scholarly article | Q13442814 |
P2093 | author name string | Xin Chen | |
Diego F Calvisi | |||
P2860 | cites work | Co-expression and regulation of Met and Ron proto-oncogenes in human hepatocellular carcinoma tissues and cell lines | Q73491986 |
Epidemiology of hepatocellular carcinoma | Q73541726 | ||
Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin | Q73773421 | ||
Molecular pathogenesis of human hepatocellular carcinoma | Q74543031 | ||
The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma | Q82176065 | ||
On the role of notch1 and adult hepatocytes in murine intrahepatic cholangiocarcinoma development | Q86484678 | ||
Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma | Q24556510 | ||
Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors | Q24620075 | ||
mTOR: from growth signal integration to cancer, diabetes and ageing | Q24633662 | ||
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach | Q24633776 | ||
Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace | Q26858820 | ||
Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies | Q27002547 | ||
Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma | Q27478395 | ||
Sorafenib in advanced hepatocellular carcinoma | Q27861075 | ||
The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors | Q28214940 | ||
Targeting the IL-6 dependent phenotype can identify novel therapies for cholangiocarcinoma | Q28476545 | ||
Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling | Q28513138 | ||
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines | Q28975767 | ||
Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells | Q29617246 | ||
Cancer stem cells: models and concepts | Q29620611 | ||
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice | Q29620765 | ||
Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo. | Q33180754 | ||
Effect of genome size on AAV vector packaging | Q33730405 | ||
Genetics of hepatocellular carcinoma | Q33998184 | ||
Cancer gene discovery in hepatocellular carcinoma | Q34002120 | ||
Synergistic role of sprouty2 inactivation and c-Met up-regulation in mouse and human hepatocarcinogenesis | Q34062598 | ||
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas | Q34067016 | ||
Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse | Q34144518 | ||
Oncogene-specific formation of chemoresistant murine hepatic cancer stem cells | Q34233172 | ||
Role of BMI1, a stem cell factor, in cancer recurrence and chemoresistance: preclinical and clinical evidences. | Q34247788 | ||
Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models | Q34266365 | ||
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer | Q34357796 | ||
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas | Q34380511 | ||
Bmi1 is required for hepatic progenitor cell expansion and liver tumor development | Q34431278 | ||
Hepatocellular carcinoma: an epidemiologic view | Q34528348 | ||
Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma. | Q34632966 | ||
Investigation of oncogenic cooperation in simple liver-specific transgenic mouse models using noninvasive in vivo imaging. | Q34652500 | ||
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice | Q34661807 | ||
Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis | Q34672049 | ||
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma. | Q34672477 | ||
Self-complementary AAV vectors; advances and applications | Q34804660 | ||
Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system. | Q34821616 | ||
Risk factors for cholangiocarcinoma | Q35074664 | ||
Orthotopic models of cancer for preclinical drug evaluation: advantages and disadvantages | Q35761435 | ||
Aberrant CpG Island Hypermethylation Along Multistep Hepatocarcinogenesis | Q35792134 | ||
The AAV vector toolkit: poised at the clinical crossroads | Q35876224 | ||
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma | Q35945177 | ||
Distinct pathways of genomic progression to benign and malignant tumors of the liver. | Q35970966 | ||
Cholangiocarcinomas can originate from hepatocytes in mice | Q36129118 | ||
Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling. | Q36336041 | ||
Exploring genomic profiles of hepatocellular carcinoma. | Q36393332 | ||
Contributions of human tumor xenografts to anticancer drug development | Q36439483 | ||
Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials | Q36622291 | ||
Molecular pathology of biliary tract cancers | Q36636828 | ||
WNT/beta-catenin signaling in liver health and disease | Q36804161 | ||
Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment | Q36900063 | ||
Role of cyclin D1 as a mediator of c-Met- and beta-catenin-induced hepatocarcinogenesis | Q37065772 | ||
Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma | Q37177871 | ||
Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma | Q37246194 | ||
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice | Q37303897 | ||
Sorafenib for the treatment of unresectable hepatocellular carcinoma | Q37368694 | ||
Role of alcohol in liver carcinogenesis | Q37456531 | ||
Experimental mouse models for hepatocellular carcinoma research | Q37574072 | ||
Mouse models of hepatocellular carcinoma | Q37696404 | ||
AAV-mediated gene therapy for liver diseases: the prime candidate for clinical application? | Q37825907 | ||
Cholangiocarcinoma: epidemiology, risk factors, pathogenesis, and diagnosis | Q37832697 | ||
Strategies for hepatocellular carcinoma therapy and diagnostics: lessons learned from high throughput and profiling approaches. | Q37857056 | ||
Cholangiocarcinoma--controversies and challenges | Q37860916 | ||
Genetics of hepatobiliary carcinogenesis | Q37871482 | ||
Mouse models for liver cancer. | Q38083387 | ||
Inactivation of Spry2 accelerates AKT-driven hepatocarcinogenesis via activation of MAPK and PKM2 pathways. | Q39344238 | ||
AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/ | Q39459058 | ||
Bmi1 functions as an oncogene independent of Ink4A/Arf repression in hepatic carcinogenesis | Q39771415 | ||
