Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat

scientific article published on March 1988

Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID253619
P698PubMed publication ID2828663

P2093author name stringCullen BR
Hauber J
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
2 New M13 vectors for cloningQ27861042
Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDSQ28262859
Nucleotide sequence of the AIDS virus, LAVQ28286313
Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II)Q28288709
Improved Estimation of Secondary Structure in Ribonucleic AcidsQ29616525
An inducible transcription factor activates expression of human immunodeficiency virus in T cellsQ29618434
Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III.Q34161762
A second post-transcriptional trans-activator gene required for HTLV-III replicationQ34162178
HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA.Q34186306
Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear eventsQ34344850
The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeatQ34564367
Polymorphism of the 3' open reading frame of the virus associated with the acquired immune deficiency syndrome, human T-lymphotropic virus type III.Q35564616
Nudease-hypersensitive sites in the chromalin domain of the chicken lysozyme geneQ35676704
Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virusQ37412665
Interaction between two transcriptional control sequences required for tumor-antigen-mediated simian virus 40 late gene expressionQ37553332
Adenovirus promoters and E1A transactivationQ39507235
Regulation of inducible and tissue-specific gene expressionQ39656942
DNAase I-hypersensitive sites of chromatinQ40081637
ChromatinQ40130938
Expression of the art/trs protein of HIV and study of its role in viral envelope synthesisQ41886681
Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I.Q43858457
Human interleukin 2.Q43867352
The trans-activator gene of the human T cell lymphotropic virus type III is required for replicationQ44579665
Demonstration of virus-specific transcriptional activator(s) in cells infected with HTLV-III by an in vitro cell-free systemQ45029117
Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator proteinQ45830211
Trans-activation of human immunodeficiency virus occurs via a bimodal mechanismQ45830933
Expression and characterization of the trans-activator of HTLV-III/LAV virusQ45831293
Complete nucleotide sequences of functional clones of the AIDS virusQ45834378
Regulation of AIDS virus expressionQ45836093
Trans-activator gene of human T-lymphotropic virus type III (HTLV-III).Q45838520
Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1.Q48365300
Identification of a cellular transcription factor involved in E1A trans-activationQ48366187
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitroQ48375884
Nucleotide sequence and expression of an AIDS-associated retrovirus (ARV-2).Q48381924
Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region.Q54739833
Alternative sets of DNase I-hypersensitive sites characterize the various functional states of the chicken lysozyme geneQ59092573
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmutational analysisQ1955810
P304page(s)673-679
P577publication date1988-03-01
P1433published inJournal of VirologyQ1251128
P1476titleMutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat
P478volume62

