Herpes simplex virus 1 ICP4 forms complexes with TFIID and mediator in virus-infected cells

scientific article published on 30 March 2011

Herpes simplex virus 1 ICP4 forms complexes with TFIID and mediator in virus-infected cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.00385-11
P932PMC publication ID3126299
P698PubMed publication ID21450820

P2093author name stringNeal A DeLuca
Jonathan T Lester
P2860cites workPhosphorylation of the varicella-zoster virus (VZV) major transcriptional regulatory protein IE62 by the VZV open reading frame 66 protein kinaseQ43203463
TATA-binding protein and TBP-associated factors during herpes simplex virus type 1 infection: localization at viral DNA replication sitesQ45422778
Eukaryotic activators function during multiple steps of preinitiation complex assemblyQ59058665
A transcription reinitiation intermediate that is stabilized by activatorQ59071495
Transcription of herpes simplex type 1 DNA in nuclei isolated from infected HEp-2 and KB cellsQ68689479
Mutational dissection of the HSV-1 immediate-early protein Vmw175 involved in transcriptional transactivation and repressionQ69836417
Mechanism of action of an acidic transcriptional activator in vitroQ70113517
A genetic approach to promoter recognition during trans induction of viral gene expressionQ70147104
TFII is required for transcription of the naturally TATA-less but initiator-containing Vbeta promoterQ71142774
Interaction of calmodulin with myosin light chain kinase and cAMP-dependent protein kinase in bovine brainQ72902847
Identification of elongation factor-1alpha as a Ca2+/calmodulin-binding protein in Tetrahymena ciliaQ73210414
DCAMKL1, a brain-specific transmembrane protein on 13q12.3 that is similar to doublecortin (DCX)Q22008801
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activatorsQ22009365
Composite co-activator ARC mediates chromatin-directed transcriptional activationQ22009528
Subregions of the adenovirus E1A transactivation domain target multiple components of the TFIID complexQ24311556
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complexQ24313231
Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cellsQ24529064
The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activatorQ24622776
Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteinsQ24630637
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
A generic protein purification method for protein complex characterization and proteome explorationQ27861087
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.Q27930548
A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.Q27931243
SAGA binds TBP via its Spt8 subunit in competition with DNA: implications for TBP recruitmentQ27934876
The tandem affinity purification (TAP) method: a general procedure of protein complex purificationQ28131621
Mammalian Srb/Mediator complex is targeted by adenovirus E1A proteinQ28198008
Structure, function, and activator-induced conformations of the CRSP coactivatorQ28217949
Matrin 3 is a Ca2+/calmodulin-binding protein cleaved by caspasesQ28238072
Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USFQ28252370
The general transcription factors of RNA polymerase IIQ28298663
In-gel digestion for mass spectrometric characterization of proteins and proteomesQ29547583
Five intermediate complexes in transcription initiation by RNA polymerase IIQ29616444
The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal gangliaQ33783767
The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1.Q33788934
Nuclear accumulation of IE62, the varicella-zoster virus (VZV) major transcriptional regulatory protein, is inhibited by phosphorylation mediated by the VZV open reading frame 66 protein kinaseQ33798767
Herpes simplex virus type 1 ICP4 promotes transcription preinitiation complex formation by enhancing the binding of TFIID to DNAQ33812313
Oct-2 facilitates functional preinitiation complex assembly and is continuously required at the promoter for multiple rounds of transcriptionQ34041038
Transcription factors: global and detailed viewsQ34141508
Phosphorylation of transcription factor Sp1 during herpes simplex virus type 1 infectionQ34341046
Multiple interactions between hTAFII55 and other TFIID subunits. Requirements for the formation of stable ternary complexes between hTAFII55 and the TATA-binding proteinQ34388525
The mammalian Mediator complex and its role in transcriptional regulationQ34419211
Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptidesQ34503856
The general transcription machinery and general cofactorsQ34549899
ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expressionQ34773141
The Herpes Simplex Virus 1 U S 3 Protein Kinase Blocks Caspase-Dependent Double Cleavage and Activation of the Proapoptotic Protein BADQ34997331
TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoterQ35033681
Association of the herpes simplex virus regulatory protein ICP4 with specific nucleotide sequences in DNA.Q35048694
Transcriptional control of herpesvirus gene expression: gene functions required for positive and negative regulationQ35585442
The regulation of synthesis and properties of the protein product of open reading frame P of the herpes simplex virus 1 genomeQ35839814
Functional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4Q35845959
US3 of herpes simplex virus type 1 encodes a promiscuous protein kinase that phosphorylates and alters localization of lamin A/C in infected cellsQ35857210
The mediator of RNA polymerase II.Q36029267
Structure of eukaryotic Mediator complexesQ36129167
Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptidesQ36129181
Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175Q36506573
Herpes simplex virus infected cell polypeptide 4 preferentially represses Sp1-activated over basal transcription from its own promoterQ36597197
RNA polymerase II is aberrantly phosphorylated and localized to viral replication compartments following herpes simplex virus infectionQ36627034
Effect of the transcription start region of the herpes simplex virus type 1 latency-associated transcript promoter on expression of productively infected neurons in vivo.Q36634708
