Crystal structure of human Mediator subunit MED23

scientific article published in Nature Communications

Crystal structure of human Mediator subunit MED23 is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2018NatCo...9.3389M
P356DOI10.1038/S41467-018-05967-Y
P932PMC publication ID6107663
P698PubMed publication ID30140054

P50authorJan SteyaertQ28050902
Els PardonQ28320519
Alexis VergerQ46716588
Didier MontéQ56872770
Prakash RucktooaQ57198443
Vincent VilleretQ58139963
P2093author name stringBernard Clantin
Frédérique Dewitte
Zoé Lens
P2860cites workSubunit architecture and functional modular rearrangements of the transcriptional mediator complexQ24298604
External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivatorQ24538358
PHENIX: a comprehensive Python-based system for macromolecular structure solutionQ24654617
Architecture of the Mediator head moduleQ27670658
Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase IIQ27674569
Structure of the Mediator head moduleQ27683221
Architecture of the RNA polymerase II-Mediator core initiation complexQ27697899
Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation ComplexQ27728022
XDSQ27860472
Features and development of CootQ27861079
Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0Q27861104
Mammalian Srb/Mediator complex is targeted by adenovirus E1A proteinQ28198008
Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunitQ28213019
A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction.Q30913240
Molecular architecture of the yeast Mediator complexQ34495543
Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunitQ34651988
A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replicationQ34945388
A general protocol for the generation of Nanobodies for structural biologyQ34979957
Selective requirement for Mediator MED23 in Ras-active lung cancerQ36339876
The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determinationQ36394676
Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone developmentQ36768663
Interactions between subunits of the Mediator complex with gene-specific transcription factorsQ37917031
Mediator Architecture and RNA Polymerase II Interaction.Q38724799
Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFbQ39206646
Wrenchnolol derivative optimized for gene activation in cellsQ39872079
Core Mediator structure at 3.4 Å extends model of transcription initiation complexQ41598083
Mediator structure and rearrangements required for holoenzyme formation.Q41598892
Opposing effects of Elk-1 multisite phosphorylation shape its response to ERK activationQ42320390
Mediator complex regulates alternative mRNA processing via the MED23 subunit.Q42630238
A Gene-Expression Inhibitor that Targets an α-Helix-Mediated Protein InteractionQ44412506
sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval inductionQ48070632
MED23 mutation links intellectual disability to dysregulation of immediate early gene expressionQ48932486
Roll: a new algorithm for the detection of protein pockets and cavities with a rolling probe sphere.Q50596388
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageQuantQ112270642
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectgeneral chemistryQ909510
intellectual disability, autosomal recessive 18Q109933168
P304page(s)3389
P577publication date2018-08-23
P1433published inNature CommunicationsQ573880
P1476titleCrystal structure of human Mediator subunit MED23
P478volume9

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cites work (P2860)
Q92651096The Structures of Eukaryotic Transcription Pre-initiation Complexes and Their Functional Implications
Q64231631Twenty years of Mediator complex structural studies