Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors

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Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/0008-5472.CAN-10-2705
P8608Fatcat IDrelease_6u5aurkqcnfa3mfefxhnv4q74u
P3181OpenCitations bibliographic resource ID3735635
P932PMC publication ID3074499
P698PubMed publication ID21324921
P5875ResearchGate publication ID49839592

P2093author name stringSnorri S Thorgeirsson
Anthony J Scarzello
Jesper B Andersen
Jimmy K Stauffer
Jonathan M Weiss
Rachel L De Kluyver
Robert H Wiltrout
Timothy C Back
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Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesisQ33623036
Obesity is associated with a higher risk of clear-cell renal cell carcinoma than with other histologiesQ33636256
A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseasesQ33789567
Cancer gene discovery in hepatocellular carcinomaQ34002120
Progenitor-derived hepatocellular carcinoma model in the rat.Q34037698
Activation of beta-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis.Q34114761
beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance.Q34302259
Experimental models of hepatocellular carcinomaQ34345987
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomasQ34380511
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotypeQ34619635
Distinct pathways of genomic progression to benign and malignant tumors of the liver.Q35970966
Induction of ovarian cancer by defined multiple genetic changes in a mouse model systemQ36496578
Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver diseaseQ36820197
Role of cyclin D1 as a mediator of c-Met- and beta-catenin-induced hepatocarcinogenesisQ37065772
Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene.Q37132646
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implicationsQ37160617
PTEN at the crossroad of metabolic diseases and cancer in the liver.Q37261338
Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology.Q37298654
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A facile method for somatic, lifelong manipulation of multiple genes in the mouse liverQ39988585
EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinomaQ40006245
Subtype classification of hepatocellular adenomaQ43112827
Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvementQ44666331
Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancerQ46520772
Body size and risk of epithelial ovarian and related cancers: a population-based case-control studyQ47235553
Prognostic significance of beta-catenin nuclear expression in hepatocellular carcinomaQ47236438
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling.Q52087746
Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis.Q53341563
Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.Q54443542
Gene Expression Profiles of Serous, Endometrioid, and Clear Cell Subtypes of Ovarian and Endometrial CancerQ62112715
IFN-gamma-dependent delay of in vivo tumor progression by Fas overexpression on murine renal cancer cellsQ73289660
Serine phosphorylation-regulated ubiquitination and degradation of beta-cateninQ73735409
Akt phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular carcinomaQ81128776
Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinomaQ81329832
Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumorsQ82499265
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)2718-27
P577publication date2011-04-01
P1433published inCancer ResearchQ326097
P1476titleCoactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors
P478volume71

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