Reverse relations

cites work (P2860)
Q24684723A Tat-induced auto-up-regulatory loop for superactivation of the human immunodeficiency virus type 1 promoter
Q35833883A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses
Q64378953A region of basic amino-acid cluster in HIV-1 Tat protein is essential for trans-acting activity and nucleolar localization
Q39717672A small circular TAR RNA decoy specifically inhibits Tat-activated HIV-1 transcription
Q33662926A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat
Q34306796Activity of synthetic peptides from the Tat protein of human immunodeficiency virus type 1
Q40060891An adenosine at position 27 in the human immunodeficiency virus type 1 trans-activation response element is not critical for transcriptional or translational activation by Tat
Q41079020Analysis of Tat transactivation of human immunodeficiency virus transcription in vitro.
Q36831828Analysis of regulatory elements of the equine infectious anemia virus and caprine arthritis-encephalitis virus long terminal repeats
Q36828521Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation
Q33834125Bioassay for trans-activation using purified human immunodeficiency virus tat-encoded protein: trans-activation requires mRNA synthesis
Q36696760Bovine immunodeficiency-like virus encodes factors which trans activate the long terminal repeat
Q33795939Cell cycle-regulated transcription by the human immunodeficiency virus type 1 Tat transactivator
Q28342742Cell type-specific anti-human immunodeficiency virus type 1 activity of the transactivation inhibitor Ro5-3335
Q41576182Characterization of the inducer of short transcripts, a human immunodeficiency virus type 1 transcriptional element that activates the synthesis of short RNAs.
Q34160290Click dimers to target HIV TAR RNA conformation
Q24317451Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
Q34671913Comparison of SIV and HIV-1 genomic RNA structures reveals impact of sequence evolution on conserved and non-conserved structural motifs
Q40454547Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape.
Q33936851Contribution of the TATA motif to Tat-mediated transcriptional activation of human immunodeficiency virus gene expression
Q36798014Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein
Q36807977Cytomegalovirus activates transcription directed by the long terminal repeat of human immunodeficiency virus type 1.
Q35792991Detailed mutational analysis of TAR RNA: critical spacing between the bulge and loop recognition domains
Q40041542Differential growth kinetics are exhibited by human immunodeficiency virus type 1 TAR mutants
Q33815010Direct evidence for translational regulation by leader RNA and Tat protein of human immunodeficiency virus type 1.
Q33835531Effects of homology length in the repeat region on minus-strand DNA transfer and retroviral replication
Q40041905Effects of human chromosome 12 on interactions between Tat and TAR of human immunodeficiency virus type 1.
Q35835407Efficient trans-activation by the HIV-2 Tat protein requires a duplicated TAR RNA structure
Q36793376Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs
Q36687332Evidence that a sequence similar to TAR is important for induction of the JC virus late promoter by human immunodeficiency virus type 1 Tat
Q37633114Evolution of a disrupted TAR RNA hairpin structure in the HIV-1 virus.
Q36831988Functional analysis of the Tat trans activator of human immunodeficiency virus type 2.
Q40116360Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region.
Q36873530Functional comparison of transactivation by simian immunodeficiency virus from rhesus macaques and human immunodeficiency virus type 1.
Q38346354Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat
Q24655684Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat
Q37056955Genetic regulation of human immunodeficiency virus.
Q35937536HIV-1 Tat protein promotes formation of more-processive elongation complexes
Q41234955HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure
Q40407802Human T cell transcription factor GATA-3 stimulates HIV-1 expression
Q36798955Human immunodeficiency virus Tat transactivation: induction of a tissue-specific enhancer in a nonpermissive cell line
Q38345116Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulation
Q38293063Human immunodeficiency virus type 1 TAR element revertant viruses define RNA structures required for efficient viral gene expression and replication
Q36640831Human immunodeficiency viruses containing heterologous enhancer/promoters are replication competent and exhibit different lymphocyte tropisms
Q37633631Human immunodeficiency viruses regulated by alternative trans-activators: genetic evidence for a novel non-transcriptional function of Tat in virion infectivity.
Q33575002Identification and characterization of a HeLa nuclear protein that specifically binds to the trans-activation-response (TAR) element of human immunodeficiency virus
Q34311433Identification of cellular proteins that bind to the human immunodeficiency virus type 1 trans-activation-responsive TAR element RNA
Q40066797Identification of lentivirus tat functional domains through generation of equine infectious anemia virus/human immunodeficiency virus type 1 tat gene chimeras
Q40046178Identification of transactivation-response sequences in the long terminal repeat of bovine immunodeficiency-like virus
Q35792284Identification of transcriptional suppressor proteins that bind to the negative regulatory element of the human immunodeficiency virus type 1
Q35888626Inhibition of human immunodeficiency virus replication by the herpes simplex virus virion host shutoff protein
Q33930741Inhibition of human immunodeficiency virus type 1 Tat activity by coexpression of heterologous trans activators
Q28378556Inhibition of type 1 human immunodeficiency virus replication by a tat antagonist to which the virus remains sensitive after prolonged exposure in vitro
Q24671522Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator
Q38188271Life of psi: how full-length HIV-1 RNAs become packaged genomes in the viral particles
Q35403061Mechanism of action of regulatory proteins encoded by complex retroviruses