Physical interaction between the herpes simplex virus type 1 immediate-early regulatory proteins ICP0 and ICP4.Q36638050
The ICP4 binding sites in the herpes simplex virus type 1 glycoprotein D (gD) promoter are not essential for efficient gD transcription during virus infectionQ36690288
The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infectionQ36810975
trans-dominant inhibition of herpes simplex virus transcriptional regulatory protein ICP4 by heterodimer formationQ36812486
The herpes simplex virus 1 protein kinase encoded by the US3 gene mediates posttranslational modification of the phosphoprotein encoded by the UL34 geneQ36820600
Separation of primary structural components conferring autoregulation, transactivation, and DNA-binding properties to the herpes simplex virus transcriptional regulatory protein ICP4Q36830312
Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID.Q36846156
Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4.Q36853238
Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulationQ36854125
Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27.Q36873101
Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4.Q36875525
Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) proteinQ36882457
Binding of the herpes simplex virus immediate-early gene product ICP4 to its own transcription start siteQ36885717
Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functionsQ36888472
Promoter domains required for expression of plasmid-borne copies of the herpes simplex virus thymidine kinase gene in virus-infected mouse fibroblasts and microinjected frog oocytesQ36891867
Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4Q36892074
Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promotersQ36899046
Isolation of herpes simplex virus regulatory protein ICP4 as a homodimeric complexQ36903194
Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.Q36908396
Effects of deletions on expression of the herpes simplex virus thymidine kinase gene from the intact viral genome: the amino terminus of the enzyme is dispensable for catalytic activityQ36917427
DNA-binding properties of a herpes simplex virus immediate early proteinQ36928244
Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activationQ36994683
Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase geneQ37527308
Functional interaction and colocalization of the herpes simplex virus 1 major regulatory protein ICP4 with EAP, a nucleolar-ribosomal proteinQ37597734
Varicella-zoster virus open reading frame 66 protein kinase and its relationship to alphaherpesvirus US3 kinasesQ37606637
Relationship between TATA-binding protein and herpes simplex virus type 1 ICP4 DNA-binding sites in complex formation and repression of transcriptionQ38292162
Requirements for activation of the herpes simplex virus glycoprotein C promoter in vitro by the viral regulatory protein ICP4.Q38301836
Mediator requirement for both recruitment and postrecruitment steps in transcription initiationQ38329746
An activator binding module of yeast RNA polymerase II holoenzymeQ39445291
Visualization of parental HSV-1 genomes and replication compartments in association with ND10 in live infected cellsQ39648219
The initiator element in a herpes simplex virus type 1 late-gene promoter enhances activation by ICP4, resulting in abundant late-gene expressionQ39682517
Fine-structure mapping of herpes simplex virus type 1 temperature-sensitive mutations within the short repeat region of the genomeQ39814207
Physical and functional interactions between herpes simplex virus immediate-early proteins ICP4 and ICP27.Q39878263
Evidence that herpes simplex virus DNA is transcribed by cellular RNA polymerase BQ39975490
Repression of activator-mediated transcription by herpes simplex virus ICP4 via a mechanism involving interactions with the basal transcription factors TATA-binding protein and TFIIB.Q40016568
Interaction of the viral activator protein ICP4 with TFIID through TAF250.Q40019074
Localization of a 34-amino-acid segment implicated in dimerization of the herpes simplex virus type 1 ICP4 polypeptide by a dimerization trap.Q40041005
ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB.Q40046433
Activities of heterodimers composed of DNA-binding- and transactivation-deficient subunits of the herpes simplex virus regulatory protein ICP4Q40062603
Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cellsQ40065340
Regulation of herpesvirus macromolecular synthesis V. Properties of α polypeptides made in HSV-1 and HSV-2 infected cellsQ40069571
Characterization of transcription-deficient temperature-sensitive mutants of herpes simplex virus type 1Q40206986
Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsKQ40218879
A detailed analysis of an HSV-1 early promoter: sequences involved in trans-activation by viral immediate-early gene products are not early-gene specificQ40455122
Differential cellular requirements for activation of herpes simplex virus type 1 early (tk) and late (gC) promoters by ICP4.Q40551612
The regions of the herpes simplex virus type 1 immediate early protein Vmw175 required for site specific DNA binding closely correspond to those involved in transcriptional regulationQ40557511
Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activityQ41587905
A predictive model for DNA recognition by the herpes simplex virus protein ICP4Q41679975
Connexin 32 of gap junctions contains two cytoplasmic calmodulin-binding domainsQ41811628
Identification of proteins phosphorylated directly by the Us3 protein kinase encoded by herpes simplex virus 1Q42589734
Binding of ICP4, TATA-binding protein, and RNA polymerase II to herpes simplex virus type 1 immediate-early, early, and late promoters in virus-infected cellsQ43064400
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)5733-5744
P577publication date2011-03-30
P1433published inJournal of VirologyQ1251128
P1476titleHerpes simplex virus 1 ICP4 forms complexes with TFIID and mediator in virus-infected cells
P478volume85

