and negative TAF(II) functions that suggest a dynamic TFIID structure and elicit synergy with traps in activator-induced transcription |
Q47829612 | Preinitation complex assembly: potentially a bumpy path. |
Q44560693 | Preponderance of free mediator in the yeast Saccharomyces cerevisiae |
Q36573810 | Promoter activity of Tat at steps subsequent to TATA-binding protein recruitment |
Q41100064 | Promoters and basal transcription machinery in eubacteria and eukaryotes: concepts, definitions, and analogies |
Q41032848 | Properties of PC4 and an RNA polymerase II complex in directing activated and basal transcription in vitro |
Q45970861 | Protease footprinting analysis of ternary complex formation by human TFIIA. |
Q36288964 | Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking |
Q46216244 | Purification and characterization of an RNA polymerase II phosphatase from yeast |
Q75231661 | Purification and transcriptional analysis of RNA polymerase I holoenzymes from broccoli (Brassica oleracea) and frog (Xenopus laevis) |
Q41100162 | Purification of yeast RNA polymerase II holoenzymes |
Q24317228 | Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes |
Q39446590 | Quantitation of RNA polymerase II and its transcription factors in an HeLa cell: little soluble holoenzyme but significant amounts of polymerases attached to the nuclear substructure |
Q41076429 | Quantitation of putative activator-target affinities predicts transcriptional activating potentials |
Q35182494 | Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors |
Q36649506 | RAP74 induces promoter contacts by RNA polymerase II upstream and downstream of a DNA bend centered on the TATA box. |
Q22008019 | RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X protein |
Q41350631 | RNA polymerase II C-terminal domain required for enhancer-driven transcription |
Q33632354 | RNA polymerase II as a control panel for multiple coactivator complexes |
Q33905060 | RNA polymerase II carboxy-terminal domain kinases: emerging clues to their function |
Q39035964 | RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe |
Q41477041 | RNA polymerase II holoenzyme and transcriptional regulation |
Q70908581 | RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling |
Q73205344 | RNA polymerase II holoenzyme recruitment is sufficient to remodel chromatin at the yeast PHO5 promoter |
Q34067671 | RNA polymerase II holoenzymes and subcomplexes. |
Q58701536 | RNA polymerase II transcription complex assembly in nuclear extracts |
Q27933821 | RSC, an essential, abundant chromatin-remodeling complex |
Q36555479 | Recruiting TATA-binding protein to a promoter: transcriptional activation without an upstream activator |
Q34011557 | Recruitment of an RNA polymerase II complex is mediated by the constitutive activation domain in CREB, independently of CREB phosphorylation |
Q27631291 | Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain |
Q28646829 | Recycling of the general transcription factors during RNA polymerase II transcription |
Q34011585 | Region of yeast TAF 130 required for TFIID to associate with promoters |
Q54228372 | Regulation of Mammalian Ribosomal Gene Transcription by RNA Polymerase I |
Q77485523 | Regulatory targets in the RNA polymerase II holoenzyme |
Q28289887 | Requirement for TFIIH kinase activity in transcription by RNA polymerase II |
Q32036964 | Requirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcription |
Q36567515 | Retinoid X receptor:vitamin D3 receptor heterodimers promote stable preinitiation complex formation and direct 1,25-dihydroxyvitamin D3-dependent cell-free transcription |
Q36556040 | Reversal of in vitro p53 squelching by both TFIIB and TFIID |
Q33964585 | Robust mRNA transcription in chicken DT40 cells depleted of TAF(II)31 suggests both functional degeneracy and evolutionary divergence |
Q33671382 | Role of general and gene-specific cofactors in the regulation of eukaryotic transcription |
Q73947536 | Rpb4, a non-essential subunit of core RNA polymerase II of Saccharomyces cerevisiae is important for activated transcription of a subset of genes |
Q27929864 | SPN1, a conserved gene identified by suppression of a postrecruitment-defective yeast TATA-binding protein mutant |
Q27933314 | SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II |
Q27933054 | SUG1, a component of the 26 S proteasome, is an ATPase stimulated by specific RNAs |
Q42439710 | Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription |
Q34472506 | Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module |
Q58422699 | Simplifying the complex |
Q37228807 | Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity |
Q36710832 | Sir2 silences gene transcription by targeting the transition between RNA polymerase II initiation and elongation |
Q37073125 | Site-specific Srb10-dependent phosphorylation of the yeast Mediator subunit Med2 regulates gene expression from the 2-microm plasmid |
Q74754870 | Small-molecule-based strategies for controlling gene expression |
Q41980416 | Spe3, which encodes spermidine synthase, is required for full repression through NRE(DIT) in Saccharomyces cerevisiae |
Q90471342 | Specific functions for Mediator complex subunits from different modules in the transcriptional response of Arabidopsis thaliana to abiotic stress |
Q33903270 | Specific interaction of TAFII105 with OCA-B is involved in activation of octamer-dependent transcription |
Q24540125 | Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD |
Q36254517 | Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA |
Q27933861 | Srb/mediator proteins interact functionally and physically with transcriptional repressor Sfl1. |