Q39820667Molecular biology and pathogenesis of animal lentivirus infections.
Q38320613Multiple positive and negative cis-acting elements that mediate transactivation by bel1 in the long terminal repeat of human foamy virus.
Q36831514Multiple transcriptional regulatory domains in the human immunodeficiency virus type 1 long terminal repeat are involved in basal and E1A/E1B-induced promoter activity
Q36788071Multivalent Amino Sugars to Recognize Different TAR RNA Conformations.
Q24656004Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein
Q36804564Mutational analysis of the conserved cysteine-rich region of the human immunodeficiency virus type 1 Tat protein
Q36700611Mutational analysis of the equine infectious anemia virus Tat-responsive element
Q24682057Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly
Q39719048Optimal Tat-mediated activation of the HIV-1 LTR promoter requires a full-length TAR RNA hairpin
Q40043226Orientation-specific cis complementation by bulge- and loop-mutated human immunodeficiency virus type 1 TAR RNAs.
Q34523721Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.
Q40066451Premature termination and processing of human immunodeficiency virus type 1-promoted transcripts
Q47554842Production of HIV-1 vif mRNA Is Modulated by Natural Nucleotide Variations and SLSA1 RNA Structure in SA1D2prox Genomic Region
Q42735234Purification of the human immunodeficiency virus type 1 enhancer and TAR binding proteins EBP-1 and UBP-1.
Q39550188R region sequences in the long terminal repeat of a murine retrovirus specifically increase expression of unspliced RNAs.
Q39877972RNA-targeted activators, but not DNA-targeted activators, repress the synthesis of short transcripts at the human immunodeficiency virus type 1 long terminal repeat.
Q36694541Rapid activation and subsequent down-regulation of the human immunodeficiency virus type 1 promoter in the presence of Tat: possible mechanisms contributing to latency
Q33961121Recognition of HIV TAR RNA by triazole linked neomycin dimers
Q24646216Regulation of human immunodeficiency virus env expression by the rev gene product
Q24645992Role of SP1-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat
Q42457052Sequences within the R region of the long terminal repeat activate basal transcription from the HIV-1 promoter.
Q39872155Sp1 transcription factor is required for in vitro basal and Tat-activated transcription from the human immunodeficiency virus type 1 long terminal repeat
Q34284937Specific binding of a HeLa cell nuclear protein to RNA sequences in the human immunodeficiency virus transactivating region
Q36796119Structural analysis of wild-type and mutant human immunodeficiency virus type 1 Tat proteins
Q36802812Structural requirements for trans activation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by tat: importance of base pairing, loop sequence, and bulges in the tat-responsive sequence.
Q28547355Structure-Based Alignment and Consensus Secondary Structures for Three HIV-Related RNA Genomes
Q41238682TAR independent activation of the human immunodeficiency virus in phorbol ester stimulated T lymphocytes
Q24555668TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation
Q37059502Tat and Rev: positive modulators of human immunodeficiency virus gene expression
Q37594301Tat-dependent adenosine-to-inosine modification of wild-type transactivation response RNA.
Q40628737The 0.3-kb fragment containing the R-U5-5'leader sequence of Friend murine leukemia virus influences the level of protein expression from spliced mRNA.
Q36698552The Bel-1 protein of human foamy virus activates human immunodeficiency virus type 1 gene expression via a novel DNA target site
Q38317126The NF-kappa B and Sp1 motifs of the human immunodeficiency virus type 1 long terminal repeat function as novel thyroid hormone response elements
Q36831819The NF-kappa B binding sites in the human immunodeficiency virus type 1 long terminal repeat are not required for virus infectivity.
Q34180644The bend in RNA created by the trans-activation response element bulge of human immunodeficiency virus is straightened by arginine and by Tat-derived peptide
Q36649447The full-length Tat protein is required for TAR-independent, posttranscriptional trans activation of human immunodeficiency virus type 1 env gene expression.
Q40725617The genome of feline immunodeficiency virus.
Q36632734The human immunodeficiency virus type 1 Tat protein transactivates tumor necrosis factor beta gene expression through a TAR-like structure.
Q37548928The number of positively charged amino acids in the basic domain of Tat is critical for trans-activation and complex formation with TAR RNA
Q34317298The same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type 1 long terminal repeat
Q39580918The secondary structure of the R region of a murine leukemia virus is important for stimulation of long terminal repeat-driven gene expression.
Q33567142Trans-activation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells
Q40526004Transactivation of heterologous promoters by HIV-1 tat.
Q36797541Transcellular transactivation by the human immunodeficiency virus type 1 tat protein
Q35070466Transcriptional activity of the human immunodeficiency virus-1 LTR promoter in fission yeast Schizosaccharomyces pombe
Q36797785Transcriptional elongation by purified RNA polymerase II is blocked at the trans-activation-responsive region of human immunodeficiency virus type 1 in vitro
Q36828988Transcriptional initiation and postinitiation effects of murine leukemia virus long terminal repeat R-region sequences
Q34352999Transcriptional regulation of porcine endogenous retroviruses released from porcine and infected human cells by heterotrimeric protein complex NF-Y and impact of immunosuppressive drugs
Q39870080Transcriptional trans activation by human immunodeficiency virus type 1 Tat requires specific coactivators that are not basal factors.
Q36708965Translational control of retroviruses.
Q38330641Unusual structure of the human immunodeficiency virus type 1 trans-activation response element
Q33400343Yeast genetic analysis reveals the involvement of chromatin reassembly factors in repressing HIV-1 basal transcription

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