Transcriptional trans activation by human immunodeficiency virus type 1 Tat requires specific coactivators that are not basal factors.

scientific article published on May 1995

Transcriptional trans activation by human immunodeficiency virus type 1 Tat requires specific coactivators that are not basal factors. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID189011
P698PubMed publication ID7707538

P50authorCarlos SuñéQ55143545
P2093author name stringGarcía-Blanco MA
P2860cites workA cDNA for a protein that interacts with the human immunodeficiency virus Tat transactivatorQ24338540
Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat proteinQ24561778
Composition of transcription factor B-TFIIDQ24564149
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53Q24609153
Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral Tat protein and cellular transcription factor Sp1Q24644981
Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeatQ24655684
In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factorQ24655901
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferaseQ27860571
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
New human gene encoding a positive modulator of HIV Tat-mediated transactivationQ28187359
Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another proteinQ28247468
Direct interaction of human TFIID with the HIV-1 transactivator tatQ28250314
A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activatorQ40650101
Tat and the HIV-1 promoterQ40835492
Functional and biochemical interaction of the HTLV-I Tax1 transactivator with TBP.Q40874297
Does HIV-1 Tat induce a change in viral initiation rights?Q40905875
Analysis of Tat transactivation of human immunodeficiency virus transcription in vitro.Q41079020
HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structureQ41234955
TAR-independent activation of the HIV-1 LTR: evidence that tat requires specific regions of the promoterQ41724573
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complexQ42468497
HIV-1 Tat Overcomes Inefficient Transcriptional Elongation in VitroQ42483631
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activatorsQ42491732
Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB.Q42502083
Specific interaction of the human immunodeficiency virus Tat proteins with a cellular protein kinase.Q43447901
HIV-1 tat trans-activation requires the loop sequence within tar.Q44349676
Mutational analysis of HIV-1 Tat minimal domain peptides: identification of trans-dominant mutants that suppress HIV-LTR-driven gene expressionQ44389543
Fragments of the HIV-1 Tat protein specifically bind TAR RNA.Q45148606
Blocking of Tat-dependent HIV-1 RNA modification by an inhibitor of RNA polymerase II processivityQ45227677
A nuclear translational block imposed by the HIV-1 U3 region is relieved by the Tat-TAR interactionQ45256281
Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator proteinQ45830211
Trans-activation of human immunodeficiency virus occurs via a bimodal mechanismQ45830933
Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genesQ45831871
Does the human immunodeficiency virus Tat trans-activator contain a discrete activation domain?Q45850138
Factors (TAFs) required for activated transcription interact with TATA box-binding protein conserved core domain.Q45934754
Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factorQ46050449
Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeatQ46674379
Separation and characterization of factors mediating accurate transcription by RNA polymerase II.Q47956947
Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIIDQ59070657
Human chromosome 12 is required for elevated HIV-1 expression in human-hamster hybrid cellsQ64129425
The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat functionQ67782274
An improved procedure for the purification of protein fused with glutathione S-transferaseQ67979721
Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cellsQ68504983
A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activationQ68583028
Mechanism of action of an acidic transcriptional activator in vitroQ70113517
HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factorsQ28298100
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activationQ28303864
Characterization of cDNAs encoding the polypyrimidine tract-binding proteinQ28609636
An RNA polymerase II holoenzyme responsive to activatorsQ29620210
Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivatorsQ29620376
HIV-1 Tat protein increases transcriptional initiation and stabilizes elongationQ29620799
HIV-1 Tat protein trans-activates transcription in vitroQ30411837
Fasciola hepatica: molecular cloning, nucleotide sequence, and expression of a gene encoding a polypeptide homologous to a Schistosoma mansoni fatty acid-binding proteinQ33215947
Identification and characterization of a HeLa nuclear protein that specifically binds to the trans-activation-response (TAR) element of human immunodeficiency virusQ33575002
A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeatQ33662926
Inhibition of human immunodeficiency virus type 1 Tat activity by coexpression of heterologous trans activatorsQ33930741
Contribution of the TATA motif to Tat-mediated transcriptional activation of human immunodeficiency virus gene expressionQ33936851
Trans-activation by HIV-1 Tat via a heterologous RNA binding proteinQ34156002
Specific binding of a HeLa cell nuclear protein to RNA sequences in the human immunodeficiency virus transactivating regionQ34284937
Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitroQ34303073
Two distinct nuclear transcription factors recognize loop and bulge residues of the HIV-1 TAR RNA hairpinQ34631467
Activation of class II gene transcription by regulatory factors is potentiated by a novel activityQ34855093
tat regulates binding of the human immunodeficiency virus trans-activating region RNA loop-binding protein TRP-185.Q34975992
Mechanism of action of regulatory proteins encoded by complex retrovirusesQ35403061
HIV-1 Tat protein promotes formation of more-processive elongation complexesQ35937536
Human immunodeficiency virus type 1 transactivator protein, tat, stimulates transcriptional read-through of distal terminator sequences in vitroQ36398874
Human chromosome 12 encodes a species-specific factor which increases human immunodeficiency virus type 1 tat-mediated trans activation in rodent cellsQ36783325
Structural requirements for trans activation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by tat: importance of base pairing, loop sequence, and bulges in the tat-responsive sequence.Q36802812
trans activation of human immunodeficiency virus type 1 is sequence specific for both the single-stranded bulge and loop of the trans-acting-responsive hairpin: a quantitative analysis.Q36832567
Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID.Q36846156
The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongationQ37506941
Isolation of a cellular protein that binds to the human immunodeficiency virus Tat protein and can potentiate transactivation of the viral promoterQ37603547
The human immunodeficiency virus type 1 long terminal repeat specifies two different transcription complexes, only one of which is regulated by TatQ38320497
The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequenceQ38324797
Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoterQ38325574
Unusual structure of the human immunodeficiency virus type 1 trans-activation response elementQ38330641
Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulationQ38345116
Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function.Q40045693
ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB.Q40046433
The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID.Q40066427
Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeatQ40129795
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)3098-3107
P577publication date1995-05-01
P1433published inJournal of VirologyQ1251128
P1476titleTranscriptional trans activation by human immunodeficiency virus type 1 Tat requires specific coactivators that are not basal factors
P478volume69