Q36724531 | Strong transcriptional activators isolated from viral DNA by the 'activator trap', a novel selection system in mammalian cells |
Q42041363 | Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator |
Q35669885 | Structure and function of the TFIID complex |
Q27666838 | Structure-function analysis of hRPC62 provides insights into RNA polymerase III transcription initiation |
Q24304075 | Subcellular localization of RPB5-mediating protein and its putative functional partner |
Q24633293 | Subunit architecture of general transcription factor TFIIH |
Q41932256 | Suppression analysis reveals a functional difference between the serines in positions two and five in the consensus sequence of the C-terminal domain of yeast RNA polymerase II |
Q36300660 | Synergistic and promoter-selective activation of transcription by recruitment of transcription factors TFIID and TFIIB. |
Q41064463 | Synergistic enhancement of both initiation and elongation by acidic transcription activation domains. |
Q27938743 | Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo |
Q42459088 | TAFII-independent activation mediated by human TBP in the presence of the positive cofactor PC4 |
Q28581872 | TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism |
Q33962132 | TATA-binding protein mutants that increase transcription from enhancerless and repressed promoters in vivo |
Q40791931 | TATA-binding protein-associated factors enhance the recruitment of RNA polymerase II by transcriptional activators |
Q37695809 | TBP mutants defective in activated transcription in vivo. |
Q33832058 | TBP-associated factors (TAFIIs): multiple, selective transcriptional mediators in common complexes |
Q42522148 | TBP-associated factors are not generally required for transcriptional activation in yeast |
Q34718574 | TFIIA plays a role in the response to oxidative stress |
Q34654319 | TFIIB and the regulation of transcription by RNA polymerase II. |
Q40018632 | TFIIB-directed transcriptional activation by the orphan nuclear receptor hepatocyte nuclear factor 4. |
Q35207267 | TFIID-specific yeast TAF40 is essential for the majority of RNA polymerase II-mediated transcription in vivo |
Q28116305 | Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription |
Q27934702 | Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases |
Q33753938 | Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions |
Q28570708 | The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins |
Q52119435 | The C-terminal domain of the largest subunit of RNA polymerase II is required for stationary phase entry and functionally interacts with the Ras/PKA signaling pathway. |
Q33887586 | The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex |
Q33772811 | The Gcn4p activation domain interacts specifically in vitro with RNA polymerase II holoenzyme, TFIID, and the Adap-Gcn5p coactivator complex |
Q48874029 | The MED-7 transcriptional mediator encoded by let-49 is required for gonad and germ cell development in Caenorhabditis elegans |
Q24609120 | The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain |
Q27937894 | The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression. |
Q28299679 | The Mediator complex and transcription regulation |
Q35131077 | The Mediator complex of Caenorhabditis elegans: insights into the developmental and physiological roles of a conserved transcriptional coregulator |
Q36119053 | The Mediator complex subunit 8 regulates organ size in Arabidopsis thaliana |
Q28623816 | The Oct-1 POU domain activates snRNA gene transcription by contacting a region in the SNAPc largest subunit that bears sequence similarities to the Oct-1 coactivator OBF-1 |
Q28623435 | The Oct-1 POU-specific domain can stimulate small nuclear RNA gene transcription by stabilizing the basal transcription complex SNAPc |
Q37671309 | The Paf1 complex: platform or player in RNA polymerase II transcription? |
Q29622942 | The RNA polymerase II holoenzyme and its implications for gene regulation |
Q39721405 | The RNA polymerase II preinitiation complex formed in the presence of ATP |
Q27939572 | The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo. |
Q24298533 | The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis |
Q24336424 | The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor |
Q33794695 | The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo |
Q28248516 | The ancient regulatory-protein family of WD-repeat proteins |
Q78680279 | The co-activator p300 associates physically with and can mediate the action of the distal enhancer of the FGF-4 gene |
Q24598984 | The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation |
Q41756430 | The estrogen receptor gene: promoter organization and expression |
Q35805081 | The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways? |
Q28619324 | The general transcription factors IIA, IIB, IIF, and IIE are required for RNA polymerase II transcription from the human U1 small nuclear RNA promoter |
Q24600925 | The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain |
Q27930236 | The histone H3-like TAF is broadly required for transcription in yeast |
Q22001483 | The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex |
Q28304955 | The mammalian Mediator complex |
Q35669882 | The mediator complex |
Q43293809 | The mediator complex subunit PFT1 is a key regulator of jasmonate-dependent defense in Arabidopsis |
Q46371249 | The photoactivated cross-linking of recombinant C-terminal domain to proteins in a HeLa cell transcription extract that comigrate with transcription factors IIE and IIF. |
Q35887891 | The product of the adenovirus intermediate gene IX is a transcriptional activator. |
Q25255839 | The proteasomal ATPase complex is required for stress-induced transcription in yeast |