A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver | Q39988585 | ||
Hydroporation as the mechanism of hydrodynamic delivery | Q40014713 | ||
Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties | Q40262786 | ||
Sprouty 2, an inhibitor of mitogen-activated protein kinase signaling, is down-regulated in hepatocellular carcinoma. | Q40314354 | ||
The ras/mitogen-activated protein kinase pathway inhibitor and likely tumor suppressor proteins, sprouty 1 and sprouty 2 are deregulated in breast cancer. | Q40519865 | ||
Efficient lentiviral transduction of liver requires cell cycling in vivo | Q40909303 | ||
Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes | Q41626792 | ||
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system | Q41734970 | ||
Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: implications for the treatment of human liver cancer. | Q41832567 | ||
Priming of hepatocytes enhances in vivo liver transduction with lentiviral vectors in adult mice | Q42424129 | ||
In vivo correction of murine tyrosinemia type I by DNA-mediated transposition. | Q44260023 | ||
Helper-Independent Sleeping Beauty transposon-transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo | Q44845534 | ||
Adjuvant gemcitabine therapy improves survival in a locally induced, R0-resectable model of metastatic intrahepatic cholangiocarcinoma | Q45266560 | ||
In vivo correction of murine hereditary tyrosinemia type I by phiC31 integrase-mediated gene delivery. | Q45280308 | ||
High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice | Q45779177 | ||
HBx gene of hepatitis B virus induces liver cancer in transgenic mice | Q45852802 | ||
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. | Q45861628 | ||
Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1. | Q46232274 | ||
Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer | Q46520772 | ||
gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway | Q46853179 | ||
A critical role for notch signaling in the formation of cholangiocellular carcinomas. | Q50945875 | ||
A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration. | Q51071233 | ||
Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice. | Q52221306 | ||
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. | Q53206297 | ||
Hepatic Stem-like Phenotype and Interplay of Wnt/β-Catenin and Myc Signaling in Aggressive Childhood Liver Cancer | Q56762983 | ||
Chronic Bile Duct Injury Associated with Fibrotic Matrix Microenvironment Provokes Cholangiocarcinoma in p53-Deficient Mice | Q58214837 | ||
Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations | Q64379604 | ||
c-myc amplification in hepatocellular carcinoma predicts unfavorable prognosis | Q71134011 | ||
Difference in gene expression for matrix metalloproteinase-1 between early and advanced hepatocellular carcinomas | Q73107801 | ||
Involvement of the Ets-1 gene in overexpression of matrilysin in human hepatocellular carcinoma | Q73263453 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | liver cancer | Q623031 |
P304 | page(s) | 912-923 | |
P577 | publication date | 2014-01-28 | |
P1433 | published in | The American Journal of Pathology | Q4744259 |
P1476 | title | Hydrodynamic transfection for generation of novel mouse models for liver cancer research | |
P478 | volume | 184 |
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Q36778814 | A Hippo and Fibroblast Growth Factor Receptor Autocrine Pathway in Cholangiocarcinoma |
Q48091492 | A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma |
Q46519493 | A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis. |
Q59790534 | A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment |
Q39167037 | A shortcut for early macrophage recruitment into tumors by activated oncogenes |
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Q36372357 | Anti-tumor Efficiency of Lipid-coated Cisplatin Nanoparticles Co-loaded with MicroRNA-375 |
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Q45059708 | Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells. |
Q64039535 | CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling |
Q52427794 | CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice. |
Q43088347 | Central role of mTORC1 downstream of YAP/TAZ in hepatoblastoma development |
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Q96817624 | Cholangiocarcinoma 2020: the next horizon in mechanisms and management |
Q92898129 | Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans |
Q36560210 | Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice. |
Q35832927 | Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver |
Q91656784 | Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma |
Q36916485 | Comparison of liver oncogenic potential among human RAS isoforms |
Q51396277 | Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma. |
Q47387974 | Cytoplasmic localization of the cell polarity factor Scribble supports liver tumor formation and tumor cell invasiveness. |
Q47377422 | DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma. |
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Q35907583 | Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background. |
Q36922232 | Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans. |
Q37231321 | Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin |
Q35740123 | Distinct anti-oncogenic effect of various microRNAs in different mouse models of liver cancer |
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Q49952320 | Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model. |
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Q58108213 | Focal adhesion kinase activation limits efficacy of Dasatinib in c-Myc driven hepatocellular carcinoma |
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Q92965169 | GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling |
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Q41549513 | Hepatic Loss of Borealin Impairs Postnatal Liver Development, Regeneration, and Hepatocarcinogenesis |
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