Reverse relations

cites work (P2860)
Q33840754A re-examination of global suppression of RNA interference by HIV-1.
Q39717672A small circular TAR RNA decoy specifically inhibits Tat-activated HIV-1 transcription
Q24682560Activation of transcription factor NF-kappaB by the Tat protein of human immunodeficiency virus type 1
Q24315725CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription
Q24806175COUP-TF interacting protein 2 represses the initial phase of HIV-1 gene transcription in human microglial cells
Q28768535Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice
Q35872597Inhibition of human immunodeficiency virus type 1 and type 2 Tat function by transdominant Tat protein localized to both the nucleus and cytoplasm
Q24671522Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator
Q36724734Mutations generated in human immunodeficiency virus type 1 long terminal repeat during vertical transmission correlate with viral gene expression
Q24523183PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo
Q33769035Regulation of HIV-1 transcription
Q33684254Regulation of P-glycoprotein by human immunodeficiency virus-1 in primary cultures of human fetal astrocytes
Q24674098Role for Fox-1/Fox-2 in mediating the neuronal pathway of calcitonin/calcitonin gene-related peptide alternative RNA processing
Q39872155Sp1 transcription factor is required for in vitro basal and Tat-activated transcription from the human immunodeficiency virus type 1 long terminal repeat
Q24537527Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences
Q42848859TAR RNA decoys inhibit tat-activated HIV-1 transcription after preinitiation complex formation
Q24605302Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II
Q39069527Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication.

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