Q39681879 | The role of TFIIB-RNA polymerase II interaction in start site selection in yeast cells |
Q40672423 | The role of activators in assembly of RNA polymerase II transcription complexes |
Q41557723 | The role of chromatin in transcriptional regulation. |
Q27932113 | The rye mutants identify a role for Ssn/Srb proteins of the RNA polymerase II holoenzyme during stationary phase entry in Saccharomyces cerevisiae |
Q24652864 | The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids |
Q27934704 | The yeast GAL11 protein binds to the transcription factor IIE through GAL11 regions essential for its in vivo function |
Q42966231 | The yeast HRS1 gene encodes a polyglutamine-rich nuclear protein required for spontaneous and hpr1-induced deletions between direct repeats. |
Q27932742 | The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex |
Q42629947 | Three classes of mammalian transcription activation domain stimulate transcription in Schizosaccharomyces pombe |
Q24532893 | Three transitions in the RNA polymerase II transcription complex during initiation |
Q41361209 | Topological localization of the carboxyl-terminal domain of RNA polymerase II in the initiation complex |
Q48174606 | Toward understanding of the mechanisms of Mediator function in vivo: Focus on the preinitiation complex assembly |
Q74033390 | Towards a minimal motif for artificial transcriptional activators |
Q38348614 | Transcription Activation by a PNA-Peptide Chimera in a Mammalian Cell Extract |
Q39716921 | Transcription activation by GC-boxes: evaluation of kinetic and equilibrium contributions |
Q47858026 | Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs |
Q41046368 | Transcription factor AP-1, and the role of Fra-2. |
Q45730477 | Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr. |
Q41442509 | Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes |
Q29618752 | Transcription regulation and animal diversity |
Q50057687 | Transcription regulation by the Mediator complex |
Q37353465 | Transcription syndromes and the role of RNA polymerase II general transcription factors in human disease |
Q41044026 | Transcription: basal factors and activation. |
Q73159428 | Transcription: why are TAFs essential? |
Q40494477 | Transcriptional Activation: Tuning-up transcription |
Q36573748 | Transcriptional activation by TFIIB mutants that are severely impaired in interaction with promoter DNA and acidic activation domains |
Q35058398 | Transcriptional activation by artificial recruitment in yeast is influenced by promoter architecture and downstream sequences |
Q29615048 | Transcriptional activation by recruitment |
Q40935476 | Transcriptional activation. A holistic view of the complex. |
Q28486904 | Transcriptional activators control splicing and 3'-end cleavage levels |
Q40951549 | Transcriptional coactivators in yeast and beyond |
Q24554483 | Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent manner |
Q24530710 | Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes |
Q36558597 | Transcriptional corepression in vitro: a Mot1p-associated form of TATA-binding protein is required for repression by Leu3p |
Q73019085 | Transcriptional enhancement by acidic activators |
Q33904338 | Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells |
Q35964659 | Transcriptional regulation: contending with complexity |
Q39870080 | Transcriptional trans activation by human immunodeficiency virus type 1 Tat requires specific coactivators that are not basal factors. |
Q27930891 | Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF. |
Q44341024 | Two forms of RNA polymerase II holoenzyme display different abundance during the cell cycle. |
Q28507179 | Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice |
Q41056225 | Ultraviolet radiation-induced ubiquitination and proteasomal degradation of the large subunit of RNA polymerase II. Implications for transcription-coupled DNA repair |
Q42966234 | Underproduction of the largest subunit of RNA polymerase II causes temperature sensitivity, slow growth, and inositol auxotrophy in Saccharomyces cerevisiae |
Q40423733 | Unraveling the mechanism of a potent transcriptional activator |
Q92684595 | Unveiling the gene regulatory landscape in diseases through the identification of DNase I-hypersensitive sites |
Q27929931 | Vanishingly low levels of Ess1 prolyl-isomerase activity are sufficient for growth in Saccharomyces cerevisiae |
Q40395601 | Variable pause positions of RNA polymerase II lie proximal to the c-myc promoter irrespective of transcriptional activity. |
Q34613177 | Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8 |
Q38307266 | Virtually unidirectional binding of TBP to the AdMLP TATA box within the quaternary complex with TFIIA and TFIIB. |
Q42497133 | Yeast GAL11 protein stimulates basal transcription in a gene-specific manner by a mechanism distinct from that by DNA-bound activators |
Q27934583 | Yeast Gal11 and transcription factor IIE function through a common pathway in transcriptional regulation |
Q24563103 | Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4 |
Q29622932 | Yeast carbon catabolite repression |
Q33739221 | Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. |
Q33971943 | Yeast two-hybrid systems and protein interaction mapping projects for yeast and worm |
Q73728723 | [Activation of transcription in eukaryotic cells: interactions between transcription factors and components of the basal transcriptional mechanism] |
Q24602633 | mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain |
Q77652532 | yTAFII61 has a general role in RNA polymerase II transcription and is required by Gcn4p to recruit the SAGA coactivator complex |
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