Reverse relations

cites work (P2860)
Q40161346A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts.
Q26996418A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation
Q30250926A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication
Q37631525A targeted RNA interference screen reveals novel epigenetic factors that regulate herpesviral gene expression
Q37550178CTCF interacts with the lytic HSV-1 genome to promote viral transcription.
Q36073807Characterization of cis-acting elements required for autorepression of the equine herpesvirus 1 IE gene
Q37997767Contribution of MS-Based Proteomics to the Understanding of Herpes Simplex Virus Type 1 Interaction with Host Cells.
Q36434189Functional Characterization of the Serine-Rich Tract of Varicella-Zoster Virus IE62.
Q38086860HSV-1 ICP22: hijacking host nuclear functions to enhance viral infection
Q58995392HSV-1 as a Model for Emerging Gene Delivery Vehicles
Q83227615Herpes simplex viral nucleoprotein creates a competitive transcriptional environment facilitating robust viral transcription and host shut off
Q26745059Herpesvirus Late Gene Expression: A Viral-Specific Pre-initiation Complex Is Key
Q36694202ICP4-induced miR-101 attenuates HSV-1 replication
Q28544797IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications
Q36736766Infection by Herpes Simplex Virus 1 Causes Near-Complete Loss of RNA Polymerase II Occupancy on the Host Cell Genome
Q35786606Investigating the biology of alpha herpesviruses with MS-based proteomics
Q112286875Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription
Q35586902Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cells
Q36884872Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions
Q36251434Replication-Coupled Recruitment of Viral and Cellular Factors to Herpes Simplex Virus Type 1 Replication Forks for the Maintenance and Expression of Viral Genomes
Q39248110Requirement of the N-terminal activation domain of herpes simplex virus ICP4 for viral gene expression
Q47221477Role of L-Particles during Herpes Simplex Virus Infection
Q35643936Selective recruitment of nuclear factors to productively replicating herpes simplex virus genomes
Q59356645Temporal Viral Genome-Protein Interactions Define Distinct Stages of Productive Herpesviral Infection
Q35023569Temporal association of herpes simplex virus ICP4 with cellular complexes functioning at multiple steps in PolII transcription
Q28118789The EHV-1 UL4 protein that tempers viral gene expression interacts with cellular transcription factors
Q36023187The Epstein-Barr virus BcRF1 gene product is a TBP-like protein with an essential role in late gene expression.
Q38766628The Impact of Mass Spectrometry-Based Proteomics on Fundamental Discoveries in Virology.
Q39365625The N terminus and C terminus of herpes simplex virus 1 ICP4 cooperate to activate viral gene expression
Q35192700The histone acetyltransferase CLOCK is an essential component of the herpes simplex virus 1 transcriptome that includes TFIID, ICP4, ICP27, and ICP22.
Q38971182Time-resolved Global and Chromatin Proteomics during Herpes Simplex Virus Type 1 (HSV-1) Infection
Q39246210Viral gene products actively promote latent infection by epigenetic silencing mechanisms
Q36506791mRNA decay during herpes simplex virus (HSV) infections: mutations that affect translation of an mRNA influence the sites at which it is cleaved by the HSV virion host shutoff (Vhs) protein

Search more.